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Pharmacological Research, ISSN 1043-6618, 09/2012, Volume 66, Issue 3, pp. 251 - 259
Endocannabinoids exhibit vasodilatory properties and reduce blood pressure . However, the influence and mechanism of action of the prominent endocannabinoid,... 
Endocannabinoid | Abnormal cannabidiol | Pulmonary artery | Anandamide | Endothelium | VIRODHAMINE | VASORELAXATION | SMALL MESENTERIC-ARTERY | CANNABINOID RECEPTOR | VESSELS | VASCULATURE | RESISTANCE | PHARMACOLOGY & PHARMACY | CHANNELS | HYPERTENSION | ABNORMAL-CANNABIDIOL | Tetraethylammonium - pharmacology | Endocannabinoids - pharmacology | Rats, Wistar | Capsaicin - pharmacology | Anisoles - pharmacology | Cyclohexanes - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Apamin - pharmacology | Receptors, Cannabinoid - metabolism | TRPV Cation Channels - metabolism | Piperidines - pharmacology | Charybdotoxin - pharmacology | TRPV Cation Channels - antagonists & inhibitors | Potassium Chloride - metabolism | Cannabinoid Receptor Antagonists - pharmacology | Indoles - pharmacology | Benzamides - pharmacology | Potassium Channel Blockers - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Amidohydrolases - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Receptors, Epoprostenol - metabolism | Rats | Amidohydrolases - antagonists & inhibitors | Capsaicin - analogs & derivatives | Imidazoles - pharmacology | Pulmonary Artery - drug effects | Arachidonic Acids - pharmacology | Indomethacin - pharmacology | Receptors, Epoprostenol - antagonists & inhibitors | Animals | Benzyl Compounds - pharmacology | Endothelium, Vascular - metabolism | Prostaglandin-Endoperoxide Synthases - metabolism | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Polyunsaturated Alkamides - pharmacology | Nitric Oxide Synthase - metabolism | Vasodilation - drug effects | Hypertension | Enzymes | Vasodilators | Blood vessels | Glycerol | Fatty acids | Pulmonary hypertension | Glycerin | Cannabinoids | Dilatation | Dimethyl sulfoxide | Hydrolases | Indomethacin
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 02/2009, Volume 34, Issue 3, pp. 593 - 606
Journal Article
Hippocampus, ISSN 1050-9631, 10/2017, Volume 27, Issue 10, pp. 1093 - 1109
Exposure to excessive or uncontrolled stress is a major factor associated with various diseases including posttraumatic stress disorder (PTSD). The... 
URB597 | LTP | CB1 | extinction | posttraumatic stress disorder (PTSD) | receptors | CONDITIONED TASTE-AVERSION | BASOLATERAL AMYGDALA | CONTEXTUAL FEAR | ENDOCANNABINOID SYSTEM | EMOTIONAL MEMORY | SYNAPTIC PLASTICITY | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | GLUCOCORTICOID-RECEPTOR ACTIVATION | CB1 RECEPTOR | PITUITARY-ADRENAL AXIS | Cannabinoid Receptor Modulators - pharmacology | Memory - drug effects | Amygdala - physiopathology | Amygdala - drug effects | Stress Disorders, Post-Traumatic - pathology | Fear - drug effects | Neuronal Plasticity - drug effects | Male | Hippocampus - drug effects | Stress Disorders, Post-Traumatic - physiopathology | Fear - physiology | Receptors, Cannabinoid - metabolism | Neuronal Plasticity - physiology | Piperidines - pharmacology | Stress Disorders, Post-Traumatic - drug therapy | Benzamides - pharmacology | Carbamates - pharmacology | Disease Models, Animal | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Amidohydrolases - antagonists & inhibitors | Hippocampus - pathology | Stress Disorders, Post-Traumatic - psychology | Avoidance Learning - physiology | Magnesium - pharmacology | Rats, Sprague-Dawley | Amygdala - pathology | Cannabinoids - pharmacology | Naphthalenes - pharmacology | Animals | Benzoxazines - pharmacology | Glutamates - pharmacology | Avoidance Learning - drug effects | Bromine - pharmacology | Electroshock | Hippocampus - physiopathology | Drug Combinations | Memory - physiology | Prevention | Phenols | Cannabinoids | Fatty acids | Analysis | Post-traumatic stress disorder | Potentiation | Fatty-acid amide hydrolase | Shock | Amygdala | Hydrolase | Extinction | Long-term potentiation | Taste aversion | Cannabinoid CB1 receptors | Plasticity (hippocampal) | Trauma | Animal behavior | Rodents | Short term memory | Hippocampus | Long-term effects
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 05/2018, Volume 43, Issue 6, pp. 1284 - 1296
Exposure to a traumatic event may result in the development of post-traumatic stress disorder (PTSD). Endocannabinoids are crucial modulators of the stress... 
SYSTEM | 2-ARACHIDONOYLGLYCEROL | ANXIETY | PSYCHIATRY | ANANDAMIDE | POSTTRAUMATIC-STRESS | EXPOSURE THERAPY | NEUROSCIENCES | INACTIVATION | CONTEXTUAL FEAR MEMORY | DISORDER | PHARMACOLOGY & PHARMACY | MODULATION | Cannabinoid Receptor Modulators - pharmacology | Endocannabinoids - metabolism | Synaptic Transmission - physiology | Stress Disorders, Post-Traumatic - metabolism | Extinction, Psychological - drug effects | Male | Arachidonic Acids - metabolism | Piperidines - pharmacology | Stress Disorders, Post-Traumatic - drug therapy | Psychotropic Drugs - pharmacology | Synaptic Transmission - drug effects | Benzamides - pharmacology | Social Isolation | Extinction, Psychological - physiology | Carbamates - pharmacology | Disease Models, Animal | Amidohydrolases - metabolism | Morpholines - pharmacology | Amidohydrolases - antagonists & inhibitors | Glycerides - metabolism | Rats, Sprague-Dawley | Naphthalenes - pharmacology | Animals | Benzoxazines - pharmacology | Electroshock | Benzodioxoles - pharmacology | Drugs | Therapy | Mental disorders | Memory | Posttraumatic stress disorder | Neuromodulation | Modulators | Risk factors | Mimicry | Training | Learning | Receptors | Social behavior | 2-Arachidonylglycerol | Social interactions | Post-traumatic stress disorder | Rats | Pharmacology | Exposure | Cannabinoid CB1 receptors | Trauma | Anandamide | Hydrolysis | Post traumatic stress disorder | Inhibitors | Social interaction | Social isolation | Neurotransmission | Hippocampus | Original
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2008, Volume 28, Issue 51, pp. 13985 - 13994
Nicotine stimulates the activity of mesolimbic dopamine neurons, which is believed to mediate the rewarding and addictive properties of tobacco use.... 
Peroxisome proliferator-activated receptor | Electrophysiology | Fatty acid amide hydrolase | Patch clamp | Dopamine neurons | Endocannabinoids | Nicotine | PPAR-ALPHA | nicotine | patch clamp | ANANDAMIDE HYDROLYSIS | NEUROSCIENCES | MOUSE THALAMIC SYNAPTOSOMES | VENTRAL TEGMENTAL AREA | AMIDE HYDROLASE | dopamine neurons | ACETYLCHOLINE-RECEPTORS | fatty acid amide hydrolase | ESTER URB597 | electrophysiology | CORTICAL-NEURONS | endocannabinoids | INFLAMMATORY PAIN | peroxisome proliferator-activated receptor | CB1 RECEPTORS | PPAR alpha - drug effects | Cannabinoid Receptor Antagonists | Protein-Tyrosine Kinases - metabolism | Injections, Intraventricular | Male | Ventral Tegmental Area - cytology | Nicotine - pharmacology | Receptors, Cannabinoid - metabolism | Piperidines - pharmacology | Benzamides - pharmacology | Neurons - metabolism | Oleic Acids - pharmacology | Palmitic Acids - pharmacology | Neurons - drug effects | Dopamine - metabolism | Organ Culture Techniques | Carbamates - pharmacology | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Ventral Tegmental Area - drug effects | Appetite Depressants - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Amidohydrolases - antagonists & inhibitors | Enzyme Activation - drug effects | Ethanolamines | Nicotine - antagonists & inhibitors | Rats, Sprague-Dawley | Arachidonic Acids - pharmacology | Patch-Clamp Techniques | Animals | Rimonabant | Ventral Tegmental Area - metabolism | PPAR alpha - metabolism | Lipoxygenase Inhibitors - pharmacology
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2005, Volume 48, Issue 16, pp. 5059 - 5087
Journal Article
Behavioural Pharmacology, ISSN 0955-8810, 04/2014, Volume 25, Issue 2, pp. 182 - 185
Several allosteric modulators (AMs) of the CB1 receptor have been characterized in vitro, including Org27569, which enhances CB1-specific binding of... 
mouse | CP55 | rimonabant | cannabinoid | a940 | anandamide | allosteric modulator | CP55,940 | NEUROSCIENCES | INTERNALIZATION | DISPLAY | CB1 | CANNABINOID CB1 RECEPTORS | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | Delta 9-tetrahydrocannabinol | AGONIST | Cannabinoid Receptor Modulators - pharmacology | Cannabinoid Receptor Modulators - pharmacokinetics | Catalepsy - drug therapy | Endocannabinoids - pharmacology | Allosteric Regulation | Drug Evaluation | Nociception - physiology | Catalepsy - metabolism | Male | Hypothermia - chemically induced | Cannabinoid Receptor Agonists - pharmacology | Eating - physiology | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Hypothermia - metabolism | Nociception - drug effects | Cannabinoid Receptor Antagonists - pharmacology | Catalepsy - chemically induced | Female | Indoles - pharmacology | Piperidines - pharmacokinetics | Cyclohexanols - pharmacology | Dronabinol - pharmacology | Pyrazoles - pharmacology | Amidohydrolases - metabolism | Amidohydrolases - genetics | Mice, Inbred C57BL | Arachidonic Acids - pharmacology | Mice, Inbred ICR | Mice, Knockout | Eating - drug effects | Receptor, Cannabinoid, CB1 - metabolism | Animals | Receptor, Cannabinoid, CB1 - genetics | Hypothermia - drug therapy | Polyunsaturated Alkamides - pharmacology | Indoles - pharmacokinetics | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Index Medicus | 940 | Δ9-tetrahydrocannabinol
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1232 - 1238
Primary astrocytomas of grade 3 or 4 according to the classification system of the World Health Organization (high-grade astrocytomas or HGAs) are preponderant... 
MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | ADULT NEUROGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | MICE LACKING | CELL BIOLOGY | CANNABINOID RECEPTORS | GLIOBLASTOMA | ACID AMIDE HYDROLASE | IN-VIVO | VANILLOID RECEPTOR TRPV1 | GLIAL PROGENITORS | Endocannabinoids - pharmacology | Capsaicin - pharmacology | Capsaicin - therapeutic use | Humans | Male | Antineoplastic Agents - therapeutic use | Brain - metabolism | Oleic Acids - metabolism | Arachidonic Acids - metabolism | TRPV Cation Channels - biosynthesis | Glioblastoma - metabolism | Amidohydrolases - deficiency | Palmitic Acids - pharmacology | Neoplasm Proteins - genetics | Real-Time Polymerase Chain Reaction | Dopamine - metabolism | Tumor Cells, Cultured - drug effects | Capsaicin - analogs & derivatives | Brain Neoplasms - drug therapy | Mice, Knockout | Glioblastoma - pathology | Polyunsaturated Alkamides - pharmacology | Mice | Glioblastoma - drug therapy | Aging - metabolism | Cell Movement | Endocannabinoids - metabolism | Ethanolamines - pharmacology | TRPV Cation Channels - analysis | Neoplasm Proteins - physiology | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Culture Media, Conditioned - pharmacology | Brain - growth & development | Brain Neoplasms - metabolism | Tumor Cells, Cultured - pathology | Female | Oleic Acids - pharmacology | TRPV Cation Channels - physiology | Neoplasm Proteins - biosynthesis | Amidohydrolases - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | TRPV Cation Channels - agonists | Dopamine - pharmacology | Neural Stem Cells - physiology | Mice, SCID | Arachidonic Acids - pharmacology | TRPV Cation Channels - genetics | Animals | Dopamine - analogs & derivatives | Neoplasm Proteins - agonists | Neural Stem Cells - metabolism | Apoptosis | Care and treatment | Cell death | Brain tumors | Genetic aspects | Diagnosis | Research | Gene expression | Astrocytoma | Pediatrics | Signal transduction | Brain cancer | Neurobiology | Cell and Molecular Biology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell- och molekylärbiologi | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 2008, Volume 89, Issue 1, pp. 64 - 75
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2009, Volume 330, Issue 3, pp. 902 - 910
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/2012, Volume 165, Issue 8, pp. 2598 - 2610
BACKGROUND AND PURPOSE Activation of cannabinoid receptors decreases emesis, inflammation, gastric acid secretion and intestinal motility. The ability to... 
Caco‐2 cells | endocannabinoid | cannabinoid CB1 receptor | intestinal permeability | inflammation | cytokines | Δ9‐tetrahydrocannabinol and cannabidiol | transepithelial electrical resistance (TEER) | Cannabinoid CB | tetrahydrocannabinol and cannabidiol | Caco-2 cells | receptor | Cytokines | Endocannabinoid | Intestinal permeability | Transepithelial electrical resistance (TEER) | Inflammation | SYSTEM | ACTIVATION | CANNABIDIOL | Delta-tetrahydrocannabinol and cannabidiol | GASTROINTESTINAL-TRACT | ANANDAMIDE | NECROSIS-FACTOR-ALPHA | CELL-DEATH | BOWEL-DISEASE | ENDOCANNABINOIDS | PHARMACOLOGY & PHARMACY | CB1 RECEPTORS | Caco-2 Cells | Cell Survival - drug effects | Permeability - drug effects | Monoacylglycerol Lipases - antagonists & inhibitors | Humans | Enzyme Inhibitors - pharmacology | Amidohydrolases - antagonists & inhibitors | Intestines - metabolism | Cannabinoids - pharmacology | Receptor, Cannabinoid, CB1 - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Inflammation - metabolism | Piperidines - pharmacology | Indoles - pharmacology | Benzamides - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Benzodioxoles - pharmacology | Interferon-gamma - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Δ9-tetrahydrocannabinol and cannabidiol | Research Papers | Themed Section
Journal Article