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1. Full Text Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis
by Cooper, Christopher J and Murphy, Timothy P and Cutlip, Donald E and Jamerson, Kenneth and Henrich, William and Reid, Diane M and Cohen, David J and Matsumoto, Alan H and Steffes, Michael and Jaff, Michael R and Prince, Martin R and Lewis, Eldrin F and Tuttle, Katherine R and Shapiro, Joseph I and Rundback, John H and Massaro, Joseph M and D'Agostino, Ralph B and Dworkin, Lance D and Coral Investigators and CORAL Investigators
The New England Journal of Medicine, ISSN 0028-4793, 01/2014, Volume 370, Issue 1, pp. 13 - 22
In this trial, 947 patients with renal-artery stenosis were assigned to renal-artery stenting or medical therapy. At a median of 43 months, there was no... 
MEDICINE, GENERAL & INTERNAL | REVASCULARIZATION | SYSTOLIC BLOOD-PRESSURE | PLACEMENT | PREVENTION | BALLOON ANGIOPLASTY | PREVALENCE | HYPERTENSION | Follow-Up Studies | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Hypertension - drug therapy | Male | Renal Insufficiency, Chronic - complications | Renal Artery | Treatment Failure | Cardiovascular Diseases - mortality | Female | Angioplasty, Balloon | Pyrroles - therapeutic use | Stents | Cardiovascular Diseases - etiology | Renal Artery Obstruction - drug therapy | Kaplan-Meier Estimate | Combined Modality Therapy | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Renal Artery Obstruction - complications | Anticholesteremic Agents - therapeutic use | Hypertension - complications | Aged | Renal Artery Obstruction - therapy | Drug Combinations | Prevention | Evaluation | Care and treatment | Usage | Atherosclerosis | Therapeutics | Stent (Surgery) | Homeopathy | Materia medica and therapeutics | Hypertension | Myocardial infarction | Cerebral infarction | Stroke | Kidneys | Renal artery | Medical treatment | Clinical trials | Stenosis | Cardiovascular disease | Congestive heart failure | Renal insufficiency | Arteriosclerosis | Implants | Renal failure | Blood pressure | Kidney diseases | Geriatrics
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2. Full Text Effect of PCI on Quality of Life in Patients with Stable Coronary Disease
by Weintraub, William S and Spertus, John A and Kolm, Paul and Maron, David J and Zhang, Zefeng and Zhang, Wei and Jurkovitz, Claudine and Hartigan, Pamela M and Lewis, Cheryl and Veledar, Emir and Bowen, Jim and Dunbar, Sandra B and Deaton, Christi and Kaufman, Stanley and O'Rourke, Robert A and Goeree, Ron and Barnett, Paul G and Teo, Koon K and Boden, William E and COURAGE Trial Res Grp and COURAGE Trial Research Group
The New England Journal of Medicine, ISSN 0028-4793, 08/2008, Volume 359, Issue 7, pp. 677 - 687
In the COURAGE trial, percutaneous coronary intervention (PCI), added to optimal medical therapy, did not reduce the subsequent rate of death or myocardial... 
MEDICINE, GENERAL & INTERNAL | REVASCULARIZATION | EVALUATION COURAGE TRIAL | ANGIOPLASTY | MEDICAL THERAPY | ANGINA | RITA-2 TRIAL | OUTCOMES | INTERVENTION | ARTERY-DISEASE | HEALTH-STATUS | Ticlopidine - therapeutic use | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Male | Angina Pectoris - etiology | Angina Pectoris - psychology | Angioplasty, Balloon, Coronary | Patient Satisfaction | Coronary Disease - complications | Female | Surveys and Questionnaires | Aspirin - therapeutic use | Isosorbide Dinitrate - therapeutic use | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Stents | Adrenergic beta-Antagonists - therapeutic use | Angina Pectoris - drug therapy | Metoprolol - therapeutic use | Combined Modality Therapy | Angina Pectoris - therapy | Ticlopidine - analogs & derivatives | Amlodipine - therapeutic use | Cross-Over Studies | Coronary Disease - therapy | Quality of Life | Health Status | Transluminal angioplasty | Care and treatment | Coronary heart disease | Health aspects | Unstable angina | Risk factors | Medical research | Cardiovascular disease | Heart attacks | Angina pectoris | Coronary vessels
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3. Full Text Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients
by Jamerson, Kenneth and Weber, Michael A and Bakris, George L and Dahlöf, Björn and Pitt, Bertram and Shi, Victor and Hester, Allen and Gupte, Jitendra and Gatlin, Marjorie and Velazquez, Eric J and ACCOMPLISH Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 12/2008, Volume 359, Issue 23, pp. 2417 - 2428
The optimal combination drug therapy for treatment of hypertension is not established, although current U.S. guidelines recommend inclusion of a diuretic. This... 
SYSTOLIC HYPERTENSION | ACE-INHIBITORS | MEDICINE, GENERAL & INTERNAL | ACCOMPLISH TRIAL | COMBINATION THERAPY | AVOIDING CARDIOVASCULAR EVENTS | NITRIC-OXIDE | BLOOD-PRESSURE | Benzazepines - adverse effects | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Male | Risk | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Blood Pressure - drug effects | Drug Therapy, Combination | Hydrochlorothiazide - adverse effects | Double-Blind Method | Kaplan-Meier Estimate | Amlodipine - adverse effects | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Antihypertensive Agents - adverse effects | Benzazepines - therapeutic use | Diuretics - therapeutic use | Aged | Hydrochlorothiazide - therapeutic use | Hypertension | Prevention | Care and treatment | Usage | Benazepril | Cardiovascular diseases | Health aspects | Comparative studies | Clinical trials | Pharmacology | Calcium | ACE inhibitors | Index Medicus | Abridged Index Medicus
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4. Full Text Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension
by de la Sierra, Alejandro and Armario, Pedro and Oliveras, Anna and Banegas, José R and Gorostidi, Manuel and Vinyoles, Ernest and de la Cruz, Juan J and Segura, Julián and Ruilope, Luis M
Journal of Hypertension, ISSN 0263-6352, 07/2018, Volume 36, Issue 7, pp. 1563 - 1570
BACKGROUND AND AIM:Treatment-resistant hypertension (TRH) is associated with particular clinical features, nonadherence, and suboptimal treatment. We assessed... 
ambulatory blood pressure monitoring | antihypertensive drugs | combination therapy | blood pressure control | resistant hypertension | UNITED-STATES | METAANALYSIS | PREVALENCE | CHLORTHALIDONE | ADHERENCE | HYDROCHLOROTHIAZIDE | TRIAL | OFFICE BLOOD-PRESSURE | SPIRONOLACTONE | DOUBLE-BLIND | PERIPHERAL VASCULAR DISEASE | Blood Pressure | Chlorthalidone - therapeutic use | Bisoprolol - therapeutic use | Humans | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Antihypertensive Agents - therapeutic use | Hypertension - physiopathology | Amlodipine - therapeutic use | Mineralocorticoid Receptor Antagonists - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Diuretics - therapeutic use | Tetrazoles - therapeutic use | Imidazoles - therapeutic use | Ramipril - therapeutic use | Drug Therapy, Combination | Angiotensin Receptor Antagonists - therapeutic use | Drug Resistance | Hypertension | Antihypertensive drugs | Care and treatment | Control | Dosage and administration | Blood pressure
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5. Full Text Effects of β blockers and calcium-channel blockers on within-individual variability in blood pressure and risk of stroke
by Rothwell, Peter M, FMedSci and Howard, Sally C, DPhil and Dolan, Eamon, MRCP and O'Brien, Eoin, FRCP and Dobson, Joanna E, MSc and Dahlöf, Bjorn, MD and Poulter, Neil R, FMedSci and Sever, Peter S, FRCP and ASCOT-BPLA MRC Trial Invest and ASCOT-BPLA and MRC Trial Investigators and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Lancet Neurology, The, ISSN 1474-4422, 2010, Volume 9, Issue 5, pp. 469 - 480
Summary Background Analyses of some randomised trials show that calcium-channel blockers reduce the risk of stroke more than expected on the basis of mean... 
Neurology | CARDIOVASCULAR EVENTS | TRANSIENT ISCHEMIC ATTACK | SOCIETY-OF-HYPERTENSION | REGRESSION DILUTION | TO-VISIT VARIABILITY | ORGAN DAMAGE | ARTERY FUNCTION EVALUATION | OUTCOMES | CORONARY-HEART-DISEASE | LOWERING DRUGS | CLINICAL NEUROLOGY | Stroke - prevention & control | Prospective Studies | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Male | Risk | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Atenolol - therapeutic use | Adult | Female | Aged | Blood Pressure - drug effects | Blood Pressure Monitoring, Ambulatory | Adrenergic beta-Antagonists - therapeutic use | MEDICIN OCH HÄLSOVETENSKAP | MEDICAL AND HEALTH SCIENCES
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6. Full Text Effects of Ranolazine With Atenolol, Amlodipine, or Diltiazem on Exercise Tolerance and Angina Frequency in Patients With Severe Chronic Angina: A Randomized Controlled Trial
by Chaitman, Bernard R and Pepine, Carl J and Parker, John O and Skopal, Jaroslav and Chumakova, Galina and Kuch, Jerzy and Wang, Whedy and Skettino, Sandra L and Wolff, Andrew A and for the Combination Assessment of Ranolazine In Stable Angina (CARISA) Investigators and CARISA Investigators and Combination Assessment of Ranolazine In Stable Angina (CARISA) Investigators
JAMA, ISSN 0098-7484, 01/2004, Volume 291, Issue 3, pp. 309 - 316
CONTEXT Many patients with chronic angina experience anginal episodes despite revascularization and antianginal medications. In a previous trial, antianginal... 
RAT HEARTS | STABLE ANGINA | MEDICINE, GENERAL & INTERNAL | PECTORIS | CLINICAL-TRIALS | DISEASE | DOUBLE-BLIND | SAMPLE-SIZE REESTIMATION | OUTCOMES | COMBINATION | BURDEN | Angina Pectoris - physiopathology | Physical Exertion - physiology | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Male | Physical Exertion - drug effects | Myocardial Ischemia | Ranolazine | Exercise Test | Electrocardiography | Female | Drug Therapy, Combination | Acetanilides | Adrenergic beta-Antagonists - therapeutic use | Double-Blind Method | Nitroglycerin - therapeutic use | Angina Pectoris - drug therapy | Piperazines - therapeutic use | Amlodipine - therapeutic use | Cardiovascular Agents - therapeutic use | Atenolol - therapeutic use | Diltiazem - therapeutic use | Survival Analysis | Aged | Hemodynamics | Chronic Disease | Angina pectoris | Biological products industry | Clinical trials | Drug testing | Medical treatment
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7. Full Text Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: Principal results of the Conduit Artery Function Evaluation (CAFE) study
by Williams, Bryan and Lacy, Peter S and Thom, Simon M and Cruickshank, Kennedy and Stanton, Alice and Collier, David and Hughes, Alun D and Thurston, H and O'Rourke, Michael and CAFE Investigators ASCOT Investiga and CAFE Steering Committee and Writing Committee and Anglo-Scandinavian Cardiac Outcomes Trial Investigators and CAFE Investigators and The CAFE Investigators
Circulation, ISSN 0009-7322, 03/2006, Volume 113, Issue 9, pp. 1213 - 1225
Background - Different blood pressure (BP)-lowering drugs could have different effects on central aortic pressures and thus cardiovascular outcome despite... 
Hypertension | Aorta | Blood pressure | Hemodynamics | Arteries | blood pressure | PULSE-WAVE ANALYSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | arteries | RANDOMIZED CONTROLLED-TRIAL | CARDIAC NATRIURETIC PEPTIDES | hemodynamics | LEFT-VENTRICULAR HYPERTROPHY | ARM ASCOT-BPLA | LOW-DOSE COMBINATION | END-POINT REDUCTION | CONVERTING-ENZYME-INHIBITOR | ANGIOTENSIN RECEPTOR ANTAGONIST | PERIPHERAL VASCULAR DISEASE | aorta | ESSENTIAL-HYPERTENSION | HEMATOLOGY | hypertension | Antihypertensive Agents - pharmacology | Cardiovascular Diseases | Age Distribution | Humans | Middle Aged | Hypertension - drug therapy | Male | Treatment Outcome | Sodium Chloride Symporter Inhibitors - therapeutic use | Antihypertensive Agents - therapeutic use | Sodium Chloride Symporter Inhibitors - pharmacology | Amlodipine - therapeutic use | Perindopril - pharmacology | Atenolol - therapeutic use | Renal Insufficiency | Amlodipine - pharmacology | Hypertension - complications | Brachial Artery - physiopathology | Female | Blood Pressure - drug effects | Aorta - physiopathology | Drug Therapy, Combination | Perindopril - therapeutic use | Atenolol - pharmacology
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8. Full Text Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
by The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group and ALLHAT Collaborative Res Grp and ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
JAMA, ISSN 0098-7484, 12/2002, Volume 288, Issue 23, pp. 2981 - 2997
CONTEXT Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal first-step therapy is unknown.... 
MORTALITY | GLOMERULAR-FILTRATION-RATE | MEDICINE, GENERAL & INTERNAL | THERAPY | DISEASE | FAILURE | CHLORTHALIDONE | BLOOD-PRESSURE | AFRICAN-AMERICAN | PROGRESSION | PARTICIPANTS | Diuretics - economics | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Lisinopril - economics | Hypertension - drug therapy | Male | Angiotensin-Converting Enzyme Inhibitors - economics | Lisinopril - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Cardiovascular Diseases - epidemiology | Female | Calcium Channel Blockers - economics | Antihypertensive Agents - economics | Chlorthalidone - therapeutic use | Double-Blind Method | Risk Factors | Chlorthalidone - economics | Proportional Hazards Models | Treatment Outcome | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Diuretics - therapeutic use | Aged | Amlodipine - economics | Hypertension | Diuretics | Evaluation | Cookery for hypertensives | Drug therapy | Thiazides | Prevention | Enzymes | Neurotransmitters | Heart attacks | Clinical trials | Lipids | Health risk assessment | Patients | Clinical outcomes
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