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1. Biomarkers of heart failure with preserved and reduced ejection fraction
by Senni, Michele and D’Elia, Emilia and Emdin, Michele and Vergaro, Giuseppe
Handbook of Experimental Pharmacology, ISSN 0171-2004, 2017, Volume 243, pp. 79 - 108
Biomarkers are increaingly being used in the management of heart failure not only for the purpose of screening, diagnosis, and risk stratification, but also as... 
Biomarkers | Screening | Prognosis | Diagnosis | Heart failure management | Renin - metabolism | Tumor Necrosis Factor-alpha - metabolism | Catecholamines - metabolism | Humans | Natriuretic Peptide, Brain - metabolism | Cardio-Renal Syndrome - metabolism | Galectin 3 - metabolism | Heart Failure - physiopathology | MicroRNAs - metabolism | beta-N-Acetyl-Galactosaminidase - metabolism | Glycopeptides - metabolism | Creatinine - metabolism | Troponin T - metabolism | Aldosterone - metabolism | C-Reactive Protein - metabolism | Renin-Angiotensin System | Chromogranin A - metabolism | Interleukin-6 - metabolism | Biomarkers - metabolism | Troponin - metabolism | Interleukin-1 - metabolism | Peptide Fragments - metabolism | Angiotensin II - metabolism | Atrial Natriuretic Factor - metabolism | Adrenomedullin - metabolism | Heart Failure - metabolism | Stroke Volume | Lipocalin-2 - metabolism | Hepatitis A Virus Cellular Receptor 1 - metabolism | Interleukin-1 Receptor-Like 1 Protein - metabolism | Growth Differentiation Factor 15 - metabolism | Interleukin-18 - metabolism
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2. Full Text Na,K-ATPase regulation in skeletal muscle
by Pirkmajer, Sergej and Chibalin, Alexander V
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 07/2016, Volume 311, Issue 1, pp. E1 - E31
Skeletal muscle contains one of the largest and the most dynamic pools of Na,K-ATPase (NKA) in the body. Under resting conditions, NKA in skeletal muscle... 
Phospholemman | K-ATPase | Na | Intracellular signaling | Skeletal muscle | Ouabain | ouabain | RAT SOLEUS MUSCLE | PROTEIN-KINASE-C | SODIUM-POTASSIUM TRANSPORT | PHYSIOLOGY | GENE-RELATED PEPTIDE | EXERCISE-INDUCED TRANSLOCATION | NA+-K+-ATPASE | phospholemman | NA+,K+-ATPASE ALPHA-SUBUNIT | BETA-ADRENERGIC MODULATION | Na,K-ATPase | ENDOCRINOLOGY & METABOLISM | intracellular signaling | NICOTINIC ACETYLCHOLINE-RECEPTOR | skeletal muscle | OUABAIN-H-3 BINDING-SITES | Phosphorylation | Sodium-Potassium-Exchanging ATPase - genetics | Humans | Gene Expression Regulation | Hydrocortisone - metabolism | Islet Amyloid Polypeptide - metabolism | Muscle, Skeletal - metabolism | Muscle Fibers, Skeletal - metabolism | Protein Transport | Sodium-Potassium-Exchanging ATPase - metabolism | Aldosterone - metabolism | Insulin - metabolism | Muscle Contraction | Norepinephrine - metabolism | Triiodothyronine - metabolism | Energy Metabolism | Hormones - metabolism | Thyroxine - metabolism | Cell Membrane - metabolism | C-Peptide - metabolism | Epinephrine - metabolism | Physiological aspects | Muscles | Physiological research | Research | Biological control systems | Adenosine triphosphatase
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3. Full Text Effects of various types of anesthesia on hemodynamics, cardiac function, and glucose and lipid metabolism in rats
by Sano, Yusuke and Ito, Shogo and Yoneda, Mamoru and Nagasawa, Kai and Matsuura, Natsumi and Yamada, Yuichiro and Uchinaka, Ayako and Bando, Yasuko K and Murohara, Toyoaki and Nagata, Kohzo
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2016, Volume 311, Issue 6, pp. H1360 - H1366
Anesthesia can affect respiratory, circulatory, and endocrine systems but is necessary for certain experimental procedures such as echocardiography and blood... 
Ketamine-xylazine | Pentobarbital sodium | Isoflurane | pentobarbital sodium | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ketamine-xylazine | MECHANISMS | BODY-TEMPERATURE | COMBINATION | BLOOD-PRESSURE | INSULIN | IMPACT | PERIPHERAL VASCULAR DISEASE | MICE | isoflurane | STRESS | HYPERTENSIVE-RATS | Renin - metabolism | Anesthetics, Dissociative - pharmacology | Isoflurane - pharmacology | Pentobarbital - pharmacology | Male | Fatty Acids, Nonesterified - metabolism | Heart Rate - drug effects | Aldosterone - metabolism | Xylazine - pharmacology | Renin - drug effects | Blood Pressure - drug effects | Dopamine - metabolism | Anesthetics, Inhalation - pharmacology | Angiotensin II - drug effects | Echocardiography | Angiotensin II - metabolism | Cholesterol, HDL - drug effects | Cholesterol, HDL - metabolism | Aorta - drug effects | Insulin Resistance | Rats | Cholesterol, LDL - drug effects | Cholesterol - metabolism | Rats, Sprague-Dawley | Triglycerides - metabolism | Blood Glucose - drug effects | Insulin - metabolism | Animals | Norepinephrine - metabolism | Lipid Metabolism - drug effects | Cholesterol, LDL - metabolism | Glucose - metabolism | Renin-Angiotensin System - drug effects | Hemodynamics - drug effects | Hypnotics and Sedatives - pharmacology | Blood Glucose - metabolism | Ketamine - pharmacology | Epinephrine - metabolism
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4. Full Text Claudins and the kidney
by Yu, Alan S. L
Journal of the American Society of Nephrology, ISSN 1046-6673, 01/2015, Volume 26, Issue 1, pp. 11 - 19
Claudins are tight-junction membrane proteins that function as both pores and barriers in the paracellular pathway in epithelial cells. In the kidney, claudins... 
FLUID REABSORPTION | CALCIUM-SENSING RECEPTOR | EPITHELIAL-CELLS | RABBIT KIDNEY | PROXIMAL CONVOLUTED TUBULE | CORTICAL COLLECTING DUCT | RAT-KIDNEY | UROLOGY & NEPHROLOGY | PARACELLULAR CL-PERMEABILITY | TIGHT JUNCTION PROTEIN | THICK ASCENDING LIMB | Potassium - metabolism | Claudins - genetics | Epithelium - metabolism | Cations - metabolism | Humans | Water - metabolism | Magnesium - metabolism | Permeability | Sodium - metabolism | Polymorphism, Genetic | Aldosterone - metabolism | Kidney - metabolism | Claudins - metabolism | Kidney Tubules, Proximal - metabolism | Salts - metabolism | Mutation | Epithelial Cells - cytology | Nephrons - metabolism | Kidney Diseases - metabolism | Up Front Matters | calcium | calcium-sensing receptor | epithelial | sodium transport | renal proximal tubule cell | cell and transport physiology | renal tubular epithelial cells
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5. Full Text Protective effects of captopril in diabetic rats exposed to ischemia/reperfusion renal injury
by Fouad, Amr A and Al‐Mulhim, Abdulruhman S and Jresat, Iyad and Morsy, Mohamed A
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 02/2013, Volume 65, Issue 2, pp. 243 - 252
Objectives To investigate the potential protective effects of captopril, the angiotensin-converting enzyme inhibitor, in diabetic rats exposed to... 
kidney | diabetes mellitus | ischaemia/reperfusion | rats | captopril | OXIDATIVE STRESS | OXIDANT STRESS | ISCHEMIA-REPERFUSION INJURY | RECEPTOR BLOCKER | CONVERTING ENZYME-INHIBITION | RENIN-ANGIOTENSIN SYSTEM | CARBON-MONOXIDE | PHARMACOLOGY & PHARMACY | HEME OXYGENASE-1 | DECREASES APOPTOSIS | BILIVERDIN REDUCTASE | Tumor Necrosis Factor-alpha - metabolism | Islets of Langerhans - drug effects | Diabetes Mellitus, Experimental - drug therapy | Fas Ligand Protein - metabolism | Kidney - blood supply | Captopril - pharmacology | Kidney - pathology | Glutathione - metabolism | Microtubule-Associated Proteins - metabolism | Caspase 3 - metabolism | Male | NF-kappa B - metabolism | Diabetes Mellitus, Type 2 - metabolism | Reperfusion Injury - blood | Creatinine - metabolism | Aldosterone - metabolism | Insulin-Secreting Cells - metabolism | Kidney - metabolism | Islets of Langerhans - metabolism | Hyperglycemia - pathology | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Diabetes Mellitus, Experimental - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Reperfusion Injury - metabolism | Kidney Diseases - metabolism | Malondialdehyde - metabolism | Kidney - drug effects | Islets of Langerhans - pathology | Reperfusion Injury - pathology | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Aldosterone - blood | Rats | Rats, Sprague-Dawley | Hyperglycemia - metabolism | Insulin - metabolism | Animals | Reperfusion Injury - prevention & control | Hyperglycemia - blood | Insulin-Secreting Cells - drug effects | Creatinine - blood | Diabetes Mellitus, Experimental - pathology | Diabetes Mellitus, Type 2 - pathology | Insulin-Secreting Cells - pathology | Diabetes Mellitus, Type 2 - drug therapy | Nitric Oxide - metabolism | Enzymes | Pancreatic beta cells | Enzyme inhibitors | Ischemia | Captopril | Nitric oxide | Heme | Diabetes | Rodents
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6. Full Text The Aldosterone-Mineralocorticoid Receptor Pathway Exerts Anti-Inflammatory Effects in Endotoxin-Induced Uveitis
by Bousquet, Elodie and Zhao, Min and Ly, André and Leroux les Jardins, Guillaume and Goldenberg, Brigitte and Naud, Marie-Christine and Jonet, Laurent and Besson-Lescure, Bernadette and Jaisser, Frederic and Farman, Nicolette and de Kozak, Yvonne and Behar-Cohen, Francine
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49036
We have previously shown that the eye is a mineralocorticoid-sensitive organ and we now question the role of mineralocorticoid receptor (MR) in ocular... 
CELLS | TUMOR-NECROSIS-FACTOR | NITRIC-OXIDE SYNTHASE | RAT OCULAR-TISSUES | INFLAMMATION | SPIRONOLACTONE | MULTIDISCIPLINARY SCIENCES | DIABETIC-NEPHROPATHY | INHIBITOR | EXPRESSION | CILIARY BODY | Microglia - metabolism | Receptors, Mineralocorticoid - genetics | Ciliary Body - pathology | Intravitreal Injections | Spironolactone - administration & dosage | Receptors, Mineralocorticoid - metabolism | Humans | Endotoxins | Rats, Inbred Lew | Receptors, Glucocorticoid - metabolism | Anti-Inflammatory Agents - metabolism | Aldosterone - administration & dosage | Lipopolysaccharides | Aqueous Humor - metabolism | Spironolactone - pharmacology | Inflammation Mediators - metabolism | Iris - drug effects | Iris - enzymology | Anti-Inflammatory Agents - therapeutic use | Microglia - pathology | Female | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - genetics | Uveitis - metabolism | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Ciliary Body - enzymology | Uveitis - drug therapy | Rats | Aldosterone - pharmacology | Down-Regulation - drug effects | Iris - pathology | Down-Regulation - genetics | Animals | Signal Transduction - drug effects | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - metabolism | Receptors, Glucocorticoid - genetics | Chemokines - metabolism | Aqueous Humor - drug effects | Uveitis - chemically induced | Uveitis - pathology | Enzymes | Anti-inflammatory drugs | Corticosterone | Analysis | Uveitis | Inflammation | Aldosterone | Mitogens | Steroids | Glucocorticoids | Mortality | Adipocytes | Injection | Tumor necrosis factor-α | Macrophages | Gene expression | Microglia | Cell adhesion & migration | Eye | Iris | Rodents | Nitric oxide | γ-Interferon | Down-regulation | Structural damage | Tumor necrosis factor-TNF | Interferon | Diabetes
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7. Full Text Immunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas
by Monticone, Silvia and Castellano, Isabella and Versace, Karine and Lucatello, Barbara and Veglio, Franco and Gomez-Sanchez, Celso E and Williams, Tracy A and Mulatero, Paolo
Molecular and Cellular Endocrinology, ISSN 0303-7207, 08/2015, Volume 411, Issue C, pp. 146 - 154
Adrenal glands removed for unilateral primary aldosteronism (PA) display marked histological heterogeneity. Recently reported somatic mutations in KCNJ5,... 
KCNJ5 | CACNA1D | CYP11B1 immunohistochemistry | ATP1A1 | CYP11B2 immunohistochemistry | Aldosterone producing adenoma | ANTIBODIES | DIAGNOSIS | ADRENAL-CORTEX | HYPERPLASIA | SOMATIC MUTATIONS | CELL BIOLOGY | ZONA GLOMERULOSA | ENDOCRINOLOGY & METABOLISM | KCNJ5 MUTATIONS | UPRIGHT POSTURE | HYPERTENSION | Sodium-Potassium-Exchanging ATPase - genetics | Plasma Membrane Calcium-Transporting ATPases - genetics | Adenoma - genetics | Humans | Hyperaldosteronism - pathology | Middle Aged | Adrenal Cortex - metabolism | Male | Hyperaldosteronism - metabolism | Adrenal Cortex - pathology | Adenoma - metabolism | Plasma Membrane Calcium-Transporting ATPases - metabolism | Aldosterone - metabolism | Adrenocortical Adenoma - genetics | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Adult | Female | Cytochrome P-450 CYP11B2 - metabolism | Hyperaldosteronism - genetics | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Adrenocortical Adenoma - pathology | Adrenocortical Adenoma - metabolism | Sodium-Potassium-Exchanging ATPase - metabolism | Calcium Channels, L-Type - genetics | Steroid 11-beta-Hydroxylase - metabolism | Adenoma - pathology | Calcium Channels, L-Type - metabolism | Genetic aspects | Corticosteroids | Aldosterone | Steroids | ATP2B3
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8. Full Text Multiple aberrant hormone receptors in Cushing's syndrome
by El Ghorayeb, Nada and Bourdeau, Isabelle and Lacroix, André
European Journal of Endocrinology, ISSN 0804-4643, 10/2015, Volume 173, Issue 4, pp. M45 - M60
The mechanisms regulating cortisol production when ACTH of pituitary origin is suppressed in primary adrenal causes of Cushing's syndrome (CS) include diverse... 
PROTEIN-KINASE-A | ALDOSTERONE-PRODUCING ADENOMAS | NODULAR ADRENOCORTICAL-DISEASE | IN-VITRO | MACRONODULAR ADRENAL-HYPERPLASIA | ENDOCRINOLOGY & METABOLISM | CORTISOL SECRETION | GASTRIC-INHIBITORY POLYPEPTIDE | DEPENDENT INSULINOTROPIC PEPTIDE | SOMATIC MUTATIONS | LUTEINIZING-HORMONE | Gene Expression | Receptors, G-Protein-Coupled - metabolism | Humans | Receptors, LH - metabolism | Receptors, Vasopressin - metabolism | Receptors, Glucagon - metabolism | Cushing Syndrome - metabolism | Receptors, Gastrointestinal Hormone - metabolism | Adenoma - metabolism | Receptor, Melanocortin, Type 2 - metabolism | Adrenal Gland Neoplasms - metabolism | Receptors, Serotonin, 5-HT4 - metabolism | Receptors, Adrenergic, beta - metabolism | Cyclic AMP - metabolism
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9. Full Text K⁺ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension
by Murim Choi and Ute I. Scholl and Peng Yue and Peyman Björklund and Bixiao Zhao and Carol Nelson-Williams and Weizhen Ji and Yoonsang Cho and Aniruddh Patel and Clara J. Men and Elias Lolis and Max V. Wisgerhof and David S. Geller and Shrikant Mane and Per Hellman and Gunnar Westin and Göran Åkerström and Wenhui Wang and Tobias Carling and Richard P. Lifton and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Science, ISSN 0036-8075, 2/2011, Volume 331, Issue 6018, pp. 768 - 772
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive hormone production and... 
Depolarization | Hypertension | Somatic mutation | Cell growth | Hyperaldosteronism | REPORTS | Loss of heterozygosity | Adenoma | Genetic mutation | Sequencing | Tumors | REMEDIABLE ALDOSTERONISM | HUMAN BREAST | COLORECTAL CANCERS | ADRENOCORTICAL-CELLS | MULTIDISCIPLINARY SCIENCES | CONDUCTION | GLOMERULOSA CELLS | IDENTIFICATION | MOLECULAR-BASIS | SELECTIVITY | POTASSIUM CHANNEL | Adrenal Glands - pathology | Potassium - metabolism | Cell Proliferation | Humans | Hyperaldosteronism - pathology | Hyperplasia | Protein Multimerization | Zona Glomerulosa - pathology | Male | Hyperaldosteronism - metabolism | Sodium - metabolism | Aldosterone - metabolism | Adrenocortical Adenoma - genetics | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Female | Hypertension - genetics | Adrenal Cortex Neoplasms - metabolism | Cell Line | G Protein-Coupled Inwardly-Rectifying Potassium Channels - chemistry | Hyperaldosteronism - genetics | Mutant Proteins - genetics | Mutant Proteins - metabolism | Zona Glomerulosa - metabolism | Adrenal Cortex Neoplasms - pathology | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Adrenocortical Adenoma - pathology | Adrenocortical Adenoma - metabolism | Hypertension - metabolism | Adrenal Cortex Neoplasms - genetics | Mutant Proteins - chemistry | Mutation | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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10. Full Text Caveolin 1 Modulates Aldosterone‐Mediated Pathways of Glucose and Lipid Homeostasis
by Baudrand, Rene and Gupta, Nidhi and Garza, Amanda E and Vaidya, Anand and Leopold, Jane A and Hopkins, Paul N and Jeunemaitre, Xavier and Ferri, Claudio and Romero, Jose R and Williams, Jonathan and Loscalzo, Joseph and Adler, Gail K and Williams, Gordon H and Pojoga, Luminita H
Journal of the American Heart Association, ISSN 2047-9980, 10/2016, Volume 5, Issue 10, p. n/a
Background Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1)... 
caveolin 1 | mineralocorticoid receptor | dyslipidemia | insulin resistance | aldosterone | eplerenone | Insulin resistance | Caveolin 1 | Eplerenone | Aldosterone | Mineralocorticoid receptor | Dyslipidemia | METABOLIC SYNDROME | OXIDATIVE STRESS | CAVEOLIN-1-DEFICIENT MICE | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | VASCULAR RELAXATION | MINERALOCORTICOID RECEPTOR BLOCKADE | DIETARY-SODIUM | INSULIN-RESISTANCE | ADIPOCYTE DYSFUNCTION | ALDOSE REDUCTASE | Dyslipidemias - genetics | Aldehyde Reductase - genetics | Hypertriglyceridemia - genetics | Resistin - genetics | Receptors, Mineralocorticoid - metabolism | Humans | Middle Aged | Lipoproteins, HDL - metabolism | Homeostasis | Male | RNA, Messenger - metabolism | Young Adult | Adipose Tissue - metabolism | Aldosterone - metabolism | Spironolactone - pharmacology | Mineralocorticoid Receptor Antagonists - pharmacology | Adult | Aldehyde Reductase - metabolism | Female | Lipid Metabolism - genetics | Retinol-Binding Proteins, Plasma - metabolism | Spironolactone - analogs & derivatives | Resistin - metabolism | NADPH Oxidase 4 - genetics | Signal Transduction | Gene Frequency | Liver - metabolism | Caveolin 1 - genetics | Hypertriglyceridemia - metabolism | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Triglycerides - metabolism | Blood Glucose - drug effects | Insulin - metabolism | NADPH Oxidase 4 - metabolism | Animals | Adolescent | Insulin Resistance - genetics | Dyslipidemias - metabolism | Glucose - metabolism | Aged | Mice | Polymorphism, Single Nucleotide | Retinol-Binding Proteins, Plasma - genetics
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11. Full Text Obligatory metabolism of angiotensin II to angiotensin III for zona glomerulosa cell–Mediated relaxations of bovine adrenal cortical arteries
by Kopf, Phillip G and Park, Sang-Kyu and Herrnreiter, Anja and Krause, Christian and Roques, Bernard P and Campbell, William B
Endocrinology, ISSN 0013-7227, 01/2018, Volume 159, Issue 1, pp. 238 - 247
Hyperaldosteronism is associated with hypertension, cardiac hypertrophy, and congestive heart failure. Steroidogenic factors facilitate aldosterone secretion... 
STEROIDOGENESIS | ALDOSTERONE RELEASE | STEROID-SECRETION | ENDOCRINOLOGY & METABOLISM | RAT ADRENALS | AMINOPEPTIDASE | MEDIUM FLOW-RATE | BLOOD-FLOW | RECEPTORS | GLAND | ENDOTHELIAL NITRIC-OXIDE | Endothelium, Vascular - cytology | Gene Expression Regulation, Enzymologic - drug effects | Abattoirs | Muscle, Smooth, Vascular - metabolism | Zona Glomerulosa - drug effects | Adrenal Cortex - metabolism | Endothelium, Vascular - drug effects | Peptide Fragments - pharmacology | Protease Inhibitors - pharmacology | Aldosterone - metabolism | Cattle | Adrenal Cortex - drug effects | Aminopeptidases - metabolism | Arterioles - cytology | Muscle, Smooth, Vascular - drug effects | Aminopeptidases - genetics | Angiotensin II - pharmacology | Peptide Fragments - metabolism | Angiotensin II - metabolism | Cells, Cultured | Zona Glomerulosa - metabolism | Adrenal Cortex - blood supply | Aminopeptidases - antagonists & inhibitors | Angiotensin II - analogs & derivatives | Angiotensin I - metabolism | Muscle, Smooth, Vascular - cytology | Arterioles - drug effects | Zona Glomerulosa - cytology | Angiotensin III - metabolism | Angiotensin II - chemistry | Animals | Arterioles - metabolism | Endothelium, Vascular - metabolism | Peptide Fragments - antagonists & inhibitors | Vasodilation - drug effects | In Vitro Techniques | Angiotensin I - antagonists & inhibitors | Heart | Enzyme activity | Angiotensin III | Adrenal glands | Eicosanoids | Congestive heart failure | Aldosterone | Arteries | Receptors | Metabolites | Enzymatic activity | Adrenal gland | Inhibition | Angiotensin II | Hypertension | Peptidase | Secretion | Cortex | Mass spectroscopy | Liquid chromatography | Metabolism | Blood flow | Angiotensin | Aminopeptidase | Mass spectrometry | Adrenal metabolism | Hypertrophy | Veins & arteries
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12. Full Text Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension
by Ndisang, Joseph Fomusi and Chibbar, Rajni and Lane, Nina
European Journal of Pharmacology, ISSN 0014-2999, 07/2014, Volume 734, Issue 1, pp. 23 - 34
Heart failure and related cardiac complications remains a great health challenge. We investigated the effects of upregulating heme-oxygenase (HO) on myocardial... 
Hypertension | Heme-arginate | Osteopontin | Osteoprotegerin oxidative stress | Inflammation | Heme oxygenase | IMPROVES INSULIN SENSITIVITY | OXIDATIVE STRESS | ATRIAL-NATRIURETIC-PEPTIDE | PHOSPHOLIPASE-C | BODY-COMPOSITION | RAT MODEL | SYSTOLIC BLOOD-PRESSURE | GLUCOSE-METABOLISM | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | INDUCED RENAL INJURY | Antioxidants - metabolism | Cardiotonic Agents - metabolism | Tumor Necrosis Factor-alpha - blood | Male | Dinoprost - metabolism | Tyrosine - analogs & derivatives | Interleukin-1beta - blood | Hypertension - blood | Heme - pharmacology | Aldosterone - metabolism | Heme Oxygenase (Decyclizing) - biosynthesis | Interleukin-6 - blood | Hypertension - chemically induced | Chemokine CCL3 - blood | Enzyme Induction - drug effects | Adiponectin - metabolism | Blood Pressure - drug effects | Dinoprost - analogs & derivatives | Heme Oxygenase (Decyclizing) - metabolism | Extracellular Matrix Proteins - metabolism | Biomarkers - metabolism | Cardiomyopathies - blood | Atrial Natriuretic Factor - metabolism | Endothelin-1 - metabolism | Rats | Cardiomyopathies - pathology | NG-Nitroarginine Methyl Ester - adverse effects | Heart Failure - metabolism | Chemokine CCL2 - blood | Rats, Sprague-Dawley | Hypertension - metabolism | Tyrosine - metabolism | Animals | Cyclic GMP - metabolism | Arginine - pharmacology | Cardiomyopathies - metabolism
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