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Journal Article
Molecular Microbiology, ISSN 0950-382X, 01/2018, Volume 107, Issue 2, pp. 198 - 213
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2016, Volume 108, Issue 3, p. 1
Journal Article
Neurochemical Research, ISSN 0364-3190, 10/2012, Volume 37, Issue 10, pp. 2198 - 2205
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2012, Volume 264, Issue 3, pp. 387 - 394
Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the West. In mice, APAP hepatotoxicity can be rapidly induced with a single... 
Protein adducts | Mitochondria | Acetaminophen | Hepatotoxicity | Oxidant stress | c-Jun‐N-terminal kinase | C-Jun-N-terminal kinase | PEROXYNITRITE | COVALENT BINDING | HEPATIC-NECROSIS | MOUSE HEPATOCYTES | PERMEABILITY TRANSITION | CELL-DEATH | DNA FRAGMENTATION | GLUTATHIONE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | c-Jun-N-terminal kinase | INDUCED HEPATOTOXICITY | Rats, Inbred F344 | Mitochondrial Proteins - genetics | MAP Kinase Kinase 4 - metabolism | Alanine Transaminase - genetics | Analgesics, Non-Narcotic - toxicity | Time Factors | Mitochondrial Proteins - metabolism | Glutamate Dehydrogenase - metabolism | Disease Models, Animal | Acetaminophen - toxicity | Mice, Inbred C57BL | Gene Expression Regulation | Antipyretics - toxicity | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Glutamate Dehydrogenase - genetics | Rats, Sprague-Dawley | Animals | Chemical and Drug Induced Liver Injury - metabolism | MAP Kinase Kinase 4 - genetics | Protein Binding | Mice | Alanine Transaminase - metabolism | Oxidative Stress - drug effects | Oxidative stress | Liver diseases | Liver | Physiological aspects | Mitochondrial DNA | Comparative analysis | Index Medicus | Translocation | Oxidative metabolism | Toxicity | Data processing | Metabolism | Protein turnover | Necrosis | Proteins | c-Jun amino-terminal kinase | Models | Overdose | Intoxication | Injuries | OXIDATION | TRANSLOCATION | INJURIES | MITOCHONDRIA | RATS | TOXICITY | 60 APPLIED LIFE SCIENCES | NECROSIS | METABOLISM | OXIDIZERS | LIVER | MICE | PREFERRED SPECIES | protein adducts | oxidant stress | c-jun-N-terminal kinase | hepatotoxicity | mitochondria
Journal Article
Hepatology, ISSN 0270-9139, 08/2013, Volume 58, Issue 2, pp. 777 - 787
Acetaminophen overdose is a common reason for hospital admission and the most frequent cause of hepatotoxicity in the Western world. Early identification would... 
CIRCULATING MICRORNAS | APOPTOSIS | NECROSIS | OVERDOSE | MARKERS | N-ACETYLCYSTEINE | GASTROENTEROLOGY & HEPATOLOGY | FAILURE | CELL-DEATH | INDUCED HEPATOTOXICITY | KERATIN-18 | Biomarkers | Patients | Liver | Hepatology | Index Medicus | Regeneration | Liver Injury
Journal Article