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Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 07/2014, Volume 66, Issue 7, pp. 975 - 987
Objective Sodium-glucose cotransporter (SGLT) 2 plays an important role in renal glucose reabsorption and has been highlighted as a therapeutic target for the... 
hyperglycaemia | SGLT | diabetes | urinary glucose excretion | ipragliflozin | SGLT2 | PHLORIZIN TREATMENT | MELLITUS | FAMILY | INSULIN | PATHOGENESIS | CLONING | DISEASE | HYPOGLYCEMIA | PHARMACOLOGY & PHARMACY | EXPRESSION | Thiophenes - therapeutic use | Diabetes Mellitus, Experimental - drug therapy | Streptozocin | Male | Diabetes Mellitus, Type 1 - complications | Hyperglycemia - drug therapy | Glucose Intolerance - drug therapy | Glomerular Filtration Rate - drug effects | Liver - drug effects | Glucose Intolerance - etiology | Inflammation - drug therapy | Glucosides - therapeutic use | Diabetes Mellitus, Experimental - complications | Hypoglycemic Agents - therapeutic use | Glucosides - pharmacology | Kidney - drug effects | Albuminuria - etiology | Hyperlipidemias - drug therapy | Thiophenes - pharmacology | Inflammation - etiology | Rats, Sprague-Dawley | Fatty Liver - drug therapy | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemic Agents - pharmacology | Animals | Albuminuria - drug therapy | Hyperlipidemias - etiology | Hyperglycemia - etiology | Oxidative Stress - drug effects | Blood Glucose - metabolism | Fatty Liver - etiology | Oxidative stress | Glucose metabolism | Hyperglycemia | Type 1 diabetes | Liver | Glucose | Health aspects | Dextrose | Diabetes | Sodium | Insulin | Rodents | Index Medicus
Journal Article
Diabetic Medicine, ISSN 0742-3071, 07/2016, Volume 33, Issue 7, pp. 976 - 984
Journal Article
Kidney International, ISSN 0085-2538, 12/2010, Volume 78, Issue 11, pp. 1136 - 1153
The remnant kidney model in C57BL/6 mice does not develop progressive chronic kidney disease (CKD). In this study we modified the model to mimic features of... 
blood pressure | telemetry | glomerulosclerosis | interstitial fibrosis | angiotensin II | ARTERIAL-BLOOD-PRESSURE | LOW-BIRTH-WEIGHT | 9 GENE MYH9 | INDUCED HYPERTENSION | CARDIAC-HYPERTROPHY | UROLOGY & NEPHROLOGY | AFRICAN-AMERICANS | GROWTH-FACTOR | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | CHRONIC-RENAL-FAILURE | MOLECULAR-MECHANISMS | Blood Pressure | Kidney Diseases - physiopathology | Antihypertensive Agents - pharmacology | Tetrazoles - pharmacology | Angiotensin II - administration & dosage | Kidney - pathology | Species Specificity | Hydralazine - pharmacology | Hypertension - drug therapy | Male | Mice, 129 Strain | Angiotensin II Type 1 Receptor Blockers - pharmacology | X-Ray Microtomography | Kidney Diseases - genetics | Hypertension - etiology | Anemia - physiopathology | Albuminuria - physiopathology | Nephrectomy | Time Factors | Glomerulonephritis - etiology | Hypertension - genetics | Glomerulonephritis - physiopathology | Anemia - etiology | Kidney - physiopathology | Disease Models, Animal | Genetic Predisposition to Disease | Infusion Pumps, Implantable | Kidney - drug effects | Albuminuria - etiology | Heart Diseases - physiopathology | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Mice, Inbred C57BL | Desoxycorticosterone | Imidazoles - pharmacology | Sodium Chloride, Dietary | Telemetry | Disease Progression | Hypertension - pathology | Hypertension - physiopathology | Infusions, Subcutaneous | Heart Diseases - etiology | Animals | Fibrosis | Mice | Kidney Diseases - etiology | Blood Pressure Monitoring, Ambulatory | Chronic Disease | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 03/2016, Volume 133, Issue 11, pp. 1058 - 1066
BACKGROUND—Patients with type 1 diabetes mellitus are at increased risk of developing cardiovascular disease (CVD), but they are currently undertreated. There... 
Survival analysis | Cardiovascular diseases | Models, cardiovascular | Risk factors | Diabetes mellitus, type 1 | models | POPULATION | risk factors | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | type 1 | VALIDATION | diabetes mellitus | cardiovascular diseases | cardiovascular | ALL-CAUSE MORTALITY | GLOMERULAR-FILTRATION-RATE | PROGNOSIS RESEARCH | survival analysis | PERIPHERAL VASCULAR DISEASE | COHORT | MULTIPLE IMPUTATION | CORONARY-HEART-DISEASE | Albuminuria - epidemiology | Blood Pressure | Glycated Hemoglobin A - analysis | Peripheral Arterial Disease - etiology | Risk Assessment - methods | Prognosis | Age Factors | Follow-Up Studies | Diabetic Nephropathies - etiology | Humans | Middle Aged | Male | Diabetes Mellitus, Type 1 - complications | Young Adult | Lipids - blood | Statistics, Nonparametric | Aged, 80 and over | Adult | Female | Heart Failure - epidemiology | Heart Failure - etiology | Myocardial Ischemia - epidemiology | Brain Ischemia - epidemiology | Models, Theoretical | Glomerular Filtration Rate | Risk Factors | Brain Ischemia - etiology | Regression Analysis | Myocardial Ischemia - etiology | Peripheral Arterial Disease - epidemiology | Smoking - epidemiology | Diabetes Mellitus, Type 1 - blood | Sex Factors | Denmark - epidemiology | Aged | Diabetic Nephropathies - epidemiology | Clinical trials | Complications and side effects | Usage | Type 1 diabetes | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2016, Volume 71, Issue 5, pp. 530 - 537
Journal Article
Journal of Internal Medicine, ISSN 0954-6820, 03/2015, Volume 277, Issue 3, pp. 362 - 371
ObjectivesSoluble urokinase plasminogen activator receptor (suPAR) is a marker of inflammation and endothelial dysfunction. We investigated the associations... 
diabetic complications | soluble urokinase plasminogen activator receptor | type 1 diabetes | biomarker | inflammation | endothelial dysfunction | Endothelial dysfunction | Diabetic complications | Biomarker | Inflammation | Soluble urokinase plasminogen activator receptor | Type 1 diabetes | MORTALITY | RISK PREDICTION | ALBUMINURIA | SUPAR | MECHANISMS | MEDICINE, GENERAL & INTERNAL | GENERAL-POPULATION | ARTERIAL STIFFNESS | CARDIOVASCULAR-DISEASE | Biomarkers - metabolism | Albuminuria - etiology | Cross-Sectional Studies | Diabetic Nephropathies - etiology | Albuminuria - blood | Humans | Middle Aged | Diabetic Angiopathies - etiology | Male | Diabetes Mellitus, Type 1 - complications | Diabetic Angiopathies - blood | Diabetic Nephropathies - blood | Diabetes Complications - blood | Diabetes Complications - etiology | Receptors, Urokinase Plasminogen Activator - metabolism | C-Reactive Protein - metabolism | Kidney Failure, Chronic - blood | Epidemiologic Methods | Diabetes Mellitus, Type 1 - blood | Female | Kidney Failure, Chronic - etiology | Complications and side effects | Enzymes | Care and treatment | Wave propagation | Analysis | Thrombolytic drugs | Enzyme-linked immunosorbent assay | Myocardial infarction | C-reactive protein | Risk factors | Confidence intervals | Body mass index | Urokinase | Hemoglobin | Stiffness | Blood pressure | Heart diseases | Cerebral infarction | Excretion | Stroke | Adjustment | Complications | Diabetes mellitus | Health risks | Risk analysis | Patients | Cholesterol | Glomerular filtration rate | U-Plasminogen activator | Heart rate | Body mass | Body size | Infarction | Breathing | Diabetes | Wave velocity | Cardiovascular diseases | Health risk assessment | Risk management | Smoking | Index Medicus
Journal Article