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Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4888 - 4899
Diabetic microvascular complications have been considered to be mediated by a glucose-driven increase in mitochondrial superoxide anion production. Here, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR-BETA | NADPH-OXIDASE | ACTIVATED PROTEIN-KINASE | TRANSFORMING GROWTH-FACTOR-BETA-1 | ENDOTHELIAL-CELLS | MESANGIAL CELLS | SMOOTH-MUSCLE-CELLS | HIGH-GLUCOSE | PYRUVATE-DEHYDROGENASE COMPLEX | MATRIX GENE-EXPRESSION | AMP-Activated Protein Kinases - metabolism | Superoxide Dismutase - genetics | Humans | Male | AMP-Activated Protein Kinases - deficiency | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Kidney - metabolism | Rotenone - pharmacology | Superoxides - metabolism | Mice, Inbred DBA | Diabetes Mellitus, Experimental - metabolism | Superoxide Dismutase - metabolism | Pyruvate Dehydrogenase Complex - metabolism | Diabetic Nephropathies - pathology | Kidney - drug effects | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Superoxide Dismutase - deficiency | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Mice, Knockout | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Diabetes Mellitus, Experimental - pathology | Mice | AMP-Activated Protein Kinases - genetics | Care and treatment | Type 1 diabetes | Physiological aspects | Cyclic adenylic acid | Genetic aspects | Superoxide | Research | Diagnosis | Protein kinases | Studies | Cell culture | Kidneys | Rodents | Storm damage | Software | Diabetes
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2006, Volume 281, Issue 46, pp. 34870 - 34879
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5951, pp. 437 - 440
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2016, Volume 23, Issue 6, pp. 1140 - 1153
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 29, pp. 10574 - 10579
Metformin, a first-line diabetes drug linked to cancer prevention in retrospective clinical analyses, inhibits cellular transformation and selectively kills... 
Lactates | Energy metabolism | Cellular metabolism | Epithelial cells | Cell lines | Stem cells | Glycolysis | Transformed cell line | Breast cancer | Cancer | Metabolic profiling | Cancer metabolism | Metabolism | COMPLEX I | RESPIRATORY-CHAIN | MULTIDISCIPLINARY SCIENCES | glycolysis | metabolic profiling | DECREASES | CHEMOTHERAPY | cancer metabolism | BREAST-CANCER | DIABETIC-PATIENTS | GROWTH | MITOCHONDRIAL DYSFUNCTION | metabolism | INFLAMMATORY RESPONSE | Biguanides - pharmacology | Ribonucleotides - metabolism | Neoplastic Stem Cells - drug effects | Humans | Metformin - pharmacology | Citric Acid Cycle - drug effects | Glycerophosphates - metabolism | Endoplasmic Reticulum - metabolism | Nucleotides - metabolism | Glycolysis - drug effects | Phenformin - pharmacology | Lactates - metabolism | Aminoimidazole Carboxamide - analogs & derivatives | Metabolome - drug effects | Neoplastic Stem Cells - metabolism | Endoplasmic Reticulum - drug effects | Tamoxifen - pharmacology | src-Family Kinases - metabolism | Cell Line, Tumor | Folic Acid - metabolism | Neoplastic Stem Cells - pathology | Aminoimidazole Carboxamide - metabolism | Cell Line, Transformed | Pharmaceutical research | Stem cell research | Analysis | Drug interactions | Cancer cells | Dosage and administration | Metformin | Research | Health aspects | Biological Sciences
Journal Article
Journal Article
Journal Article