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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 14
Neuropathologists assess vast brain areas to identify diverse and subtly-differentiated morphologies. Standard semi-quantitative scoring approaches, however,... 
Concept learning | Brain | Brain architecture | Segmentation | Image processing | Artificial neural networks | Mapping | Anatomy | Image segmentation | Cerebral amyloid angiopathy | Maps | Neural networks | Confidence | Correlation analysis | Morphology | Classification | Phenotyping | Machine learning | Localization | Plaques
Journal Article
Alzheimer's Research & Therapy, ISSN 1758-9193, 12/2019, Volume 11, Issue 1, pp. 1 - 12
Background Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine. Chronic inflammation induced by amyloid β proteins (Aβ) is one... 
Brain | Oxidative stress | Stroke | Cytokines | Pathogenesis | Metabolism | Patients | Inflammatory diseases | Proteins | Signal transduction | Transgenic animals | Rodents | Alzheimers disease | Age | Dementia | Apoptosis | Amyloid | MIF | Alzheimer’s disease | Neuronal toxicity | Microglia | Cognitive impairment
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4600 - 12
Amyloid-beta (A(beta) is the main constituent of amyloid deposits in Alzheimer's disease (AD). The neuropathology is associated with neuroinflammation. Here,... 
DEPOSITS | ALZHEIMERS-DISEASE | AMYLOID-BETA | SULFATE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | LIPOPOLYSACCHARIDE | RECEPTOR | PRECURSOR PROTEIN | APOLIPOPROTEIN-E | Transgenic animals | Rodents | Transgenic mice | Inflammation | Tumor necrosis factor-α | Solubilization | IL-1β | Alzheimer's disease | CD45 antigen | Enzyme-linked immunosorbent assay | Lipopolysaccharides
Journal Article
ACTA NEUROPATHOLOGICA COMMUNICATIONS, ISSN 2051-5960, 02/2019, Volume 7, Issue 1, pp. 26 - 26
Journal Article
Alzheimer's Research & Therapy, ISSN 1758-9193, 12/2019, Volume 11, Issue 1, pp. 56 - 56
Background Intracerebral inoculation of extracts from post-mortem human Alzheimer’s disease brains into mice produces a prion-like spreading effect of... 
Performance evaluation | Proteins | Brain | Pathology | Membranes | Hypotheses | Transgenic animals | Aging | Alzheimers disease | Binding sites | Prion-like hypothesis | Amyloid-β | Alzheimer’s disease | Amyloid-β internalization | Proteomics
Journal Article
Molecular Neurodegeneration, ISSN 1750-1326, 12/2019, Volume 14, Issue 1, pp. 1 - 14
Currently, over five million Americans suffer with Alzheimer’s disease (AD). In the absence of a cure, this number could increase to 13.8 million by 2050. A... 
Neuroimaging | Biomedical research | Disease | Clinical trials | Proteins | Neurodegeneration | Functional magnetic resonance imaging | Aging | Amyloid | Alzheimer's disease | Age | Medical imaging | Cortex | Glycoproteins | Inflammation | Pathology | Brain research | Tau protein | Anisotropy | Neural networks | Epigenetics | Biomarkers | Connectivity | Positron emission tomography | Dementia | Tracers
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 1 - 13
The presence of amyloid beta (A beta) plaques in the brain of some individuals with Creutzfeldt-Jakob or Gertsmann-Straussler-Scheinker diseases suggests that... 
NEUROFIBRILLARY TANGLES | TRANSMISSION | PROTEIN | MULTIDISCIPLINARY SCIENCES | SECRETASE CLEAVAGE | A-BETA | TACE | MICE | CREUTZFELDT-JAKOB-DISEASE | ACCUMULATION | ALZHEIMER-TYPE NEUROPATHOLOGY | Brain | Deregulation | Seeds | Peptides | Trimers | Monomers | Amyloid precursor protein | Accumulation | Infectivity | Prions | Mice | Prion protein | Alzheimer's disease | Deposition | Secretase | Plaques | Index Medicus
Journal Article
Alzheimer's Research & Therapy, ISSN 1758-9193, 12/2019, Volume 11, Issue 1, pp. 1 - 15
The cerebrospinal fluid (CSF) biochemical markers (biomarkers) Amyloidβ 42 (Aβ42), total Tau (T-tau) and Tau phosphorylated at threonine 181 (P-tau181) have... 
Pathology | Accuracy | Working groups | Meetings | Neurodegeneration | Biomarkers | Dementia | Aβ42/40 ratio | Alzheimer’s Disease | Amyloidβ Peptides | Cerebrospinal Fluid
Journal Article