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Science, ISSN 0036-8075, 05/2016, Volume 352, Issue 6286, pp. 712 - 716
Journal Article
Nature, ISSN 0028-0836, 04/2018, Volume 556, Issue 7701, pp. 332 - 338
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2013, Volume 190, Issue 5, pp. 2241 - 2251
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 24 - 24
Neuroinflammation caused by local deposits of A beta(42) in the brain is key for the pathogenesis and progression of Alzheimer's disease. However, inflammation... 
STROKE | SYSTEM | IMMUNE-RESPONSE | ENERGY HOMEOSTASIS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | NEURODEGENERATION | MECHANISMS | MODEL | BRAIN | COMMUNICATION | Antimicrobial Cationic Peptides - immunology | Alzheimer Disease - complications | Brain - microbiology | Drosophila melanogaster - immunology | Hemocytes - immunology | Humans | Tumor Necrosis Factor-alpha - genetics | MAP Kinase Kinase 4 - immunology | Drosophila Proteins - immunology | Dysbiosis - microbiology | Enterobacteriaceae Infections - complications | Alzheimer Disease - pathology | Cell Movement - immunology | Enterobacteriaceae Infections - immunology | Hemocytes - pathology | Dysbiosis - immunology | Gastrointestinal Tract - immunology | Enterobacteriaceae - immunology | Leukocyte Reduction Procedures | Amyloid beta-Peptides - genetics | Peptide Fragments - immunology | Tumor Necrosis Factor-alpha - immunology | Hemocytes - microbiology | Alzheimer Disease - immunology | Antimicrobial Cationic Peptides - genetics | Peptide Fragments - genetics | Enterobacteriaceae - growth & development | Disease Models, Animal | Alzheimer Disease - microbiology | Microbiota - immunology | Signal Transduction | Enterobacteriaceae Infections - microbiology | Gene Expression Regulation | Gastrointestinal Tract - microbiology | Enterobacteriaceae Infections - pathology | Dysbiosis - complications | Disease Progression | Drosophila melanogaster - microbiology | Animals | Brain - pathology | MAP Kinase Kinase 4 - genetics | Amyloid beta-Peptides - immunology | Drosophila Proteins - genetics | Dysbiosis - pathology | Brain - immunology | Index Medicus
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 566 - 581.e9
Microglia play a pivotal role in the maintenance of brain homeostasis but lose homeostatic function during neurodegenerative disorders. We identified a... 
Alzheimer’s disease | multiple sclerosis | transcriptional regulation | neurodegeneration | TREM2 | APOE | amyotrophic lateral sclerosis | microglia | Alzheimer's disease | GENE-EXPRESSION SIGNATURE | ACTIVATION | MULTIPLE-SCLEROSIS | ALZHEIMERS-DISEASE | MOUSE MODEL | MACROPHAGE | MICE | IMMUNOLOGY | DEFICIENCY | APOLIPOPROTEIN-E | CELL-DEATH | Microglia - metabolism | Apolipoproteins E - deficiency | Membrane Glycoproteins - metabolism | Humans | Cerebral Cortex - pathology | Transcriptome | Apoptosis - genetics | Monocytes - metabolism | Gene Expression Profiling | Monocytes - immunology | Phagocytosis - genetics | Neurodegenerative Diseases - immunology | Apolipoproteins E - metabolism | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Microglia - immunology | Superoxide Dismutase-1 - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Neurons - metabolism | Disease Models, Animal | Gene Targeting | Plaque, Amyloid - pathology | Signal Transduction | Gene Expression Regulation | Phagocytosis - immunology | Immune Tolerance | Mice, Transgenic | Neurodegenerative Diseases - genetics | Neurodegenerative Diseases - metabolism | Mice, Knockout | Encephalomyelitis, Autoimmune, Experimental | Phenotype | Animals | Apoptosis - immunology | Apolipoproteins E - genetics | Alzheimer Disease - metabolism | Superoxide Dismutase-1 - genetics | Plaque, Amyloid - metabolism | Mice | Alzheimer Disease - genetics | Transforming Growth Factor beta - metabolism | Receptors, Immunologic - metabolism | Cluster Analysis | Nervous system diseases | Multiple sclerosis | Neurons | Analysis | Amyotrophic lateral sclerosis | Genetic aspects | Genetic transcription | Apolipoproteins | Brain | Animal models | Disease | Transcription | Genes | Homeostasis | Sclerosis | Proteins | Restoration | Neurodegeneration | Apolipoprotein E | Rodents | Plaques | Myeloid cells | Neurodegenerative diseases | Microglia | Neurological diseases | Molecular modelling | β-Amyloid | Phagocytosis | Apoptosis | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2009, Volume 119, Issue 1, pp. 182 - 192
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2016, Volume 22, Issue 2, pp. 135 - 137
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/2018, Volume 215, Issue 4, pp. 1047 - 1058
One of the hallmarks of Alzheimer's disease is the presence of extracellular diffuse and fibrillar plaques predominantly consisting of the amyloid-beta (A... 
MEDICINE, RESEARCH & EXPERIMENTAL | CLEARANCE | BETA-PEPTIDE DEPOSITION | MOUSE MODEL | IN-VIVO | TREM2 VARIANTS | IMMUNOLOGY | ALZHEIMERS-DISEASE MODEL | E-DEFICIENT MICE | BRAIN | APOLIPOPROTEIN-E | TRANSGENIC MICE | Microglia - metabolism | Humans | Amyloid beta-Protein Precursor - immunology | Apolipoproteins E - metabolism | Alzheimer Disease - pathology | Brain - metabolism | Microglia - immunology | Amyloid - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Microglia - pathology | Alzheimer Disease - immunology | Plaque, Amyloid - immunology | Disease Models, Animal | Plaque, Amyloid - pathology | Mice, Transgenic | Immunity, Innate - immunology | Animals | Apolipoproteins E - immunology | Alzheimer Disease - metabolism | Amyloid - immunology | Brain - pathology | Amyloid beta-Peptides - immunology | Plaque, Amyloid - metabolism | Mice | Brain - immunology | Neuroimaging | Brain | Toxicity | Immune clearance | Fluorescence | Reduction | Neurotoxicity | Apolipoprotein E | Neurodegeneration | Rodents | Deposition | Plaques | Fluoroscopic imaging | Immune response | Neurodegenerative diseases | Transgenic mice | Metabolism | Gene expression | Apolipoproteins | Neurological diseases | Immune systems | Pathology | Axons | β-Amyloid | 306 | 311 | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2007, Volume 30, Issue 5, pp. 759 - 768
Abstract In Alzheimer's disease (AD), Parkinson's disease (PD), dementia with Lewy bodies (DLB) and amyotrophic lateral sclerosis (ALS), neuroinflammatory... 
Neurology | Internal Medicine | Lewy bodies dementia | Brain aging | Parkinson's disease | Neurodegenerative diseases | Toll-like receptors | Innate immunity | Amyotrophic lateral sclerosis | CD14 | Alzheimer's disease | ALZHEIMERS-DISEASE | LPS RECEPTOR | AMYOTROPHIC-LATERAL-SCLEROSIS | ALPHA-SYNUCLEIN | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | HEAT-SHOCK PROTEINS | TRANSGENIC-MOUSE MODEL | CELL UPTAKE | CENTRAL-NERVOUS-SYSTEM | PARKINSONS-DISEASE | Amyotrophic Lateral Sclerosis - physiopathology | Lewy Body Disease - immunology | Species Specificity | Extracellular Fluid - immunology | Humans | Male | Neurodegenerative Diseases - immunology | Lipopolysaccharide Receptors - analysis | Lipopolysaccharide Receptors - metabolism | Brain - metabolism | Lewy Body Disease - genetics | Encephalitis - physiopathology | Immunity, Innate - physiology | Encephalitis - metabolism | Female | Toll-Like Receptors - metabolism | Alzheimer Disease - immunology | Disease Models, Animal | Biomarkers - metabolism | Amyotrophic Lateral Sclerosis - immunology | Alzheimer Disease - physiopathology | Parkinson Disease - immunology | Amyotrophic Lateral Sclerosis - genetics | Brain - physiopathology | Mice, Inbred C57BL | Biomarkers - analysis | Encephalitis - immunology | Mice, Transgenic | Neurodegenerative Diseases - genetics | Up-Regulation - genetics | Parkinson Disease - genetics | Parkinson Disease - physiopathology | Toll-Like Receptors - analysis | Animals | Neurodegenerative Diseases - physiopathology | Up-Regulation - immunology | Mice | Alzheimer Disease - genetics | Brain - immunology | Lewy Body Disease - physiopathology | Proteins | Neurons | Analysis | Nervous system | Degeneration | Epidemiology | Brain diseases | Index Medicus
Journal Article