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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2019, Volume 116, Issue 8, pp. 3294 - 3299
The parathyroid hormone (PTH) and its related peptide (PTHrP) activate PTH receptor (PTHR) signaling, but only the PTH sustains G -mediated adenosine... 
PTH recepto | Endosomal cAMP signaling | PTH | GPCR signaling | allosterism
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 06/2017, Volume 23, Issue 34, pp. 8286 - 8294
A salicylaldehyde derivative bearing four pyridine arms, 3,5‐bis(N,N‐bis(2‐pyridylmethyl)aminomethyl)‐2,4‐dihydroxybenzaldehyde (Hbpsal) as a “socket”, was... 
coordination modes | chiral auxiliaries | Schiff bases | Mannich bases | allosterism
Journal Article
ChemMedChem, ISSN 1860-7179, 08/2016, Volume 11, Issue 16, pp. 1669 - 1669
The front cover picture shows the heterodimeric structure of the HIV‐1 reverse transcriptase (RT) complexed with the RNA:DNA duplex. RT is a multifunctional... 
allosterism antiviral agents inhibitors medicinal chemistry ribonucleases
Journal Article
Neurochemistry International, ISSN 0197-0186, 07/2013, Volume 63, Issue 1, pp. 42 - 46
The molecular interaction between adenosine A and dopamine D receptors (A Rs and D Rs, respectively) within an oligomeric complex has been postulated to play a... 
Receptor-receptor allosterism | Antiparkinsonian drugs | Parkinson's disease
Journal Article
Pharmacological Research, ISSN 1043-6618, 07/2015, Volume 99, pp. 370 - 376
Cannabinoid pharmacology has proven nettlesome with issues of promiscuity a common theme among both agonists and antagonists. One recourse is to develop... 
Allosteric | Depolarization-induced suppression of excitation | Excitatory postsynaptic current | Allosterism | Orthosteric | Cannabinoid | Tetrahydrocannabinol
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2013, Volume 168, Issue 5, pp. 1101 - 1103
Journal Article
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 01/2019, Volume 37, Issue 1, pp. 36 - 47
Allostery is one of the most important features of proteins. It greatly contributes to the complexity of life, since it enables possibility of precise tuning... 
μ opioid receptor | probe dependence | molecular dynamics | GPCRs | allosterism
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 02/2019, Volume 25, Issue 11, pp. 2646 - 2646
DNA‐binding polyamides are molecules that hold great promise as regulators of gene expression. One of the challenges in their therapeutic development is... 
minor groove binder | pyrrole-imidazole polyamide | binding kinetics | NMR characterisation | allosterism
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 4637 - 14
Proper determination of agonist efficacy is essential in the assessment of agonist selectivity and signalling bias. Agonist efficacy is a relative term that is... 
AFFINITY | MULTIDISCIPLINARY SCIENCES | LOOP | PARAMETERS | RECEPTORS | ALLOSTERISM | BINDING | Acetylcholine receptors (muscarinic)
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 06/2018, Volume 24, Issue 34, p. n/a
Triple‐stranded metallohelicates possessing the internal guest binding cavities surrounded by the calix[4]arene units are depicted in the graphic. The... 
helicates | majority-rules effect | calixarenes | supramolecular chemistry | allosterism | Calixarenes | Chirality | Binding sites | Helicity | Molecular chains
Journal Article
Small GTPases, ISSN 2154-1248, 09/2017, pp. 1 - 8
In addition to the classical regulation of GTPase activity by effector proteins, investigating the variations in the amino acid sequence and structures of... 
TC10 | TCL | Rho GTPase | RhoJ | allosterism | Cdc42
Journal Article
Journal Article