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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 29, pp. 11848 - 11853
Journal Article
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7526, pp. 274 - 278
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2013, Volume 62, pp. 90 - 101
Journal Article
The Journal of Chemical Physics, ISSN 0021-9606, 01/2018, Volume 148, Issue 4, p. 045103
Using a variant of Hamilton-replica-exchange, we study for wild type and Iowa mutant Aβ40 the conversion between fibrils with antiparallel β-sheets and such... 
Models, Molecular | Amyloid beta-Peptides - chemistry | Mutation | Protein Structure, Secondary | Amyloid beta-Peptides - genetics | Humans
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1241 - 1245
Aβ (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory... 
Oligomers | Yeasts | Endocytosis | Receptors | Neurons | Secretion | RESEARCH ARTICLES | Predisposing factors | Cell membranes | Alzheimers disease | Genetic screening | COMMON VARIANTS | CELLS | IDENTIFIES VARIANTS | MEMBRANE | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM | ALPHA-SYNUCLEIN | SACCHAROMYCES-CEREVISIAE | PEPTIDE | OLIGOMERS | GENOME-WIDE ASSOCIATION | Genetic Testing | Saccharomyces cerevisiae - genetics | Humans | Protein Multimerization | Secretory Pathway | Glutamates - metabolism | Saccharomyces cerevisiae - metabolism | Monomeric Clathrin Assembly Proteins - genetics | Amyloid beta-Peptides - genetics | Monomeric Clathrin Assembly Proteins - metabolism | Amyloid beta-Peptides - metabolism | Neurons - physiology | Cell Membrane - metabolism | Peptide Fragments - genetics | Peptide Fragments - metabolism | Caenorhabditis elegans - metabolism | Disease Susceptibility | Genetic Association Studies | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Risk Factors | Cells, Cultured | Rats | Saccharomyces cerevisiae Proteins - genetics | Clathrin - metabolism | Protein Transport | Saccharomyces cerevisiae - cytology | Peptide Fragments - chemistry | Animals | Caenorhabditis elegans - cytology | Alzheimer Disease - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cytoskeleton - metabolism | Amyloid beta-Peptides - chemistry | Alzheimer Disease - genetics | Saccharomyces cerevisiae - growth & development | Index Medicus | Basic Medicine | Other Basic Medicine | peptide | membrane | Medical and Health Sciences | Medicin och hälsovetenskap | oligomers | alpha-synuclein | saccharomyces cerevisiae | cells | identifies variants | Medicinska och farmaceutiska grundvetenskaper | Annan medicinsk grundvetenskap | genome-wide association | endoplasmic reticulum | common variants
Journal Article