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Molecular Genetics and Metabolism, ISSN 1096-7192, 09/2018, Volume 125, Issue 1-2, pp. 118 - 126
Folate metabolism in the brain is critically important and serves a number of vital roles in nucleotide synthesis, single carbon metabolism/methylation, amino... 
Neurometabolism | Folinic acid | 5,10-methenyltetrahydrofolate synthetase | Neurodegeneration | Folate | MEDICINE, RESEARCH & EXPERIMENTAL | SERINE HYDROXYMETHYLTRANSFERASE | 5-FORMYLTETRAHYDROFOLATE | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | Metabolic Diseases - pathology | Microcephaly - genetics | Humans | Carbon-Nitrogen Ligases - cerebrospinal fluid | Tetrahydrofolates - cerebrospinal fluid | Male | Psychomotor Disorders - complications | Carbon-Nitrogen Ligases - genetics | Brain - metabolism | Nervous System Malformations - metabolism | Microcephaly - cerebrospinal fluid | Carbon-Nitrogen Ligases - deficiency | Antiporters - metabolism | Hereditary Central Nervous System Demyelinating Diseases - metabolism | Tetrahydrofolates - metabolism | Brain - pathology | Amino Acid Transport Systems, Acidic - cerebrospinal fluid | Neuroaxonal Dystrophies | Antiporters - cerebrospinal fluid | Metabolic Diseases - complications | Psychomotor Disorders - cerebrospinal fluid | Mitochondrial Diseases - cerebrospinal fluid | Amino Acid Transport Systems, Acidic - metabolism | Mitochondrial Diseases - metabolism | Amino Acid Transport Systems, Acidic - deficiency | Epilepsy - cerebrospinal fluid | Mitochondrial Diseases - complications | Psychomotor Disorders - metabolism | Psychomotor Disorders - genetics | Microcephaly - pathology | Antiporters - genetics | Epilepsy - genetics | Female | Nervous System Malformations - genetics | Hereditary Central Nervous System Demyelinating Diseases - genetics | Antiporters - deficiency | Mitochondrial Diseases - genetics | Microcephaly - complications | Carbon-Nitrogen Ligases - metabolism | Nervous System Malformations - cerebrospinal fluid | Folate Receptor 1 - deficiency | Metabolic Diseases - cerebrospinal fluid | Epilepsy - complications | Nervous System Malformations - complications | Amino Acid Transport Systems, Acidic - genetics | Metabolic Diseases - genetics | Hereditary Central Nervous System Demyelinating Diseases - cerebrospinal fluid | Hereditary Central Nervous System Demyelinating Diseases - complications | Epilepsy - pathology | Medical research | Metabolites | Ligases | Epilepsy | Physiological aspects | Medicine, Experimental | Amino acids | Leucovorin | Genetic translation | Folic acid
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 07/2017, Volume 142, Issue 1, pp. 132 - 139
ARALAR/AGC1 (aspartate‐glutamate mitochondrial carrier 1) is an important component of the NADH malate‐aspartate shuttle (MAS). AGC1‐deficiency is a rare... 
malate‐aspartate shuttle | ARALAR/AGC1 deficiency | magnetic resonance spectroscopy | mitochondrial aspartate‐glutamate carrier | lactate | mitochondrial disorders | malate-aspartate shuttle | mitochondrial aspartate-glutamate carrier | GLYCEROL-3-PHOSPHATE DEHYDROGENASE | TRANSCRIPTOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASTROCYTES | NEUROSCIENCES | SHUTTLE | REDUCED N-ACETYLASPARTATE | MOLECULAR WATER PUMP | MAGNETIC-RESONANCE | ENERGY-METABOLISM | EXPRESSION | ASPARTATE-GLUTAMATE CARRIER | Amino Acid Transport Systems, Acidic - deficiency | Nervous System Diseases - genetics | Psychomotor Disorders - genetics | Mitochondria - genetics | Antiporters - genetics | Nervous System Diseases - metabolism | Neurons - metabolism | Brain Chemistry - genetics | Hereditary Central Nervous System Demyelinating Diseases - genetics | Antiporters - deficiency | Mitochondrial Diseases - genetics | Lactic Acid - metabolism | Mice, Inbred C57BL | Mitochondria - metabolism | Aggrecans - metabolism | Aggrecans - genetics | Mice, Knockout | Animals | Oxygen Consumption - genetics | Amino Acid Transport Systems, Acidic - genetics | Glucose - metabolism | Glucosephosphate Dehydrogenase - metabolism | Mice | Glucosephosphate Dehydrogenase - genetics | Astrocytes - metabolism | Lactates | Aspartate | Nuclear magnetic resonance spectroscopy | Glutamate | Neurons | Phosphates | Brain | Glutamic acid | Epilepsy | Impairment | Neurodevelopmental disorders | Mitochondria | Hypotonia | NADH | Spacecraft components | Phosphate | Rodents | Bioindicators | Neurological disorders | Neurochemistry | Astrocytes | Glycerol | Carriers | Malate | Nicotinamide adenine dinucleotide | Lactic acid | Electron transport | Respiration
Journal Article
American Journal of Human Genetics, ISSN 0002-9297, 05/2015, Volume 96, Issue 5, pp. 709 - 719
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 06/2017, Volume 100, Issue 6, pp. 969 - 977
Journal Article
Neuron, ISSN 0896-6273, 2008, Volume 57, Issue 2, pp. 263 - 275
Journal Article
Neurology, ISSN 0028-3878, 10/2017, Volume 89, Issue 17, pp. 1821 - 1828
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 02/2013, Volume 124, Issue 3, pp. 347 - 362
The mitochondrial transporter of aspartate‐glutamate Aralar/AGC1 is a regulatory component of the malate‐aspartate shuttle. Aralar deficiency in mouse and... 
global cerebral hypomyelination | malate‐aspartate shuttle | OmniBank | dopamine | VMAT2 | AGC‐1 deficiency | malate-aspartate shuttle | AGC-1 deficiency | NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | NEUROSCIENCES | MICE LACKING | OmniBank (R) | METABOLISM | VESICULAR MONOAMINE TRANSPORTER-2 | MITOCHONDRIAL COMPLEX-I | MOUSE MODEL | NEURONS | RAT-BRAIN | EXPRESSION | Oxidative Stress - physiology | Amino Acid Transport Systems, Acidic - metabolism | Mitochondrial Diseases - metabolism | Dopamine - genetics | Amino Acid Transport Systems, Acidic - deficiency | Male | Hereditary Central Nervous System Demyelinating Diseases - physiopathology | Motor Skills Disorders - genetics | Mice, 129 Strain | Substantia Nigra - metabolism | Corpus Striatum - cytology | Corpus Striatum - metabolism | Substantia Nigra - cytology | Mitochondrial Membrane Transport Proteins - genetics | Dopamine - deficiency | Exploratory Behavior - physiology | Psychomotor Disorders - metabolism | Psychomotor Disorders - genetics | Mitochondrial Membrane Transport Proteins - deficiency | Antiporters - genetics | Malates - metabolism | Female | Neural Pathways - physiopathology | Psychomotor Disorders - physiopathology | Dopamine - metabolism | Hereditary Central Nervous System Demyelinating Diseases - genetics | Antiporters - deficiency | Emotions - physiology | Mitochondrial Diseases - genetics | Mitochondrial Membrane Transport Proteins - metabolism | Mice, Inbred C57BL | Antiporters - metabolism | Hereditary Central Nervous System Demyelinating Diseases - metabolism | Mice, Knockout | Pregnancy | Motor Skills Disorders - metabolism | Animals | Neural Pathways - cytology | Amino Acid Transport Systems, Acidic - genetics | Neural Pathways - metabolism | Aspartic Acid - metabolism | Mice | Aspartic Acid - physiology | Mitochondrial Diseases - physiopathology | Tyrosine | Phenols | Aspartate | Neurochemistry | Mitochondria | Dopamine | Brain | Reactive oxygen species | Hyperreactivity | Brain stem | Hyperactivity | Neurons | Substantia nigra | Cortex | Amino acids | Metabolism | Cytosol | Vesicular amine transporter | Amine oxidase (flavin-containing) | NADH | Neostriatum | Anxiety
Journal Article
Journal Article