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Current topics in medicinal chemistry, ISSN 1568-0266, 11/2016, Volume 16, Issue 27, pp. 3021 - 3032
Journal Article
Current drug discovery technologies, ISSN 1570-1638, 12/2015, Volume 12, Issue 4, pp. 193 - 204
NMR is becoming an important tool for developing new allosteric and allo-network drugs that bind to allosteric sites on enzymes, partially inhibiting them and... 
N HSQC | Allostery | NMR | CHESCA | Systems thinking
Journal Article
Current topics in medicinal chemistry, ISSN 1568-0266, 2017, Volume 17, Issue 1, pp. 4 - 15
The targeting of non-catalytic cysteine residues with small molecules is drawing increased attention from drug discovery scientists and chemical biologists.... 
Protein allostery | Structure-based design | Lead optimization | Non-catalytic cysteine | Protein dynamics | Chemical probes | Disulfide Tethering | Covalent drugs | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Molecular Structure | Catalysis | Cysteine - chemistry | Drug Discovery
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 09/2015, Volume 112, Issue 37, pp. 11553 - 11558
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 09/2018, Volume 99, Issue 6, pp. 1129 - 1143
Journal Article
Trends in biochemical sciences (Amsterdam. Regular ed.), ISSN 0968-0004, 11/2015, Volume 40, Issue 11, pp. 628 - 647
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 07/2018, Volume 61, Issue 14, pp. 6163 - 6177
Cancer cells rely on the chaperone heat shock protein 70 (Hsp70) for survival and proliferation. Recently, benzothiazole rhodacyanines have been shown to bind... 
Index Medicus | breast cancer | non-oncogene addiction | chaperone | structure-activity relationships | proteostasis | allostery
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 07/2011, Volume 108, Issue 30, pp. 12289 - 12294
Journal Article