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1. Full Text Efficacy and adverse effects of sotalol in adults with congenital heart disease
by Moore, Benjamin M and Cordina, Rachael L and McGuire, Mark A and Celermajer, David S
International Journal of Cardiology, ISSN 0167-5273, 01/2019, Volume 274, pp. 74 - 79
Adults with congenital heart disease (CHD) are predisposed to arrhythmias, which can often be refractory to medical therapy. Sotalol is an attractive... 
Adult congenital heart disease | Arrhythmias | Sotalol | AMIODARONE | TACHYARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | SAFETY | PROPAFENONE | RISK | ATRIAL-FIBRILLATION | PROFILE | ANTIARRHYTHMIC-DRUGS | Heart | Complications and side effects | Medical colleges | Genetic disorders | Arrhythmia | Analysis | Anti-arrhythmia drugs | Adults | Congenital heart disease
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2. Full Text Electrophysiological Adverse Effects of Direct Acting Antivirals in Patients With Chronic Hepatitis C
by Durante‐Mangoni, Emanuele and Parrella, Antonio and Vitrone, Martina and Rago, Anna and Pafundi, Pia Clara and Nigro, Gerardo and Utili, Riccardo and Russo, Vincenzo
The Journal of Clinical Pharmacology, ISSN 0091-2700, 07/2017, Volume 57, Issue 7, pp. 924 - 930
Recently, several cases of symptomatic, sometimes fatal bradycardia during the first days of direct‐acting antiviral (DAA) (eg, sofosbuvir [SOF])... 
sofosbuvir | direct antiviral agents | arrhythmia | hepatitis C | electrocardiography | AMIODARONE | MARKER | DISPERSION | RISK | RIBAVIRIN | LEDIPASVIR | ATRIAL-FIBRILLATION | TREATMENT-NAIVE | GENOTYPE 1 INFECTION | PHARMACOLOGY & PHARMACY | Sofosbuvir - therapeutic use | Antiviral Agents - pharmacology | Humans | Middle Aged | Risk Factors | Male | Hepatitis C, Chronic - drug therapy | Bradycardia - chemically induced | Electrocardiography | Female | Aged | Sofosbuvir - adverse effects | Cohort Studies | Antiviral agents | Usage | Care and treatment | Electrocardiogram | Electrophysiology | Dosage and administration | Hepatitis C | Cardiac arrhythmia | Hepatitis | Interferon
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3. Full Text Adverse Effects of Low Dose Amiodarone: A Meta-Analysis
by Vorperian, Vicken R and Havighurst, Thomas C and Miller, Stephen and January, Craig T
Journal of the American College of Cardiology, ISSN 0735-1097, 07/1997, Volume 30, Issue 3, pp. 791 - 798
Objectives. We sought to assess the odds of experiencing adverse effects with low dose amiodarone therapy compared with placebo. Background. An estimate of the... 
LONG-TERM AMIODARONE | THREATENING VENTRICULAR ARRHYTHMIAS | K DQ CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC & CARDIOVASCULAR SYSTEMS | PULMONARY TOXICITY | EFFICACY | ACUTE MYOCARDIAL-INFARCTION | DOUBLE-BLIND | REFRACTORY ATRIAL-FIBRILLATION | PLACEBO-CONTROLLED TRIAL | CONGESTIVE-HEART-FAILURE | SINUS RHYTHM | Amiodarone - adverse effects | Anti-Arrhythmia Agents - adverse effects | Humans | Odds Ratio | Anti-Arrhythmia Agents - administration & dosage | Amiodarone - administration & dosage | Randomized Controlled Trials as Topic | Complications and side effects | Analysis | Amiodarone
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4. Full Text Adverse effects of long-term amiodarone therapy
by Park, Hyoung-Seob and Kim, Yoon-Nyun
The Korean Journal of Internal Medicine, ISSN 1226-3303, 09/2014, Volume 29, Issue 5, pp. 571 - 573
KCI Citation Count: 0 
MEDICINE, GENERAL & INTERNAL | METAANALYSIS | Amiodarone - adverse effects | Female | Male | Anti-Arrhythmia Agents - adverse effects | Humans | 내과학
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5. Full Text Adverse effects of amiodarone therapy in adults with congenital heart disease
by Moore, Benjamin M and Cordina, Rachael L and McGuire, Mark A and Celermajer, David S
Congenital Heart Disease, ISSN 1747-079X, 11/2018, Volume 13, Issue 6, pp. 944 - 951
Objective Amiodarone is a highly effective antiarrhythmic therapy, however its toxicity profile often limits treatment. This is particularly relevant in adults... 
adverse effects | amiodarone | arrhythmia | efficacy | ARRHYTHMIAS | TACHYARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | MANAGEMENT | THYROID-DYSFUNCTION | PROPAFENONE | EFFECTIVE ANTIARRHYTHMIC-DRUG | SOTALOL | YOUNG | Index Medicus
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6. Full Text Endocrine disruption as an adverse effect of non-endocrine targeting pharmaceuticals
by Sabir, Shakila and Akhtar, Muhammad Furqan and Saleem, Ammara
Environmental Science and Pollution Research, ISSN 0944-1344, 1/2019, Volume 26, Issue 2, pp. 1277 - 1286
Endocrine disruptors have gained widespread attention owing to their severe adverse health impacts. These produce enormous burden of disease and are associated... 
Testis | Environmental Health | Ecotoxicology | Environment, general | Medicine | Ovary | Environment | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Diabetes | Pancreas | Environmental Chemistry | Atmospheric Protection/Air Quality Control/Air Pollution | Thyroid | ACETYLSALICYLIC-ACID | RISK-FACTORS | THYROID-DYSFUNCTION | ATYPICAL ANTIPSYCHOTICS | DIABETES-MELLITUS | ENVIRONMENTAL SCIENCES | WEIGHT-GAIN | ANTIEPILEPTIC DRUGS | LITHIUM | AMIODARONE-INDUCED THYROTOXICOSIS | INTERFERON THERAPY | Developed countries | Endocrine disruptors | Drugs | Neuroleptics | Packaging materials | Toxicity | Food packaging | Thyroid gland | Drug resistance | Drug development | Food waste | Antitumor agents | Industrial wastes | Thyroxine | Triiodothyronine | Polymers | Pollutants | Iodine | Antiviral agents | Reproductive systems | Diabetes mellitus | Pesticides | Food production | Insulin | Side effects | Packaging | Thyrocytes | Reproductive system | Disruption | Health risk assessment | Pharmaceuticals | Index Medicus
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7. Full Text “Blue-grey syndrome” – A rare adverse effect of amiodarone
by Kuncipálová, Hana and Toušek, František and Janatová, Hana and Přádná, Jana and Řežábek, Miroslav
Cor et Vasa, ISSN 0010-8650, 12/2018, Volume 60, Issue 6, pp. e638 - e644
Amiodarone is a very effective drug for some patients in cardiology, we must always consider its frequent adverse effects, which can significantly affect the... 
Amiodarone | Adverse effects | Blue-grey syndrome
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8. Full Text Liposomal Amiodarone Augments Anti-arrhythmic Effects and Reduces Hemodynamic Adverse Effects in an Ischemia/Reperfusion Rat Model
by Takahama, Hiroyuki and Shigematsu, Hirokazu and Asai, Tomohiro and Matsuzaki, Takashi and Sanada, Shoji and Fu, Hai Ying and Okuda, Keiji and Yamato, Masaki and Asanuma, Hiroshi and Asano, Yoshihiro and Asakura, Masanori and Oku, Naoto and Komuro, Issei and Kitakaze, Masafumi and Minamino, Tetsuo
Cardiovascular Drugs and Therapy, ISSN 0920-3206, 4/2013, Volume 27, Issue 2, pp. 125 - 132
Although amiodarone is recognized as the most effective anti-arrhythmic drug available, it has negative hemodynamic effects. Nano-sized liposomes can... 
Lethal arrhythmia | Reperfusion | Medicine & Public Health | Ischemia | Liposome | Amiodarone | Cardiology | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | DRUG-DELIVERY | INJURY | ADENOSINE | DEATH | VENTRICULAR-ARRHYTHMIAS | PHARMACOLOGY & PHARMACY | DESETHYLAMIODARONE | Rats, Wistar | Anti-Arrhythmia Agents - blood | Rats | Male | Amiodarone - blood | Anti-Arrhythmia Agents - pharmacokinetics | Anti-Arrhythmia Agents - administration & dosage | Arrhythmias, Cardiac - physiopathology | Myocardial Reperfusion Injury - physiopathology | Amiodarone - administration & dosage | Arrhythmias, Cardiac - drug therapy | Animals | Amiodarone - pharmacokinetics | Arrhythmias, Cardiac - blood | Hemodynamics - drug effects | Nanoparticles - administration & dosage | Liposomes | Myocardial Reperfusion Injury - drug therapy | Myocardial Reperfusion Injury - blood | Disease Models, Animal | Drugs | Thin films | Complications and side effects | Drug delivery systems | Heart beat | Arrhythmia | Mortality | Universities and colleges | Dielectric films | Vehicles
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9. Full Text Increased frequency of cytochrome P450 2D6 poor metabolizers among patients with metoprolol-associated adverse effects
by Wuttke, Henrike and Rau, Thomas and Heide, Roland and Bergmann, Klaus and Böhm, Michael and Weil, Joachim and Werner, Dierk and Eschenhagen, Thomas
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 10/2002, Volume 72, Issue 4, pp. 429 - 437
Objective The CYP2D6 genotype is a major determinant of interindividual differences in metoprolol plasma clearance. Cytochrome P450 2D6 (CYP2D6) poor... 
OXIDATION | ALLELE | SPARTEINE | AMIODARONE | DEXTROMETHORPHAN | PHENOTYPE | PHARMACOLOGY & PHARMACY | POLYMORPHISM | CYP2D6 GENOTYPE | DEBRISOQUINE | DRUG-INTERACTION | Cytochrome P-450 CYP2D6 - genetics | Humans | Middle Aged | Genotype | Male | Metoprolol - adverse effects | Chi-Square Distribution | Statistics, Nonparametric | Cytochrome P-450 CYP2D6 - metabolism | Adult | Female | Aged | Gene Frequency - drug effects | Metoprolol - blood | Retrospective Studies | Cohort Studies
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10. Adverse effects of amiodarone therapy in adults with congenital heart disease
by Moore, Benjamin M and Cordina, Rachael L and McGuire, Mark A and Celermajer, David S
Congenital heart disease, 11/2018, Volume 13, Issue 6, p. 944
Amiodarone is a highly effective antiarrhythmic therapy, however its toxicity profile often limits treatment. This is particularly relevant in adults with... 
Follow-Up Studies | Risk Assessment | Comorbidity | Humans | Middle Aged | Male | Drug-Related Side Effects and Adverse Reactions - epidemiology | Young Adult | Amiodarone - adverse effects | Arrhythmias, Cardiac - drug therapy | Heart Defects, Congenital - complications | Anti-Arrhythmia Agents - adverse effects | Adolescent | Adult | Female | Aged | Arrhythmias, Cardiac - complications | Retrospective Studies | New South Wales - epidemiology
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11. Full Text The calcium–phosphate balance, modulation of thyroid autoimmune processes and other adverse effects connected with thyroid arterial embolization
by Kaminski, Grzegorz and Jaroszuk, Andrzej and Zybek, Ariadna and Brzozowski, Krzysztof and Piasecki, Piotr and Ziecina, Piotr and Ruchala, Marek
Endocrine, ISSN 1355-008X, 6/2014, Volume 46, Issue 2, pp. 292 - 299
In search of new treatment options for thyroid diseases, when conventional procedures are ineffective, contraindicated or associated with serious side effects,... 
Thyroid autoimmunity | Side effects | Medicine & Public Health | Thyroid embolization | Thyroid diseases | Internal Medicine | Diabetes | Calcium–phosphate balance | Endocrinology | Science, general | Calcium-phosphate balance | SURGERY | PREOPERATIVE EMBOLIZATION | ANTITHYROID DRUGS | RADIOIODINE THERAPY | POSTOPERATIVE COMPLICATIONS | OPHTHALMOPATHY | ENDOCRINOLOGY & METABOLISM | GRAVES-DISEASE | PATIENT | AMIODARONE-INDUCED THYROTOXICOSIS | CARCINOMA | Autoimmunity | Graves Disease - blood | Humans | Middle Aged | Male | Young Adult | Calcium - blood | Goiter - blood | Graves Disease - immunology | Thyroid Hormones - blood | Aged, 80 and over | Phosphates - blood | Adult | Female | Thyroid Gland - immunology | Embolization, Therapeutic - methods | Hyperthyroidism - blood | Hyperthyroidism - therapy | Treatment Outcome | Hyperthyroidism - immunology | Graves Disease - therapy | Goiter - therapy | Adolescent | Goiter - immunology | Aged | Complications and side effects | Care and treatment | Therapeutic embolization | Patient outcomes | Calcium phosphate | Research | Index Medicus | Original
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12. Full Text A Screening Study of Drug–Drug Interactions in Cerivastatin Users: An Adverse Effect of Clopidogrel
by Floyd, J S and Kaspera, R and Marciante, K D and Weiss, N S and Heckbert, S R and Lumley, T and Wiggins, K L and Tamraz, B and Kwok, P‐Y and Totah, R A and Psaty, B M
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 05/2012, Volume 91, Issue 5, pp. 896 - 904
An analysis of a case–control study of rhabdomyolysis was conducted to screen for previously unrecognized cytochrome P450 enzyme (CYP) 2C8 inhibitors that may... 
GEMFIBROZIL | CYP2C8 | COA REDUCTASE INHIBITORS | METABOLISM | PLASMA-CONCENTRATIONS | CYP3A4 IN-VITRO | AMIODARONE N-DEETHYLATION | PHARMACOLOGY & PHARMACY | FLUOXYMESTERONE | RHABDOMYOLYSIS | PREDICTION | Cytochrome P-450 CYP2C8 | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Adverse Drug Reaction Reporting Systems | Cytochrome P-450 CYP3A | Humans | Male | Case-Control Studies | Ticlopidine - analogs & derivatives | Pyridines - adverse effects | Cytochrome P-450 CYP3A Inhibitors | Drug Interactions | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Pyridines - metabolism | Ticlopidine - adverse effects | Aged, 80 and over | Rhabdomyolysis - chemically induced | Clopidogrel | Female | Aged | Platelet Aggregation Inhibitors - adverse effects | Usage | Research | Drug interactions | clopidogrel | rhabdomyolysis | adverse drug reaction | statins | acyl glucuronide | drug-drug interaction prediction | 2-oxo-clopidogrel
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13. Full Text Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect?
by Schwaiblmair, Martin and Berghaus, Thomas and Haeckel, Thomas and Wagner, Theodor and von Scheidt, Wolfgang
Clinical Research in Cardiology, ISSN 1861-0684, 11/2010, Volume 99, Issue 11, pp. 693 - 700
Several forms of pulmonary disease occur among patients treated with amiodarone, i.e. chronic interstitial pneumonitis, organizing pneumonia, ARDS, a solitary... 
Amiodarone | Medicine & Public Health | Cardiology | Pulmonary toxicity | Adverse effect | CARDIAC & CARDIOVASCULAR SYSTEMS | INTRAVENOUS AMIODARONE | LOW-DOSE AMIODARONE | ATRIAL-FIBRILLATION | INTERSTITIAL PNEUMONITIS | PATHOGENESIS | THERAPY | DRONEDARONE | CONGESTIVE-HEART-FAILURE | INDUCED LUNG-DISEASE | ORGANIZING PNEUMONIA | Severity of Illness Index | Amiodarone - adverse effects | Arrhythmias, Cardiac - drug therapy | Anti-Arrhythmia Agents - adverse effects | Pneumonia - chemically induced | Drug-Related Side Effects and Adverse Reactions | Humans | Risk Factors | Pulmonary Fibrosis - chemically induced | Lung Injury - chemically induced | Complications and side effects | Pneumonia | Corticosteroids | Bacterial pneumonia | Pulmonary function tests | Carbon monoxide | Index Medicus
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14. Full Text "Blue-grey syndrome" - A rare adverse effect of amiodarone
by Kuncipálová, Hana and Toušek, František and Janatová, Hana and Přádná, Jana and Řežábek, Miroslav
Cor et Vasa, ISSN 0010-8650, 12/2018, Volume 60, Issue 6, pp. e638 - e644
Amiodarone is a very effective drug for some patients in cardiology, we must always consider its frequent adverse effects, which can significantly affect the... 
Complications and side effects | Amiodarone | Dosage and administration | Pigmentation disorders | Risk factors
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15. Full Text Adverse Effects of Intravenous Amiodarone in 5 Dogs
by Cober, R.E and Schober, K.E and Hildebrandt, N and Sikorska, E and Riesen, S.C
Journal of Veterinary Internal Medicine, ISSN 0891-6640, 05/2009, Volume 23, Issue 3, pp. 657 - 661
HYPOTENSIVE ACTION | AQUEOUS FORMULATION | RECURRENT | TACHYCARDIA | VETERINARY SCIENCES | VENTRICULAR TACHYARRHYTHMIAS | POLYSORBATE-80 | HEALTHY DOGS | BLOOD-PRESSURE | ATRIAL-FIBRILLATION | Injections, Intravenous | Heart Diseases - veterinary | Male | Anti-Arrhythmia Agents - therapeutic use | Anaphylaxis - veterinary | Anti-Arrhythmia Agents - administration & dosage | Amiodarone - administration & dosage | Amiodarone - adverse effects | Animals | Dog Diseases - drug therapy | Amiodarone - therapeutic use | Anaphylaxis - chemically induced | Anti-Arrhythmia Agents - adverse effects | Dogs | Female | Heart Diseases - drug therapy | Dog Diseases - chemically induced | Index Medicus
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16. Full Text Developing a list of high-alert medications for patients with chronic diseases
by Otero, María José and Moreno-Gómez, Ana María and Santos-Ramos, Bernardo and Agra, Yolanda
European Journal of Internal Medicine, ISSN 0953-6205, 2014, Volume 25, Issue 10, pp. 900 - 908
Abstract Background Patients with chronic diseases often receive multiple medications and are associated with increased vulnerability to medication errors.... 
Internal Medicine | Safety management/organization and administration | High-alert medications | Patient safety | Chronic patient | Medication errors/prevention and control | EMERGENCY-DEPARTMENT VISITS | HOSPITAL ADMISSIONS | UNIT | ADVERSE DRUG EVENTS | SAFETY | RISK | PREVALENCE | CARE | OLDER PERSONS | MEDICINE, GENERAL & INTERNAL | PRESCRIPTIONS | Digoxin - adverse effects | Drug-Related Side Effects and Adverse Reactions - prevention & control | Antipsychotic Agents - adverse effects | Humans | Sodium Potassium Chloride Symporter Inhibitors - adverse effects | Mineralocorticoid Receptor Antagonists - adverse effects | Amiodarone - analogs & derivatives | Adrenal Cortex Hormones - adverse effects | Amiodarone - adverse effects | Cytostatic Agents - adverse effects | Methotrexate - adverse effects | Analgesics, Opioid - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anticonvulsants - adverse effects | Anti-Arrhythmia Agents - adverse effects | Adrenergic beta-Antagonists - adverse effects | Immunosuppressive Agents - adverse effects | Benzodiazepines - adverse effects | Spironolactone - analogs & derivatives | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Spironolactone - adverse effects | Chronic Disease - drug therapy | Platelet Aggregation Inhibitors - adverse effects | Drugs | Chronic diseases
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