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Seminars in immunopathology, ISSN 1863-2300, 2011, Volume 34, Issue 1, pp. 43 - 62
The interaction of coagulation factors with the perivascular environment affects the development of disease in ways that extend beyond their traditional roles in the acute hemostatic cascade... 
Autoimmunity | Complement receptor 3 | Multiple sclerosis | Stroke | Alzheimer’s disease | Internal Medicine | Macrophages | Blood brain barrier | Inflammatory disease | Microglia | Biomedicine | Immunology | Rheumatoid arthritis | CD11b/CD18 | Atherosclerosis | Plasminogen | Anticoagulant therapy | Alzheimer's disease | ALZHEIMERS-DISEASE | IMMUNOLOGY | PATHOLOGY | GAMMA-C-DOMAIN | BINDING-SITE | CENTRAL-NERVOUS-SYSTEM | MULTIPLE-SCLEROSIS LESIONS | CRYSTAL-STRUCTURE | BLOOD-BRAIN-BARRIER | INTEGRIN ALPHA(M)BETA | PROTEASE-ACTIVATED RECEPTORS | PERIPHERAL ARTERIAL-DISEASE | Colitis - genetics | Humans | Brain Injuries - metabolism | Arthritis, Rheumatoid - metabolism | Bacterial Infections - genetics | Inflammation - metabolism | Blood Coagulation - immunology | Muscular Dystrophy, Duchenne - immunology | Alzheimer Disease - immunology | Fibrinogen - immunology | Thromboplastin - immunology | Pulmonary Fibrosis - immunology | Vascular Diseases - genetics | Brain Injuries - genetics | Thrombin - genetics | Kidney Diseases - immunology | Arthritis, Rheumatoid - genetics | Neoplasms - immunology | Colitis - metabolism | Muscular Dystrophy, Duchenne - genetics | Bacterial Infections - metabolism | Neoplasms - metabolism | Pulmonary Fibrosis - genetics | Spinal Cord Injuries - genetics | Kidney Diseases - genetics | Stroke - genetics | Brain Injuries - immunology | Neoplasms - genetics | Bacterial Infections - immunology | Pulmonary Fibrosis - metabolism | Colitis - immunology | Thrombin - immunology | Stroke - immunology | Kidney Diseases - metabolism | Multiple Sclerosis - metabolism | Vascular Diseases - immunology | Spinal Cord Injuries - metabolism | Multiple Sclerosis - genetics | Inflammation - immunology | Fibrinogen - genetics | Stroke - metabolism | Animals | Thromboplastin - genetics | Alzheimer Disease - metabolism | Fibrinogen - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Blood Coagulation - genetics | Spinal Cord Injuries - immunology | Muscular Dystrophy, Duchenne - metabolism | Thrombin - metabolism | Thromboplastin - metabolism | Alzheimer Disease - genetics | Arthritis, Rheumatoid - immunology | Vascular Diseases - metabolism | Nervous system diseases | Bacterial infections | Oncology, Experimental | Thrombin | Inflammation | Anticoagulants (Medicine) | Research | Rheumatoid factor | Fibrin | Fibrinogen | Genetic research | Colitis | Cancer | Traumatic brain injury | Coagulation | Tissue factor | hemostasis | Spinal cord injury | Inflammatory diseases | Kidney | Signal transduction | Duchenne's muscular dystrophy | Neurodegenerative diseases | Therapeutic applications | Thrombosis | Coagulation factors | Infection | Molecular modelling | Fibrosis | Brain injury
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2014, Volume 344, Issue 6183, pp. 519 - 523
Journal Article
Nature (London), ISSN 1476-4687, 2015, Volume 518, Issue 7539, pp. 365 - 369
Alzheimer's disease (AD) is a severe(1) age-related neurodegenerative disorder characterized by accumulation of amyloid-beta plaques and neurofibrillary tangles, synaptic and neuronal loss, and cognitive decline... 
TRANSCRIPTION FACTORS | ELEMENTS | ACTIVATION | DATABASE | MICROGLIA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | BINDING | DIFFERENTIAL EXPRESSION ANALYSIS | DISCOVERY | ENCODE | Genetic research | Epigenetic inheritance | Genetic aspects | Research | Neurological research | Alzheimer's disease | Proteins | Transcription factors | Immunology | Ontology | Neurodegeneration | Cell cycle | Gene loci | Gene expression | Alzheimers disease | Binding sites
Journal Article
PLoS genetics, ISSN 1553-7404, 2011, Volume 7, Issue 2, p. e1001308
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 11, p. e50976
Journal Article
by Hollingworth, Paul and Harold, Denise and Sims, Rebecca and Gerrish, Amy and Lambert, Jean-Charles and Carrasquillo, Minerva M and Abraham, Richard and Hamshere, Marian L and Pahwa, Jaspreet Singh and Moskvina, Valentina and Dowzell, Kimberley and Jones, Nicola and Stretton, Alexandra and Thomas, Charlene and Richards, Alex and Ivanov, Dobril and Widdowson, Caroline and Chapman, Jade and Lovestone, Simon and Powell, John and Proitsi, Petroula and Lupton, Michelle K and Brayne, Carol and Rubinsztein, David C and Gill, Michael and Lawlor, Brian and Lynch, Aoibhinn and Brown, Kristelle S and Passmore, Peter A and Craig, David and McGuinness, Bernadette and Todd, Stephen and Holmes, Clive and Mann, David and Smith, A David and Beaumont, Helen and Warden, Donald and Wilcock, Gordon and Love, Seth and Kehoe, Patrick G and Hooper, Nigel M and Vardy, Emma R L C and Hardy, John and Mead, Simon and Fox, Nick C and Rossor, Martin and Collinge, John and Maier, Wolfgang and Jessen, Frank and Rüther, Eckart and Schürmann, Britta and Heun, Reiner and Kölsch, Heike and van den Bussche, Hendrik and Heuser, Isabella and Kornhuber, Johannes and Wiltfang, Jens and Dichgans, Martin and Frölich, Lutz and Hampel, Harald and Gallacher, John and Hüll, Michael and Rujescu, Dan and Giegling, Ina and Goate, Alison M and Kauwe, John S K and Cruchaga, Carlos and Nowotny, Petra and Morris, John C and Mayo, Kevin and Sleegers, Kristel and Bettens, Karolien and Engelborghs, Sebastiaan and De Deyn, Peter P and Van Broeckhoven, Christine and Livingston, Gill and Bass, Nicholas J and Gurling, Hugh and McQuillin, Andrew and Gwilliam, Rhian and Deloukas, Panagiotis and Al-Chalabi, Ammar and Shaw, Christopher E and Tsolaki, Magda and Singleton, Andrew B and Guerreiro, Rita and Mühleisen, Thomas W and Nöthen, Markus M and Moebus, Susanne and Jöckel, Karl-Heinz and Klopp, Norman and Wichmann, H-Erich and Pankratz, V Shane and Sando, Sigrid B and Aasly, Jan O and Barcikowska, Maria and Wszolek, Zbigniew K and Dickson, Dennis W and Graff-Radford, Neill R and Petersen, Ronald C and ... and the Alzheimer's Disease Neuroimaging Initiative and EADI1 consortium and CHARGE consortium and Alzheimer's Dis Neuroimaging and EADI1 Consortium and CHARGE Consortium and Alzheimer's Disease Neuroimaging Initiative
Nature genetics, ISSN 1546-1718, 2011, Volume 43, Issue 5, pp. 429 - 435
Journal Article
Molecular neurodegeneration, ISSN 1750-1326, 2017, Volume 12, Issue 1, pp. 43 - 12
Alzheimer's disease (AD) is a highly heritable complex disease with