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Circulation, ISSN 0009-7322, 06/2013, Volume 127, Issue 25, pp. 2514 - 2522
BACKGROUND—The exact etiology of preeclampsia is unknown, but there is growing evidence of an imbalance in angiogenic growth factors and abnormal placentation.... 
fms-like tyrosine kinase-1 | placental growth factor | hydrogen sulfide | angiogenesis | vascular endothelial growth factor | preeclampsia | fetal development | CARDIAC & CARDIOVASCULAR SYSTEMS | SOLUBLE ENDOGLIN | RISK | ANGIOGENIC FACTORS | WOMEN | SERUM CONCENTRATIONS | TYROSINE KINASE-1 | PREGNANCIES | VASORELAXANT | PERIPHERAL VASCULAR DISEASE | GROWTH-FACTOR | MOUSE PLACENTA | Endothelium, Vascular - cytology | Hydrogen Sulfide - metabolism | Pregnancy Complications, Cardiovascular - physiopathology | Pregnancy, Animal | Glycine - analogs & derivatives | Glycine - adverse effects | Humans | Cystathionine gamma-Lyase - metabolism | Pregnancy Proteins - metabolism | Organothiophosphorus Compounds - pharmacology | Pre-Eclampsia - physiopathology | Antigens, CD - metabolism | Hypertension - etiology | Placenta Diseases - etiology | Young Adult | Endoglin | Pregnancy Complications, Cardiovascular - metabolism | Fetal Development - physiology | Hypertension - chemically induced | Adult | Alkynes - pharmacology | Female | Pre-Eclampsia - metabolism | Organ Culture Techniques | Disease Models, Animal | Fetal Development - drug effects | Mice, Inbred C57BL | Cells, Cultured | Morpholines - pharmacology | Receptors, Cell Surface - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Placenta Diseases - physiopathology | Hypertension - metabolism | Hydrogen Sulfide - antagonists & inhibitors | Placenta - drug effects | Placenta - metabolism | Pregnancy | Neovascularization, Physiologic - physiology | Placenta - physiopathology | Animals | Glycine - pharmacology | Endothelium, Vascular - metabolism | Adolescent | Placenta Growth Factor | Mice | Placenta Diseases - metabolism | Alkynes - adverse effects | Pregnancy Complications, Cardiovascular - etiology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2009, Volume 29, Issue 2, pp. 173 - 179
OBJECTIVE—We explored the effect of hydrogen sulfide (H2S) on atherosclerotic progression, particularly on intracellular adhesion molecule-1 (ICAM-1) in... 
Hydrogen sulfide | Human umbilical vein endothelial cells | Apolipoprotein E knockout mice | Atherosclerosis | Intercellular adhesion molecule-1 | atherosclerosis | apolipoprotein E knockout mice | HYPERCHOLESTEROLEMIA | INHIBITION | hydrogen sulfide | LIFE-STYLE | INFLAMMATION | human umbilical vein endothelial cells | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | CELL-ADHESION MOLECULES | SMOOTH-MUSCLE-CELLS | OXYGENASE | HEMATOLOGY | E-DEFICIENT MICE | EXPRESSION | intercellular adhesion molecule-1 | Hydrogen Sulfide - metabolism | Tumor Necrosis Factor-alpha - metabolism | Glycine - analogs & derivatives | Aorta - ultrastructure | Body Weight | Apolipoproteins E - deficiency | Muscle, Smooth, Vascular - metabolism | Humans | Cystathionine gamma-Lyase - metabolism | Male | NF-kappa B - metabolism | Aorta - metabolism | I-kappa B Proteins - metabolism | RNA, Messenger - metabolism | Foam Cells - drug effects | Dose-Response Relationship, Drug | Endothelial Cells - ultrastructure | Lipids - blood | Alkynes - pharmacology | Intercellular Adhesion Molecule-1 - blood | Active Transport, Cell Nucleus | Cystathionine gamma-Lyase - genetics | Foam Cells - metabolism | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Sulfides - pharmacology | Atherosclerosis - pathology | Endothelial Cells - metabolism | Aorta - drug effects | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Hydrogen Sulfide - blood | Cystathionine gamma-Lyase - antagonists & inhibitors | Atherosclerosis - metabolism | Cardiovascular Agents - pharmacology | Mice, Knockout | Intercellular Adhesion Molecule-1 - metabolism | Animals | Glycine - pharmacology | Apolipoproteins E - genetics | Mice | Atherosclerosis - prevention & control | Endothelial Cells - drug effects | Index Medicus
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2014, Volume 55, Issue 3, pp. 583 - 591
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 03/2014, Volume 25, Issue 3, pp. 569 - 578
Journal Article
Nature, ISSN 0028-0836, 03/2010, Volume 464, Issue 7287, pp. 441 - 444
Journal Article
Glia, ISSN 0894-1491, 02/2017, Volume 65, Issue 2, pp. 231 - 249
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2009, Volume 30, Issue 10, pp. 1523 - 1534
Abstract Hydrogen sulfide (H2 S) is an essential physiological product in brain. We investigated the expression of cystathionine-β-synthase (CBS) and... 
Neurology | Internal Medicine | Alzheimer disease | Parkinson disease | Aging | Neuroinflammation | NaSH | Cystathionine-β-synthase | Microglia | CELLS | ALZHEIMERS-DISEASE BRAIN | OXIDATIVE STRESS | MOUSE | H2S | CYSTATHIONINE BETA-SYNTHASE | NEUROMODULATOR | TOXICITY | NEUROSCIENCES | Cystathionine-beta-synthase | GERIATRICS & GERONTOLOGY | VASORELAXANT | Hydrogen Sulfide - metabolism | Tumor Necrosis Factor-alpha - metabolism | Glycine - analogs & derivatives | Microglia - metabolism | Cystathionine beta-Synthase - antagonists & inhibitors | Humans | Brain - enzymology | Nitrites - metabolism | Cystathionine gamma-Lyase - metabolism | Male | NF-kappa B - metabolism | Astrocytes - enzymology | Neuroprotective Agents - metabolism | Brain - metabolism | Microglia - immunology | Astrocytes - immunology | Aged, 80 and over | Alkynes - pharmacology | Female | Interleukin-6 - metabolism | Hydroxylamine - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Microglia - enzymology | Cystathionine beta-Synthase - metabolism | Cystathionine gamma-Lyase - antagonists & inhibitors | Glycine - pharmacology | Cell Line, Tumor | Aged | Brain - immunology | Astrocytes - metabolism | Hydrogen sulfide | Enzymes | Nervous system diseases | Hydroxides | Parkinson's disease | Anti-inflammatory drugs | Nitrites | Physiological aspects | Alzheimer's disease | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 5, pp. 1821 - 1826
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2015, Volume 65, Issue 2, pp. 501 - 508.e1
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 4, pp. 922 - 932
Hydrogen sulfide (H₂S) is a signalling molecule that belongs to the gasotransmitter family. Two major sources for endogenous enzymatic production of H₂S are... 
nitric oxide | hydrogen sulfide | cystathionine γ‐lyase | pyridoxal‐5′‐phosphate | cystathionine β‐synthase | propargylglycine | aminooxyacetic acid | alanine | β‐cyano | cystathionine γ-lyase | DL-propargylglycine | cystathionine β-synthase | β-cyano-L-alanine | pyridoxal-5′-phosphate | Hydrogen Sulfide - metabolism | Glycine - analogs & derivatives | Cystathionine beta-Synthase - antagonists & inhibitors | Humans | Cystathionine gamma-Lyase - metabolism | Recombinant Fusion Proteins - metabolism | Alanine - analogs & derivatives | Glutathione Transferase - genetics | Alkynes - pharmacology | Aorta, Thoracic - drug effects | Cystathionine gamma-Lyase - genetics | Nitric Oxide Donors - pharmacology | Cystathionine beta-Synthase - genetics | Peptide Fragments - genetics | Alanine - pharmacology | Peptide Fragments - metabolism | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - metabolism | Glutathione Transferase - metabolism | Rats | Cystathionine beta-Synthase - metabolism | Recombinant Fusion Proteins - chemistry | Glutathione Transferase - chemistry | Cystathionine gamma-Lyase - antagonists & inhibitors | Rats, Sprague-Dawley | Hydrogen Sulfide - analysis | Aorta, Thoracic - enzymology | Animals | Glycine - pharmacology | Kinetics | Vasodilation - drug effects | In Vitro Techniques | Nitric Oxide - metabolism | Index Medicus | Research Papers
Journal Article
Biomacromolecules, ISSN 1525-7797, 10/2013, Volume 14, Issue 10, pp. 3581 - 3588
Injectable hydrogels are useful in biomedical applications. We have synthesized hyaluronic acids chemically modified with azide groups (HA-A) and cyclooctyne... 
DESIGN | POLYMER SCIENCE | DRUG-DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | CELL-ADHESION | BIOCOMPATIBLE HYDROGELS | MICHAEL ADDITION | PERITONEAL ADHESIONS | CYCLOADDITIONS | ACID HYDROGELS | DERIVATIVES | SCAFFOLD | Biocompatible Materials - metabolism | NIH 3T3 Cells | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Hyaluronoglucosaminidase - metabolism | Biocompatible Materials - chemistry | Cross-Linking Reagents - pharmacology | Hyaluronic Acid - pharmacology | Male | Structure-Activity Relationship | Azides - chemistry | Cross-Linking Reagents - chemical synthesis | Dose-Response Relationship, Drug | Injections, Subcutaneous | Alkynes - metabolism | Alkynes - pharmacology | Cyclooctanes - pharmacology | Hydrogel, Polyethylene Glycol Dimethacrylate - pharmacology | Molecular Structure | Azides - pharmacology | Azides - metabolism | Copper | Fibroblasts - metabolism | Hydrogel, Polyethylene Glycol Dimethacrylate - metabolism | Cell Survival - drug effects | Click Chemistry | Hyaluronic Acid - chemistry | Injections, Intraperitoneal | Cyclooctanes - metabolism | Alkynes - chemistry | Biocompatible Materials - pharmacology | Hyaluronoglucosaminidase - chemistry | Mice, Inbred ICR | Cross-Linking Reagents - metabolism | Animals | Cyclization | Fibroblasts - drug effects | Hyaluronic Acid - metabolism | Cyclooctanes - chemistry | Hydrogel, Polyethylene Glycol Dimethacrylate - chemical synthesis | Mice | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2017, Volume 110, pp. 291 - 299
Mounting evidence demonstrated deficient cystathionine-γ-lyase (CSE)/H S implicated the development of cardiovascular disease. The present study aimed to... 
Hydrogen sulfide | TXNIP | Endothelial function | MAPK | CELLS | OXIDATIVE STRESS | ANGIOGENESIS | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTATHIONINE-GAMMA-LYASE | ATHEROSCLEROSIS | THIOREDOXIN-INTERACTING PROTEIN | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | HYPERTENSION | Human Umbilical Vein Endothelial Cells | Hydrogen Sulfide - metabolism | Glycine - analogs & derivatives | RNA, Small Interfering - genetics | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Endothelium, Vascular - drug effects | Aorta - metabolism | MAP Kinase Kinase 4 - metabolism | Thioredoxins - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Alkynes - pharmacology | MAP Kinase Kinase 4 - antagonists & inhibitors | Thioredoxins - metabolism | Thioredoxins - antagonists & inhibitors | p38 Mitogen-Activated Protein Kinases - metabolism | Cystathionine gamma-Lyase - genetics | Nitric Oxide Synthase Type III - metabolism | Cystathionine gamma-Lyase - deficiency | Sulfides - pharmacology | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Aorta - drug effects | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Carrier Proteins - antagonists & inhibitors | Gene Expression Regulation | p38 Mitogen-Activated Protein Kinases - genetics | Nitric Oxide Synthase Type III - genetics | Mice, Knockout | Aorta - pathology | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Glycine - pharmacology | Mitogen-Activated Protein Kinase 3 - metabolism | Endothelium, Vascular - metabolism | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | MAP Kinase Kinase 4 - genetics | Endothelium, Vascular - pathology | Mice | Protein Kinase Inhibitors - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Medical research | Nitric oxide | Medicine, Experimental | Acetylcholine | Thioredoxin | Protein kinases | Endothelium | Index Medicus
Journal Article