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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 08/2007, Volume 293, Issue 2, pp. 909 - 918
Recent studies have uncovered important cross talk between inflammation, generation of reactive oxygen and nitrogen species, and lipid metabolism in the... 
Pressure-volume relationship | Cardiac function | Endocannabinoids | Anandamide | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ANANDAMIDE HYDROLYSIS | HEART-FAILURE | ENDOGENOUS CANNABINOID SYSTEM | ENDOCANNABINOID SYSTEM | RECEPTOR | KNOCKOUT MICE | CORONARY-ARTERIES | HEMODYNAMIC PROFILE | pressure-volume relationship | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | cardiac function | endocannabinoids | VASCULAR ENDOTHELIAL-CELLS | anandamide | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Humans | Monocytes - metabolism | NF-kappa B - metabolism | Coronary Vessels - metabolism | Receptors, Cannabinoid - metabolism | Arachidonic Acids - metabolism | Inflammation - metabolism | Aging - genetics | Ventricular Dysfunction, Left - genetics | Myocardium - metabolism | Ventricular Dysfunction, Left - pathology | Ventricular Dysfunction, Left - enzymology | Amidohydrolases - deficiency | Amidohydrolases - metabolism | Endothelial Cells - metabolism | Reactive Nitrogen Species - metabolism | Amidohydrolases - genetics | Cells, Cultured | Gene Expression Regulation | Polyunsaturated Alkamides - metabolism | Cell Adhesion | Aging - pathology | Mice, Knockout | Ventricular Dysfunction, Left - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Myocardium - enzymology | Animals | Coronary Vessels - cytology | Inflammation - genetics | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Inflammation - enzymology | Aging - metabolism | Apoptosis | Studies | Cardiovascular system | Rodents | Aging | Gene expression | Fatty acids | Index Medicus
Journal Article
Molecular Immunology, ISSN 0161-5890, 07/2013, Volume 54, Issue 3-4, pp. 482 - 492
► Oral treatment with α,β-amyrin ameliorate disease activity in DSS-induced colitis. ► α,β-Amyrin treatment decrease leukocyte influx to the colon. ► The... 
Inflammatory bowel disease | α,β-Amyrin | Dextran sodium sulfate | Inflammatory cytokines | Cannabinoid system | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | alpha,beta-amyrin | MECHANISMS | BETA-AMYRIN | ADHESION MOLECULES | IMMUNOLOGY | PROTIUM-HEPTAPHYLLUM | ALPHA-AMYRIN | INFLAMMATORY-BOWEL-DISEASE | MOUSE MODEL | RECEPTORS | EXPRESSION | P-Selectin - metabolism | Colitis - genetics | Tumor Necrosis Factor-alpha - genetics | Colon - drug effects | Body Weight - drug effects | Ki-67 Antigen - metabolism | Male | Interleukin-1beta - genetics | Antigens, CD - genetics | Body Weight - genetics | Antigens, CD - metabolism | Lectins, C-Type - metabolism | Interleukin-1beta - metabolism | Cannabinoids - genetics | Colitis - drug therapy | Cannabinoids - metabolism | Administration, Oral | CD18 Antigens - genetics | Membrane Proteins - genetics | Asialoglycoproteins - metabolism | P-Selectin - genetics | Cell Adhesion Molecules - metabolism | Chemokines - genetics | Colon - metabolism | CD18 Antigens - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Receptor, Cannabinoid, CB1 - genetics | Ki-67 Antigen - genetics | Intercellular Adhesion Molecule-1 - genetics | Colitis - metabolism | Chemokines - metabolism | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dextran Sulfate | Cell Adhesion Molecules - genetics | Oleanolic Acid - analogs & derivatives | Oleanolic Acid - pharmacology | Lectins, C-Type - genetics | Receptor, Cannabinoid, CB2 - genetics | Asialoglycoproteins - genetics | Colitis - chemically induced | Vascular Cell Adhesion Molecule-1 - genetics | Membrane Proteins - metabolism | Interleukin-4 - genetics | Amidohydrolases - metabolism | Amidohydrolases - genetics | Interleukin-4 - metabolism | RNA, Messenger - genetics | Up-Regulation - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Up-Regulation - drug effects | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Peroxidase - genetics | Peroxidase - metabolism | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7654, pp. 311 - 316
Nutrient signalling integrates and coordinates gene expression, metabolism and growth. However, its primary molecular mechanisms remain incompletely understood... 
TRANSCRIPTION FACTORS | ARABIDOPSIS ROOTS | METABOLISM | GLUCOSE | MULTIDISCIPLINARY SCIENCES | TRANSIENT GENE-EXPRESSION | CALCIUM | PROTOPLASTS | STRESS | TRANSLATION | PROTEIN-KINASES | Protein Kinases - metabolism | Plant Shoots - growth & development | Phosphorylation | Protein Kinases - genetics | Arabidopsis - growth & development | Calcium - metabolism | Transcriptome | Protein Kinases - chemistry | Biomass | Cellular Reprogramming | Arabidopsis Proteins - metabolism | Plants, Genetically Modified | Gene Expression Regulation, Plant | Transcription, Genetic | Plant Roots - growth & development | Calcium Signaling | Food | Amidohydrolases - metabolism | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Amino Acid Sequence | Carbon - metabolism | Arabidopsis Proteins - genetics | Nitrogen - metabolism | Plant Roots - metabolism | Calcium-Calmodulin-Dependent Protein Kinases - genetics | Oxidation-Reduction | Signal Transduction | Amidohydrolases - genetics | Arabidopsis - metabolism | Arabidopsis - genetics | Calcium-Calmodulin-Dependent Protein Kinases - chemistry | Nitrates - metabolism | Arabidopsis Proteins - chemistry | Plant Shoots - metabolism | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Calcium-Binding Proteins - genetics | Transcription factors | Calcium | Architecture | Nitrates | Lethality | Hormones | Plants | Gene expression | Metabolism | Calcium nitrate | Mutants | Calcium signalling | Leaves | Signal transduction | Molecular modelling | Nitrate | Redox reactions | Nutrients | Plasticity (developmental) | Flowers & plants | Index Medicus | Life Sciences
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7391, pp. 623 - 626
Many bacterial pathogens can enter various host cells and then survive intracellularly, transiently evade humoral immunity, and further disseminate to other... 
PASTEURELLA-MULTOCIDA TOXIN | PROTEIN-KINASE-C | ACTIVATION | CATALYTIC TRIAD | MOLECULAR-GRAPHICS | TRAF6 | MULTIDISCIPLINARY SCIENCES | CRYSTAL-STRUCTURES | HOST | NF-KAPPA-B | PATHOGENS | Shigella flexneri - genetics | Humans | Shigella flexneri - pathogenicity | Glutamine - metabolism | Molecular Sequence Data | Crystallography, X-Ray | NF-kappa B - metabolism | Histidine - metabolism | Neoplasm Proteins - metabolism | Ubiquitin-Conjugating Enzymes - chemistry | Inflammation - metabolism | Caspases - metabolism | Shigella flexneri - immunology | Diglycerides - metabolism | DNA Mutational Analysis | HEK293 Cells | Cysteine - metabolism | Shigella flexneri - enzymology | TNF Receptor-Associated Factor 6 - genetics | Dysentery, Bacillary - microbiology | Amidohydrolases - metabolism | Amino Acid Sequence | Biocatalysis | Amidohydrolases - genetics | Catalytic Domain - genetics | Models, Molecular | Ubiquitin-Conjugating Enzymes - genetics | Inflammation - immunology | Amidohydrolases - chemistry | Immunity, Innate | TNF Receptor-Associated Factor 6 - deficiency | Animals | Diglycerides - antagonists & inhibitors | Ubiquitin-Conjugating Enzymes - metabolism | B-Cell CLL-Lymphoma 10 Protein | TNF Receptor-Associated Factor 6 - metabolism | Aspartic Acid - metabolism | Virulence Factors - metabolism | Glutamic Acid - metabolism | Mice | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Inflammation - enzymology | Physiological aspects | Development and progression | Shigella flexneri | Cellular signal transduction | Genetic aspects | Inflammation | Risk factors | Proteins | Enzymes | Phosphorylation | Bacterial infections | Plasmids | Bacteria | Ligands | Infections | Kinases | Chemokines | Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2011, Volume 333, Issue 6049, pp. 1630 - 1632
Pyrazinamide (PZA) is a first-line tuberculosis drug that plays a unique role in shortening the duration of tuberculosis chemotherapy. PZA is hydrolyzed... 
Proteins | Tuberculosis | Mycobacterium tuberculosis | REPORTS | Ribosomes | Power of attorney | Amino acids | Bacteria | Geometric lines | Codons | Genetic mutation | PYRAZINOIC ACID | SYNTHASE | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | SUSCEPTIBILITY | RESISTANCE | PNCA MUTATIONS | BINDING | RIBOSOMAL-PROTEIN S1 | TMRNA | Ribosomal Proteins - chemistry | Bacterial Proteins - chemistry | Drug Resistance, Bacterial | Molecular Sequence Data | Ribosomes - metabolism | RNA, Messenger - metabolism | Mycobacterium tuberculosis - drug effects | Prodrugs - metabolism | Ribosomal Proteins - metabolism | Pyrazinamide - pharmacology | Mycobacterium tuberculosis - metabolism | RNA, Bacterial - metabolism | Pyrazinamide - metabolism | Amidohydrolases - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Pyrazinamide - analogs & derivatives | RNA, Transfer - metabolism | Ribosomal Proteins - genetics | Amidohydrolases - genetics | Antitubercular Agents - pharmacology | Bacterial Proteins - genetics | Mutant Proteins - metabolism | Protein Binding | Bacterial Proteins - metabolism | Protein Biosynthesis - drug effects | Mutation | Antitubercular Agents - metabolism | Prodrugs - pharmacology | Mycobacterium tuberculosis - genetics | Physiological aspects | Development and progression | Genetic aspects | Research | Pyrazinamide | Health aspects | Genetic translation | Enzymes | Chemotherapy | Inhibitor drugs | Index Medicus
Journal Article
Obesity, ISSN 1930-7381, 03/2008, Volume 16, Issue 3, pp. 553 - 565
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 04/2008, Volume 10, Issue 2, pp. R43 - R43
Introduction Cannabis-based medicines have a number of therapeutic indications, including anti- inflammatory and analgesic effects. The endocannabinoid... 
C-REACTIVE PROTEIN | CB2 RECEPTORS | NEUROPATHIC PAIN | ACTIVATION | RAT | ACID AMIDE HYDROLASE | INFLAMMATORY PAIN | RHEUMATOLOGY | MECHANICALLY EVOKED-RESPONSES | BONE MASS | DORSAL-HORN | Mitogen-Activated Protein Kinase 3 - analysis | Cytokines - analysis | Humans | Middle Aged | Synovial Fluid - metabolism | RNA, Messenger - analysis | Male | Synovial Fluid - chemistry | Arthritis, Rheumatoid - metabolism | Arachidonic Acids - analysis | Arachidonic Acids - metabolism | Piperidines - pharmacology | Glycerides - analysis | Mass Spectrometry | Chromatography, Liquid | Female | Phosphorylation - drug effects | Amidohydrolases - analysis | Endocannabinoids | Fibroblasts - metabolism | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Knee Joint - metabolism | Cytokines - metabolism | Cells, Cultured | Osteoarthritis - metabolism | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Mitogen-Activated Protein Kinase 1 - analysis | Polyunsaturated Alkamides - analysis | Synovial Membrane - metabolism | Blotting, Western | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Aged | Mitogen-Activated Protein Kinase 1 - metabolism | Synovial fluid | Cannabinoids | Dosage and administration | Research | Drug therapy | Osteoarthritis | Health aspects | Index Medicus
Journal Article
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2015, Volume 79, pp. 41 - 50
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2008, Volume 33, Issue 1, pp. 57 - 71
Journal Article