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Gynecologic Oncology, ISSN 0090-8258, 2013, Volume 132, Issue 2, pp. 474 - 482
Abstract Objective Over-expression of the aldo-keto reductase family 1 member C3 (AKR1C3) has been demonstrated in many human cancers. Lipocalin 2 (LCN2) is... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Lipocalin 2 | Cancer of the uterine cervix | Metastasis | Aldo-keto reductase family 1 member C3 | Matrix metalloproteinase-2 | RADICAL HYSTERECTOMY | PROGNOSTIC-FACTORS | GELATINASE-ASSOCIATED LIPOCALIN | HUMAN-PAPILLOMAVIRUS | OVARIAN-CANCER | DIHYDRODIOL DEHYDROGENASE | OBSTETRICS & GYNECOLOGY | BREAST-CANCER | LUNG-CANCER | ONCOLOGY | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | Lipocalins - biosynthesis | Hydroxyprostaglandin Dehydrogenases - deficiency | Prognosis | Humans | Uterine Cervical Neoplasms - pathology | Acute-Phase Proteins - genetics | Proto-Oncogene Proteins - biosynthesis | Hydroxyprostaglandin Dehydrogenases - metabolism | Cell Movement - physiology | Neoplasm Recurrence, Local - pathology | RNA, Messenger - biosynthesis | Transfection | Uterine Cervical Neoplasms - metabolism | Lipocalins - genetics | HEK293 Cells | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Matrix Metalloproteinase 2 - biosynthesis | 3-Hydroxysteroid Dehydrogenases - deficiency | Cytoskeleton - pathology | Neoplasm Recurrence, Local - metabolism | RNA, Messenger - genetics | Cytoskeleton - genetics | Gene Silencing | Proto-Oncogene Proteins - genetics | Uterine Cervical Neoplasms - genetics | Disease Progression | Hydroxyprostaglandin Dehydrogenases - genetics | Matrix Metalloproteinase 2 - genetics | Aldo-Keto Reductase Family 1 Member C3 | Lipocalin-2 | Cell Line, Tumor | Cytoskeleton - metabolism | Neoplasm Recurrence, Local - genetics | HeLa Cells | 3-Hydroxysteroid Dehydrogenases - genetics | Acute-Phase Proteins - biosynthesis | Development and progression | Cervical cancer | Cancer | Index Medicus
Journal Article
Journal Article
International Journal of Clinical and Experimental Pathology, ISSN 1936-2625, 2012, Volume 5, Issue 4, pp. 278 - 289
Human aldo-keto reductase family 1 member C3 (AKR1C3) was initially identified as a critical enzyme in reducing 5 alpha-dihydrotestosterone (5 alpha-DHT) to 5... 
Adenocarcinoma | Stomach | Squamous cell carcinoma | Gastroesophageal junction | Lung | AKR1C3 | Non-small cell carcinoma | Small cell carcinoma | Esophagus | ANDROGEN RECEPTOR | gastroesophageal junction | POLYCYCLIC AROMATIC-HYDROCARBONS | HUMAN OVARIAN | adenocarcinoma | stomach | PATHOLOGY | DIHYDRODIOL DEHYDROGENASE | lung | ESTROGEN-RECEPTOR-BETA | LUNG-CANCER | non-small cell carcinoma | ONCOLOGY | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE AKR1C3 | TISSUE DISTRIBUTION | PROSTATE-CANCER | small cell carcinoma | REVEALS ROLES | esophagus | squamous cell carcinoma | Immunohistochemistry | Predictive Value of Tests | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oklahoma | 3-Hydroxysteroid Dehydrogenases - analysis | Small Cell Lung Carcinoma - enzymology | Lung Neoplasms - pathology | Male | Stomach Neoplasms - pathology | Esophageal Neoplasms - pathology | Aged, 80 and over | Adult | Female | Stomach Neoplasms - enzymology | Carcinoma, Squamous Cell - enzymology | Diagnosis, Differential | Lung Neoplasms - enzymology | Biomarkers, Tumor - analysis | Adenocarcinoma - enzymology | Esophagogastric Junction - pathology | Esophageal Neoplasms - enzymology | Esophagogastric Junction - enzymology | Small Cell Lung Carcinoma - pathology | Aldo-Keto Reductase Family 1 Member C3 | Hydroxyprostaglandin Dehydrogenases - analysis | Aged | Index Medicus
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2012, Volume 55, Issue 5, pp. 2311 - 2323
Aldo-keto reductase 1C3 (AKR1C3; type 5 17 beta-hydroxysteroid dehydrogenase) is overexpressed in castration resistant prostate cancer (CRPC) and is implicated... 
TARGET | CHEMISTRY, MEDICINAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PURIFICATION | BIOLOGICAL EVALUATION | AKR1C3 | ABIRATERONE ACETATE | 17-BETA-HSD1 | RESISTANT PROSTATE-CANCER | EXPRESSION | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Antineoplastic Agents - chemical synthesis | Humans | Male | Structure-Activity Relationship | Hydroxyprostaglandin Dehydrogenases - metabolism | Fenamates - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | 20-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | 3-Hydroxysteroid Dehydrogenases - metabolism | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - drug therapy | Fenamates - chemistry | Testosterone - biosynthesis | Cyclooxygenase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Hydroxyprostaglandin Dehydrogenases - genetics | Cyclooxygenase Inhibitors - pharmacology | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Aldo-Keto Reductase Family 1 Member C3 | Testosterone - antagonists & inhibitors | Cyclooxygenase 2 - metabolism | Cyclooxygenase Inhibitors - chemical synthesis | Cell Line, Tumor | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Fenamates - chemical synthesis | Cyclooxygenase 1 - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Isoenzymes - antagonists & inhibitors | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 10/2018, Volume 156, pp. 22 - 31
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 10/2017, Volume 276, pp. 194 - 202
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 02/2010, Volume 70, Issue 4, pp. 1573 - 1584
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2011, Volume 437, Issue 1, pp. 53 - 61
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2017, Volume 139, pp. 936 - 946
Journal Article
Journal Article
Journal Article