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Journal Article
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 01/2013, Volume 83, Issue 1, pp. 22 - 32
Journal Article
eLife, ISSN 2050-084X, 05/2014, Volume 3, Issue 3, pp. e02523 - e02523
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 450 - 463
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2011, Volume 31, Issue 6, pp. 2101 - 2112
Ischemic brain injury is a major problem associated with stroke. It has been increasingly recognized that acid-sensing ion channels (ASICs) contribute... 
CALCIUM | RECEPTOR | SENSING ION-CHANNEL | INDUCED NEUROTOXICITY | RAT-BRAIN | POLYAMINE TRANSPORT | CEREBRAL-ISCHEMIA | HIPPOCAMPAL-NEURONS | ACTIVATED CURRENTS | CONTRIBUTES | NEUROSCIENCES | Electric Stimulation | Calcium - metabolism | Embryo, Mammalian | Amino Acid Transport System y+ - metabolism | Drug Interactions | Oligonucleotides - pharmacology | Time Factors | Sodium Channels - metabolism | Amino Acid Transport System y+ - deficiency | Disease Models, Animal | Membrane Potentials - drug effects | Brain Injuries - chemically induced | Excitatory Amino Acid Antagonists - pharmacology | Mutation - genetics | Extracellular Fluid - drug effects | GABA Antagonists - adverse effects | Mice, Knockout | Picrotoxin - adverse effects | Spermine - pharmacology | Hypoxia | Mice | Sodium Channels - genetics | Hydrogen-Ion Concentration | L-Lactate Dehydrogenase - metabolism | Neurons - pathology | Membrane Potentials - genetics | Cricetulus | Spermine - adverse effects | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Tetrazolium Salts | Transfection | Amino Acid Transport System y+ - antagonists & inhibitors | Neurons - physiology | Acidosis - physiopathology | Putrescine - pharmacology | Neurons - drug effects | CHO Cells | Cricetinae | Acid Sensing Ion Channels | Valine - analogs & derivatives | Cells, Cultured | Biophysics | Infarction, Middle Cerebral Artery - pathology | Hippocampus - cytology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Glucose - deficiency | Animals | Valine - pharmacology | Drug Combinations | Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 10/2013, Volume 104, Issue 10, pp. 1323 - 1329
Cancer development is often preceded by the appearance of preneoplastic lesions. In gastric carcinogenesis, chronic inflammation and histopathologic... 
OXYNTIC ATROPHY | WILD-TYPE | ONCOLOGY | GASTRIC-CANCER | ACTIVATED MACROPHAGES | TUMOR-CELLS | PROSTAGLANDIN E-2 PATHWAY | HELICOBACTER-PYLORI | CARCINOMA | CD44 | TRANSGENIC MICE | Adenocarcinoma - pathology | Adenocarcinoma - etiology | Humans | Neoplasm Proteins - physiology | Stomach Neoplasms - metabolism | Amino Acid Transport System y+ - genetics | Gastric Mucosa - pathology | Helicobacter Infections - complications | Precancerous Conditions - metabolism | Stomach Neoplasms - pathology | Sulfasalazine - pharmacology | Gastric Mucosa - metabolism | Hyaluronan Receptors - physiology | Adenocarcinoma - metabolism | Amino Acid Transport System y+ - antagonists & inhibitors | Precancerous Conditions - pathology | Neoplasm Proteins - genetics | Stomach Neoplasms - etiology | Amino Acid Transport System y+ - physiology | Biomarkers, Tumor - analysis | Neoplasm Proteins - biosynthesis | Mice, Inbred C57BL | Mice, Transgenic | Disease Progression | Protein Isoforms - physiology | Cocarcinogenesis | Metaplasia | Amino Acid Transport System y+ - biosynthesis | Adenocarcinoma - prevention & control | Animals | Cell Transformation, Neoplastic | Cystine - metabolism | Stomach Neoplasms - prevention & control | Mice | Peptides - analysis | Development and progression | Cysteine | Ablation (Surgery) | Analysis | Gastrointestinal diseases | Cystine | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 381, Issue 1, pp. 96 - 103
Highlights • Cystine starvation or glutamine excess leads to ferroptosis in head and neck cancer (HNC) cells. • Inhibition of cystine/glutamate antiporter... 
Hematology, Oncology and Palliative Medicine | Head and neck cancer | Ferroptosis | Lipid reactive oxygen species | Cisplatin resistance | Cystine/glutamate antiporter | TUMOR-REGRESSION | XCT | SENSITIVITY | SYSTEM XC(-) | ESTABLISHMENT | CYSTINE TRANSPORT | INHIBITION | ONCOLOGY | GLUTATHIONE | RADIOTHERAPY | ANTIPORTER | Reactive Oxygen Species - metabolism | Glutathione - metabolism | Humans | Glutamine - metabolism | Amino Acid Transport System y+ - genetics | Male | Sulfasalazine - pharmacology | Head and Neck Neoplasms - metabolism | Dose-Response Relationship, Drug | Amino Acid Transport System y+ - metabolism | Transfection | RNA Interference | Amino Acid Transport System y+ - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Head and Neck Neoplasms - drug therapy | Cisplatin - pharmacology | Piperazines - pharmacology | Head and Neck Neoplasms - pathology | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cystine - metabolism | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Mice, Inbred BALB C | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Biochemistry | Antineoplastic agents | Cell death | Glutamine | Chemotherapy | DNA damage | Conflicts of interest | Life sciences | Radiation therapy | Head & neck cancer | Cancer therapies | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus
Journal Article
Glia, ISSN 0894-1491, 08/2016, Volume 64, Issue 8, pp. 1381 - 1395
Journal Article