X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (32259) 32259
Newsletter (6683) 6683
Newspaper Article (3530) 3530
Magazine Article (208) 208
Book Chapter (118) 118
Dissertation (118) 118
Streaming Video (95) 95
Transcript (67) 67
Book / eBook (38) 38
Publication (32) 32
Web Resource (21) 21
Conference Proceeding (20) 20
Reference (17) 17
Book Review (7) 7
Government Document (1) 1
Journal / eJournal (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
alzheimer's disease (26744) 26744
amyloid beta-protein (21846) 21846
humans (17011) 17011
animals (14185) 14185
neurosciences (12163) 12163
alzheimers-disease (8600) 8600
mice (7556) 7556
research (6833) 6833
amyloid beta-protein precursor - metabolism (6558) 6558
alzheimer disease - metabolism (6475) 6475
male (6262) 6262
amyloid beta-peptides - metabolism (5778) 5778
amyloid beta-protein precursor - genetics (5771) 5771
brain (5697) 5697
amyloid precursor protein (5673) 5673
biochemistry & molecular biology (5411) 5411
female (4998) 4998
alzheimer disease - pathology (4841) 4841
alzheimer disease - genetics (4467) 4467
mice, transgenic (4442) 4442
analysis (4100) 4100
medical research (4011) 4011
disease models, animal (4002) 4002
alzheimers disease (3754) 3754
alzheimer’s disease (3737) 3737
proteins (3573) 3573
medicine, experimental (3529) 3529
aged (3512) 3512
brain - metabolism (3477) 3477
neurology (3314) 3314
a-beta (3252) 3252
rats (3249) 3249
peptides (3232) 3232
dementia (3137) 3137
clinical neurology (3093) 3093
transgenic mice (2804) 2804
physiological aspects (2780) 2780
cell biology (2714) 2714
pathology (2702) 2702
neurons (2679) 2679
neurodegenerative diseases (2648) 2648
brain - pathology (2632) 2632
amyloid (2480) 2480
oxidative stress (2462) 2462
mutation (2410) 2410
middle aged (2346) 2346
neurons - metabolism (2232) 2232
mice, inbred c57bl (2127) 2127
cells, cultured (2113) 2113
alzheimer disease - physiopathology (2081) 2081
mouse model (2055) 2055
neurodegeneration (2049) 2049
peptide (2040) 2040
aged, 80 and over (2017) 2017
universities and colleges (1990) 1990
alzheimer disease - drug therapy (1954) 1954
precursor protein (1944) 1944
expression (1936) 1936
immunohistochemistry (1870) 1870
peptide fragments - metabolism (1824) 1824
protein (1813) 1813
amyloid-beta (1806) 1806
alzheimer disease (1805) 1805
multidisciplinary sciences (1775) 1775
in-vivo (1758) 1758
disease (1754) 1754
genetic aspects (1747) 1747
memory (1737) 1737
phosphorylation (1697) 1697
molecular sequence data (1685) 1685
beta-protein (1673) 1673
risk factors (1673) 1673
health aspects (1668) 1668
β-amyloid (1637) 1637
development and progression (1629) 1629
amino acid sequence (1584) 1584
apoptosis (1574) 1574
pharmacology & pharmacy (1520) 1520
oligomers (1507) 1507
mental disorders (1505) 1505
amyloid-beta-protein (1495) 1495
presenilin-1 - genetics (1449) 1449
rodents (1444) 1444
aging (1434) 1434
cells (1432) 1432
research article (1424) 1424
geriatrics & gerontology (1422) 1422
protein binding (1417) 1417
amyloid precursor protein secretases - metabolism (1411) 1411
enzymes (1409) 1409
app (1373) 1373
drug therapy (1367) 1367
mild cognitive impairment (1364) 1364
inflammation (1343) 1343
hippocampus (1338) 1338
biochemistry (1337) 1337
hippocampus - metabolism (1331) 1331
tau proteins - metabolism (1325) 1325
cell line (1316) 1316
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (22) 22
Gerstein Science - Stacks (18) 18
Collection Dvlpm't (Acquisitions) - Vendor file (5) 5
UofT at Mississauga - Stacks (3) 3
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
UofT at Scarborough - Stacks (2) 2
Chemistry (A D Allen) - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (42670) 42670
Japanese (306) 306
Chinese (227) 227
French (86) 86
Spanish (40) 40
Russian (31) 31
German (30) 30
Polish (13) 13
Dutch (11) 11
Hungarian (7) 7
Czech (6) 6
Swedish (6) 6
Norwegian (5) 5
Danish (4) 4
Korean (4) 4
Finnish (3) 3
Portuguese (3) 3
Hebrew (2) 2
Italian (2) 2
Serbian (1) 1
Slovak (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature neuroscience, ISSN 1546-1726, 2004, Volume 8, Issue 1, pp. 79 - 84
.... Here we provide the first direct experimental evidence that a defined molecular species of the amyloid-beta protein interferes with cognitive function... 
Cricetinae | Cricetulus | Amyloid beta-Peptides - pharmacology | Cognition Disorders - chemically induced | Humans | Injections, Intraventricular | Rats | Culture Media, Conditioned - pharmacology | Male | Rats, Sprague-Dawley | Animals | Conditioning, Operant - drug effects | Female | Amyloid beta-Peptides - chemistry | CHO Cells
Journal Article
Nature Chemistry, ISSN 1755-4330, 07/2009, Volume 1, Issue 4, pp. 326 - 331
... structure of each of the aggregates. We applied these methods to a number of the amyloid-beta protein isoforms of A beta 40 and A beta 42 and showed that their oligomer-size distributions are very different. Our results are consistent with previous observations that A beta 40 and A beta 42 self-assemble via different pathways and provide a candidate in the A beta 42 dodecamer for the primary toxic species in Alzheimer's disease. 
A-BETA-42 | FIBRILS | MASS-SPECTROMETER | ASSEMBLIES | NUCLEATION | MONOMER STRUCTURE | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | ONSET | FIBRILLIZATION | Parkinson Disease - pathology | Peptide Fragments - metabolism | Plaque, Amyloid - pathology | Humans | Diabetes Mellitus, Type 2 - metabolism | Protein Isoforms - toxicity | Alzheimer Disease - pathology | Peptide Fragments - chemistry | Protein Isoforms - metabolism | Protein Isoforms - chemistry | Mass Spectrometry | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Plaque, Amyloid - metabolism | Parkinson Disease - metabolism | Amyloid beta-Peptides - chemistry | Diabetes Mellitus, Type 2 - pathology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2016, Volume 36, Issue 35, pp. 9041 - 9056
Journal Article
2006, Advances in protein chemistry, ISBN 0120342731, Volume 73., vii, 320 p., [28] p of plates
Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial... 
Proteins | Amyloid | Prions | Amyloid beta-protein
Book
Journal Article