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Parasite, ISSN 1252-607X, 2011, Volume 18, Issue 3, pp. 207 - 214
Ferroquine (FQ, SSR97193) is currently the most advanced organometallic drug candidate and about to complete phase II clinical trials as a treatment for... 
Resistance | Bioorganometallics | Malaria | Mechanism of action | Drug candidate | Ferroquine | METABOLITES | ferroquine | MECHANISM | FERROCENE | SUSCEPTIBILITY | bioorganometallics | mechanism of action | malaria | drug candidate | CHLOROQUINE | resistance | FERROCHLOROQUINE | PLASMODIUM-FALCIPARUM | DERIVATIVES | IN-VITRO ACTIVITY | PARASITOLOGY | Malaria, Falciparum - drug therapy | Plasmodium vivax - drug effects | Humans | Antimalarials - therapeutic use | Plasmodium falciparum - drug effects | Antimalarials - pharmacology | Chloroquine - pharmacology | Animals | Malaria, Vivax - drug therapy | Ferrous Compounds - pharmacology | Aminoquinolines - chemistry | Antimalarials - chemistry | Chloroquine - chemistry | Ferrous Compounds - chemistry | Ferrous Compounds - therapeutic use | Aminoquinolines - pharmacology | Aminoquinolines - therapeutic use | Drug Resistance | Clinical Trials, Phase II as Topic | Malaria, Vivax/drug therapy | Aminoquinolines/therapeutic use | Plasmodium vivax/drug effects | Biochemistry, Molecular Biology | Chloroquine/pharmacology | Plasmodium falciparum/drug effects | Antimalarials/pharmacology | Malaria, Falciparum/drug therapy | Life Sciences | Ferrous Compounds/chemistry | Ferrous Compounds/pharmacology | Aminoquinolines/pharmacology | Biomolecules | Aminoquinolines/chemistry | Antimalarials/chemistry | Ferrous Compounds/therapeutic use | Antimalarials/therapeutic use | Chloroquine/chemistry | paludisme | candidat médicament | mécanisme d’action | Review | bio-organométallique | résistance
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2009, Volume 52, Issue 5, pp. 1408 - 1415
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 10/2013, Volume 78, Issue 19, pp. 9689 - 9714
The scope of palladium-catalyzed, auxiliary-assisted direct arylation and alkylation of sp2 and sp3 C–H bonds of amine and carboxylic acid derivatives has been... 
Aminoquinolines - chemical synthesis | Hydrogen Bonding | Solvents - chemistry | Aminoquinolines - chemistry | Carboxylic Acids - chemical synthesis | Carboxylic Acids - chemistry | Molecular Structure | Catalysis | Palladium - chemistry | Alkylation
Journal Article
Organic Letters, ISSN 1523-7060, 04/2014, Volume 16, Issue 7, pp. 1840 - 1843
A highly efficient and concise one-pot strategy for the direct amination of quinoline N-oxides via copper-catalyzed dehydrogenative C–N coupling has been... 
FUNCTIONALIZATION | AZOLES | PALLADIUM | ETHERS | INTERMOLECULAR AMINATION | FORMAMIDES | AMINES | AMIDATION | CHLORIDES | CHEMISTRY, ORGANIC | BENZOXAZOLES | Copper - chemistry | Amination | Aminoquinolines - chemical synthesis | Aminoquinolines - chemistry | Oxides - chemistry | Molecular Structure | Catalysis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 21, pp. 8253 - 8258
Autophagy is a lysosome-dependent degradative process that protects cancer cells from multiple stresses. In preclinical models, autophagy inhibition with... 
Cell death | Medical treatment | Cell lines | Lysosomes | Immunoblotting | Cytotoxicity | Dosage | Heterologous transplantation | Tumors | Cancer | Antimalarials | Cancer cell survival | Stress responses | Drug resistance | BISQUINOLINES | cancer cell survival | PROTEIN | cell death | MULTIDISCIPLINARY SCIENCES | TARGETING AUTOPHAGY | MOUSE | antimalarials | TUMOR | CELL-SURVIVAL | stress responses | NECROSIS | drug resistance | CYTOTOXICITY | Autophagy-Related Proteins | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Aminoquinolines - chemical synthesis | Antineoplastic Agents - chemical synthesis | Colonic Neoplasms - drug therapy | Humans | Brain Neoplasms - pathology | Aminoquinolines - toxicity | Drug Resistance, Neoplasm | Polyamines - toxicity | Intestinal Obstruction - chemically induced | Autophagy - drug effects | Antineoplastic Agents - toxicity | Glioblastoma - genetics | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Autophagy - genetics | Cell Death - drug effects | Aminoquinolines - pharmacology | Lysosomes - drug effects | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Adenocarcinoma - drug therapy | Antimalarials - pharmacology | HT29 Cells | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Polyamines - pharmacology | Animals | Mice, Nude | Colonic Neoplasms - pathology | Glioblastoma - pathology | Hydroxychloroquine - pharmacology | Mice | Glioblastoma - drug therapy | Intestinal Obstruction - genetics | Polyamines - chemical synthesis | Autophagy (Cytology) | Phenotype | Genetic aspects | Dosage and administration | Enzyme inhibitors | Identification and classification | Index Medicus | Biological Sciences
Journal Article
Journal Article
Journal of Chromatography B, ISSN 1570-0232, 10/2016, Volume 1033-1034, pp. 117 - 127
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 1560
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2014, Volume 57, Issue 19, pp. 8111 - 8131
Journal Article
Journal Article
Journal Article