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Tetrahedron, ISSN 0040-4020, 05/2014, Volume 70, Issue 18, pp. 3005 - 3010
[4+1] Cycloaddition reaction between isocyanides and N-acylimine derivatives generated from N-acyl N,O-acetals acting as isocyanophiles has been developed.... 
Aminooxazole | Aminothiazole | Isocyanide
Journal Article
by Fu, RG and Wang, Y and Xia, F and Zhang, HL and Sun, Y and Yang, DW and Wang, YW and Yin, P
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 09/2019, Volume 84, Issue 18, pp. 12237 - 12245
A novel one-pot three-component cascade cyclization strategy for the synthesis of 2-amino-5-acylthiazoles using enaminones, cyanamide, and elemental sulfur has... 
DESIGN | AMINOTHIAZOLE DERIVATIVES | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | REDOX CONDENSATION | BOND FORMATION | INHIBITORS | ANTAGONISTS | ACCESS
Journal Article
Inorganic Chemistry Communications, ISSN 1387-7003, 10/2019, Volume 108, p. 107494
Herein, a novel magnetic graphene oxide composite coated by poly(2‑aminothiazole) was synthesized. The nanoadsorbent was characterized with FT-IR, VSM, SEM and... 
Magnetic graphene oxide composite | Cr(VI) | Box-Behnken design | Poly(2‑aminothiazole) | Kinetic studies | Adsorption isotherm
Journal Article
Acta Crystallographica Section E: Structure Reports Online, ISSN 2056-9890, 04/2015, Volume 71, Issue 4, pp. 385 - 387
The title compound, C15H12N2O2S, crystallizes in the ortho-rhom-bic space group Pna21 , with two mol-ecules in the asymmetric unit (Z' = 2). Each mol-ecule... 
Aminobenzothia-zole derivatives | Hydrogen bonding | Aminothiazole Schiff bases | Crystal structure | crystal structure | hydrogen bonding | aminobenzothiazole derivatives | aminothiazole Schiff bases
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2013, Volume 23, Issue 14, pp. 4206 - 4209
ADP receptors, P2Y and P2Y have been recognized as potential targets for antithrombotic drugs. A series of P2Y antagonists that contain 2-aminothiazoles as... 
Platelet aggregation | Aminothiazole as urea surrogates | P2Y1 antagonists | Antithrombotic | antagonists | P2Y | Antagonism
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2015, Volume 56, Issue 2, pp. 472 - 474
A simple methodology was developed to synthesize substituted aminothiazoles from the corresponding thiourea and substituted ketones using aqueous NaICl at... 
Thiourea | Aqueous sodium iodine dichloride (NaICl2) | Ketones | Aminothiazole | ) | Aqueous sodium iodine dichloride (NaICl | Aqueous sodium iodine dichloride | NaICl | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | ANTAGONISTS | THIAZOLES
Journal Article
Journal of Photochemistry & Photobiology, A: Chemistry, ISSN 1010-6030, 11/2017, Volume 348, pp. 246 - 254
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 04/2018, Volume 28, Issue 7, pp. 1178 - 1181
Crystallography has identified stearic acid, ALRT 1550 and ATRA as ligands that bind RORβ, however, none of these molecules represent good starting points to... 
Nuclear receptor | RORβ | Aminothiazole | Selective ligand | CHEMISTRY, MEDICINAL | SCHIZOAFFECTIVE DISORDER | CHEMISTRY, ORGANIC | SCHIZOPHRENIA | ROR beta | RECEPTOR ROR | RETINOIC ACID | CIRCADIAN GENES | MOOD DISORDERS | OSTEOBLASTS | BIPOLAR-I-DISORDER | MICE | ASSOCIATION
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 07/2011, Volume 31, Issue 7, pp. 1136 - 1143
Journal Article
Journal of Molecular Catalysis. A, Chemical, ISSN 1381-1169, 06/2006, Volume 252, Issue 1-2, pp. 235 - 237
A convenient method for the synthesis of thiazoles and aminothiazoles by treatment of phenacyl bromides with thioamides/thiourea in the presence of... 
Ammonium-12-molybdophosphate | Thiourea | Thioamide | Aminothiazole | Thiazole | Phenacyl bromide | ammonium-12-molybdophosphate | PHASE SYNTHESIS | thiourea | phenacyl bromide | ANALOGS | aminothiazole | thiazole | CHEMISTRY, PHYSICAL | thioamide | INHIBITORS | Bromides
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2018, Volume 61, Issue 3, pp. 1061 - 1073
Checkpoint kinase 1 (CHK1) inhibitors are potential cancer therapeutics that can be utilized for enhancing the efficacy of DNA damaging agents. Multiple small... 
DOSE-ESCALATION | POTENT | CHEMISTRY, MEDICINAL | ADVANCED SOLID TUMORS | AZD7762 | DRUG DESIGN | OPTIMIZATION | COMBINATION | PHASE-I | CANCER | PYRIDYL AMINOTHIAZOLES
Journal Article
Journal Article
ACS MEDICINAL CHEMISTRY LETTERS, ISSN 1948-5875, 04/2019, Volume 10, Issue 4, pp. 463 - 468
Small molecule inhibitors of the HIV-1 nucleocapsid protein (NC) are considered as promising agents in the treatment of HIV/AIDS. In an effort to exploit the... 
COMPLEX | CHEMISTRY, MEDICINAL | RECOGNITION | TAR | aminothiazole | STRUCTURAL-CHARACTERIZATION | IDENTIFICATION | antiretroviral | INHIBITION | HIV | drug resistance | Nucleocapsid protein | NC inhibitors | BINDING | PROVIRAL DNA
Journal Article
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