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European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 11/2017, Volume 109, pp. 21 - 30
The lipophilic phytocannabinoids cannabidiol (CBD) and Δ -tetrahydrocannabinol (THC) show therapeutic efficacy in various medical conditions. Both molecules... 
Cannabinoids | Oral bioavailability | Piperine | SNEDDS | First pass effect | RESVERATROL | CURCUMIN | P-GLYCOPROTEIN | UDP-GLUCURONOSYLTRANSFERASE | IN-VITRO | LIPID-BASED FORMULATIONS | METABOLISM | PHARMACOKINETICS | ENZYMES | PHARMACOLOGY & PHARMACY | Polyunsaturated Alkamides - chemistry | Emulsions | Stilbenes - administration & dosage | Cannabidiol - administration & dosage | Excipients - pharmacokinetics | Nanoparticles - chemistry | Rats, Wistar | Alkaloids - pharmacokinetics | Curcumin - chemistry | Biological Availability | Male | Stilbenes - chemistry | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Drug Delivery Systems | Lipids - chemistry | Excipients - chemistry | Benzodioxoles - pharmacokinetics | Piperidines - pharmacokinetics | Benzodioxoles - chemistry | Cannabidiol - pharmacokinetics | Cannabidiol - chemistry | Piperidines - administration & dosage | Piperidines - chemistry | Gastrointestinal Absorption | Administration, Oral | Curcumin - pharmacokinetics | Lipids - administration & dosage | Dronabinol - pharmacokinetics | Excipients - administration & dosage | Polyunsaturated Alkamides - administration & dosage | Animals | Lipids - pharmacokinetics | Stilbenes - pharmacokinetics | Alkaloids - administration & dosage | Nanoparticles - administration & dosage | Polyunsaturated Alkamides - pharmacokinetics | Dronabinol - administration & dosage | Dronabinol - chemistry | Alkaloids - chemistry | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e14015 - e14015
Background: Dietary supplements have been extensively studied for their beneficial effects on cognition and AD neuropathology. The current study examines the... 
CURCUMIN | MEMORY DEFICITS | AMYLOID-BETA | PIPERINE | BIOLOGY | RATS | TEA POLYPHENOL (-)-EPIGALLOCATECHIN-3-GALLATE | RECOGNITION MEMORY | MICE | TRANSGENIC MODEL | TAU-PATHOLOGY | Memory - drug effects | Thioctic Acid - administration & dosage | Humans | Cerebral Cortex - pathology | Catechin - administration & dosage | Immunoblotting | Hippocampus - drug effects | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Folic Acid - administration & dosage | Vitamin B Complex - administration & dosage | Cerebral Cortex - physiopathology | Amyloid beta-Protein Precursor - metabolism | Cognition - physiology | Cerebral Cortex - drug effects | Acetylcysteine - administration & dosage | Alzheimer Disease - physiopathology | Piperidines - administration & dosage | Brain - physiopathology | Mice, Inbred C57BL | Alzheimer Disease - drug therapy | Ascorbic Acid - administration & dosage | Mice, Transgenic | Hippocampus - pathology | Cognition - drug effects | Maze Learning - drug effects | Mice, Inbred Strains | Brain - drug effects | Polyunsaturated Alkamides - administration & dosage | Amyloid beta-Protein Precursor - genetics | Animals | Brain - pathology | Alkaloids - administration & dosage | Catechin - analogs & derivatives | Mice | Alzheimer Disease - genetics | Dietary Supplements | Hippocampus - physiopathology | Vitamins - administration & dosage | Oligomers | Advertising executives | Catechin | Analysis | Dietary supplements | Acetylcysteine | Models | Genetic engineering | Research | Alzheimer's disease | Folic acid | Lipoic acid | Neurosciences | Memory | Cognitive ability | Neurobiology | Medical services | Cytotoxicity | Cognition | Antioxidants | Proteins | Learning | Ischemia | Transgenic animals | Rodents | Curcumin | Behavior | Neurological disorders | Food | Neurodegenerative diseases | Cortex | Ingredients | Transgenic mice | Studies | Pathology | Epigallocatechin gallate | Diet | β-Amyloid | Alzheimers disease | Hippocampus | Dementia | Index Medicus
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 11/2018, Volume 43, Issue 12, pp. 2399 - 2407
Synthetic cathinones are common constituents of abused "bath salts" preparations and represent a large family of structurally related compounds that function... 
DESIGNER CATHINONES | COCAINE ANALOGS | DRUG | SQUIRREL-MONKEYS | REINFORCING EFFICACY | RHESUS-MONKEYS | PSYCHIATRY | LOCOMOTOR-ACTIVITY | PROGRESSIVE-RATIO SCHEDULES | CONSTITUENT 3,4-METHYLENEDIOXYPYROVALERONE MDPV | NEUROSCIENCES | PHARMACOLOGY & PHARMACY | METHCATHINONE ANALOGS | Dopamine Plasma Membrane Transport Proteins - metabolism | Substance-Related Disorders - metabolism | Pentanones - administration & dosage | Conditioning, Operant - physiology | Pyrrolidines - administration & dosage | Rats | Male | Psychotropic Drugs - administration & dosage | Benzodioxoles - administration & dosage | Rats, Sprague-Dawley | Dopamine Uptake Inhibitors - administration & dosage | Dopamine Plasma Membrane Transport Proteins - antagonists & inhibitors | Dose-Response Relationship, Drug | Street Drugs | Cocaine - administration & dosage | Self Administration | Animals | Conditioning, Operant - drug effects | Substance-Related Disorders - psychology | Alkaloids - administration & dosage | Drugs | Drug abuse | Brain | Salts | Intravenous administration | Dopamine | Narcotics | Serotonin | Methamphetamine | Substrate inhibition | Pharmacology | Selectivity | Drug self-administration | Stimulants | Amphetamine | Serotonin transporter | Correlation analysis | Dopamine transporter | Norepinephrine | Cocaine | Synaptosomes | Inhibition | Pyrrolidine | Transporter
Journal Article
Clinical Nutrition, ISSN 0261-5614, 2015, Volume 34, Issue 6, pp. 1101 - 1108
Summary Background Oxidative stress and inflammation have been proposed as emerging components of metabolic syndrome (MetS). Curcuminoids are natural... 
Gastroenterology and Hepatology | Turmeric | Cardiovascular disease | Antioxidant | Curcuma longa | Randomized controlled trial | C-REACTIVE PROTEIN | OXIDATIVE STRESS | MYOCARDIAL-INFARCTION | RISK | ENDOTHELIAL FUNCTION | IN-VITRO | NUTRITION & DIETETICS | INFLAMMATION | DOUBLE-BLIND | CLINICAL-PRACTICE | ASSOCIATION | Blood Pressure | Meta-Analysis as Topic | Alkaloids - pharmacokinetics | Humans | Middle Aged | Superoxide Dismutase - blood | Biological Availability | Male | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Metabolic Syndrome - drug therapy | C-Reactive Protein - metabolism | Benzodioxoles - pharmacokinetics | Inflammation - drug therapy | Malondialdehyde - blood | Adult | Anti-Inflammatory Agents - administration & dosage | Anti-Inflammatory Agents - pharmacokinetics | Female | Piperidines - pharmacokinetics | Databases, Factual | Body Mass Index | Piperidines - administration & dosage | Double-Blind Method | Curcumin - pharmacokinetics | Polyunsaturated Alkamides - administration & dosage | Antioxidants - administration & dosage | Alkaloids - administration & dosage | Polyunsaturated Alkamides - pharmacokinetics | Oxidative Stress - drug effects | Antioxidants - pharmacokinetics | Dietary Supplements | Antioxidants | Polyphenols | Anti-inflammatory drugs | Analysis | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 2/2017, Volume 234, Issue 4, pp. 589 - 598
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2013, Volume 31, Issue 35, pp. 4400 - 4406
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2014, Volume 20, Issue 8, pp. 2104 - 2114
Purpose: When evaluated in patients with ovarian and other cancer, vintafolide (EC145), a potent folate-targeted vinca alkaloid conjugate, displayed a toxicity... 
OVEREXPRESSION | ONCOLOGY | FOLATE RECEPTOR EXPRESSION | PHASE-II | CONJUGATE | TISSUES | INHIBITORS | ANTITUMOR-ACTIVITY | CELL-LINES | CANCER | EPITHELIAL OVARIAN-CARCINOMA | Folic Acid - pharmacology | Paclitaxel - pharmacology | Taxoids - pharmacology | Humans | Antineoplastic Agents - administration & dosage | Folic Acid - administration & dosage | Cisplatin - administration & dosage | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Vinca Alkaloids - administration & dosage | Vinca Alkaloids - pharmacology | Camptothecin - administration & dosage | Mice, Inbred DBA | Antineoplastic Agents - pharmacology | Paclitaxel - administration & dosage | Camptothecin - analogs & derivatives | Doxorubicin - administration & dosage | Folic Acid - analogs & derivatives | Topotecan - pharmacology | Carboplatin - administration & dosage | Treatment Outcome | Cisplatin - pharmacology | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Taxoids - administration & dosage | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Cell Line, Tumor | Topotecan - administration & dosage | Cell Proliferation - drug effects | Mice, Inbred BALB C | HeLa Cells | Carboplatin - pharmacology | Neoplasms - pathology | Camptothecin - pharmacology | Neoplasms, Experimental - drug therapy | Doxorubicin - pharmacology | Index Medicus
Journal Article
Neurochemical Research, ISSN 0364-3190, 2/2017, Volume 42, Issue 2, pp. 552 - 562
Journal Article
Journal Article