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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2006, Volume 103, Issue 39, pp. 14602 - 14607
Allopregnanolone (ALLO) and tetrahydrodeoxycorticosterone (THDOC) are potent positive allosteric modulators of GABA action at receptors. ALLO and THDOC are... 
Brain | Enzymes | Receptors | Messenger RNA | Neurons | Purkinje cells | Pyramidal cells | Neuroglia | Antibodies | Hippocampus | Glutamatergic neurons | 5α-reductase (type I) | GABAergic neurons | 3α-hydroxysteroid dehydrogenase | GABA(A) RECEPTOR FUNCTION | ALLOPREGNANOLONE SYNTHESIS | SOCIAL-ISOLATION | REELIN MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | IN-SITU HYBRIDIZATION | STEROID 5-ALPHA-REDUCTASE | glutamatergic neurons | 3 alpha-hydroxysteroid dehydrogenase | NEUROACTIVE STEROIDS | 5 alpha-reductase (type I) | GAMMA-AMINOBUTYRIC-ACID | RAT-BRAIN | 3-ALPHA-HYDROXYSTEROID DIHYDRODIOL DEHYDROGENASE | Brain - enzymology | Male | Neurons - cytology | Cerebellum - enzymology | RNA, Messenger - metabolism | Cerebral Cortex - cytology | Corpus Striatum - cytology | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - genetics | Amygdala - enzymology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Hippocampus - enzymology | Corpus Striatum - enzymology | Olfactory Bulb - cytology | Olfactory Bulb - enzymology | Cerebral Cortex - enzymology | RNA, Messenger - genetics | Thalamus - enzymology | Rats | Amygdala - cytology | Hippocampus - cytology | Desoxycorticosterone - analogs & derivatives | Desoxycorticosterone - biosynthesis | Gene Expression Regulation, Enzymologic | Membrane Proteins | Animals | Pregnanolone - biosynthesis | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - metabolism | Neurons - enzymology | Cerebellum - cytology | Thalamus - cytology | Mice | GABA | Research | Progesterone | Oxidoreductases | Structure | Steroids | Biological Sciences
Journal Article
Neuron, ISSN 0896-6273, 2002, Volume 34, Issue 5, pp. 807 - 820
Extracellular signal-regulated kinases (ERK1 and 2) are synaptic signaling components necessary for several forms of learning. In mice lacking ERK1, we observe... 
MOLECULAR MECHANISMS | RECEPTOR MUTANT MICE | ACTIVATED PROTEIN-KINASE | SIGNALING PATHWAY | RAS | DOPAMINE | COCAINE | LONG-TERM POTENTIATION | EXPRESSION | NEUROSCIENCES | NUCLEUS-ACCUMBENS | Nerve Net - abnormalities | Synaptic Transmission - genetics | Male | Nerve Net - enzymology | Presynaptic Terminals - ultrastructure | Corpus Striatum - cytology | Nerve Net - cytology | Corpus Striatum - abnormalities | Amygdala - enzymology | Nucleus Accumbens - enzymology | Presynaptic Terminals - enzymology | Nervous System Malformations - enzymology | Mitogen-Activated Protein Kinase 1 - genetics | Nucleus Accumbens - cytology | Behavior, Animal - drug effects | Female | Hippocampus - enzymology | Nervous System Malformations - genetics | Corpus Striatum - enzymology | Cognition Disorders - enzymology | Nucleus Accumbens - abnormalities | Morphine - pharmacology | MAP Kinase Kinase Kinases - genetics | Nervous System Malformations - pathology | Cognition Disorders - pathology | Amygdala - cytology | Behavior, Animal - physiology | Up-Regulation - genetics | Cognition Disorders - genetics | Long-Term Potentiation - genetics | MAP Kinase Kinase Kinases - metabolism | Avoidance Learning - physiology | Hippocampus - cytology | Mutation - genetics | Mice, Knockout | Mitogen-Activated Protein Kinases - deficiency | Motor Activity - genetics | Animals | Mitogen-Activated Protein Kinases - genetics | Mice | Mitogen-Activated Protein Kinase 3 | Memory - physiology | Mitogen-Activated Protein Kinase 1 - metabolism | Proteins | Phosphorylation | Behavior | Kinases | Gene expression | Rodents
Journal Article
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7321, pp. 270 - 276
Journal Article
Epilepsy and Behavior, ISSN 1525-5050, 2015, Volume 51, pp. 96 - 103
Journal Article
Journal Article