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Addiction, ISSN 0965-2140, 04/2017, Volume 112, Issue 4, pp. 640 - 648
Journal Article
Journal Article
ChemBioChem, ISSN 1439-4227, 08/2017, Volume 18, Issue 16, pp. 1583 - 1588
We measured the affinity of five molecular container compounds (calabadions 1 and 2, CB[7], sulfocalix[4]arene, and HP‐β‐CD) toward seven drugs of abuse in... 
drugs of abuse | reversal agent | methamphetamine | molecular container | calabadion | BUTYRYLCHOLINESTERASE | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | OVERDOSE | VACCINE | COCAINE | HOST | SOLUBILIZING EXCIPIENTS | NEUROMUSCULAR-BLOCKING-AGENTS | AFFINITY | SYSTEMS | 2-Hydroxypropyl-beta-cyclodextrin - pharmacology | Sequestering Agents - pharmacology | Methamphetamine - toxicity | Imidazoles - chemistry | Crystallography, X-Ray | Male | Methamphetamine - chemistry | Heterocyclic Compounds, 4 or More Rings - pharmacology | Sulfonic Acids - chemistry | Calixarenes - chemistry | Bridged-Ring Compounds - chemistry | Fentanyl - chemistry | Bridged-Ring Compounds - pharmacology | Sequestering Agents - chemistry | Locomotion - drug effects | Phenols - pharmacology | Calixarenes - pharmacology | Heterocyclic Compounds, 4 or More Rings - chemistry | Imidazoles - pharmacology | Sulfonic Acids - pharmacology | Rats, Sprague-Dawley | Animals | 2-Hydroxypropyl-beta-cyclodextrin - chemistry | Phenols - chemistry | Street Drugs - toxicity | Street Drugs - chemistry | Illegal drugs | Containers | Drug abuse | Structure | Crystals | Methamphetamine | Drugs | Rats | Titration calorimetry | In vitro testing | Bioavailability | Heat measurement | pH effects | Optimization | Calorimetry | Titration | Intoxication | Crystal structure | cucurbituril
Journal Article
NATURE, ISSN 0028-0836, 01/2011, Volume 469, Issue 7329, pp. 241 - 244
beta-adrenergic receptors (beta ARs) are G-protein-coupled receptors (GPCRs) that activate intracellular G proteins upon binding catecholamine agonist ligands... 
CRYSTALLIZATION | AMINO-ACID | ACTIVATION | LIGAND-BINDING | BETA-ADRENERGIC-RECEPTORS | PROTEIN-COUPLED RECEPTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CRYSTALLOGRAPHY | HIGH-AFFINITY BINDING | BETA-ADRENERGIC RECEPTOR | Dobutamine - metabolism | Hydroxyquinolines - chemistry | Catecholamines - metabolism | Albuterol - pharmacology | Amphetamines - pharmacology | Adrenergic beta-1 Receptor Antagonists - pharmacology | Crystallography, X-Ray | Adrenergic beta-1 Receptor Agonists - chemistry | Structure-Activity Relationship | Receptors, Adrenergic, beta-1 - chemistry | Adrenergic beta-1 Receptor Agonists - pharmacology | Turkeys | Adrenergic beta-1 Receptor Antagonists - chemistry | Drug Design | Adrenergic beta-1 Receptor Antagonists - metabolism | Dobutamine - chemistry | Isoproterenol - chemistry | Binding Sites | Hydroxyquinolines - pharmacology | Amphetamines - chemistry | Drug Partial Agonism | Albuterol - metabolism | Hydroxyquinolines - metabolism | Isoproterenol - metabolism | Models, Molecular | Receptors, Adrenergic, beta-1 - metabolism | Serine - chemistry | Serine - metabolism | Dobutamine - pharmacology | Animals | Hydrogen Bonding | Amphetamines - metabolism | Isoproterenol - pharmacology | Protein Stability - drug effects | Albuterol - chemistry | Ligands | Protein Conformation | Adrenergic beta-1 Receptor Agonists - metabolism
Journal Article
NATURE, ISSN 0028-0836, 05/2015, Volume 521, Issue 7552, pp. 322 - 322
Na+/Cl--coupled biogenic amine transporters are the primary targets of therapeutic and abused drugs, ranging from antidepressants to the psychostimulants... 
BIOGENIC-AMINE TRANSPORTERS | COCAINE BINDING | SEROTONIN TRANSPORTER | SUBSTRATE TRANSPORT | BACTERIAL HOMOLOG | MULTIDISCIPLINARY SCIENCES | RAT-BRAIN SYNAPTOSOMES | CONFORMATIONAL DYNAMICS | ALTERNATING-ACCESS | TRANSMITTER UPTAKE | MAMMALIAN-CELLS | Dopamine - chemistry | Dopamine Plasma Membrane Transport Proteins - metabolism | Cocaine - metabolism | Molecular Conformation | Crystallography, X-Ray | Dopamine Plasma Membrane Transport Proteins - chemistry | Methamphetamine - chemistry | Sodium - metabolism | Antidepressive Agents - metabolism | Antidepressive Agents - chemistry | Chlorides - metabolism | Central Nervous System Stimulants - metabolism | Dextroamphetamine - chemistry | Protein Stability | Binding Sites | Dopamine - metabolism | Cocaine - chemistry | Dextroamphetamine - metabolism | Neurotransmitter Agents - metabolism | Models, Molecular | Phenethylamines - metabolism | Cocaine - analogs & derivatives | Methamphetamine - metabolism | Neurotransmitter Agents - chemistry | Animals | Dopamine - analogs & derivatives | Drosophila melanogaster - chemistry | Central Nervous System Stimulants - chemistry | Ligands | Physiological aspects | Neurotransmitters | Dopamine | Research | Neurological research | Biological transport | Methamphetamines | Mutagenesis | Antidepressants | Nervous system | Cocaine | Binding sites
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 02/2012, Volume 1248, Issue 1, pp. 18 - 38
Journal Article
Book