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Journal of gastroenterology and hepatology, ISSN 0815-9319, 03/2009, Volume 24, Issue 3, pp. 443 - 452
Background and Aims:  We examined extrinsic and intrinsic (endogenous) mitochondrial apoptosis pathways in experimental non‐alcoholic steatohepatitis (NASH).... 
mitochondria | methionine and choline deficiency | insulin‐like growth factor‐1 | TRAIL‐R killer/DR5 | TNF receptors | cell death pathways | p53 | Cell death pathways | TRAIL-R killer/DR5 | Methionine and choline deficiency | Mitochondria | Insulin-like growth factor-1 | P53 | HEPATOCYTE APOPTOSIS | ACIDS | DR5 | insulin-like growth factor-1 | NONALCOHOLIC STEATOHEPATITIS | LIVER-DISEASE | PATHOGENESIS | NECROSIS | TNF-ALPHA | LIGAND | GASTROENTEROLOGY & HEPATOLOGY | TRAIL-R killer | NF-KAPPA-B | HEPATIC STEATOSIS | Liver - pathology | Liver - enzymology | Fatty Liver - pathology | Mitochondria, Liver - metabolism | Caspase 3 - metabolism | Choline Deficiency - complications | Male | Alanine Transaminase - blood | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | RNA, Messenger - metabolism | fas Receptor - metabolism | Tumor Suppressor Protein p53 - genetics | Time Factors | Receptors, Tumor Necrosis Factor, Type II - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Nutritional Status | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | BH3 Interacting Domain Death Agonist Protein - metabolism | Disease Models, Animal | Methionine - deficiency | Receptors, Tumor Necrosis Factor - metabolism | Fatty Liver - metabolism | Mitochondria, Liver - pathology | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Tumor Suppressor Protein p53 - metabolism | Mitochondria, Liver - enzymology | Animals | Mice | bcl-X Protein - metabolism | Insulin-Like Growth Factor I - metabolism | Apoptosis | Fatty Liver - etiology | BH3 Interacting Domain Death Agonist Protein, metabolism | Receptors, Tumor Necrosis Factor, Type II, metabolism | Fatty Liver, pathology | Mitochondria, Liver, metabolism | Receptors, Tumor Necrosis Factor, metabolism | Cyclin-Dependent Kinase Inhibitor p21, metabolism | Insulin-Like Growth Factor I, metabolism | Caspase 3, metabolism | Antigens, CD95, metabolism | RNA, Messenger, metabolism | Tumor Suppressor Protein p53, metabolism | Methionine, deficiency | Choline Deficiency, complications | Tumor Suppressor Protein p53, genetics | bcl-X Protein, metabolism | Mitochondria, Liver, pathology | Liver, pathology | Alanine Transaminase, blood | Liver, metabolism | Fatty Liver, metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand, metabolism | Liver, enzymology | Fatty Liver, etiology | Mitochondria, Liver, enzymology | Receptors, Tumor Necrosis Factor, Type I, metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand, genetics | Messenger RNA | Choline | Methionine | Mitochondrial DNA | Tumor proteins | Peptide hormones | Growth factors
Journal Article
Antioxidants & redox signaling, ISSN 1523-0864, 12/2011, Volume 15, Issue 11, pp. 2837 - 2854
Hepatic energy depletion has been described in severe sepsis, and lipopolysaccharide (LPS) has been shown to cause mitochondrial DNA (mtDNA) damage. To clarify... 
Original Research Communications | OXIDATIVE STRESS | LIVER-INJURY | PEROXYNITRITE | MANGANESE SUPEROXIDE-DISMUTASE | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | ETHANOL | MICE | TRANSCRIPTION-FACTOR | RESPIRATORY FACTOR-I | EXPRESSION | Aconitate Hydratase - metabolism | Electron Transport Complex III - metabolism | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Humans | Tumor Necrosis Factor-alpha - blood | Alanine Transaminase - blood | Electron Transport Complex I - metabolism | Tyrosine - analogs & derivatives | Electron Transport Complex IV - metabolism | DNA-Binding Proteins - metabolism | Nitric Oxide Synthase Type II - antagonists & inhibitors | Sepsis - metabolism | Adenosine Triphosphate - metabolism | ATP Synthetase Complexes - metabolism | Nitrites - blood | Transcription, Genetic | Superoxide Dismutase - metabolism | Iron - blood | Nitrates - blood | DNA, Mitochondrial - metabolism | High Mobility Group Proteins - metabolism | Liver - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Thiobarbituric Acid Reactive Substances - metabolism | Iron - metabolism | Toll-Like Receptor 4 - metabolism | Hep G2 Cells | Transcription Factors - metabolism | Tyrosine - metabolism | Animals | Interferon-beta - pharmacology | Nitric Oxide Synthase Type II - genetics | Lipopolysaccharides - pharmacology | Interferon-beta - blood | Mice | Nitric Oxide Synthase Type II - metabolism | DNA damage | Physiological aspects | Septic shock | Mitochondrial DNA | Genetic aspects | Research | Health aspects | Risk factors | Lipopolysaccharides
Journal Article
BMC plant biology, ISSN 1471-2229, 10/2012, Volume 12, Issue 1, pp. 189 - 189
Journal Article
PloS one, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0179036
.... This study investigated the effects of four salinities (0 %, 6 %, 12 % and 18 %) on gonadal development, osmoregulation and metabolism of adult male E... 
ANIMAL-TISSUES | NA+/K+-ATPASE ACTIVITY | IONIC REGULATION | K+-ATPASE | MULTIDISCIPLINARY SCIENCES | SEAWATER ACCLIMATION | LITOPENAEUS-VANNAMEI | FREE AMINO-ACIDS | GILLS | CARCINUS-MAENAS | FRESH-WATER | Malondialdehyde - metabolism | Sodium-Potassium-Exchanging ATPase - genetics | Uric Acid - metabolism | Gonads - drug effects | Lipoproteins, HDL - metabolism | Brachyura - growth & development | Hemolymph - metabolism | Gills - metabolism | Male | gamma-Glutamyltransferase - metabolism | Osmoregulation - drug effects | RNA, Messenger - metabolism | Fatty Acids, Omega-6 - metabolism | Amino Acids - metabolism | Sodium-Potassium-Exchanging ATPase - metabolism | Brachyura - metabolism | Gills - drug effects | Gonads - metabolism | Salts - pharmacology | Animals | Gonads - growth & development | Glucose - metabolism | Hemolymph - chemistry | Fatty Acids - metabolism | Physiological aspects | Research | Crabs | Salinity | Taurine | Science education | Physiological effects | Polyunsaturated fatty acids | Migration | Zoology | Estuaries | Amino acids | Glucose | Physiological responses | Crustaceans | Arginine | Salinity effects | Physiology | Magnesium | Catadromous species | Malonaldehyde | Enzymes | Alanine | Nutrition | Phenylalanine | Threonine | Gills | Tryptophan | Hemolymph | Osmoregulation | Marine biology | Gender differences | Ecology | Uric acid | Permeability | Brackish water | Metabolism | Gene expression | Na+/K+-exchanging ATPase | Fatty acids | Cholesterol | Studies | Ammonia | Lysine | Ornithine | Females | Aquaculture
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 45, pp. 37673 - 37690
STE20/SPS-1-related proline-alanine-rich protein kinase (SPAK) and oxidative stress-related kinase (OSR1) activate the potassium-dependent sodium-chloride... 
ALANINE-RICH KINASE | ACTIVATION | NA+-CL-COTRANSPORTER | DISTAL TUBULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | NA-K-2CL COTRANSPORTER | DIETARY SALT | ANGIOTENSIN-II | NA+-K+-2CL(-) COTRANSPORTER | BLOOD-PRESSURE | Phosphorylation | Kidney Cortex - metabolism | Receptors, Drug - genetics | Sodium Chloride, Dietary - administration & dosage | Loop of Henle - metabolism | Potassium, Dietary - administration & dosage | Sodium-Potassium-Chloride Symporters - metabolism | Isoenzymes - metabolism | Potassium, Dietary - metabolism | Protein-Serine-Threonine Kinases - metabolism | Sodium Chloride Symporters - metabolism | Gene Expression | Sodium Chloride Symporters - genetics | Isoenzymes - genetics | Protein-Serine-Threonine Kinases - genetics | Sodium-Potassium-Chloride Symporters - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Receptors, Drug - metabolism | Symporters - metabolism | Mice, Knockout | Solute Carrier Family 12, Member 1 | Animals | Solute Carrier Family 12, Member 3 | Sodium Chloride, Dietary - metabolism | Symporters - genetics | Adaptor Proteins, Signal Transducing - genetics | Kidney Medulla - metabolism | Mice | Adaptor Proteins, Signal Transducing - metabolism | Nephrons - metabolism | Kidney Tubules, Distal - metabolism | Hypertension | Sodium Transport | STE20 Kinase | Signal Transduction | Ion Channels | Gitelman's Syndrome | Kidney | Potassium Transport
Journal Article
Diabetes care, ISSN 1935-5548, 2016, Volume 39, Issue 4, pp. 572 - 581
...), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism... 
Journal Article | OVERLOAD | KOREAN NATIONAL-HEALTH | TRANSFERRIN SATURATION | GENE HFE POLYMORPHISMS | INSULIN-RESISTANCE | GLUCOSE-INTOLERANCE | ENDOCRINOLOGY & METABOLISM | SERUM FERRITIN CONCENTRATION | RISK | MELLITUS | HEMOCHROMATOSIS | Multivariate Analysis | Prospective Studies | Follow-Up Studies | gamma-Glutamyltransferase - blood | Humans | Middle Aged | Male | Alanine Transaminase - blood | Case-Control Studies | Diabetes Mellitus, Type 2 - epidemiology | Incidence | Young Adult | C-Reactive Protein - metabolism | Ferritins - metabolism | Ferritins - blood | Aged, 80 and over | Adult | Female | Iron - blood | Risk Factors | Proportional Hazards Models | Biomarkers - blood | Iron - metabolism | Diabetes Mellitus, Type 2 - blood | Aged | Transferrin - metabolism | Type 2 diabetes | Care and treatment | Research | Biological markers | Ferritin | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes | Nutrition and Disease | HNE Voeding en Gezondheid in de Levenscyclus | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | Wereldvoeding | HNE Voeding en Ziekte | HNE Nutrition and Health over the Lifecourse
Journal Article