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Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2012, Volume 57, pp. 344 - 361
Journal Article
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 08/2012, Volume 303, Issue 3, pp. 297 - 308
.... Aldose reductase modulates cardiac glycogen synthase kinase-3 beta phosphorylation during ischemia-reperfusion... 
Cardioprotection | Aldose reductase | Glycogen synthase kinase 3β | Ischemia reperfusion | DIABETIC COMPLICATIONS | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | aldose reductase | ischemia reperfusion | INJURY | MYOCARDIAL REPERFUSION | HEART | MITOCHONDRIAL PERMEABILITY TRANSITION | INHIBITION | PATHWAY | DOUBLE-EDGED-SWORD | glycogen synthase kinase 3 beta | cardioprotection | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | Protein Kinase C beta | Phosphorylation | Aldehyde Reductase - genetics | Protein Kinase C-alpha - metabolism | Ventricular Function, Left | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Glycogen Synthase Kinase 3 beta | Male | Myocardial Reperfusion Injury - enzymology | Recovery of Function | Myocytes, Cardiac - enzymology | Myocardial Reperfusion Injury - pathology | Transfection | RNA Interference | Protein Kinase C - metabolism | Aldehyde Reductase - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Myocardial Reperfusion Injury - genetics | Phosphatidylinositol 3-Kinase - metabolism | Disease Models, Animal | Cell Line | Protein Kinase C-alpha - antagonists & inhibitors | Aldehyde Reductase - deficiency | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Mice, Inbred C57BL | Mice, Transgenic | Protein Kinase C - antagonists & inhibitors | Glycogen Synthase Kinase 3 - metabolism | Myocardial Reperfusion Injury - physiopathology | Mice, Knockout | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Ventricular Pressure | Myocardial Reperfusion Injury - prevention & control | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Apoptosis | Energetics and Metabolism | glycogen synthase kinase 3β
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 04/2018, Volume 150, pp. 181 - 190
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2009, Volume 4, Issue 8, p. e6535
.... Most recent studies suggest that polyol pathway enzyme, aldose reductase (AR), contributes to the pathogenesis of oxidative stress-induced inflammation by affecting the NF... 
MULTIDISCIPLINARY SCIENCES | Chemokines - biosynthesis | NF-kappa B - antagonists & inhibitors | Aldehyde Reductase - antagonists & inhibitors | Asthma - prevention & control | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | NF-kappa B - metabolism | Hypersensitivity - complications | Enzyme Inhibitors - therapeutic use | Cell Cycle Proteins - antagonists & inhibitors | Animals | Chemokines - antagonists & inhibitors | Inflammation Mediators - metabolism | Asthma - etiology | Inflammation Mediators - antagonists & inhibitors | Mice | Mice, Inbred BALB C | Cytokines - antagonists & inhibitors | Cytokines - biosynthesis | Apoptosis | Medical research | Allergens | Cytokines | Respiratory agents | Inflammation | Polyols | Monosaccharides | Asthma | Prevention | Aldose reductase | Cell death | Nitric oxide | Analysis | Medicine, Experimental | Health aspects | Sugars | Transcription factors | Pathogenesis | Cytotoxicity | Diabetic neuropathy | Biochemistry | Respiratory tract diseases | Pollen | Bioindicators | Inhibition | NF-κB protein | Leukocytes (eosinophilic) | Bronchus | Nitric-oxide synthase | Allergies | Studies | Inhibitors | Aldehyde reductase | Infiltration | Eosinophils | Drugs | Health sciences | Oxidative stress | Animal models | Epithelial cells | Homeostasis | Clinical trials | Lipids | Kinases | Interleukin 6 | Respiratory tract | Immunology | Bronchoalveolar lavage | Rodents | Alveoli | Interleukin 8 | Complications | Diabetes mellitus | Hypersensitivity | Morbidity | Mucin | Diabetes | Cyclooxygenase-2 | Molecular biology | Chemokines
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0134506
Human aldo-keto reductase 1B15 (AKR1B15) is a newly discovered enzyme which shares 92... 
SCORING FUNCTION | SITE | AKR1B10 | METABOLISM | MULTIDISCIPLINARY SCIENCES | FLEXIBILITY | RETINOIC ACID BIOSYNTHESIS | SUPERFAMILY | PROTEINS | BINDING | DEHYDROGENASE | Recombinant Proteins - metabolism | Amino Acid Sequence | Oxidoreductases Acting on Aldehyde or Oxo Group Donors - antagonists & inhibitors | Aldehyde Reductase - antagonists & inhibitors | Aldehyde Reductase - genetics | Humans | Catalytic Domain - genetics | Enzyme Inhibitors - pharmacology | Models, Molecular | Oxidoreductases Acting on Aldehyde or Oxo Group Donors - metabolism | Substrate Specificity | Recombinant Proteins - genetics | Retinaldehyde - metabolism | Aldo-Keto Reductases | Diterpenes | Aldehyde Reductase - metabolism | Protein Conformation | Structural Homology, Protein | Kinetics | Oxidoreductases Acting on Aldehyde or Oxo Group Donors - genetics | Amino Acid Substitution | Catalysis | Analysis | Enzymatic analysis | Structure-activity relationships (Biochemistry) | Phosphorylation | Dehydrogenases | Genes | Lipids | Biochemistry | Biosynthesis | Genomes | Selectivity | Catalytic activity | Retinoids | Hydrophobicity | Proteins | Enzymatic activity | E coli | Substrate specificity | Carbonyls | Recombinant | Amino acid sequence | Substrate inhibition | Retinaldehyde | Metabolism | Substrates | Aldo-keto reductase | Studies | Pets | Organic chemistry | Inhibitors | Acids | Plasmids | Protein expression | Diabetes | Enzyme kinetics | Molecular biology | Binding sites | Cancer | Structure-function relationships
Journal Article