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Science, ISSN 0036-8075, 2/2011, Volume 331, Issue 6020, pp. 1081 - 1084
Understanding the organization of a bacterial cell requires the elucidation of the mechanisms by which proteins localize to particular subcellular sites. Thus... 
Messenger RNA | Reverse transcriptase polymerase chain reaction | Microscopy | Antibiotics | B lymphocytes | Genes | REPORTS | Fluorescence | Cell membranes | Cytoplasm | P branes | CELLS | CHLORAMPHENICOL | INTRACELLULAR-LOCALIZATION | BACILLUS-SUBTILIS | MEMBRANE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | TRANSCRIPTION | GLOBAL ANALYSIS | PROTEINS | BINDING | Protein Kinases - metabolism | RNA-Binding Proteins - genetics | Transcription, Genetic - drug effects | Protein Kinases - genetics | Chloramphenicol O-Acetyltransferase - metabolism | Cytoplasm - metabolism | Chloramphenicol O-Acetyltransferase - genetics | RNA, Messenger - metabolism | Escherichia coli K12 - metabolism | beta-Glucosidase - genetics | Base Sequence | Chloramphenicol - pharmacology | RNA, Bacterial - genetics | beta-Glucosidase - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Nucleic Acid Conformation | Monosaccharide Transport Proteins - metabolism | RNA, Bacterial - metabolism | Monosaccharide Transport Proteins - genetics | Genes, Bacterial | Membrane Proteins - genetics | Operon | RNA, Messenger - genetics | Bacterial Proteins - genetics | Escherichia coli Proteins - metabolism | Symporters - metabolism | Protein Transport | RNA, Bacterial - chemistry | Symporters - genetics | Escherichia coli Proteins - genetics | Bacterial Proteins - metabolism | Protein Biosynthesis - drug effects | RNA, Messenger - chemistry | Aminoglycosides - pharmacology | Escherichia coli K12 - genetics | RNA-Binding Proteins - metabolism | Genetic aspects | Properties | Escherichia coli | Membrane proteins
Journal Article
Science, ISSN 0036-8075, 6/2013, Volume 340, Issue 6140, pp. 1583 - 1587
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2009, Volume 606, Issue 1, pp. 162 - 171
The protective role of diallyl sulfide (DAS) in attenuating gentamicin-induced nephrotoxicity has been reported earlier. However, the mechanism of induction of... 
Oxidative stress | Nephrotoxicity | Nuclear factor E2-related factor 2 (Nrf2) | Gentamicin | Reactive oxygen species (ROS) | Diallyl sulfide | NAD(P)H-QUINONE OXIDOREDUCTASE-1 | LIPID-PEROXIDATION | PROTECTION | CANCER | SUPEROXIDE ANION | GLUTATHIONE | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | MICE | NF-KAPPA-B | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Kidney - pathology | Rats, Wistar | Glutathione - metabolism | Male | NF-kappa B - metabolism | Gentamicins - toxicity | Ascorbic Acid - metabolism | Inflammation - metabolism | Kidney - metabolism | Inflammation - drug therapy | Lipid Peroxidation - drug effects | Anti-Inflammatory Agents - therapeutic use | Enzyme Induction - drug effects | Kidney Glomerulus - metabolism | Kidney Tubules - pathology | Kidney Tubules - metabolism | Sulfides - pharmacology | Biomarkers - metabolism | Kidney - drug effects | Kidney Tubules - drug effects | Anti-Inflammatory Agents - pharmacology | Kidney Glomerulus - drug effects | Rats | Sulfides - therapeutic use | Antioxidants - pharmacology | Kidney Glomerulus - pathology | Allyl Compounds - pharmacology | Allyl Compounds - therapeutic use | Animals | NF-E2-Related Factor 2 - metabolism | Vitamin E - metabolism | Oxidative Stress - drug effects | Nitric Oxide Synthase Type II - metabolism | Peroxidase - metabolism | Antioxidants | Sulfides | Glutathione transferase | Nitric oxide | Quinone | Superoxide dismutase | Aminoglycosides | Superoxide | Glutathione | Index Medicus
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 05/2007, Volume 34, Issue 5, pp. 399 - 405
SUMMARY • The present study investigated the possible protective effects of thymoquinone (TQ), a compound derived from Nigella sativa with strong anti-oxidant... 
thymoquinone | gentamicin | nephrotoxicity | ATP | oxidative stress | Oxidative stress | Nephrotoxicity | Gentamicin | Thymoquinone | NIGELLA-SATIVA OIL | ENCEPHALOMYELITIS | AMINOGLYCOSIDES | PHYSIOLOGY | MECHANISM | GLUTATHIONE-PEROXIDASE | ACID PHENETHYL ESTER | ANTITUMOR-ACTIVITY | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | INDUCED NEPHROTOXICITY | Benzoquinones - administration & dosage | Kidney - pathology | Rats, Wistar | Glutathione - metabolism | Blood Urea Nitrogen | Nitrites - metabolism | Male | Gentamicins - administration & dosage | Gentamicins - toxicity | Kidney - metabolism | Adenosine Triphosphate - metabolism | Nigella sativa - chemistry | Lipid Peroxidation - drug effects | Nitrites - blood | Acute Kidney Injury - chemically induced | Drug Therapy, Combination | Nitrates - blood | Glutathione Peroxidase - metabolism | Kidney - drug effects | Injections, Intraperitoneal | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Acute Kidney Injury - prevention & control | Benzoquinones - pharmacology | Catalase - metabolism | Nitrates - metabolism | Animals | Creatinine - blood | Dietary Supplements | Glutathione - blood | Kidney, drug effects | Benzoquinones, pharmacology | Gentamicins, toxicity | Glutathione, blood | Thiobarbituric Acid Reactive Substances, metabolism | Creatinine, blood | Kidney, metabolism | Glutathione, metabolism | Nitrites, blood | Benzoquinones, administration and dosage | Catalase, metabolism | Adenosine Triphosphate, metabolism | Lipid Peroxidation, drug effects | Kidney Failure, Acute, prevention and control | Nitrates, metabolism | Kidney Failure, Acute, chemically induced | Nitrates, blood | Nitrites, metabolism | Kidney, pathology | Nigella sativa, chemistry | Gentamicins, administration and dosage | Glutathione Peroxidase, metabolism
Journal Article
Biochemistry, ISSN 0006-2960, 02/2016, Volume 55, Issue 7, pp. 989 - 1002
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2013, Volume 454, Issue 2, pp. 191 - 200
Activity of the aminoglycoside phosphotransferase APH(3')-Ia leads to resistance to aminoglycoside antibiotics in pathogenic Gram-negative bacteria, and... 
Aminoglycoside phosphotransferase APH(3')-Ia | Structure-based drug design | Protein kinase inhibitor | Antibiotic resistance | Crystal structure | structure-based drug design | COMPLEX | MECHANISM | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | aminoglycoside phosphotransferase APH(3 ')-Ia | SENSITIVITY | MODEL | ENZYME | antibiotic resistance | TYROSINE | SUBSTRATE | crystal structure | protein kinase inhibitor | SELECTIVITY | BINDING | Escherichia coli - drug effects | Molecular Conformation | Bacterial Proteins - chemistry | Kanamycin Kinase - metabolism | Isoenzymes - chemistry | Structure-Activity Relationship | Acinetobacter baumannii - enzymology | Pyrimidines - chemistry | Pyrimidines - metabolism | Microbial Sensitivity Tests | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Quinazolines - metabolism | Isoenzymes - metabolism | Drug Design | Escherichia coli - metabolism | Drug Resistance, Bacterial - drug effects | Escherichia coli - growth & development | Binding Sites | Quinazolines - chemistry | Pyrazoles - pharmacology | Recombinant Proteins - metabolism | Bacterial Proteins - antagonists & inhibitors | Recombinant Proteins - antagonists & inhibitors | Anthracenes - chemistry | Isoenzymes - genetics | Recombinant Proteins - chemistry | Pyrazoles - metabolism | Pyrimidines - pharmacology | Kanamycin - pharmacology | Anthracenes - pharmacology | Kanamycin Kinase - antagonists & inhibitors | Kanamycin Kinase - chemistry | Kanamycin - metabolism | Kanamycin Kinase - genetics | Anthracenes - metabolism | Bacterial Proteins - metabolism | Kanamycin - chemistry | Anti-Bacterial Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Aminoglycosides - pharmacology | Quinazolines - pharmacology | Isoenzymes - antagonists & inhibitors | Protein Kinase Inhibitors - metabolism | aminoglycoside phosphotransferase APH(3’)-Ia
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 2014, Volume 58, Issue 8, pp. 4443 - 4451
Journal Article
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7091, pp. 358 - 361
Journal Article