X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1409) 1409
Publication (120) 120
Book Chapter (6) 6
Book Review (5) 5
Conference Proceeding (4) 4
Dissertation (4) 4
Book / eBook (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (571) 571
animals (516) 516
male (421) 421
index medicus (394) 394
delta-aminolevulinic-acid (286) 286
biochemistry & molecular biology (263) 263
aminolevulinic acid - metabolism (252) 252
female (251) 251
porphobilinogen synthase - metabolism (233) 233
aminolevulinic acid (220) 220
5-aminolevulinic acid (217) 217
rats (216) 216
adult (194) 194
porphobilinogen synthase - blood (193) 193
heme (184) 184
aminolevulinic acid - urine (182) 182
biosynthesis (177) 177
enzymes (163) 163
heme - biosynthesis (158) 158
aminolevulinic acid - pharmacology (157) 157
lead (150) 150
toxicology (146) 146
photodynamic therapy (144) 144
mice (142) 142
lead - blood (132) 132
5-aminolevulinate synthetase - metabolism (130) 130
middle aged (129) 129
erythrocytes - enzymology (123) 123
aminolevulinic-acid dehydratase (112) 112
oxidative stress (109) 109
expression (102) 102
liver (101) 101
porphyria (98) 98
metabolism (97) 97
liver - metabolism (94) 94
physiological aspects (94) 94
porphobilinogen synthase - genetics (92) 92
porphyrins (89) 89
blood (88) 88
environmental sciences (88) 88
acute intermittent porphyria (86) 86
hydroxymethylbilane synthase - metabolism (82) 82
heme - metabolism (81) 81
porphobilinogen synthase - antagonists & inhibitors (81) 81
proteins (81) 81
escherichia-coli (80) 80
life sciences (80) 80
cancer (79) 79
kinetics (79) 79
pharmacology & pharmacy (79) 79
photochemotherapy (79) 79
δ-aminolevulinic acid dehydratase (79) 79
microbiology (78) 78
research (78) 78
delta-aminolevulinic acid dehydratase (77) 77
gene expression (77) 77
biotechnology & applied microbiology (76) 76
liver - enzymology (75) 75
analysis (74) 74
toxicity (74) 74
mutation (73) 73
exposure (71) 71
liver - drug effects (70) 70
5-aminolevulinate synthetase - genetics (69) 69
lead - toxicity (69) 69
molecular sequence data (69) 69
plant sciences (69) 69
protoporphyrins - blood (69) 69
cell biology (68) 68
porphyrins - metabolism (68) 68
research article (68) 68
inhibition (66) 66
protoporphyrin ix (66) 66
rats, wistar (66) 66
biophysics (65) 65
porphobilinogen deaminase (63) 63
protoporphyrins - metabolism (63) 63
fluorescence (62) 62
oncology (62) 62
porphobilinogen (62) 62
light (61) 61
public, environmental & occupational health (61) 61
gene (59) 59
iron (59) 59
porphobilinogen - urine (58) 58
chlorophyll (57) 57
amino acid sequence (56) 56
time factors (56) 56
porphobilinogen synthase (55) 55
synthase (55) 55
aged (54) 54
environmental exposure (54) 54
photosensitizing agents - pharmacology (54) 54
amino acids (53) 53
blood lead (53) 53
ferrochelatase (53) 53
delta-aminolevulinic acid (52) 52
5-aminolevulinate synthase (51) 51
accumulation (51) 51
acids (51) 51
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1373) 1373
Japanese (32) 32
German (16) 16
Italian (6) 6
Polish (6) 6
French (5) 5
Chinese (4) 4
Spanish (4) 4
Russian (3) 3
Bulgarian (1) 1
Korean (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Structure, ISSN 0969-2126, 04/2018, Volume 26, Issue 4, pp. 580 - 589.e4
5-Aminolevulinic acid synthase (ALAS) catalyzes the first step in heme biosynthesis. We present the crystal structure of a eukaryotic ALAS from Saccharomyces... 
ClpX | AAA+ unfoldase | porphyria | XLSA | XLPP | α-oxoamine family | sideroblastic anemia | BIOCHEMISTRY & MOLECULAR BIOLOGY | LINKED SIDEROBLASTIC ANEMIA | 5-AMINOLEVULINATE SYNTHASE | GLYCINE LOOP | FEATURES | CELL BIOLOGY | PHOSPHATE COFACTOR-BINDING | BIOPHYSICS | METABOLISM | SUCCINYL-COA SYNTHETASE | PURIFICATION | MUTATIONS | DOMINANT PROTOPORPHYRIA | Pyridoxal Phosphate - chemistry | Mitochondria - enzymology | Aminolevulinic Acid - chemistry | Saccharomyces cerevisiae - genetics | Protein Multimerization | Substrate Specificity | Crystallography, X-Ray | Protein Subunits - metabolism | Pyridoxal Phosphate - metabolism | Coenzymes - metabolism | Heme - chemistry | Mitochondria - genetics | Aminolevulinic Acid - metabolism | Heme - biosynthesis | Cloning, Molecular | Escherichia coli - metabolism | 5-Aminolevulinate Synthetase - metabolism | Protein Interaction Domains and Motifs | Coenzymes - chemistry | Mitochondria - chemistry | Protein Subunits - genetics | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Catalytic Domain | Gene Expression | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | 5-Aminolevulinate Synthetase - chemistry | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Saccharomyces cerevisiae - chemistry | Amino Acid Motifs | Protein Conformation, beta-Strand | Escherichia coli - genetics | 5-Aminolevulinate Synthetase - genetics | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae - enzymology | Protein Subunits - chemistry | Kinetics | Mutation | Amino Acid Substitution | Saccharomyces cerevisiae Proteins - chemistry | Phosphates | Enzymes | Anemia | Analysis | Heme | Crystals | Hemoglobin synthesis | Structure | BASIC BIOLOGICAL SCIENCES | ClpXAAA+ unfoldase | AAA+ | unfoldase | Sideroblastic anemia
Journal Article
Molecular Microbiology, ISSN 0950-382X, 12/2018, Volume 110, Issue 6, pp. 1011 - 1029
Summary Strains of the phototrophic alpha‐proteobacterium Rhodobacter sphaeroides vary in the number of enzymes catalyzing the formation of 5‐aminolevulinic... 
SYSTEM | OPERON EXPRESSION | PROTEIN | STRUCTURAL BASIS | CLONING | PROMOTERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELTA-AMINOLEVULINATE SYNTHASE | GENE-EXPRESSION | MICROBIOLOGY | A SYNTHASE | GENOME | Enzymes | Analysis | Dimethyl sulfoxide | Growth conditions | Transcription | Genes | Anaerobic conditions | Feedback inhibition | Genomes | Aminolevulinic acid | Hemin | Acids | Plasmids | Oxidation
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 10/2019, Volume 91, p. 103117
The Figure shows the A-site ALA near the zinc ion, coordinated to three cysteine residues, and P-site ALA juxtaposition to the Schiff-base forming lysine.... 
Catalytic zinc | Schiff base | Tetrapyrroles | Heme | Affinity labeling | MALDI and ESI mass spectrometry | Active site residues | DELTA-AMINOLEVULINIC-ACID | ACTIVE-SITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY-STRUCTURE | ESCHERICHIA-COLI | CHEMISTRY, ORGANIC | SUGGESTS | PSEUDOMONAS-AERUGINOSA | MICROGRAM QUANTITIES | SUBSTRATE | PURIFICATION | INHIBITOR
Journal Article
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 11/2016, Volume 49, Issue 11, pp. 2509 - 2517
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 10/2012, Volume 335, Issue 2, pp. 104 - 112
Journal Article
Biochemistry, ISSN 0006-2960, 09/2015, Volume 54, Issue 36, pp. 5617 - 5631
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 14228 - 13
Journal Article