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1. Full Text Renal amino acid transport systems and essential hypertension
by Pinto, Vanda and Pinho, Maria João and Soares-Da-Silva, Patrício
FASEB Journal, ISSN 0892-6638, 08/2013, Volume 27, Issue 8, pp. 2927 - 2938
Several clinical and animal studies suggest that "blood pressure goes with the kidney," that is, a normotensive recipient of a kidney genetically programmed... 
Blood pressure | Dopamine | Nitric oxide | Kidney | blood pressure | nitric oxide | LYSINURIC PROTEIN INTOLERANCE | OXIDATIVE STRESS | CL-/HCO3-EXCHANGER | MEDULLARY BLOOD-FLOW | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOPAMINERGIC SYSTEM | FUNCTIONAL-CHARACTERIZATION | CELL BIOLOGY | kidney | L-ARGININE | BIOLOGY | NITRIC-OXIDE | MOLECULAR-CLONING | dopamine | L-DOPA UPTAKE | Rats, Inbred SHR | Kidney - metabolism | Animals | Models, Biological | Humans | Rats | Amino Acid Transport Systems - metabolism | Levodopa - metabolism | Dopamine - metabolism | Hypertension - metabolism
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2. Full Text The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)
by Tsuchihashi, Kenji and Okazaki, Shogo and Ohmura, Mitsuyo and Ishikawa, Miyuki and Sampetrean, Oltea and Onishi, Nobuyuki and Wakimoto, Hiroaki and Yoshikawa, Momoko and Seishima, Ryo and Iwasaki, Yoshimi and Morikawa, Takayuki and Abe, Shinya and Takao, Ayumi and Shimizu, Misato and Masuko, Takashi and Nagane, Motoo and Furnari, Frank B and Akiyama, Tetsu and Suematsu, Makoto and Baba, Eishi and Akashi, Koichi and Saya, Hideyuki and Nagano, Osamu
Cancer Research, ISSN 0008-5472, 05/2016, Volume 76, Issue 10, pp. 2954 - 2963
Extracellular free amino acids contribute to the interaction between a tumor and its microenvironment through effects on cellular metabolism and malignant... 
CANCER-CELLS | SURVIVAL | GROWTH-FACTOR RECEPTOR | METABOLISM | ONCOLOGY | REDOX REGULATION | GLUTAMATE | ANTIPORTER | EXPRESSION | CD44 | MODULATION | Cell Proliferation | Reactive Oxygen Species - metabolism | Antioxidants - metabolism | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Sulfasalazine - pharmacology | Brain Neoplasms - metabolism | Glioma - metabolism | Receptor, Epidermal Growth Factor - metabolism | Amino Acid Transport System y+ - metabolism | Glioma - pathology | Cell Membrane - metabolism | Tumor Cells, Cultured | Brain Neoplasms - drug therapy | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cystine - metabolism | Mice, Inbred NOD | Glutamic Acid - metabolism | Mice | Glioma - drug therapy | Apoptosis | Cell Movement | xCT | glioma | epidermal growth factor receptor (EGFR) | matrix invasion | glutamate
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3. Full Text A systems perspective on placental amino acid transport
by Cleal, Jane K and Lofthouse, Emma M and Sengers, Bram G and Lewis, Rohan M
The Journal of Physiology, ISSN 0022-3751, 12/2018, Volume 596, Issue 23, pp. 5511 - 5522
 Transepithelial amino acid transfer across the placenta requires interaction between different classes of amino acid transporters. Net uptake of maternal... 
trans-epithelial transport | fetal growth restriction | computational modelling | PERFUSED HUMAN PLACENTA | MAMMALIAN TARGET | PHYSIOLOGY | NEUROSCIENCES | PREGNANCIES | METABOLISM | BASAL PLASMA-MEMBRANE | GLUTAMATE | GROWTH | SNAT4 ISOFORM | FETAL | TAURINE TRANSPORTER | Fetus | Calcifediol | Alfacalcidol | Phenylalanine | Vitamin D | Growth | Placenta | Limiting factors | Fetuses | Computer applications | Amino acids | Health risk assessment | Blood flow | Topical Review | Special Section Reviews
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4. QUANTITATIVE PROTEOMICS REVEAL OVERALL AMINO ACID TRANSPORT SYSTEMS AND THE RELATED SIGNALING
by Shushi Nagamori
Annals of Nutrition & Metabolism, ISSN 0250-6807, 10/2017, Volume 71, p. 140
Amino acids are known as building blocks of proteins and substrates of metabolic and biosynthetic reactions. However amino acids are also recognized as the... 
TOR protein | Cell proliferation | Biotechnology | Phosphorylation | Nutrient transport | Amino acids | Rapamycin | Leucine | Tumor cell lines | Metabolism | Nutrient uptake | Molecular chains | Substrates | Proteins | Signal transduction | Signaling | Pathways | Phosphoproteins | Proteomics | Cell lines | Nutrients | Transport | Transporter | Cancer
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5. F-18-fluorodihydroxyphenylalanine PET/CT in pheochromocytoma and paraganglioma: relation to genotype and amino acid transport system L
by Feral, CC and Tissot, FS and Tosello, L and Fakhry, N and Sebag, F and Pacak, K and Taieb, D
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, ISSN 1619-7070, 05/2017, Volume 44, Issue 5, pp. 812 - 821
F-FDOPA is a highly sensitive and specific radiopharmaceutical for pheochromocytoma and paraganglioma (PPGL) imaging. However, F-18-FDOPA might be falsely... 
CELLS | LAT1 | F-18-FDOPA | VIVO | CD98HC | FUNCTIONAL-CHARACTERIZATION | Paragangliomas | IDENTIFICATION | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Amino acid transport system L | DEFICIENCY
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6. Full Text Amino acid transport system - A substrate predicts the therapeutic effects of particle radiotherapy
by Uehara, Tomoya and Watanabe, Mariko and Suzuki, Hiroyuki and Furusawa, Yoshiya and Arano, Yasushi
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0173096
L-[methyl-C-11]Methionine (C-11-Met) is useful for estimating the therapeutic efficacy of particle radiotherapy at early stages of the treatment. Given the... 
POSITRON-EMISSION-TOMOGRAPHY | CLINICAL-APPLICATIONS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | METHIONINE-PET | TUMOR-TISSUE | CARBON ION RADIOTHERAPY | IMAGING AGENTS | CELL-LINES | PROTEIN-SYNTHESIS | C-11-METHIONINE PET | Amino Acids - metabolism | Animals | Heterografts | Methionine - metabolism | Humans | Radiotherapy - methods | Cell Line, Tumor | Carbon Radioisotopes - metabolism | Mice | Radiation Dosage | Salivary Glands - metabolism | Amino acids | Care and treatment | Usage | Radiotherapy | Analysis | Tumors | Nuclear magnetic resonance--NMR | Brain cancer | Radiation | Radioisotopes | Cancer therapies | Accumulation | Proteins | Energy | Xenografts | Half-life | Protein transport | Probes | Pharmaceutical sciences | Half life | Medical imaging | Tumor cells | Methionine | Salivary gland | Protein biosynthesis | Radioactive half-life | Radiation therapy | Metabolism | Carbon | Substrates | Radiation dosage | Ion beams | Studies | Acids | Protein synthesis | Irradiation | Diagnostic systems | Transport | Transporter | Nuclear magnetic resonance | NMR
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7. Full Text Molecular Cloning of Mouse Amino Acid Transport System B0, a Neutral Amino Acid Transporter Related to Hartnup Disorder
by Angelika Bröer and Karin Klingel and Sonja Kowalczuk and John E. J. Rasko and Juleen Cavanaugh and Stefan Bröer
Journal of Biological Chemistry, ISSN 0021-9258, 06/2004, Volume 279, Issue 23, pp. 24467 - 24476
Resorption of amino acids in kidney and intestine is mediated by transporters, which prefer groups of amino acids with similar physico-chemical properties. It... 
Skin - metabolism | Amino Acids - chemistry | Electrophysiology | Molecular Sequence Data | Substrate Specificity | Intestines - metabolism | Phylogeny | RNA, Messenger - metabolism | Anions | Kidney - metabolism | In Situ Hybridization | Biological Transport | Time Factors | Base Sequence | Cloning, Molecular | Mice, Inbred DBA | Protein Structure, Tertiary | RNA, Complementary - metabolism | Amino Acid Sequence | Peptides - chemistry | Oocytes - metabolism | Mice, Inbred C57BL | Ions | Reverse Transcriptase Polymerase Chain Reaction | Plasmids - metabolism | Amino Acid Transport Systems, Neutral - genetics | Leucine - chemistry | Animals | Models, Biological | Amino Acid Transport Systems - genetics | Cations | Mice | Models, Genetic | Hartnup Disease - metabolism | Mutation | DNA, Complementary - metabolism | Hydrogen-Ion Concentration
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8. 18F-fluorodihydroxyphenylalanine PET/CT in pheochromocytoma and paraganglioma: relation to genotype and amino acid transport system L
by Feral, Chloé C and Tissot, Floriane S and Tosello, Lionel and Fakhry, Nicolas and Sebag, Fréderic and Pacak, Karel and Taïeb, David
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 05/2017, Volume 44, Issue 5, pp. 812 - 821
Paragangliomas | Amino acid transport system L | F-FDOPA
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9. sup 18^F-fluorodihydroxyphenylalanine PET/CT in pheochromocytoma and paraganglioma: relation to genotype and amino acid transport system L
by Chloé C Feral and Floriane S Tissot and Lionel Tosello and Nicolas Fakhry and Fréderic Sebag and Karel Pacak and David Taïeb
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 05/2017, Volume 44, Issue 5, p. 812
  Purpose F-FDOPA is a highly sensitive and specific radiopharmaceutical for pheochromocytoma and paraganglioma (PPGL) imaging. However, 18F-FDOPA might be... 
Genotype & phenotype | Radioisotopes | Tomography | Amino acids | Tumors | Pharmaceuticals
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10. Full Text The SLC3 and SLC7 families of amino acid transporters
by Fotiadis, Dimitrios and Kanai, Yoshikatsu and Palacín, Manuel
Molecular Aspects of Medicine, ISSN 0098-2997, 04/2013, Volume 34, Issue 2-3, pp. 139 - 158
Amino acids are necessary for all living cells and organisms. Specialized transporters mediate the transfer of amino acids across plasma membranes. Malfunction... 
Cationic amino acid transporter | Heteromeric amino acid transporter | SLC7 | Aminoacidurias | L-Type amino acid transporter | Cancer | SLC3 | GENOTYPE-PHENOTYPE CORRELATION | MEDICINE, RESEARCH & EXPERIMENTAL | LYSINURIC PROTEIN INTOLERANCE | OXIDATIVE STRESS | ECOTROPIC RETROVIRUS RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | METABOTROPIC GLUTAMATE RECEPTORS | EXTRACELLULAR GLUTAMATE | CELL LUNG-CANCER | SYSTEM X(C)(-) | CYSTINE/GLUTAMATE EXCHANGE TRANSPORTER | 4F2 HEAVY-CHAIN | Multigene Family - genetics | Neoplasms - metabolism | Amino Acid Transport Systems, Basic - genetics | Humans | Models, Molecular | Amino Acid Transport Systems, Neutral - metabolism | Phylogeny | Amino Acid Transport Systems, Neutral - genetics | Amino Acid Transport Systems, Neutral - physiology | Models, Biological | Amino Acid Transport Systems, Basic - physiology | Protein Conformation | Biological Transport - physiology | Amino Acid Transport Systems, Basic - metabolism | Development and progression | Amino acids | Cats | Glycoproteins | Nitric oxide | Tumors
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11. Full Text Amino Acid Transport Across Mammalian Intestinal and Renal Epithelia
by Broer, Stefan
Physiological Reviews, ISSN 0031-9333, 01/2008, Volume 88, Issue 1, pp. 249 - 286
School of Biochemistry and Molecular Biology, Australian National University, Canberra, Australian Capital Territory, Australia The transport of amino acids in... 
BRUSH-BORDER-MEMBRANE | TISSUE EXPRESSION PATTERN | LYSINURIC PROTEIN INTOLERANCE | RAT-KIDNEY CORTEX | PHYSIOLOGY | BETA-ALANINE ABSORPTION | CHRONIC METABOLIC-ACIDOSIS | ELECTRO-PHYSIOLOGICAL ANALYSIS | BASOLATERAL PLASMA-MEMBRANE | AFFINITY GLUTAMATE TRANSPORTER | RABBIT PROXIMAL TUBULE | Amino Acids - metabolism | Kidney - metabolism | Animals | Epithelium - metabolism | Humans | Amino Acid Transport Systems - physiology | Biological Transport - physiology | Intestines - metabolism | Epithelial cells | Amino acid metabolism | Research
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12. Full Text A high-affinity, tryptophan-selective amino acid transport system in human macrophages
by Robert L. Seymour and Vadivel Ganapathy and Andrew L. Mellor and David H. Munn
Journal of Leukocyte Biology, ISSN 0741-5400, 12/2006, Volume 80, Issue 6, pp. 1320 - 1327
Tryptophan catabolism via the enzyme indoleamine 2,3‐dioxygenase (IDO) allows human monocyte‐derived macrophages (MDM) and other APC to suppress T cell... 
indoleamine 2,3‐dioxygenase | antigen‐presenting cells | tolerance | Tolerance | Antigen-presenting cells | Indoleamine 2,3-dioxygenase | HOST-CELLS | CATABOLISM | antigen-presenting cells | EXPRESSING INDOLEAMINE 2,3-DIOXYGENASE | DENDRITIC CELLS | IMMUNOLOGY | CELL BIOLOGY | T-CELL PROLIFERATION | INHIBITION | INTERFERON-GAMMA | HUMAN-FIBROBLASTS | DEGRADATION | MOLECULAR-CLONING | indoleamine 2,3-dioxygenase | HEMATOLOGY | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Cell Line | Cell Proliferation | T-Lymphocytes | Coculture Techniques | Humans | Immune Tolerance | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Tryptophan - metabolism | Macrophages - enzymology | Pregnancy - immunology | Cell Differentiation - immunology | Animals | Amino Acid Transport System L - immunology | Biological Transport, Active - immunology | Tryptophan - immunology | Female | Fetus - immunology | Mice | Macrophages - immunology
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13. Full Text Amino Acid Transport System A Resembles System N in Sequence but Differs in Mechanism
by Richard J. Reimer and Farrukh A. Chaudhry and Andrew T. Gray and Robert H. Edwards
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2000, Volume 97, Issue 14, pp. 7715 - 7720
Classical amino acid transport System A accounts for most of the Na -dependent neutral amino acid uptake by mammalian cells. System A has also provided a... 
Protons | Biological Sciences | Complementary DNA | Neurons | Neuroglia | HeLa cells | Amino acids | In situ hybridization | Electric current | Oocytes | VESICULAR GABA | NEUROTRANSMITTER TRANSPORTERS | HEAVY-CHAIN | RAT HEPATOCYTES | HAMSTER OVARY CELLS | GLUTAMATE | MULTIDISCIPLINARY SCIENCES | XENOPUS OOCYTES | DOPAMINE TRANSPORTER | CEREBRAL-CORTEX | A-SYSTEM | Recombinant Proteins - metabolism | Amino Acid Sequence | Amino Acid Transport Systems | Gene Library | Humans | Electrophysiology | Models, Molecular | Molecular Sequence Data | Rats | Sodium - metabolism | Sequence Analysis, DNA | Tissue Distribution | Amino Acids - metabolism | beta-Alanine - metabolism | Animals | Carrier Proteins - metabolism | In Situ Hybridization | Biological Transport | Membrane Potentials | Amino Acid Transport Systems, Neutral | Membrane Transport Proteins | Carrier Proteins - chemistry | beta-Alanine - analogs & derivatives | Physiological aspects | Biological transport
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