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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2009, Volume 330, Issue 3, pp. 764 - 770
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 04/2017, Volume 71, pp. 30 - 54
[Display omitted] 1,2,3-Triazoles are important five-membered heterocyclic scaffold due to their extensive biological activities. This framework can be readily... 
1,3-Dipolar cycloaddition | Multicomponent reaction | 1,2,3-Triazole | Alkyne–azide coupling reaction | AZIDE-ALKYNE CYCLOADDITION | 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES | ONE-POT SYNTHESIS | CLICK CHEMISTRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DENGUE VIRUS-REPLICATION | CHEMISTRY, ORGANIC | Alkyne-azide coupling reaction | MOLECULAR DOCKING | METAL-FREE SYNTHESIS | BIOLOGICAL EVALUATION | IN-VITRO ACTIVITY | ANTIINFLAMMATORY DRUGS | Triazoles - chemistry | Anti-Infective Agents - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Drug Discovery - methods | Azides - chemistry | HIV Protease Inhibitors - pharmacology | Anti-Infective Agents - chemistry | Triazoles - chemical synthesis | Antineoplastic Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Click Chemistry - methods | Models, Molecular | HIV Protease Inhibitors - chemistry | Alkynes - chemistry | Cyclooxygenase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Anti-Infective Agents - chemical synthesis | Cycloaddition Reaction - methods | Cyclooxygenase Inhibitors - pharmacology | Triazoles - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Cyclooxygenase Inhibitors - chemical synthesis | Anti-Inflammatory Agents - chemical synthesis | HIV Protease Inhibitors - chemical synthesis | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Triazoles | COX-2 inhibitors | Protease inhibitors | Proteases
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 2015, Volume 172, Issue 6, pp. 1607 - 1619
Journal Article
Journal Article
Plant Cell Reports, ISSN 0721-7714, 05/2016, Volume 35, Issue 5, pp. 1155 - 1168
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2012, Volume 55, Issue 10, pp. 4837 - 4846
Novel monocyclic cyanoenones examined to date display unique features regarding chemical reactivity as Michael acceptors and biological potency. Remarkably, in... 
CHEMISTRY, MEDICINAL | NITRIC-OXIDE PRODUCTION | CDDO | ACTIVE INHIBITORS | IKK-BETA | URSANE TRITERPENOIDS | MOUSE MACROPHAGES | DIRECT INHIBITION | NF-KAPPA-B | OLEANANE | 2-CYANO-3,12-DIOXOOLEAN-1,9-DIEN-28-OIC ACID | Alkynes - chemical synthesis | Anticarcinogenic Agents - chemical synthesis | Nitriles - pharmacology | Apoptosis - drug effects | Oleanolic Acid - analogs & derivatives | Oleanolic Acid - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Nitriles - chemical synthesis | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Phenanthrenes - chemistry | Macrophages - secretion | I-kappa B Kinase - antagonists & inhibitors | Alkynes - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Anticarcinogenic Agents - pharmacology | Cytoprotection | Amides - pharmacology | Interleukin-1beta - secretion | Cell Line | Nitric Oxide - biosynthesis | Nitric Oxide - antagonists & inhibitors | Tumor Necrosis Factor-alpha - secretion | Thiophenes - pharmacology | Alkynes - chemistry | Macrophages - cytology | Phenanthrenes - pharmacology | NAD(P)H Dehydrogenase (Quinone) - biosynthesis | Animals | Anticarcinogenic Agents - chemistry | Lipopolysaccharides - pharmacology | Nitriles - chemistry | Oleanolic Acid - chemistry | Amides - chemistry | Cell Line, Tumor | Macrophages - drug effects | Mice | Thiophenes - chemistry
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2015, Volume 172, Issue 6, pp. 1505 - 1515
Journal Article
Biomacromolecules, ISSN 1525-7797, 10/2013, Volume 14, Issue 10, pp. 3581 - 3588
Injectable hydrogels are useful in biomedical applications. We have synthesized hyaluronic acids chemically modified with azide groups (HA–A) and cyclooctyne... 
DESIGN | POLYMER SCIENCE | DRUG-DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | CELL-ADHESION | BIOCOMPATIBLE HYDROGELS | MICHAEL ADDITION | PERITONEAL ADHESIONS | CYCLOADDITIONS | ACID HYDROGELS | DERIVATIVES | SCAFFOLD | Biocompatible Materials - metabolism | NIH 3T3 Cells | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Hyaluronoglucosaminidase - metabolism | Biocompatible Materials - chemistry | Cross-Linking Reagents - pharmacology | Hyaluronic Acid - pharmacology | Male | Structure-Activity Relationship | Azides - chemistry | Cross-Linking Reagents - chemical synthesis | Dose-Response Relationship, Drug | Injections, Subcutaneous | Alkynes - metabolism | Alkynes - pharmacology | Cyclooctanes - pharmacology | Hydrogel, Polyethylene Glycol Dimethacrylate - pharmacology | Molecular Structure | Azides - pharmacology | Azides - metabolism | Copper | Fibroblasts - metabolism | Hydrogel, Polyethylene Glycol Dimethacrylate - metabolism | Cell Survival - drug effects | Click Chemistry | Hyaluronic Acid - chemistry | Injections, Intraperitoneal | Cyclooctanes - metabolism | Alkynes - chemistry | Biocompatible Materials - pharmacology | Hyaluronoglucosaminidase - chemistry | Mice, Inbred ICR | Cross-Linking Reagents - metabolism | Animals | Cyclization | Fibroblasts - drug effects | Hyaluronic Acid - metabolism | Cyclooctanes - chemistry | Hydrogel, Polyethylene Glycol Dimethacrylate - chemical synthesis | Mice
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2013, Volume 720, Issue 1-3, pp. 276 - 285
Journal Article
Journal Article
Journal Article