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Journal Article
Cancer Research, ISSN 0008-5472, 05/2016, Volume 76, Issue 10, pp. 2954 - 2963
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 3, pp. 387 - 400
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 2008, Volume 35, Issue 3, pp. 161 - 174
Journal Article
Science Translational Medicine, ISSN 1946-6234, 07/2014, Volume 6, Issue 247, pp. 247ra103 - 247ra103
Journal Article
Journal Article
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 12/2018, Volume 35, Issue 12, pp. 1 - 9
The anti-epileptic drug pregabalin crosses the blood-brain barrier (BBB) in spite of its low lipophilicity. This study was performed to determine whether... 
Biochemistry, general | blood-brain barrier | L-type amino acid transporter | Biomedicine | Pharmacy | Medical Law | pregabalin | Pharmacology/Toxicology | Biomedical Engineering and Bioengineering | anti-epileptic drug | SYSTEM-L | ACTIVATION | INVOLVEMENT | IDENTIFICATION | GABAPENTIN | CHEMISTRY, MULTIDISCIPLINARY | LAT1 | INHIBITION | FUNCTIONAL EXPRESSION | PHARMACOLOGY & PHARMACY | BARRIER MODEL | OCTN1 | Endothelium, Vascular - cytology | Cell Line | Leucine - metabolism | RNA, Small Interfering - genetics | Anticonvulsants - pharmacokinetics | Pregabalin - pharmacokinetics | Endothelial Cells - metabolism | Large Neutral Amino Acid-Transporter 1 - metabolism | Humans | Pregabalin - metabolism | Anticonvulsants - metabolism | Rats | Amino Acid Transport System y+ - genetics | Large Neutral Amino Acid-Transporter 1 - genetics | Fusion Regulatory Protein 1, Light Chains - genetics | Permeability | Blood-Brain Barrier - metabolism | Brain - blood supply | Amino Acid Transport System y+ - metabolism | Animals | Fusion Regulatory Protein 1, Light Chains - metabolism | Biological Transport | Endothelial Cells - drug effects | Brain | Amino acids | Pregabalin | RNA | Analysis | Endothelium | Heptanes | Epilepsy | mRNA | siRNA | Carboxylic acids | Gene expression | Substrates | Endothelial cells | Polymerase chain reaction | Inhibitors | Sodium | Blood-brain barrier | Inhibition | Transport | Transporter | Lipophilicity | Research Paper
Journal Article
Journal Article