Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4397) 4397
Book Review (526) 526
Publication (517) 517
Book Chapter (29) 29
Newsletter (29) 29
Conference Proceeding (12) 12
Newspaper Article (8) 8
Book / eBook (7) 7
Data Set (1) 1
Dissertation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (3942) 3942
animals (1524) 1524
humans (1464) 1464
biochemistry & molecular biology (1168) 1168
enzymes (953) 953
aldehyde reductase - genetics (923) 923
aldehydes (919) 919
aldehyde reductase - metabolism (763) 763
molecular sequence data (698) 698
male (687) 687
oxidative stress (687) 687
physiological aspects (671) 671
biotechnology & applied microbiology (652) 652
gene expression (615) 615
analysis (587) 587
amino acid sequence (580) 580
metabolism (566) 566
mice (551) 551
aldehyde reductase (545) 545
expression (543) 543
proteins (528) 528
research (524) 524
microbiology (514) 514
aldose reductase (503) 503
genes (491) 491
rats (487) 487
aldehyde oxidoreductases - metabolism (464) 464
aldehyde oxidoreductases - genetics (461) 461
biosynthesis (450) 450
female (447) 447
plant sciences (431) 431
kinetics (420) 420
aldehyde dehydrogenase (404) 404
gene (394) 394
base sequence (392) 392
biotechnology (380) 380
escherichia-coli (380) 380
substrate specificity (371) 371
pharmacology & pharmacy (368) 368
genetic aspects (363) 363
cell biology (360) 360
life sciences (360) 360
aldehydes - metabolism (353) 353
cloning, molecular (347) 347
oxidation-reduction (335) 335
escherichia coli - genetics (312) 312
aldehyde reductase - antagonists & inhibitors (311) 311
aldo-keto reductases (309) 309
alcohol oxidoreductases - genetics (295) 295
reductase (291) 291
fermentation (290) 290
glucose (286) 286
mutation (285) 285
multidisciplinary sciences (281) 281
recombinant proteins - metabolism (280) 280
purification (276) 276
alcohol oxidoreductases - metabolism (274) 274
article (273) 273
plants (269) 269
dehydrogenases (265) 265
protein (264) 264
endocrinology & metabolism (262) 262
research article (257) 257
sugars (250) 250
monosaccharides (248) 248
dehydrogenase (243) 243
toxicology (243) 243
escherichia coli (241) 241
saccharomyces-cerevisiae (239) 239
yeast (236) 236
biochemistry (233) 233
identification (229) 229
sequence homology, amino acid (228) 228
models, molecular (223) 223
cloning (222) 222
aldehyde dehydrogenase - genetics (219) 219
gene-expression (217) 217
bacteria (216) 216
nadp - metabolism (209) 209
cells, cultured (208) 208
arabidopsis-thaliana (206) 206
studies (204) 204
recombinant proteins - genetics (202) 202
ethanol (201) 201
medicine (201) 201
saccharomyces cerevisiae - genetics (200) 200
biochemistry, general (199) 199
enzyme inhibitors - pharmacology (198) 198
rna, messenger - metabolism (198) 198
catalysis (197) 197
cells (193) 193
alcohol (192) 192
phylogeny (192) 192
aldo-keto reductase (191) 191
aldehyde reductase - chemistry (189) 189
middle aged (189) 189
diabetes (187) 187
genetic engineering (187) 187
biophysics (186) 186
cancer (184) 184
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4394) 4394
Chinese (26) 26
Japanese (24) 24
Russian (8) 8
French (5) 5
German (2) 2
Spanish (2) 2
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes
by Atsumi, Shota and Wu, Tung-Yun and Eckl, Eva-Maria and Hawkins, Sarah D and Buelter, Thomas and Liao, James C
Applied Microbiology and Biotechnology, ISSN 0175-7598, 1/2010, Volume 85, Issue 3, pp. 651 - 657
Biofuels synthesized from renewable resources are of increasing interest because of global energy and environmental problems. We have previously demonstrated... 
Biotechnology | Chemistry | Microbiology | Microbial Genetics and Genomics | Metabolic engineering | Biofuel | Alcohol dehydrogenase | Isobutanol | COENZYME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ALCOHOL-DEHYDROGENASE | CRYSTAL-STRUCTURE | YQHD | LACTOCOCCUS-LACTIS | Alcohol Dehydrogenase - metabolism | Recombinant Proteins - metabolism | Butanols - metabolism | Aldehyde Reductase - genetics | Escherichia coli - enzymology | Escherichia coli Proteins - metabolism | Recombinant Proteins - genetics | Fungal Proteins - genetics | Biosynthetic Pathways - genetics | Genetic Engineering | Escherichia coli - genetics | Gene Deletion | Alcohol Dehydrogenase - genetics | Cloning, Molecular | Escherichia coli - metabolism | Escherichia coli Proteins - genetics | Aldehyde Reductase - metabolism | Fungal Proteins - metabolism | Anopheles | Comparative analysis | Biomass energy | Escherichia coli | Vasopressin | Studies | Bacteria | Genes | Index Medicus | Applied Genetics and Molecular Biotechnology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1–Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice
by Wei, Jie and Zhang, Ye and Luo, Yu and Wang, Tao and Wang, Zhen and Bi, Shulin and Song, Dan and Dai, Yuan and Qiu, Longxin and Wen, Longping and Yuan, Li and Yang, James Y
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2014, Volume 67, pp. 91 - 102
Aberrant regulation in oxidative stress, fibrogenesis, and the epithelial–mesenchymal transition (EMT) in renal cells under hyperglycemic conditions... 
Epithelial–mesenchymal transition | Free radicals | Aldose reductase | miR-200a-3p/141-3p | Fibrogenesis | Antioxidant defense | Epithelial-mesenchymal transition | Aldehyde Reductase - genetics | Cytoskeletal Proteins - genetics | Kidney Cortex - metabolism | Transforming Growth Factor beta2 - metabolism | Homeodomain Proteins - metabolism | Transforming Growth Factor beta1 - metabolism | Diabetes Mellitus, Experimental - genetics | Male | MicroRNAs - metabolism | Zinc Finger E-box Binding Homeobox 2 | Kruppel-Like Transcription Factors - metabolism | Aldehyde Reductase - metabolism | Cytoskeletal Proteins - metabolism | NF-E2-Related Factor 2 - genetics | Diabetes Mellitus, Experimental - metabolism | Kelch-Like ECH-Associated Protein 1 | Repressor Proteins - metabolism | Cell Line | Diabetic Nephropathies - pathology | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Repressor Proteins - genetics | Diabetic Nephropathies - genetics | Kidney Cortex - pathology | Mice, Transgenic | Signal Transduction - genetics | Transforming Growth Factor beta1 - genetics | Mesangial Cells - metabolism | Homeodomain Proteins - genetics | Animals | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Mesangial Cells - pathology | Diabetes Mellitus, Experimental - pathology | Mice | MicroRNAs - genetics | Transforming Growth Factor beta2 - genetics | Adaptor Proteins, Signal Transducing - metabolism | Kruppel-Like Transcription Factors - genetics | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Spatially Organized Enzymes Drive Cofactor-Coupled Cascade Reactions
by Ngo, Tien Anh and Nakata, Eiji and Saimura, Masayuki and Morii, Takashi
Journal of the American Chemical Society, ISSN 0002-7863, 03/2016, Volume 138, Issue 9, pp. 3012 - 3021
We report the construction of an artificial enzyme cascade based on the xylose metabolic pathway. Two enzymes, xylose reductase and xylitol dehydrogenase, were... 
XYLOSE | CRYSTAL-STRUCTURE | IN-VIVO | COMPLEXES | NANOSTRUCTURES | DIFFUSION | METABOLIC ENZYMES | SCAFFOLDS | MULTIENZYME SYSTEMS | CHEMISTRY, MULTIDISCIPLINARY | DNA-ORIGAMI STRUCTURES | Recombinant Proteins - metabolism | Xylose - metabolism | Aldehyde Reductase - genetics | D-Xylulose Reductase - genetics | Saccharomyces cerevisiae - genetics | D-Xylulose Reductase - chemistry | Models, Molecular | Recombinant Proteins - chemistry | D-Xylulose Reductase - metabolism | Recombinant Proteins - genetics | DNA - metabolism | Xylose - chemistry | Pichia - enzymology | DNA - genetics | NAD - chemistry | DNA - chemistry | Aldehyde Reductase - chemistry | Pichia - genetics | Saccharomyces cerevisiae - enzymology | Aldehyde Reductase - metabolism | Nucleic Acid Conformation | NAD - metabolism | Enzymes | Research | Cascade reactions | Analysis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The d‐xylose reductase of Hypocrea jecorina is the major aldose reductase in pentose and d‐galactose catabolism and necessary for β‐galactosidase and cellulase induction by lactose
by Seiboth, Bernhard and Gamauf, Christian and Pail, Manuela and Hartl, Lukas and Kubicek, Christian P
Molecular Microbiology, ISSN 0950-382X, 11/2007, Volume 66, Issue 4, pp. 890 - 900
The Hypocrea jecorina d ‐xylose reductase encoding gene xyl1 shows low basal transcript levels, and is induced by d ‐xylose, l ‐arabinose and l ‐arabinitol... 
ASPERGILLUS-NIGER | L-ARABINITOL 4-DEHYDROGENASE | METABOLISM | PATHWAY | TRICHODERMA-REESEI | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | GENE-EXPRESSION | MICROBIOLOGY | PENICILLIUM-CHRYSOGENUM | CELL-FREE-EXTRACTS | TRANSCRIPTIONAL ACTIVATOR XLNR | Gene Expression Regulation, Fungal | Galactose - metabolism | Aldehyde Reductase - genetics | Hypocrea - enzymology | Enzyme Induction | Molecular Sequence Data | Cellulase - biosynthesis | Fungal Proteins - genetics | Sequence Analysis, DNA | Hypocrea - growth & development | Hypocrea - metabolism | Lactose - metabolism | beta-Galactosidase - biosynthesis | Pentoses - metabolism | Hypocrea - genetics | Aldehyde Reductase - metabolism | Fungal Proteins - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Aldose reductase expression as a risk factor for cataract
by Snow, Anson and Shieh, Biehuoy and Chang, Kun-Che and Pal, Arttatrana and Lenhart, Patricia and Ammar, David and Ruzycki, Philip and Palla, Suryanarayana and Reddy, G. Bhanuprakesh and Petrash, J. Mark
Chemico-Biological Interactions, ISSN 0009-2797, 06/2015, Volume 234, pp. 247 - 253
Aldose reductase (AR) is thought to play a role in the pathogenesis of diabetic eye diseases, including cataract and retinopathy. However, not all diabetics... 
AKR1B1 | Cataract | Diabetes | Aldose reductase | UNITED-STATES | BIOCHEMISTRY & MOLECULAR BIOLOGY | RATS | PROTEIN-KINASES | POLYOL PATHWAY | DIABETIC CATARACT | INDUCED OXIDATIVE STRESS | RETINOPATHY | PHARMACOLOGY & PHARMACY | COMPLICATIONS | TOXICOLOGY | LENS | TRANSGENIC MICE | Aldehyde Reductase - genetics | Humans | Diabetes Mellitus, Experimental - genetics | Hyperglycemia - genetics | Sorbitol - metabolism | MAP Kinase Signaling System - genetics | Aldehyde Reductase - metabolism | Diabetes Complications - genetics | Diabetes Mellitus, Experimental - complications | Cataract - enzymology | Diabetes Mellitus, Experimental - metabolism | Insulin - genetics | Cataract - etiology | Diabetes Complications - metabolism | Mice, Inbred C57BL | Risk Factors | Lens, Crystalline - metabolism | Glucose - genetics | Mice, Transgenic | Cataract - metabolism | Hyperglycemia - metabolism | Insulin - metabolism | Animals | Glucose - metabolism | Cataract - genetics | Mice | Apoptosis | Genetic engineering | Risk factors | Sugars | Monosaccharides | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Effects of NADH-preferring xylose reductase expression on ethanol production from xylose in xylose-metabolizing recombinant Saccharomyces cerevisiae
by Lee, Sung-Haeng and Kodaki, Tsutomu and Park, Yong-Cheol and Seo, Jin-Ho
Journal of Biotechnology, ISSN 0168-1656, 04/2012, Volume 158, Issue 4, pp. 184 - 191
► Cofactor-imbalance is a problem in xylose metabolism by recombinant ► NADH-preferable XR, NAD-dependent XDH and XK were overexpressed in Balanced expression... 
Xylose | NADH-preferable xylose reductase | Ethanol | Saccharomyces cerevisiae | STRAINS | XYLITOL DEHYDROGENASE | CONVERSION | PICHIA-STIPITIS | XYLULOKINASE ACTIVITY | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GLUCOSE | GROWTH | FERMENTATION | IMPROVEMENT | Aldehyde Reductase - genetics | D-Xylulose Reductase - genetics | Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae Proteins - biosynthesis | D-Xylulose Reductase - metabolism | Pichia - enzymology | Xylose - genetics | Saccharomyces cerevisiae - metabolism | Pichia - metabolism | Recombination, Genetic | Aldehyde Reductase - metabolism | Genes, Fungal | NADP - metabolism | NAD - metabolism | Transaldolase - genetics | Gene Expression | Metabolic Engineering - methods | NAD - genetics | Xylose - metabolism | Aerobiosis | Ethanol - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Aldehyde Oxidoreductases - genetics | Saccharomyces cerevisiae Proteins - genetics | Fermentation | Mutation - genetics | Transaldolase - metabolism | Aldehyde Oxidoreductases - metabolism | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Xylitol - genetics | D-Xylulose Reductase - biosynthesis | Pichia - genetics | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Xylitol - metabolism | NADP - genetics | Enzymes | Xylitol | Alcohol, Denatured | Alcohol | Sugars | Production data | Monosaccharides | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Direct ethanol production from hemicellulosic materials of rice straw by use of an engineered yeast strain codisplaying three types of hemicellulolytic enzymes on the surface of xylose-utilizing Saccharomyces cerevisiae cells
by Sakamoto, Takatoshi and Hasunuma, Tomohisa and Hori, Yoshimi and Yamada, Ryosuke and Kondo, Akihiko
Journal of Biotechnology, ISSN 0168-1656, 04/2012, Volume 158, Issue 4, pp. 203 - 210
The cost of the lignocellulose-hydrolyzing enzymes used in the saccharification process of ethanol production from biomass accounts for a relatively high... 
Bioethanol | Biomass | Lignocellulose | Cell surface display | XYLANASE | ACID | FUEL ETHANOL | CELLULOSIC BIOMASS | COFERMENTATION | LIQUID HOT-WATER | PRETREATMENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LIGNOCELLULOSIC HYDROLYSATE | FERMENTATION | EXPRESSION | Aldehyde Reductase - genetics | Xylans - metabolism | D-Xylulose Reductase - genetics | Oryza - metabolism | Saccharomyces cerevisiae - genetics | Endo-1,4-beta Xylanases - genetics | Polysaccharides - genetics | Glucuronates - metabolism | D-Xylulose Reductase - metabolism | Pichia - enzymology | Xylose - genetics | Saccharomyces cerevisiae - metabolism | Pichia - metabolism | Lignin - metabolism | beta-Glucosidase - genetics | Glucuronates - genetics | Escherichia coli - metabolism | beta-Glucosidase - metabolism | Aldehyde Reductase - metabolism | Endo-1,4-beta Xylanases - metabolism | Metabolic Engineering - methods | Xylose - metabolism | Ethanol - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Trichoderma - genetics | Oligosaccharides - metabolism | Saccharomyces cerevisiae Proteins - genetics | Fermentation | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Polysaccharides - metabolism | Hydrolysis | Xylans - genetics | Aspergillus oryzae - genetics | Escherichia coli - genetics | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Lignin - genetics | Aspergillus oryzae - metabolism | Oligosaccharides - genetics | Trichoderma - metabolism | Xylitol | Enzymes | Alcohol, Denatured | Alcohol | Production processes | Sugars | Production data | Rice | Alcohols | Monosaccharides | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Human Aldose Reductase Expression Accelerates Atherosclerosis in Diabetic Apolipoprotein E−/− Mice
by Vedantham, Srinivasan and Noh, HyeLim and Ananthakrishnan, Radha and Son, Ni and Hallam, Kellie and Hu, Yunying and Yu, Shuiquing and Shen, Xiaoping and Rosario, Rosa and Lu, Yan and Ravindranath, Thyyar and Drosatos, Konstantinos and Huggins, Lesley Ann and Schmidt, Ann Marie and Goldberg, Ira J and Ramasamy, Ravichandran
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2011, Volume 31, Issue 8, pp. 1805 - 1813
OBJECTIVE—There are several pathways that mediate the aberrant metabolism of glucose and that might induce greater vascular damage in the setting of diabetes.... 
atherosclerosis | endothelial function | aldose reductase | diabetes mellitus | OXIDATIVE STRESS | POLYOL PATHWAY | RAT HEARTS | INHIBITION | ENDOTHELIAL-CELLS | APOE-DEFICIENT MICE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | COMPLICATIONS | HEMATOLOGY | UP-REGULATION | TRANSGENIC MICE | RNA, Small Interfering - genetics | Aldehyde Reductase - genetics | Atherosclerosis - genetics | Humans | DNA, Complementary - genetics | Diabetes Mellitus, Experimental - genetics | Male | Atherosclerosis - etiology | Base Sequence | Aldehyde Reductase - metabolism | Female | Diabetes Complications - genetics | Diabetes Complications - pathology | Vasodilation - physiology | Diabetes Mellitus, Experimental - metabolism | Recombinant Proteins - metabolism | Cell Line | Atherosclerosis - pathology | Gene Expression | Aldehyde Reductase - antagonists & inhibitors | Endothelial Cells - metabolism | Diabetes Complications - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Recombinant Proteins - genetics | Atherosclerosis - metabolism | Diabetes Complications - etiology | Mice, Knockout | Animals | Glucose - metabolism | Mice | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Aldose reductase drives hyperacetylation of EGR-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals
by Vedantham, Srinivasan and Thiagarajan, Devi and Ananthakrishnan, Radha and Wang, Lingjie and Rosario, Rosa and Zou, Yu Shan and Goldberg, Ira and Yan, Shi Fang and Schmidt, Ann Marie and Ramasamy, Ravichandran
Diabetes, ISSN 0012-1797, 02/2014, Volume 63, Issue 2, pp. 761 - 774
Sustained increases in glucose flux via the aldose reductase (AR) pathway have been linked to diabetic vascular complications. Previous studies revealed that... 
DIABETIC COMPLICATIONS | GLUCOSE | ENDOTHELIAL-CELLS | ENDOCRINOLOGY & METABOLISM | ATHEROSCLEROSIS | ACTIVATOR PROTEIN-1 | LYSINE ACETYLATION | NF-KAPPA-B | SIRT1 | TISSUE FACTOR EXPRESSION | TRANSGENIC MICE | Sirtuin 1 - metabolism | Aldehyde Reductase - genetics | Cytokines - metabolism | Humans | Cells, Cultured | Gene Expression Regulation - physiology | Mice, Transgenic | Glucose - pharmacology | Apolipoproteins E - metabolism | Sirtuin 1 - genetics | Hyperglycemia - metabolism | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Nicotinamide Phosphoribosyltransferase - metabolism | Apolipoproteins E - genetics | Early Growth Response Protein 1 - genetics | Aldehyde Reductase - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Cytokines - genetics | Early Growth Response Protein 1 - metabolism | Endothelial Cells - physiology | NAD - metabolism | Enzymes | Hyperglycemia | Aldose reductase | Physiological aspects | Regulation | Acetylation | Health aspects | Homeostasis | Molecules | Diabetes | Glucose | Cell adhesion & migration | Index Medicus | Abridged Index Medicus | Complications
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras–E-cadherin pathway
by Zhang, Wanying and Li, Haonan and Yang, Yihe and Liao, Jie and Yang, Guang-Yu
Cancer Letters, ISSN 0304-3835, 2014, Volume 355, Issue 2, pp. 273 - 280
Abstract Aldo-keto reductase 1B10 (AKR1B10) has relatively specific lipid substrates including carbonyls, retinal and farnesal/geranylgeranial. Metabolizing... 
Hematology, Oncology and Palliative Medicine | Pancreatic adenocarcinoma | KRAS | AKR1B10 | E-cadherin | Migration | Invasion | PROTEIN | METASTASIS | OLEANOLIC ACID | OVEREXPRESSION | CARCINOGENESIS | GENE | ONCOLOGY | EXPRESSION | RNA, Small Interfering - genetics | Up-Regulation | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Aldehyde Reductase - genetics | Pancreatic Neoplasms - metabolism | Cadherins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Oleanolic Acid - pharmacology | ras Proteins - metabolism | Gene Knockdown Techniques | Transfection | Cadherins - genetics | Proto-Oncogene Proteins - metabolism | Aldehyde Reductase - antagonists & inhibitors | Signal Transduction | CD18 Antigens - genetics | Down-Regulation | Pancreatic Neoplasms - pathology | Enzyme Inhibitors - pharmacology | Pancreatic Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Genes, ras | RNA, Small Interfering - administration & dosage | Pancreatic Neoplasms - therapy | Carcinoma | Pancreatic cancer | Analysis | Cancer | Proteins | Signal transduction | Enzymes | Cell growth | Transcription factors | Acids | Rodents | Medical prognosis | Homeostasis | Kinases | Laboratory animals | Index Medicus | migration | pancreatic adenocarcinoma | invasion
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Enhanced production of xylitol from xylose by expression of Bacillus subtilis arabinose:H+ symporter and Scheffersomyces stipitis xylose reductase in recombinant Saccharomyces cerevisiae
by Kim, Hyoju and Lee, Hyun-Soo and Lee, Dae-Hee and Park, Haeseong and Park, Yong-Cheol and Boles, Eckhard and Chung, Donghwa
Enzyme and Microbial Technology, ISSN 0141-0229, 12/2017, Volume 107, pp. 7 - 14
Inefficient transport of xylose into is a major hurdle for production of xylitol, a natural sweetener with five carbons. To facilitate the xylose transport and... 
Xylose | Xylitol | AraE | Saccharomyces cerevisiae | Fed-batch fermentation | XYL1 | PROTEIN | ESCHERICHIA-COLI | IDENTIFICATION | SUGARS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GLUCOSE | FERMENTATION | ETHANOL | STRAIN | HEXOSE TRANSPORTERS | CONSUMPTION | Recombinant Proteins - metabolism | Batch Cell Culture Techniques | Xylose - metabolism | Aldehyde Reductase - genetics | Saccharomyces cerevisiae - genetics | Bacterial Proteins - genetics | Recombinant Proteins - genetics | Fungal Proteins - genetics | Bacillus subtilis - genetics | Saccharomyces cerevisiae - metabolism | Saccharomycetales - genetics | Xylitol - biosynthesis | Arabinose - metabolism | Aldehyde Reductase - metabolism | Bacterial Proteins - metabolism | Kinetics | Saccharomycetales - metabolism | Monosaccharide Transport Proteins - metabolism | Bacillus subtilis - metabolism | Fungal Proteins - metabolism | Monosaccharide Transport Proteins - genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Stereochemical inversion of (S)-reticuline by a cytochrome P450 fusion in opium poppy
by Farrow, Scott C and Hagel, Jillian M and Beaudoin, Guillaume A.W and Burns, Darcy C and Facchini, Peter J
Nature Chemical Biology, ISSN 1552-4450, 09/2015, Volume 11, Issue 9, pp. 728 - 732
The gateway to morphine biosynthesis in opium poppy (Papaver somniferum) is the stereochemical inversion of (S)-reticuline since the enzyme yielding the first... 
SYNTHASE | (S)-TETRAHYDROPROTOBERBERINE OXIDASE | 1,2-DEHYDRORETICULINE | COPTIS-JAPONICA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BENZYLISOQUINOLINE ALKALOID METABOLISM | REDUCTASE | MOLECULAR-CLONING | NOSCAPINE BIOSYNTHESIS | CULTURED-CELLS | MORPHINE ALKALOIDS | Aldehyde Reductase - genetics | Exons | Saccharomyces cerevisiae - genetics | Stereoisomerism | Ligases - genetics | Open Reading Frames | Cytochrome P-450 Enzyme System - metabolism | Molecular Sequence Data | Morphine - biosynthesis | Carbohydrate Epimerases - antagonists & inhibitors | Papaver - genetics | Opium - chemistry | Benzylisoquinolines - chemistry | Saccharomyces cerevisiae - metabolism | Morphinans - metabolism | Bromoviridae - genetics | Base Sequence | Escherichia coli - metabolism | Gene Expression Regulation, Plant | Aldehyde Reductase - metabolism | Opium - metabolism | Plant Proteins - metabolism | Alkaloids - biosynthesis | Recombinant Proteins - metabolism | Morphinans - chemistry | Oxidation-Reduction | Introns | Morphine - chemistry | Ligases - metabolism | Gene Fusion | Recombinant Proteins - genetics | Aldo-Keto Reductases | Plant Proteins - genetics | Benzylisoquinolines - metabolism | Bromoviridae - metabolism | Escherichia coli - genetics | Cytochrome P-450 Enzyme System - genetics | Papaver - metabolism | Carbohydrate Epimerases - genetics | Alkaloids - chemistry | Carbohydrate Epimerases - metabolism | Plant biology | Enzymes | Biosynthesis | Flowers & plants | Narcotics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein-engineered NADH-preferring xylose reductase from Pichia stipitis
by Watanabe, Seiya and Abu Saleh, Ahmed and Pack, Seung Pil and Annaluru, Narayana and Kodaki, Tsutomu and Makino, Keisuke
Microbiology, ISSN 1350-0872, 09/2007, Volume 153, Issue 9, pp. 3044 - 3054
1 Faculty of Engineering, Kyoto University, Kyotodaigaku-katsura, Saikyo-ku, Kyoto 615-8530, Japan 2 Institute of Advanced Energy, Kyoto University, Gokasho,... 
COFACTOR SPECIFICITY | MUTANT | 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE | CANDIDA-TENUIS | FUNCTIONAL EXPRESSION | ALDO-KETO REDUCTASES | FERMENTATION | MICROBIOLOGY | XYLITOL-DEHYDROGENASE | SITE-DIRECTED MUTAGENESIS | COENZYME SPECIFICITY | Transformation, Genetic | Xylose - metabolism | Aldehyde Reductase - genetics | Ethanol - metabolism | Saccharomyces cerevisiae - genetics | Fermentation | Pichia - enzymology | Recombination, Genetic | Pichia - genetics | Protein Engineering | Saccharomyces cerevisiae - enzymology | Aldehyde Reductase - metabolism | Industrial Microbiology - methods | NAD - metabolism | Alcohol, Denatured | Gene mutations | NADH dehydrogenase | Alcohol | Influence | Genetic aspects | Brewer's yeast | Properties | Bacterial genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Genetic association of AKR1B1 gene polymorphism rs759853 with diabetic retinopathy risk: A meta-analysis
by Cao, Mingfeng and Tian, Zhenhua and Zhang, Lin and Liu, Ruiting and Guan, Qingbo and Jiang, Jinjiao
Gene, ISSN 0378-1119, 11/2018, Volume 676, pp. 73 - 78
The study aimed to ascertain the correlation between polymorphism rs759853 and the risk of diabetic retinopathy (DR) through a meta-analysis. Crude odds ratios... 
Diabetic retinopathy | AKR1B1 | Polymorphism | Meta-analysis | DR | SUSCEPTIBILITY | GENETICS & HEREDITY | ALDOSE REDUCTASE GENE | MELLITUS | CHINESE PATIENTS | INDIA | Gene Frequency - genetics | Genetic Predisposition to Disease - genetics | Aldehyde Reductase - genetics | Humans | Risk Factors | Diabetes Mellitus, Type 1 - genetics | Genetic Association Studies - methods | Genotype | Male | Case-Control Studies | Diabetic Retinopathy - genetics | Alleles | Polymorphism, Single Nucleotide - genetics | Aldehyde Reductase - metabolism | Female | Odds Ratio | Endothelial growth factors | Aldose reductase | Nitric oxide | Genetic research | Genetic aspects | Genetic polymorphisms | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights