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Neurobiology of Aging, ISSN 0197-4580, 2016, Volume 37, pp. 103 - 116
Abstract With increased histone deacetylase (HDAC) activity and histone hypoacetylation being implicated in neurodegeneration, HDAC inhibitors have been... 
Neurology | Internal Medicine | Histone deacetylase | Histone deacetylase inhibitor | Parkinson's disease | Neurodegeneration | K560 | Isoform-specific | MPTP | HDAC INHIBITORS | OXIDATIVE-STRESS | SUBEROYLANILIDE HYDROXAMIC ACID | 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE MOUSE MODEL | PROTECTS DOPAMINERGIC-NEURONS | VALPROIC ACID | ALPHA-SYNUCLEIN | NEUROSCIENCES | CELL-DEATH | GERIATRICS & GERONTOLOGY | IN-VIVO | GENE-TRANSCRIPTION | Neuroprotective Agents - therapeutic use | Diketopiperazines - administration & dosage | Gene Expression - drug effects | Humans | Histone Deacetylase 2 - physiology | Histone Deacetylase 1 - physiology | Parkinson Disease - drug therapy | Molecular Targeted Therapy | Benzamides - administration & dosage | Benzamides - therapeutic use | Neuroprotective Agents - pharmacology | Cell Death - genetics | Histone Deacetylase 1 - antagonists & inhibitors | Benzamides - pharmacology | Acetylation | Cell Death - drug effects | Drug Evaluation, Preclinical | Disease Models, Animal | Parkinson Disease - pathology | Administration, Oral | Diketopiperazines - therapeutic use | Histone Deacetylase 2 - antagonists & inhibitors | Isoenzymes | Enzyme Inhibitors - pharmacology | Diketopiperazines - pharmacology | Enzyme Inhibitors - therapeutic use | X-Linked Inhibitor of Apoptosis Protein - genetics | Animals | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Mice | Histones - metabolism | Parkinson Disease - etiology | Tumor proteins | Analysis | Index Medicus
Journal Article
Journal Article
GLIA, ISSN 0894-1491, 11/2017, Volume 65, Issue 11, pp. 1777 - 1793
Synaptic activity results in transient elevations in extracellular K+, clearance of which is critical for sustained function of the nervous system. The K+... 
expression pattern | NA,K-ATPASE | isoforms | NEUROLOGICAL DISORDERS | EXTRACELLULAR K | NEUROSCIENCES | isoform-pairing | FUNCTIONAL-PROPERTIES | NA+,K+-ATPASE ALPHA-SUBUNIT | K+ clearance | CENTRAL-NERVOUS-SYSTEM | astrocytes | RAT-BRAIN | BETA-SUBUNIT | EXPRESSION | IN-SITU
Journal Article
JOURNAL OF HYPERTENSION, ISSN 0263-6352, 09/2014, Volume 32, Issue 9, pp. 1842 - 1853
Objective: The progression from prehypertensive to hypertensive state in spontaneous hypertensive rats (SHRs) is accompanied by a significant increase in... 
MDCK CELLS | blood pressure regulation | proteomics | K+-ATPASE | ALPHA-SUBUNIT | SPONTANEOUSLY HYPERTENSIVE-RATS | TRAFFICKING | MEMBRANES | FUNCTIONAL-ROLE | BETA-SUBUNITS | Na-K-2Cl co-transporter type 2 | interacting proteins | PERIPHERAL VASCULAR DISEASE | beta 1-subunit of Na+-K+-ATPase | spontaneous hypertensive rats | hypertension | EXPRESSION | ASSOCIATION
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 11/2011, Volume 301, Issue 5, pp. H2147 - H2153
Journal Article
BMC NEUROSCIENCE, ISSN 1471-2202, 09/2017, Volume 18
Background: The Na+/K+-ATPases are transmembrane ion pumps important for maintenance of ion gradients across the plasma membrane that serve to support multiple... 
NUCLEAR | PROTEIN | NA,K-ATPASE | MOUSE | Spinal cord injury | Na+/K+-ATPase alpha isoform | CHEMOKINE MESSENGER-RNA | NEUROSCIENCES | Functional recovery | GLUTAMATE TRANSPORTERS | CYCLIC-GMP | SODIUM-PUMP | AGE-RELATED-CHANGES | Reduced lesion volume | SUBUNIT
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 12/2005, Volume 46, Issue 12, pp. 2657 - 2666
Journal Article
by Xue, ZX and Li, BM and Gu, L and Hu, XL and Li, M and Butterworth, RF and Peng, LA
NEUROCHEMISTRY INTERNATIONAL, ISSN 0197-0186, 11/2010, Volume 57, Issue 4, pp. 395 - 403
In mouse astrocyte cultures identical to those used in the present study ammonia increases the production of ouabain-like compounds and Na, K-ATPase activity... 
MOUSE ASTROCYTES | Astrocytes | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAT ASTROCYTES | BENZODIAZEPINE-RECEPTORS | TYROSINE KINASES | Gene expression | NEUROSCIENCES | Ammonia | MITOCHONDRIAL PERMEABILITY TRANSITION | OUABAIN | EGF receptor | Ouabain-like compounds | CULTURED ASTROCYTES | HEPATIC-ENCEPHALOPATHY | UP-REGULATION | ERK PHOSPHORYLATION | Na, K-ATPase alpha isoform
Journal Article
AMERICAN JOURNAL OF HYPERTENSION, ISSN 0895-7061, 12/2010, Volume 23, Issue 12, pp. 1279 - 1285
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 03/2008, Volume 294, Issue 3, pp. H1407 - H1416
Journal Article
by Wan, GQ and Zhou, LH and Lim, QE and Wong, YH and Too, HP
CELLULAR SIGNALLING, ISSN 0898-6568, 11/2011, Volume 23, Issue 11, pp. 1727 - 1737
Cyclic AMP (cAMP) and neurotrophic factors are known to interact closely to promote neurite outgrowth and neuronal regeneration. Ghat cell line-derived... 
PARASYMPATHETIC GANGLION NEURONS | Biphasic ERK1/2 activation | NEUROTROPHIC FACTOR | PKA | GDNF FAMILY LIGANDS | AXONAL REGENERATION | Neurturin | cAMP | SENSORY NEURONS | NERVE GROWTH-FACTOR | CELL BIOLOGY | GFR alpha 2 | ADENOSINE-MONOPHOSPHATE | SUSTAINED ACTIVATION | SPINAL-CORD-INJURY | PC12 CELLS | Neurite outgrowth
Journal Article
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 01/2000, Volume 156, Issue 1, pp. 253 - 268
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease of the kidney, characterized by cystic enlargement of renal tubules, aberrant... 
CATALYTIC SUBUNIT | SEQUENCE-ANALYSIS | (NA+ + K+)-ATPASE | DIFFERENTIAL EXPRESSION | ADHESION MOLECULE | ALPHA-SUBUNIT | INTRACELLULAR-TRANSPORT | MURINE NA,K-ATPASE | TUBULE NA,K-ATPASE POLARITY | PATHOLOGY | ENZYMATIC-PROPERTIES
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2004, Volume 91, Issue 5, pp. 1104 - 1115
Octopamine regulates essential processes in nematodes; however, little is known about the physiological role of its precursor, tyramine. In the present study,... 
foraging | pertussis toxin | nematode | pharyngeal pumping | alternative‐splicing | tyramine receptors | Nematode | Tyramine receptors | Foraging | Alternative-splicing | Pertussis toxin | Pharyngeal pumping | 3RD INTRACELLULAR LOOP | NERVOUS-SYSTEM | DNA-BINDING | DROSOPHILA-MELANOGASTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | G-PROTEINS | NEUROSCIENCES | LOCUSTA-MIGRATORIA-MIGRATORIOIDES | CYTOPLASMIC LOOP | alternative-splicing | OCTOPAMINE RECEPTOR | EXPRESSION | BETA-ADRENERGIC RECEPTOR | Receptors, Biogenic Amine - physiology | Calcium - metabolism | Embryo, Mammalian | Nose - physiology | Humans | Receptors, Biogenic Amine - genetics | Cercopithecus aethiops | Octopamine - pharmacology | Serotonin - pharmacology | Receptors, Biogenic Amine - chemistry | Behavior, Animal | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Caenorhabditis elegans - physiology | RNA, Messenger - biosynthesis | Extracellular Space - metabolism | Drug Interactions | Transfection | Time Factors | Gene Expression - physiology | Reverse Transcriptase Polymerase Chain Reaction - methods | Cloning, Molecular - methods | Radioligand Assay - methods | Phosphatidylinositols - metabolism | Cell Membrane - metabolism | Pharynx - physiology | Cyclic AMP - metabolism | Cell Membrane - drug effects | Nose - drug effects | Pertussis Toxin - pharmacology | Tyramine - pharmacology | Amino Acid Sequence | Cell Line | Green Fluorescent Proteins - metabolism | Biogenic Monoamines - pharmacokinetics | Lysergic Acid Diethylamide - pharmacokinetics | Models, Molecular | Feeding Behavior - physiology | Protein Isoforms - physiology | Phenotype | Animals | DNA, Recombinant | Embryo, Nonmammalian | Receptors, Biogenic Amine - metabolism | Animals, Genetically Modified - physiology | Adrenergic Uptake Inhibitors - pharmacology | Adrenergic alpha-Agonists - pharmacology | Tritium - pharmacokinetics | Index Medicus
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 11/2015, Volume 112, Issue 44, pp. 13723 - 13728
The ciliary epithelium in the eye consists of pigmented epithelial cells that express the alpha 1 beta 1 isoform of Na,K-ATPase and nonpigmented epithelial... 
GLYCOSIDES | COMPLEX | intraocular pressure | K+-ATPASE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | Na/K-ATPase | alpha 2 beta 3 isoform | DIGITALIS | digoxin derivatives | TRANSPORT | OUABAIN | NONPIGMENTED CILIARY EPITHELIUM | BINDING-SITE | EXPRESSION
Journal Article