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Journal Article
Molecular neurobiology, ISSN 1559-1182, 10/2015, Volume 53, Issue 8, pp. 5710 - 5721
...-β precursor protein (APP) by β-secretases (BACE1), whereas APP cleavage by α-secretases (ADAM10) abrogates Aβ formation. We now mapped the synaptic localization of APP, ADAM10, and BACE1 in the mouse cerebral cortex... 
BACE1 | Neurology | APP | Neurosciences | Biomedicine | Alzheimer’s disease | Neurobiology | ADAM10 | Synapses | Cell Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Amyloid Precursor Protein Secretases - metabolism | Animals | Synapses - metabolism | Mice, Inbred C57BL | Alzheimer Disease - metabolism | Amyloid beta-Protein Precursor - metabolism | Protein Binding | Male | Cerebral Cortex - metabolism | Disease Models, Animal | Index Medicus
Journal Article
International journal of molecular medicine, ISSN 1107-3756, 2014, Volume 34, Issue 1, pp. 160 - 166
Amyloid precursor protein (APP) and beta-site APP cleaving enzyme (BACE-1) play important roles in the pathogenesis of Alzheimer's disease (AD... 
β-site amyloid precursor protein cleaving enzyme | MicroRNA | Alzheimer's disease | Amyloid precursor protein | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Amyloid Precursor Protein Secretases - genetics | RNA, Small Interfering - genetics | MicroRNAs - antagonists & inhibitors | Amyloid beta-Peptides - pharmacology | Humans | Middle Aged | Male | MicroRNAs - metabolism | Peptide Fragments - pharmacology | Aspartic Acid Endopeptidases - genetics | Hippocampus - drug effects | Case-Control Studies | Alzheimer Disease - pathology | Amyloid beta-Peptides - genetics | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Cognitive Dysfunction - genetics | Female | 3' Untranslated Regions | Binding Sites | Peptide Fragments - genetics | Biomarkers - metabolism | Severity of Illness Index | Cell Line | Peptide Fragments - metabolism | Signal Transduction | Gene Expression Regulation | Mice, Transgenic | Cognitive Dysfunction - blood | Hippocampus - pathology | Cognitive Dysfunction - cerebrospinal fluid | Cognitive Dysfunction - pathology | Alzheimer Disease - cerebrospinal fluid | Hippocampus - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Aspartic Acid Endopeptidases - metabolism | Aged | Mice | MicroRNAs - genetics | Alzheimer Disease - genetics | Alzheimer Disease - blood | RNA, Small Interfering - metabolism
Journal Article