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Molecular Pharmacology, ISSN 0026-895X, 03/2008, Volume 73, Issue 3, pp. 789 - 800
In addition to being an important receptor in leukocyte activation and mobilization, CCR5 is the essential coreceptor for human immunodeficiency virus (HIV). A... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Anti-HIV Agents - pharmacology | Benzoates - metabolism | Humans | Receptors, CCR5 - genetics | Piperazines - chemistry | Pyrimidines - metabolism | Receptors, CCR5 - metabolism | Piperidines - pharmacology | Amides - metabolism | Anti-HIV Agents - metabolism | Radioligand Assay | Binding Sites | Amides - pharmacology | Anti-HIV Agents - classification | Amino Acid Sequence | Piperidines - metabolism | Models, Molecular | Pyrimidines - pharmacology | HIV Fusion Inhibitors - pharmacology | Piperazines - pharmacology | Triazoles - metabolism | Anti-HIV Agents - chemistry | Amides - chemistry | Benzoates - pharmacology | Hydrophobic and Hydrophilic Interactions | Receptors, CCR5 - chemistry | Quaternary Ammonium Compounds - pharmacology | Cricetulus | Triazoles - chemistry | Benzoates - chemistry | Cyclohexanes - pharmacology | Molecular Sequence Data | Piperazines - metabolism | Quaternary Ammonium Compounds - chemistry | Pyrimidines - chemistry | Cyclohexanes - metabolism | Transfection | Inhibitory Concentration 50 | Cyclohexanes - chemistry | Molecular Structure | Membrane Fusion - drug effects | Spiro Compounds - chemistry | CCR5 Receptor Antagonists | CHO Cells | Protein Structure, Tertiary | Cricetinae | Piperidines - chemistry | Mutagenesis, Site-Directed | Protein Structure, Secondary | HIV-1 - drug effects | Static Electricity | Sequence Homology, Amino Acid | Triazoles - pharmacology | Animals | Quaternary Ammonium Compounds - metabolism | Spiro Compounds - pharmacology | Spiro Compounds - metabolism | Index Medicus
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 01/2011, Volume 250, Issue 2, pp. 108 - 116
There is evidence from both epidemiology and laboratory studies that perfluorinated compounds may be immunotoxic, affecting both cell-mediated and humoral immunity... 
PPAR-α receptor | Immunosuppression | Perfluorinated compounds | MMP-9 | Whole blood assay | Cytokine | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Fluorocarbons - toxicity | PPAR alpha - drug effects | Alkanesulfonic Acids - immunology | Caprylates - toxicity | Cytokines - metabolism | Humans | Interferon-gamma - drug effects | Interferon-gamma - metabolism | Fluorocarbons - immunology | Interleukins - metabolism | Lipopolysaccharides | Leukocytes - immunology | Caprylates - immunology | Matrix Metalloproteinase 9 - metabolism | Tumor Necrosis Factor-alpha - drug effects | Cytokines - drug effects | Inflammation Mediators - metabolism | Cell Line, Tumor | Matrix Metalloproteinase 9 - drug effects | Leukocytes - drug effects | Alkanesulfonic Acids - toxicity | PPAR alpha - metabolism | Leukocytes - metabolism | Immunotherapy | Ammonium perfluorooctanoate | Index Medicus | Cell culture | Cytokines | Immunomodulation | Immunotoxicity | Inflammation | Lymphocytes T | siRNA | Leukocytes | Gene expression | Epidemiology | Gelatinase B | Immunity (cell-mediated) | Fenofibrate | Interleukin 6 | Interleukin 4 | Interleukin 10 | Peripheral blood | Hemagglutinins | gamma -Interferon | Immunity (humoral) | Interleukin 8 | Tumor necrosis factor- alpha | HUMAN POPULATIONS | BODY FLUIDS | BIOLOGICAL MATERIALS | ORGANIC COMPOUNDS | MITOGENS | POPULATIONS | 60 APPLIED LIFE SCIENCES | GROWTH FACTORS | LEUKOCYTES | LYMPHOKINES | IMMUNOSUPPRESSION | IN VITRO | BLOOD CELLS | PROTEINS | MATERIALS | EPIDEMIOLOGY | BLOOD
Journal Article
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 2010, Volume 245, Issue 3, pp. 326 - 334
Oxidative stress has been proposed as an important promoter of the progression of fatty liver diseases. The current study investigates the potential functions... 
MCD diet | Fatty liver disease | Mouse | Nrf2 | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Liver - pathology | Body Weight | Cytoskeletal Proteins - genetics | Fatty Liver - pathology | Glutathione - metabolism | Choline Deficiency - complications | Male | RNA, Messenger - metabolism | Cytoskeletal Proteins - deficiency | Isoenzymes - metabolism | Choline Deficiency - metabolism | Choline Deficiency - genetics | Lipid Metabolism - genetics | NF-E2-Related Factor 2 - genetics | Fatty Acids - metabolism | Kelch-Like ECH-Associated Protein 1 | Disease Models, Animal | Methionine - deficiency | Fatty Liver - genetics | Severity of Illness Index | Fatty Liver - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Fatty Liver - prevention & control | Glutathione Transferase - metabolism | Organ Size | Genotype | Choline Deficiency - pathology | NF-E2-Related Factor 2 - deficiency | Mice, Knockout | Phenotype | Animals | Adaptor Proteins, Signal Transducing - deficiency | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | Lipid Peroxidation | Fatty Liver - etiology | Cysteine | Liver | Glutamate | Fatty acids | Cystine | Antioxidants | Messenger RNA | Fatty liver | Synthesis | Ligases | Glutathione transferase | Choline | Physiological aspects | Fibroblast growth factors | Protein binding | Index Medicus | Animal models | DIGESTIVE SYSTEM | 60 APPLIED LIFE SCIENCES | STRESSES | AMMONIUM COMPOUNDS | ELEMENTS | HYDROXY COMPOUNDS | DIET | GLANDS | AMINO ACIDS | QUATERNARY AMMONIUM COMPOUNDS | DRUGS | ORGANIC SULFUR COMPOUNDS | VERTEBRATES | MICE | RADIOPROTECTIVE SUBSTANCES | METHIONINE | MAMMALS | ANIMALS | RODENTS | ANTIOXIDANTS | RESPONSE MODIFYING FACTORS | CHOLINE | ORGANIC COMPOUNDS | ORGANIC ACIDS | NONMETALS | POLYPEPTIDES | OXYGEN | ALCOHOLS | LIPOTROPIC FACTORS | ORGANS | PEPTIDES | GLUTATHIONE | LIVER | CARBOXYLIC ACIDS | PROTEINS | BODY
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