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Molecular Microbiology, ISSN 0950-382X, 01/2018, Volume 107, Issue 2, pp. 198 - 213
Journal Article
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 03/2011, Volume 31, Issue 3, pp. 976 - 985
Using a modified MK-801 (dizocilpine) N-methyl-D-aspartic acid (NMDA) receptor hypofunction model for schizophrenia, we analyzed glycolysis, as well as... 
Alanine
Journal Article
Biochimica et Biophysica Acta: Proteins and Proteomics, ISSN 1570-9639, 07/2010, Volume 1804, Issue 7, pp. 1424 - 1431
Cystathionine b-synthase (CBS) catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of l-serine and l-homocysteine to form l-cystathionine in the... 
Alanine
Journal Article
Immunology Letters, ISSN 0165-2478, 11/2010, Volume 134, Issue 1, pp. 17 - 25
a- Perturbation in IFNI[sup3R2 internalization reinstates IFN-I[sup3 sensitivity in T cells. a- LI255-256 is an internalization motif of IFNI[sup3R2 used in T... 
Alanine
Journal Article
Journal of Physiology, ISSN 0022-3751, 09/2008, Volume 586, Issue 17, p. 4061
The [beta]-alanine carrier was characterized functionally in the 1960s to 1980s at the luminal surface of the ileal mucosal wall and is a Na.sup.+- and... 
Alanine
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 2006, Volume 17, Issue 24, pp. 3380 - 3385
(+)-Carpamic acid [(2′ ,5′ ,6′ )-8-(5′-hydroxy-6′-methylpiperidin-2′-yl)octanoic acid, ] was synthesized from ( )-alanine, employing intramolecular and... 
Alanine
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 6, pp. 511 - 520
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e20374 - e20374
Background: In an effort to discover new drugs to treat tuberculosis (TB) we chose alanine racemase as the target of our drug discovery efforts. In... 
INACTIVATION | DESIGN | MECHANISM | CYCLOSERINE | ENZYMES | MULTIDISCIPLINARY SCIENCES | MULTIDRUG-RESISTANT TUBERCULOSIS | GROWTH | DRUGS | SALMONELLA-TYPHIMURIUM | DERIVATIVES | Alanine Racemase - antagonists & inhibitors | Anti-Infective Agents - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Enzyme Inhibitors - analysis | Alanine Racemase - metabolism | Mycobacterium tuberculosis - drug effects | Microbial Sensitivity Tests | Substrate Specificity - drug effects | Alanine Racemase - chemistry | Anti-Infective Agents - analysis | Anti-Infective Agents - chemistry | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - classification | Mass Spectrometry | Inhibitory Concentration 50 | Alanine Dehydrogenase - metabolism | Cell Death - drug effects | HeLa Cells | Kinetics | Anti-Infective Agents - classification | Alanine Racemase - pharmacology | High-Throughput Screening Assays - methods | Amino acids | Tuberculosis | Enzyme inhibitors | Drug discovery | Cells | Drugs | Salmonella | Antimicrobial activity | Dehydrogenases | Toxicity | High-throughput screening | Cytotoxicity | Biochemistry | Biosynthesis | Suicide | Antiinfectives and antibacterials | Mammalian cells | D-Alanine | L-Alanine | Inhibition | Suicide substrates | Enzymes | Alanine racemase | Alanine | Cell walls | Peptidoglycans | Feasibility studies | Substrate inhibition | Antimicrobial agents | Permeability | Lead compounds | Substrates | Screening | Inhibitors | Cellular structure | Index Medicus
Journal Article
European Journal of Plant Pathology, ISSN 0929-1873, 09/2009, Volume 125, Issue 1, pp. 97 - 107
The molecular basis of resistance to benzimidazole fungicides with laboratory and field mutant isolates of Botrytis cinerea was investigated. After chemical... 
Alanine
Journal Article
PLoS ONE, 11/2013, Volume 8, Issue 11
HNP1 is a human alpha defensin that forms dimers and multimers governed by hydrophobic residues, including Tyr16, Ile20, Leu25, and Phe28. Previously, alanine... 
Alanine
Journal Article
PLoS ONE, 11/2013, Volume 8, Issue 11
Complex regional pain syndrome (CRPS) is a chronic, progressive, and devastating pain syndrome characterized by spontaneous pain, hyperalgesia, allodynia,... 
Alanine
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Purpose The purpose of this study was to evaluate the metabolomic changes in 3D-cultured human mesenchymal stem cells (hMSCs) in alginate beads, so as to... 
Alanine
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Increasing epidemiological evidence has indicated that inherited variations of mitochondrial DNA (mtDNA) copy number affect the genetic susceptibility of many... 
Alanine
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Non-conserved amino acids that are far removed from the active site can sometimes have an unexpected effect on enzyme catalysis. We have investigated the... 
Alanine
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Bone Morphogenetic Protein 15 (BMP15) is a TGF beta -like oocyte-derived growth factor involved in ovarian folliculogenesis as a critical regulator of many... 
Alanine
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Staphylococcus aureus is a dangerous human pathogen. A number of the proteins secreted by this bacterium are implicated in its virulence, but many of the... 
Alanine
Journal Article
Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 2, p. 324
(1) Background: D-alanine-D-alanine ligase (DdlA), an effective target for drug development to combat against Mycobacterium tuberculosis (Mtb), which threatens... 
Mycobacterium | Peptidoglycan | D-alanine-D-alanine ligase | TARGET | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | D-CYCLOSERINE | CHEMISTRY, MULTIDISCIPLINARY | peptidoglycan | SMEGMATIS | METABOLOMICS | ENZYME | BIOSYNTHESIS | PENICILLIN-BINDING PROTEINS | DIAMINOPIMELATE | Substrate Specificity | Peptide Synthases - genetics | Adenosine Triphosphate - metabolism | Enzyme Inhibitors - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Biological Assay | Dipeptides - metabolism | Recombinant Proteins - metabolism | Bacterial Proteins - antagonists & inhibitors | Gene Expression | Bacterial Proteins - genetics | Alanine - metabolism | Recombinant Proteins - genetics | Plasmids - metabolism | Peptide Synthases - metabolism | Protein Interaction Mapping | Escherichia coli - genetics | Mycobacterium tuberculosis - enzymology | Plasmids - chemistry | Protein Binding | Bacterial Proteins - metabolism | Kinetics | Peptide Synthases - antagonists & inhibitors | Mycobacterium tuberculosis - genetics | Biological properties | Alanine | Escherichia coli | Orthophosphate | Peptidoglycans | Health risks | High-throughput screening | Crosslinking | Colorimetry | Drug development | Assaying | Substrates | Proteins | Thin layer chromatography | Screening | D-Alanine | Tuberculosis | Inhibitors | D-Alanine-D-alanine ligase | D-Alanyl-D-alanine | Dimerization | Polyhistidine | Index Medicus | d-alanine">">d-alanine | d-alanine ligase">">d-alanine ligase
Journal Article
PLoS ONE, 09/2013, Volume 8, Issue 9
Mammals and plants share pathogen-sensing systems named nod-like receptors (NLRs). Some NLRs form the inflammasome, a protein scaffold that regulates the... 
Alanine
Journal Article
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