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1. Full Text Association between Serum Perfluorooctanoic Acid (PFOA) and Thyroid Disease in the U.S. National Health and Nutrition Examination Survey
by David Melzer and Neil Rice and Michael H. Depledge and William E. Henley and Tamara S. Galloway
Environmental Health Perspectives, ISSN 0091-6765, 5/2010, Volume 118, Issue 5, pp. 686 - 692
Background: Perfluorooctanoic acid (PFOA, also known as C8) and perfluorooctane sulfonate (PFOS) are stable compounds with many industrial and consumer uses.... 
Chemical hazards | Body mass index | Disease models | Thyroid diseases | Men | Thyroid hormones | Diabetes | Research | Patient assessment | Health surveys | Epidemiology | Human population | Thyroid disease | PFOA | PFOS | thyroid disease | DECANOIC ACID | PERFLUOROALKYL ACIDS | FLUOROCHEMICAL PRODUCTION WORKERS | ENVIRONMENTAL CHEMICALS | RATS | FATTY-ACIDS | human population | AMMONIUM PERFLUOROOCTANOATE | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | BISPHENOL-A | RISK-ASSESSMENT | Fluorocarbons - toxicity | United States - epidemiology | Humans | Middle Aged | Male | Thyroid Diseases - etiology | Environmental Pollutants - blood | Young Adult | Fluorocarbons - blood | Adult | Alkanesulfonic Acids - blood | Female | Environmental Pollutants - toxicity | Caprylates - toxicity | Cross-Sectional Studies | Risk Assessment | Thyroid Diseases - blood | Endocrine Disruptors - blood | Environmental Exposure | Endocrine Disruptors - toxicity | Animals | Health Surveys | Thyroid Diseases - epidemiology | Aged | Alkanesulfonic Acids - toxicity | Caprylates - blood | Diagnosis | Ammonium perfluorooctanoate | Health aspects | Risk factors | Nutrition | Adjustment | Health | Toxicity | Quartiles | Adults | Serums | Index Medicus
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2. Full Text Mixture-specific gene expression in zebrafish (Danio rerio) embryos exposed to perfluorooctane sulfonic acid (PFOS), perfluorohexanoic acid (PFHxA) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB126)
by Blanc, Mélanie and Kärrman, Anna and Kukucka, Petr and Scherbak, Nikolai and Keiter, Steffen and Institutionen för naturvetenskap och teknik and Örebro universitet
Science of the Total Environment, ISSN 0048-9697, 07/2017, Volume 590-591, pp. 249 - 257
Perfluorooctane sulfonic acid (PFOS) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) are persistent organic pollutants of high concern because of their... 
cyp1a | Zebrafish | Lipids | Mixture toxicity | Molecular pathway | PFAS | OXIDATIVE STRESS | PERFLUOROALKYL ACIDS | SUBSTANCES PFASS | cypla | DEVELOPMENTAL TOXICITY | ENVIRONMENTAL SCIENCES | CYTOCHROME-P450 1A | REACTIVE OXYGEN | DIETARY ACCUMULATION | TROUT ONCORHYNCHUS-MYKISS | DRINKING-WATER | PERFLUORINATED COMPOUNDS | Fluorocarbons - toxicity | Animals | Water Pollutants, Chemical - toxicity | Polychlorinated Biphenyls - toxicity | Gene Expression Regulation, Developmental - drug effects | Alkanesulfonic Acids - toxicity | Caproates - toxicity | Embryo, Nonmammalian - drug effects | Zebrafish - genetics | Epigenetic inheritance | Embryonic development | Genes | Permeability | Gene expression | Biological monitoring | Methyltransferases | Physiological aspects | Genetic research | Genetic aspects | Persistent organic pollutants | Tumor proteins | Xenobiotics | Index Medicus | Mixture toxicity PFAS Molecular pathway Zebrafish cyp1a Lipids | Biological Sciences | Miljövetenskap | Naturvetenskap | Biokemi och molekylärbiologi | Biologiska vetenskaper | Enviromental Science | Biochemistry and Molecular Biology | Natural Sciences | Earth and Related Environmental Sciences | Environmental Sciences | Geovetenskap och miljövetenskap
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3. Full Text A review of sources, multimedia distribution and health risks of perfluoroalkyl acids (PFAAs) in China
by Wang, Pei and Wang, Tieyu and Meng, Jing and Liu, Shijie and Lu, Yonglong and Khim, Jong Seong and Giesy, John P
Chemosphere, ISSN 0045-6535, 06/2015, Volume 129, pp. 87 - 99
Perfluoroalkyl acids (PFAAs) have been recognized as emerging pollutants because of their ubiquitous occurrence in the environment, biota and humans. In order... 
Source emission | PFOA | Risk assessment | China | Contamination | PFOS | PERFLUOROOCTANE SULFONATE PFOS | EXTRACTABLE ORGANIC FLUORINE | ENVIRONMENTAL SCIENCES | WATER TREATMENT PLANTS | HUMAN BREAST-MILK | HUMAN EXPOSURE | HUMAN BLOOD | PERFLUORINATED ALKYL ACIDS | TEMPORAL TRENDS | SOUTH CHINA | SPATIAL-DISTRIBUTION | Fluorocarbons - toxicity | Animals | Risk Assessment | Humans | Alkanesulfonic Acids - analysis | Alkanesulfonic Acids - toxicity | Environmental Pollutants - toxicity | Environmental Pollutants - analysis | Fluorocarbons - analysis | Urbanization | Health aspects | Ammonium perfluorooctanoate | Index Medicus | Industrial development | Partitioning | Perfluoroalkyls | Bioaccumulation | Emission | Risk
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4. Full Text Adverse Outcome Pathways during Early Fish Development: A Conceptual Framework for Identification of Chemical Screening and Prioritization Strategies
by Volz, David C and Belanger, Scott and Embry, Michelle and Padilla, Stephanie and Sanderson, Hans and Schirmer, Kristin and Scholz, Stefan and Villeneuve, Daniel
Toxicological Sciences, ISSN 1096-6080, 10/2011, Volume 123, Issue 2, pp. 349 - 358
The fish early life-stage (FELS) test guideline (OECD 210 or OCSPP 850.1400) is the most frequently used bioassay for predicting chronic fish toxicity and... 
High-throughput screening | Fish early life-stage test | Zebrafish embryo | Adverse outcome pathway | fish early life-stage test | AQUATIC ORGANISMS | RAINBOW-TROUT | BEHAVIORAL ALTERATIONS | high-throughput screening | ARYL-HYDROCARBON RECEPTORS | adverse outcome pathway | PRIMARY CULTURES | CHLORPYRIFOS EXPOSURE | LIVER-CELL LINE | LIFE STAGE TOXICITY | zebrafish embryo | TOXICOLOGY | RISK-ASSESSMENT | Polychlorinated Dibenzodioxins - pharmacokinetics | Risk Assessment | Animal Testing Alternatives | Environmental Monitoring - methods | Polychlorinated Dibenzodioxins - classification | Health Priorities | Hazardous Substances - toxicity | Mass Screening - methods | Hazardous Substances - classification | Chlorpyrifos - classification | Hazardous Substances - pharmacokinetics | Toxicity Tests, Chronic | Animals | Alkanesulfonic Acids - pharmacokinetics | Alkanesulfonic Acids - classification | Chlorpyrifos - toxicity | Polychlorinated Dibenzodioxins - toxicity | Alkanesulfonic Acids - toxicity | Chlorpyrifos - pharmacokinetics | Fishes - physiology | Research Design | High-Throughput Screening Assays - methods | Life Cycle Stages - drug effects | Index Medicus
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5. Full Text Effects of endocrine disrupting chemicals on in vitro global DNA methylation and adipocyte differentiation
by Bastos Sales, L and Kamstra, J.H and Cenijn, P.H and van Rijt, L.S and Hamers, T and Legler, J
Toxicology in Vitro, ISSN 0887-2333, 09/2013, Volume 27, Issue 6, pp. 1634 - 1643
Recent studies suggest that endocrine disrupting chemicals (EDCs) may form a risk factor for obesity by altering energy metabolism through epigenetic gene... 
Obesity | Bromodiphenylether | Epigenetics | Tributyltin | Adipocyte differentiation | In vitro | Endocrine disrupting chemicals | STEM-CELLS | MOUSE | 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN | ACTIVATED-RECEPTOR-GAMMA | DIETHYLSTILBESTROL | BISPHENOL-A | TOXICOLOGY | EXPOSURE | 3T3-L1 CELLS | Fluorocarbons - toxicity | Caprylates - toxicity | Benzhydryl Compounds - toxicity | Hydrocarbons, Chlorinated - toxicity | Phenols - toxicity | Humans | Adipocytes - cytology | Adipocytes - drug effects | 3T3-L1 Cells | Hydrocarbons, Brominated - toxicity | Trialkyltin Compounds - toxicity | Endocrine Disruptors - toxicity | Halogenated Diphenyl Ethers - toxicity | Animals | Cell Differentiation - drug effects | Cell Line, Tumor | Alkanesulfonic Acids - toxicity | Diethylstilbestrol - toxicity | Mice | Environmental Pollutants - toxicity | DNA Methylation - drug effects | Methylation | DNA | Index Medicus
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6. Full Text Toxicity of mixtures of perfluorooctane sulphonic acid with chlorinated chemicals and lipid regulators
by Boltes, Karina and Rosal, Roberto and García-Calvo, Eloy
Chemosphere, ISSN 0045-6535, 01/2012, Volume 86, Issue 1, pp. 24 - 29
► Combined toxicity of PFOS, triclosan and pharmaceuticals. ► Most binary mixtures exhibited antagonistic or very antagonistic behaviour. ► Ternary mixtures... 
Combination index | Fibrates | Pseudokirchneriellasubcapitata | Chlorinated compounds | Perfluorooctane sulphonic acid | Pseudokirchneriella subcapitata | TRICLOSAN | PERSONAL CARE PRODUCTS | POLLUTANTS | SURFACTANTS | AQUATIC ENVIRONMENT | ENVIRONMENTAL SCIENCES | PERFLUORINATED ACIDS | SEDIMENT | JAPAN | WATER | Fluorocarbons - toxicity | Mutagens - toxicity | Surface-Active Agents - toxicity | Bezafibrate - toxicity | Lethal Dose 50 | Triclosan - toxicity | Gemfibrozil - toxicity | Chlorophenols - toxicity | Drug Synergism | Water Pollutants, Chemical - toxicity | Hypolipidemic Agents - toxicity | Alkanesulfonic Acids - toxicity | Chlorophyta - drug effects | Complex Mixtures - toxicity | Anti-Infective Agents, Local - toxicity | Regulators | Chlorination | Bioassay | Toxicity | Mathematical analysis | Lipids | Inhibition | Pollutants | Index Medicus
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7. Full Text Comparison of in vitro cytotoxicity, estrogenicity and anti‐estrogenicity of triclosan, perfluorooctane sulfonate and perfluorooctanoic acid
by Henry, Natasha D and Fair, Patricia A
Journal of Applied Toxicology, ISSN 0260-437X, 04/2013, Volume 33, Issue 4, pp. 265 - 272
Concern with increasing levels of emerging contaminants exists on a global scale. Three commonly observed emerging environmental contaminants: triclosan... 
ESCREEN | MCF‐7 BOS cells | triclosan | anti‐estrogenicity | PFOA | estrogenicity | PFOS | Anti-estrogenicity | Triclosan | MCF-7 BOS cells | Estrogenicity | PHARMACEUTICALS | AQUATIC ENVIRONMENT | TOXICITY | PROLIFERATION | WATERS | anti-estrogenicity | HUMAN-MILK | PLASMA | TOXICOLOGY | PERFLUORINATED COMPOUNDS | EXPOSURE | BLOOD | Cell Survival - drug effects | Fluorocarbons - toxicity | Thiazoles - metabolism | Caprylates - toxicity | Humans | Triclosan - toxicity | Estrogen Antagonists - toxicity | Dose-Response Relationship, Drug | Tetrazolium Salts - metabolism | Breast Neoplasms - pathology | Estrogens, Non-Steroidal - toxicity | Cell Line, Tumor | Female | Alkanesulfonic Acids - toxicity | Cell Proliferation - drug effects | Environmental Pollutants - toxicity | Human | Contaminants | Breast | Sulfonates | Assaying | Wildlife management | Ethers | Cancer
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8. Full Text Evaluation of single and joint toxicity of perfluorooctane sulfonate and zinc to Limnodrilus hoffmeisteri: Acute toxicity, bioaccumulation and oxidative stress
by Liu, Jiaoqin and Qu, Ruijuan and Yan, Liqing and Wang, Zunyao and Wang, Liansheng
Journal of Hazardous Materials, ISSN 0304-3894, 01/2016, Volume 301, pp. 342 - 349
Perfluorooctane sulfonate (PFOS) and zinc have been detected in aquatic environment widely. In order to study the combined effects of PFOS and Zn, a series of... 
Oxidative stress | Perfluorooctane sulfonate | Bioaccumulation | Zinc | Acute toxicity | METAL ACCUMULATION | ACID PFOA | FISH CARASSIUS-AURATUS | ENVIRONMENTAL SCIENCES | HEAVY-METAL | CADMIUM | ENGINEERING, ENVIRONMENTAL | TOXICOLOGICAL INTERACTIONS | DAPHNIA-MAGNA | PERFLUORINATED COMPOUNDS | WATER | Biomarkers - metabolism | Malondialdehyde - metabolism | Fluorocarbons - toxicity | Glutathione Peroxidase - metabolism | Water Pollutants, Chemical - pharmacokinetics | Fluorocarbons - pharmacokinetics | Oligochaeta - metabolism | Zinc - pharmacokinetics | Animals | Drug Interactions | Water Pollutants, Chemical - toxicity | Alkanesulfonic Acids - pharmacokinetics | Oligochaeta - drug effects | Zinc - toxicity | Alkanesulfonic Acids - toxicity | Oxidative Stress - drug effects | Superoxide Dismutase - metabolism | Hydrogen-Ion Concentration | Surface active agents | Analysis | Antioxidants | Mortality | Superoxide | Rankings | Index Medicus
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9. Full Text Plasma concentrations of perfluoroalkyl substances and risk of type 2 diabetes: A prospective investigation among U.S. women
by Sun, Qi and Zong, Geng and Valvi, Damaskini and Nielsen, Flemming and Coull, Brent and Grandjean, Philippe
Environmental Health Perspectives, ISSN 0091-6765, 03/2018, Volume 126, Issue 3, p. 037001
BACKGROUND: Emerging evidence suggests that perfluoroalkyl substances (PFASs) are endocrine disruptors and may contribute to the etiology of type 2 diabetes... 
PERFLUOROOCTANOIC ACID EXPOSURE | PERSISTENT ORGANIC POLLUTANTS | NUCLEAR FACTOR 4-ALPHA | ENVIRONMENTAL SCIENCES | ACTIVATED-RECEPTOR-ALPHA | GLUCOSE-HOMEOSTASIS | ENDOCRINE DISRUPTORS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | SERUM CONCENTRATIONS | PPAR-GAMMA | TOXICOLOGY | POSTMENOPAUSAL WOMEN | PERFLUORINATED COMPOUNDS | Fluorocarbons - toxicity | Prospective Studies | Sulfonic Acids - blood | Humans | Sulfonic Acids - toxicity | Case-Control Studies | Environmental Pollutants - blood | Decanoic Acids - toxicity | Environmental Exposure - adverse effects | Fluorocarbons - blood | Diabetes Mellitus, Type 2 - blood | Decanoic Acids - blood | Alkanesulfonic Acids - blood | Diabetes Mellitus, Type 2 - etiology | Female | Alkanesulfonic Acids - toxicity | Environmental Pollutants - toxicity | Odds Ratio | Type 2 diabetes | Women | Pollution | Nurses | Practice | Research | Health aspects | Risk factors | Blood plasma | Endocrine disruptors | Plasma | Physical activity | Seafood | Perfluorodecanoic acid | Body mass index | Demographics | Perfluorooctanoic acid | Perfluoroalkyls | Etiology | Perfluorooctanesulfonic acid | Genetics | Diabetes mellitus (non-insulin dependent) | Medical personnel | Diabetes mellitus | Human exposure | Health risks | Exposure | Breast feeding | Risk analysis | Perfluoro compounds | Acids | Body mass | Womens health | Food intake | Body size | Hormone replacement therapy | Diabetes | Cardiovascular diseases | Cancer
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10. Full Text Toxicological interactions of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) with selected pollutants
by Rodea-Palomares, Ismael and Leganés, Francisco and Rosal, Roberto and Fernández-Piñas, Francisca
Journal of Hazardous Materials, ISSN 0304-3894, 2012, Volume 201, pp. 209 - 218
► PFOA and PFOS interact antagonistically. ► PFOA and PFOS interact in an inverse way with organic pollutants. ► Relative hydrophobicity and antagonism may... 
Combination index | Antagonism | Cyanobacterium | PFOA and PFOS | Synergism | CONTAMINANTS | ASSAY | HEAVY-METALS | SURFACTANTS | TOXICITY | ENVIRONMENTAL SCIENCES | ENGINEERING, ENVIRONMENTAL | PERFLUORINATED COMPOUNDS | Fluorocarbons - chemistry | Fluorocarbons - toxicity | Caprylates - toxicity | Risk Assessment | Chromatography, High Pressure Liquid | Luminescent Measurements | Caprylates - chemistry | Drug Synergism | Environmental Pollutants - chemistry | Alkanesulfonic Acids - toxicity | Molecular Structure | Environmental Pollutants - toxicity | Anabaena - drug effects | Toxicity Tests | Alkanesulfonic Acids - chemistry | Control | Toxicity | Categories | Inverse | Hydrophobicity | Pollutants | Low level | Sulfonic acid | Index Medicus
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11. Full Text A global survey of perfluorinated acids in oceans
by Yamashita, Nobuyoshi and Kannan, Kurunthachalam and Taniyasu, Sachi and Horii, Yuichi and Petrick, Gert and Gamo, Toshitaka
Marine Pollution Bulletin, ISSN 0025-326X, 2005, Volume 51, Issue 8, pp. 658 - 668
Perfluorinated acids and their salts have emerged as an important class of global environmental contaminants. Biological monitoring surveys conducted using... 
BIOTA | ENVIRONMENTAL SCIENCES | FLUORINATED HYDROCARBONS | SURFACE-WATER SAMPLES | MARINE & FRESHWATER BIOLOGY | JAPAN | FISH | PERFLUOROOCTANE SULFONATE | MARINE MAMMALS | RIVER | TANDEM MASS-SPECTROMETRY | BIRDS | Fluorocarbons - toxicity | Mammals - metabolism | Fishes - metabolism | Oceans and Seas | Caprylates - toxicity | Environmental Monitoring - methods | Seawater - chemistry | Water Pollutants, Chemical - analysis | Animals | Water Pollutants, Chemical - toxicity | Caprylates - analysis | Invertebrates - drug effects | Alkanesulfonic Acids - analysis | Environmental Monitoring - statistics & numerical data | Alkanesulfonic Acids - toxicity | Fluorocarbons - analysis
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