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Leukemia, ISSN 0887-6924, 03/2015, Volume 29, Issue 3, pp. 586 - 597
Mutations in the BCR-ABL1 kinase domain are an established mechanism of tyrosine kinase inhibitor (TKI) resistance in Philadelphia chromosome-positive... 
TYROSINE KINASE INHIBITORS | PROGENITOR CELLS | EXCHANGE MASS-SPECTROMETRY | STEM-CELLS | CHRONIC-PHASE | ONCOLOGY | IMATINIB | HEMATOLOGY | LYN KINASE | CANCER-THERAPY | SMALL-MOLECULE INHIBITOR | SIGNAL TRANSDUCER | Leukocytes, Mononuclear - metabolism | Small Molecule Libraries - pharmacology | Phosphorylation | Luciferases - metabolism | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | STAT3 Transcription Factor - chemistry | Luciferases - genetics | Neoplastic Stem Cells - metabolism | Aminosalicylic Acids - chemistry | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Genes, Reporter | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Protein Structure, Tertiary | Dasatinib | Aminosalicylic Acids - pharmacology | Leukocytes, Mononuclear - drug effects | Signal Transduction | Sulfonamides - chemistry | Small Molecule Libraries - chemical synthesis | Gene Expression Regulation, Leukemic | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Drug Discovery | Imatinib Mesylate | Piperazines - pharmacology | Leukocytes, Mononuclear - pathology | Small Molecule Libraries - chemistry | Sulfonamides - chemical synthesis | Fusion Proteins, bcr-abl - genetics | Aminosalicylic Acids - chemical synthesis | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | STAT3 Transcription Factor - antagonists & inhibitors | Fusion Proteins, bcr-abl - metabolism | Drug Resistance, Neoplasm - drug effects | Enzymes | Care and treatment | Genetic aspects | Regulation | Chronic myeloid leukemia | Drug resistance | Health aspects | Index Medicus
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 05/2017, Volume 61, Issue 5
para-Aminosalicylic acid (PAS) is a second-line antituberculosis drug that has been used to treat multidrug-resistant and extensively drug-resistant... 
MYCOBACTERIUM-TUBERCULOSIS | METHOTREXATE | ELIMINATION | MICROBIOLOGY | GENETIC-VARIANTS | antituberculosis drug | ORGANIC CATION TRANSPORTERS | 22 ANTITUBERCULOSIS DRUGS | drug-drug interactions | THERAPY | PHARMACOKINETICS | membrane transporter | RESISTANCE | PHARMACOLOGY & PHARMACY | ANION TRANSPORTER | Octamer Transcription Factor-1 - antagonists & inhibitors | Organic Anion Transport Protein 1 - metabolism | Proton Pump Inhibitors - pharmacology | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Humans | Naproxen - pharmacology | Organic Cation Transporter 2 - antagonists & inhibitors | Organic Cation Transporter 2 - metabolism | Aminosalicylic Acid - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Aminosalicylic Acid - pharmacokinetics | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Biological Transport - drug effects | Cell Line | Organic Anion Transport Protein 1 - antagonists & inhibitors | Ibuprofen - pharmacology | Antitubercular Agents - pharmacology | Probenecid - pharmacology | Quinidine - pharmacology | Verapamil - pharmacology | Antitubercular Agents - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 - antagonists & inhibitors | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | Drug Interactions - physiology | Cimetidine - pharmacology | Aminosalicylic Acid - pharmacology | Biological Transport - physiology | Rifampin - pharmacology | Antitubercular Agents - metabolism | Octamer Transcription Factor-1 - metabolism | Index Medicus
Journal Article
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 09/2014, Volume 5, Issue 1, pp. 4715 - 4715
Breast cancer metastasis involves lymphatic dissemination in addition to hematogenous spreading. Although stromal lymphatic vessels (LVs) serve as initial... 
EPITHELIAL-MESENCHYMAL TRANSITION | TRANSCRIPTION FACTORS | STAT3 ACTIVATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | RESISTANCE | LYMPHANGIOGENESIS | C-JUN | INTERLEUKIN-6 | TUMOR-GROWTH | SIGNAL TRANSDUCER | Neoplasm Transplantation | Interleukin-6 - antagonists & inhibitors | Lymph Nodes - pathology | Cyclohexanes - pharmacology | Humans | Culture Media, Conditioned - pharmacology | Transplantation, Heterologous | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Triple Negative Breast Neoplasms - drug therapy | Vascular Endothelial Growth Factor A - genetics | Chemokine CCL5 - antagonists & inhibitors | Lymphatic Vessels - drug effects | Benzenesulfonates - pharmacology | Lymphatic Vessels - metabolism | MCF-7 Cells | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Triple Negative Breast Neoplasms - pathology | Female | Lymph Nodes - drug effects | Chemokine CCL5 - metabolism | Lung - metabolism | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Gene Expression | Lung - pathology | Aminosalicylic Acids - pharmacology | Human Umbilical Vein Endothelial Cells - drug effects | Interleukin-6 - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Lymph Nodes - metabolism | Antibodies, Neutralizing - pharmacology | Lymphatic Metastasis | Cell Adhesion - drug effects | Triazoles - pharmacology | Cell Movement - drug effects | Animals | Triple Negative Breast Neoplasms - genetics | Mice, Nude | Triple Negative Breast Neoplasms - metabolism | Lung - drug effects | Lymphatic Vessels - pathology | Chemokine CCL5 - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | STAT3 Transcription Factor - antagonists & inhibitors | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2015, Volume 5, Issue 1, pp. 12651 - 12651
Journal Article
Kidney International, ISSN 0085-2538, 08/2010, Volume 78, Issue 3, pp. 257 - 268
Journal Article
Journal Article