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PLoS Pathogens, ISSN 1553-7366, 10/2011, Volume 7, Issue 10, p. e1002322
Chikungunya virus (CHIKV) is a re-emerging alphavirus that has caused significant disease in the Indian Ocean region since 2005. During this outbreak, in... 
ACTIVATION | INTERFERON-STIMULATED GENE-15 | REUNION ISLAND | UBIQUITIN-LIKE PROTEIN | MICROBIOLOGY | IDENTIFICATION | ANTIVIRAL MOLECULE | RESPONSES | ENZYME | VIROLOGY | EPIDEMIC | PARASITOLOGY | AGE | Alphavirus Infections - diagnosis | Animals, Newborn | Chikungunya Fever | Ubiquitins - immunology | Cytokines - metabolism | Humans | Mice, Inbred C57BL | Ubiquitin-Activating Enzymes - immunology | Alphavirus Infections - immunology | Interferon Type I - immunology | Ubiquitin-Activating Enzymes - metabolism | Animals | Recombination, Genetic | Alphavirus Infections - metabolism | Interferon Type I - metabolism | Protein Binding | Chikungunya virus - physiology | Mice | Retrospective Studies | Ubiquitins - metabolism | Chikungunya virus - pathogenicity | Cytokines - immunology | Disease Models, Animal | Physiological aspects | Development and progression | Interferon | Chikungunya fever | Immune response | Research | Proteins | Infections | Viral infections | Immune system | Alphavirus Infections/metabolism | Ubiquitin-Activating Enzymes/immunology | Cytokines/immunology | Life Sciences | Alphavirus Infections/immunology | Immunology | Alphavirus Infections/diagnosis | Chikungunya virus/pathogenicity | Interferon Type I/immunology | Ubiquitins/metabolism | Cytokines/metabolism | Chikungunya virus/physiology | Interferon Type I/metabolism | Ubiquitins/immunology | Ubiquitin-Activating Enzymes/metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2016, Volume 113, Issue 8, pp. 2241 - 2246
The 2′,5′-oligoadenylate (2-5A) synthetase (OAS)–RNase L system is an IFN-induced antiviral pathway. RNase L activity depends on 2-5A, synthesized by OAS.... 
2-5A | Oligoadenylate synthetase 3 | Antiviral response | Type I interferon | Ribonuclease L | ENCEPHALOMYOCARDITIS VIRUS | L PATHWAY | HUMAN 2',5'-OLIGOADENYLATE SYNTHETASE | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | HUMAN OLIGOADENYLATE SYNTHETASE | CRISPR-CAS9 SYSTEM | RIG-I | oligoadenylate synthetase 3 | VACCINIA VIRUS | antiviral response | type I interferon | MURINE CORONAVIRUS | ribonuclease L | ANTIVIRAL ACTIVITY | Endoribonucleases - genetics | Humans | 2',5'-Oligoadenylate Synthetase - antagonists & inhibitors | Endoribonucleases - antagonists & inhibitors | RNA, Ribosomal - genetics | Alphavirus Infections - genetics | Sindbis Virus | RNA, Viral - genetics | Alphavirus Infections - metabolism | RNA, Viral - metabolism | Virus Diseases - genetics | Vaccinia - metabolism | 2',5'-Oligoadenylate Synthetase - metabolism | Cell Line | Influenza, Human - metabolism | West Nile Fever - genetics | Endoribonucleases - metabolism | RNA, Ribosomal - metabolism | West Nile Fever - metabolism | Virus Diseases - metabolism | Gene Knockout Techniques | Vaccinia - genetics | 2',5'-Oligoadenylate Synthetase - genetics | Models, Biological | Influenza, Human - genetics | CRISPR-Cas Systems | Enzyme Activation | Genetic aspects | Interferon | Host-virus relationships | Gene expression | Observations | Health aspects | RNA polymerases | Biological Sciences
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2013, Volume 9, Issue 9, p. e1003619
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2013, Volume 9, Issue 10, p. e1003678
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2008, Volume 4, Issue 2, pp. e29 - e29
Journal Article