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Publication DateMolecular and cellular endocrinology, ISSN 0303-7207, 01/2013, Volume 365, Issue 1, pp. 11 - 16
Asymmetric dimethylarginine | Nitric oxide synthase | Estrogen | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Endothelium, Vascular - cytology | Receptors, Estrogen - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Endothelium, Vascular - drug effects | Estrogen Antagonists - pharmacology | Isoenzymes - chemistry | Receptors, G-Protein-Coupled - agonists | Estradiol - agonists | Arginine - analogs & derivatives | Nitric Oxide Synthase Type III - chemistry | Estrogen Receptor beta - metabolism | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Arginine - antagonists & inhibitors | Isoenzymes - metabolism | Estrogen Receptor alpha - metabolism | Nitric Oxide Synthase Type III - metabolism | Protein Stability | Estrogen Receptor beta - antagonists & inhibitors | Repressor Proteins - metabolism | Amidohydrolases - metabolism | Estradiol - metabolism | Receptors, Estrogen - agonists | Lipoproteins, LDL - adverse effects | Nitric Oxide - antagonists & inhibitors | Cells, Cultured | Receptors, Estrogen - antagonists & inhibitors | Amidohydrolases - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Amidohydrolases - chemistry | Blotting, Western | Nitric Oxide - agonists | Nitric Oxide Synthase Type III - antagonists & inhibitors | Protein-Arginine N-Methyltransferases - metabolism | Estradiol - chemistry | Lipoproteins, LDL - antagonists & inhibitors | Endothelium, Vascular - metabolism | Umbilical Arteries - cytology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Arginine - adverse effects | Estrogens, Non-Steroidal - pharmacology | Nitric Oxide - metabolism | Arginine - metabolism | Isoenzymes - antagonists & inhibitors | Physiological aspects | Phenols | Estradiol | Nitric oxide | Endothelium | Index Medicus | Human | Proteins | Receptors | Inhibitors | Pathways | Estrogens | Exposure | Endothelial cells
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Loading RightsNeuropsychopharmacology (New York, N.Y.), ISSN 0893-133X, 08/2013, Volume 38, Issue 9, pp. 1816 - 1824
Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Psychology. Psychoanalysis. Psychiatry | Psychoses | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Schizophrenia | Biological and medical sciences | Medical sciences | Endocannabinoids - metabolism | Phencyclidine - pharmacology | Amygdala - drug effects | Male | Piperidines - antagonists & inhibitors | Cannabinoid Receptor Agonists - pharmacology | Receptor, Cannabinoid, CB1 - physiology | Dose-Response Relationship, Drug | Arachidonic Acids - metabolism | Endocannabinoids - physiology | Prefrontal Cortex - drug effects | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Schizophrenia - physiopathology | Social Behavior | Cannabinoid Receptor Antagonists - pharmacology | Benzamides - pharmacology | Cyclohexanols - pharmacology | Quinazolinones - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Phencyclidine - antagonists & inhibitors | Amygdala - metabolism | Receptor, Cholecystokinin B - antagonists & inhibitors | Rats | Amidohydrolases - antagonists & inhibitors | Polyunsaturated Alkamides - metabolism | Animals | Prefrontal Cortex - metabolism | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Pyrazoles - antagonists & inhibitors | Index Medicus | endocannabinoid | animal models | negative symptoms | cholecystokinin | antipsychotics | cannabinoids | social interaction | Neuropharmacology | schizophrenia | PCP | Original
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Loading RightsNature neuroscience, ISSN 1097-6256, 09/2010, Volume 13, Issue 9, pp. 1113 - 1119
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cannabinoid Receptor Modulators - metabolism | Analgesics - pharmacology | Monoacylglycerol Lipases - antagonists & inhibitors | Neuronal Plasticity - drug effects | Male | Benzodioxoles - administration & dosage | Pain - metabolism | Brain - physiology | Monoacylglycerol Lipases - genetics | Enzyme Inhibitors - administration & dosage | Monoacylglycerol Lipases - metabolism | Neuronal Plasticity - physiology | Piperidines - pharmacology | Pain - drug therapy | Female | Models, Animal | Endocannabinoids | Amidohydrolases - metabolism | Synapses - drug effects | Piperidines - administration & dosage | Synapses - physiology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Analgesics - administration & dosage | Amidohydrolases - antagonists & inhibitors | Mice, Transgenic | Mice, Knockout | Brain - drug effects | Receptor, Cannabinoid, CB1 - metabolism | Animals | Cannabinoid Receptor Modulators - antagonists & inhibitors | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Benzodioxoles - pharmacology | Complications and side effects | Cannabinoids | Drug tolerance | Physiological aspects | Neuropharmacology | Research | Properties | Drug receptors | Index Medicus
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Loading RightsBritish journal of pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 4, pp. 794 - 807
Abn‐CBD | cannabidiol | endocannabinoid | CB1‐independent mechanism | PF750 | carbamate | off‐target | MAPK | dopamine | tyrosine hydroxylase promoter | off-target | Abn-CBD | CB1-independent mechanism | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Endocannabinoids - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Tyrosine 3-Monooxygenase - metabolism | Cannabidiol - antagonists & inhibitors | Hippocampus - drug effects | Promoter Regions, Genetic - drug effects | Corpus Striatum - metabolism | Receptor, Cannabinoid, CB1 - agonists | Dopaminergic Neurons - metabolism | Cannabinoid Receptor Antagonists - pharmacology | Dopaminergic Neurons - drug effects | Hippocampus - enzymology | Animals, Outbred Strains | Antidepressive Agents - pharmacology | Benzamides - pharmacology | Corpus Striatum - enzymology | Carbamates - pharmacology | Amidohydrolases - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Anti-Anxiety Agents - pharmacology | Tyrosine 3-Monooxygenase - antagonists & inhibitors | Amidohydrolases - antagonists & inhibitors | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Tyrosine 3-Monooxygenase - genetics | Dopaminergic Neurons - enzymology | Animals | Peroxisome Proliferator-Activated Receptors - metabolism | Cell Line, Tumor | Corpus Striatum - drug effects | Genes, Reporter - drug effects | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Cannabidiol - metabolism | Endocannabinoids - antagonists & inhibitors | Tyrosine | RNA | Physiological aspects | Phenols | Genetic research | Carbamates | Hydroxylases | Lipase | Fatty acids | Index Medicus | Cannabinoids 2012, Part Two | Themed Section
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Loading RightsThe Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 10/2011, Volume 339, Issue 1, pp. 173 - 185
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Brain Chemistry - drug effects | Cannabinoid Receptor Modulators - metabolism | Arachidonic Acid - metabolism | Electric Stimulation | Monoacylglycerol Lipases - antagonists & inhibitors | Ileum - metabolism | Substance Withdrawal Syndrome - drug therapy | Diarrhea - prevention & control | Male | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Weight Loss - drug effects | Monoacylglycerol Lipases - genetics | Ileum - drug effects | Piperidines - pharmacology | Behavior, Animal - drug effects | Dronabinol - pharmacology | Endocannabinoids | Amidohydrolases - genetics | Mice, Inbred C57BL | Amidohydrolases - antagonists & inhibitors | Morphine Dependence - complications | Mice, Inbred ICR | Mice, Knockout | Hydrolysis | Animals | Muscle Contraction - drug effects | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Mice | Pyridines - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Substance Withdrawal Syndrome - psychology | Benzodioxoles - pharmacology | Prostaglandins - metabolism | Index Medicus
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Full Text
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis
Biochimica et biophysica acta. Molecular and cell biology of lipids, ISSN 1388-1981, 2006, Volume 1761, Issue 2, pp. 205 - 212
2-Arachidonoylglycerol | Inhibitor | Cannabinoid | Lipase | Diacylglycerol | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Lipoprotein Lipase - antagonists & inhibitors | Liver - enzymology | Monoacylglycerol Lipases - antagonists & inhibitors | Humans | Cercopithecus aethiops | Lactones - pharmacology | Monoacylglycerol Lipases - genetics | Lipase - antagonists & inhibitors | Drug Design | Molecular Structure | Oleic Acids - pharmacology | Drug Evaluation, Preclinical | Endocannabinoids | Recombinant Proteins - antagonists & inhibitors | Cannabinoid Receptor Modulators - biosynthesis | Lipoprotein Lipase - genetics | Rats | Amidohydrolases - antagonists & inhibitors | Recombinant Proteins - genetics | Phospholipase D - antagonists & inhibitors | Animals | Cannabinoid Receptor Modulators - antagonists & inhibitors | Oleic Acids - chemical synthesis | In Vitro Techniques | COS Cells | Oleic Acids - chemistry | Glycerin | Weight reducing preparations | Phosphatidylinositol | Organic solvents | Oleic acid | Phosphonates | Physiological aspects | Glycerol | Triglycerides | Phospholipases | Cyclohexanol
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Loading RightsNeuropsychopharmacology (New York, N.Y.), ISSN 0893-133X, 10/2014, Volume 39, Issue 11, pp. 2529 - 2537
Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Memory - drug effects | Fear - drug effects | Male | Auditory Perception - physiology | Fear - physiology | Piperidines - pharmacology | Basolateral Nuclear Complex - physiology | Cannabinoid Receptor Antagonists - pharmacology | Benzamides - pharmacology | Basolateral Nuclear Complex - drug effects | Carbamates - pharmacology | GABA-A Receptor Antagonists - pharmacology | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Auditory Perception - drug effects | Enzyme Inhibitors - pharmacology | Rats | Amidohydrolases - antagonists & inhibitors | Bicuculline - pharmacology | Receptor, Cannabinoid, CB1 - metabolism | Animals | Conditioning, Classical | Receptors, GABA-A - metabolism | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Electroshock | Memory - physiology | Index Medicus | Original
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Loading RightsNature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 2384 - 2384
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Intestines - drug effects | Intestinal Mucosa - metabolism | Obesity - drug therapy | Receptors, Cytoplasmic and Nuclear - deficiency | Taurocholic Acid - metabolism | Intestinal Absorption - drug effects | Microbiota - drug effects | Diet, High-Fat - adverse effects | Male | Spin Labels | Obesity - microbiology | Taurocholic Acid - agonists | Amidohydrolases - biosynthesis | Cyclic N-Oxides - pharmacology | Lactobacillus - drug effects | Obesity - etiology | Lactobacillus - enzymology | Taurocholic Acid - analogs & derivatives | Bacterial Proteins - antagonists & inhibitors | Microbiota - physiology | Signal Transduction | Amidohydrolases - genetics | Bacterial Proteins - genetics | Gene Expression Regulation | Amidohydrolases - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - genetics | Antioxidants - pharmacology | Mice, Knockout | Obesity - metabolism | Animals | Intestines - microbiology | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Lipid Metabolism - drug effects | Glucose - metabolism | Bacterial Proteins - biosynthesis | Mice | Anti-Obesity Agents - pharmacology | Index Medicus
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Loading RightsThe Journal of pharmacology and experimental therapeutics, 12/2017, Volume 363, Issue 3, p. 314
Endocannabinoids - pharmacology | Male | Cannabinol - pharmacology | Drug Agonism | Enzyme Inhibitors - administration & dosage | Monoacylglycerol Lipases - metabolism | Glycerides - agonists | Cannabinoid Receptor Antagonists - pharmacology | Behavior, Animal - drug effects | Adamantane - administration & dosage | Adamantane - analogs & derivatives | Enzyme Inhibitors - adverse effects | Cannabinol - adverse effects | Adamantane - pharmacology | Cannabinol - analogs & derivatives | Nerve Tissue Proteins - agonists | Enzyme Inhibitors - pharmacology | Saimiri | Cannabinoid Receptor Antagonists - adverse effects | Glycerides - administration & dosage | Glycerides - pharmacology | Arachidonic Acids - antagonists & inhibitors | Endocannabinoids - administration & dosage | Ligands | Cannabinoid Receptor Antagonists - administration & dosage | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Endocannabinoids - antagonists & inhibitors | Drugs, Investigational - adverse effects | Drugs, Investigational - pharmacology | Injections, Intravenous | Endocannabinoids - agonists | Monoacylglycerol Lipases - antagonists & inhibitors | Arachidonic Acids - agonists | Dose-Response Relationship, Drug | Discrimination Learning - drug effects | Receptor, Cannabinoid, CB1 - agonists | Arachidonic Acids - administration & dosage | Adamantane - adverse effects | Amidohydrolases - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Cannabinol - administration & dosage | Amidohydrolases - antagonists & inhibitors | Injections, Intramuscular | Arachidonic Acids - pharmacology | Nerve Tissue Proteins - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Drug Antagonism | Drugs, Investigational - administration & dosage | Glycerides - antagonists & inhibitors
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Loading RightsHypertension (Dallas, Tex. 1979), ISSN 0194-911X, 2014, Volume 64, Issue 3, pp. 619 - 625