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Journal Article
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 03/2008, Volume 73, Issue 3, pp. 789 - 800
In addition to being an important receptor in leukocyte activation and mobilization, CCR5 is the essential coreceptor for human immunodeficiency virus (HIV). A... 
AMINO-TERMINAL DOMAIN | PROTEIN | ENTRY | CORECEPTOR | RECEPTOR ANTAGONISTS | IMMUNODEFICIENCY-VIRUS TYPE-1 | ANTI-HIV-1 ACTIVITY | PHARMACOLOGY & PHARMACY | HIGHLY POTENT | INHIBITOR | BINDING | Anti-HIV Agents - pharmacology | Benzoates - metabolism | Humans | Receptors, CCR5 - genetics | Piperazines - chemistry | Pyrimidines - metabolism | Receptors, CCR5 - metabolism | Piperidines - pharmacology | Amides - metabolism | Anti-HIV Agents - metabolism | Radioligand Assay | Binding Sites | Amides - pharmacology | Anti-HIV Agents - classification | Amino Acid Sequence | Piperidines - metabolism | Models, Molecular | Pyrimidines - pharmacology | HIV Fusion Inhibitors - pharmacology | Piperazines - pharmacology | Triazoles - metabolism | Anti-HIV Agents - chemistry | Amides - chemistry | Benzoates - pharmacology | Hydrophobic and Hydrophilic Interactions | Receptors, CCR5 - chemistry | Quaternary Ammonium Compounds - pharmacology | Cricetulus | Triazoles - chemistry | Benzoates - chemistry | Cyclohexanes - pharmacology | Molecular Sequence Data | Piperazines - metabolism | Quaternary Ammonium Compounds - chemistry | Pyrimidines - chemistry | Cyclohexanes - metabolism | Transfection | Inhibitory Concentration 50 | Cyclohexanes - chemistry | Molecular Structure | Membrane Fusion - drug effects | Spiro Compounds - chemistry | CCR5 Receptor Antagonists | CHO Cells | Protein Structure, Tertiary | Cricetinae | Piperidines - chemistry | Mutagenesis, Site-Directed | Protein Structure, Secondary | HIV-1 - drug effects | Static Electricity | Sequence Homology, Amino Acid | Triazoles - pharmacology | Animals | Quaternary Ammonium Compounds - metabolism | Spiro Compounds - pharmacology | Spiro Compounds - metabolism
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2014, Volume 171, Issue 3, pp. 646 - 662
Background and PurposeWhile selective, bitter tasting, TAS2R agonists can relax agonist-contracted airway smooth muscle (ASM), their mechanism of action is... 
TAS2R | 2‐photon microscopy | asthma | mouse lung slice | adrenergic receptor agonists | 2-photon microscopy | CELLS | INTRACELLULAR CALCIUM | RELAXATION | CHLOROQUINE | FORMOTEROL | INOSITOL 1,4,5-TRISPHOSPHATE | CONTRACTION | RYANODINE RECEPTORS | FREQUENCY | PHARMACOLOGY & PHARMACY | CA2+ OSCILLATIONS | Airway Resistance - drug effects | Receptors, G-Protein-Coupled - metabolism | Receptors, G-Protein-Coupled - agonists | Lung - cytology | Chloroquine - pharmacology | Muscle, Smooth - drug effects | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Inositol 1,4,5-Trisphosphate Receptors - agonists | Caffeine - pharmacology | Quinine - pharmacology | Female | Inositol 1,4,5-Trisphosphate - analogs & derivatives | Lung - metabolism | Phosphodiesterase Inhibitors - chemistry | Ryanodine - pharmacology | Phosphodiesterase Inhibitors - pharmacology | Bronchodilator Agents - pharmacology | Drug Resistance - drug effects | Muscle, Smooth - metabolism | Calcium Channel Blockers - pharmacology | Ryanodine - antagonists & inhibitors | Caffeine - antagonists & inhibitors | Animals | Calcium Signaling - drug effects | Lung - drug effects | Calcium Channel Blockers - chemistry | Mice | Mice, Inbred BALB C | Taste | Muscle Relaxation - drug effects | Muscle, Smooth - cytology | In Vitro Techniques | Inositol 1,4,5-Trisphosphate - metabolism | Quaternary Ammonium Compounds - pharmacology | Fluorescence | Smooth muscle | Photolysis | Asthma | Caffeine | Muscular system | Microscopy | Rodents | Research Papers | β2-adrenergic receptor agonists
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 08/2013, Volume 57, Issue 8, pp. 3488 - 3497
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2013, Volume 344, Issue 1, pp. 23 - 32
Journal Article
Journal Article