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BMC pharmacology & toxicology, ISSN 2050-6511, 2014, Volume 15, Issue 1, pp. 23 - 23
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, pp. e100575 - e100575
Background/Objective: Clinical evidence indicates that cerebral ischemia (CI) and a pathological factor of Alzheimer's disease, the beta-amyloid (A beta)... 
IMAGING TECHNIQUES | POSITRON-EMISSION-TOMOGRAPHY | VASCULAR DEMENTIA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | A-BETA | PRECURSOR PROTEIN | MILD COGNITIVE IMPAIRMENT | BLOOD-FLOW | PERFUSION CT | TRANSGENIC MICE | Brain - diagnostic imaging | Rats, Wistar | Brain - physiopathology | Blood Volume - drug effects | Microvessels - drug effects | Microvessels - pathology | Rats | Male | Tomography, X-Ray Computed | Amyloidogenic Proteins - toxicity | Brain Ischemia - physiopathology | Brain - drug effects | Brain - blood supply | Administration, Intravenous | Animals | Contrast Media - administration & dosage | Microvessels - diagnostic imaging | Brain Mapping | Hemodynamics - drug effects | Brain Ischemia - diagnostic imaging | Disease Models, Animal | Neuroimaging | Brain | Neurosciences | Nuclear magnetic resonance--NMR | Peptides | Laboratories | Toxicity | Cognitive ability | Blood | Image acquisition | Proteins | Histopathology | Ischemia | Computed tomography | Blood volume | Transgenic animals | Cerebral blood flow | Rodents | Surgery | Neostriatum | Alzheimer's disease | Image contrast | Stroke | Medical imaging | Neurodegenerative diseases | Hypervolemia | Brain mapping | Biophysics | Blood flow | Brain research | Perfusion | β-Amyloid | Microvasculature | Hemodynamics | Alzheimers disease | CTP | Dementia | Animal cognition | Index Medicus | Nuclear magnetic resonance | NMR | Computer aided tomography
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2016, Volume 6, Issue 1, pp. 23836 - 23836
Journal Article
eLife, ISSN 2050-084X, 05/2016, Volume 5
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2017, Volume 58, Issue 2, pp. 559 - 574
There is an urgent unmet need for new therapeutics for Alzheimer's disease (AD), the most common cause of dementia in the elderly. Therapeutic approaches... 
NMDA | amyloid | neurotoxicity | hippocampus | Alzheimer's disease | neuroprotection | PROTEIN | PROTECTION | NEURONAL CELL-DEATH | SYNAPTIC PLASTICITY | NEUROSCIENCES | IN-VITRO | INHIBITION | TREATMENT STRATEGIES | FAMILIAL ALZHEIMERS-DISEASE | CYTOTOXICITY | BRAIN | Neuroprotective Agents - therapeutic use | Locomotion - genetics | Humans | Motor Activity - drug effects | Male | Excitatory Postsynaptic Potentials - drug effects | Alzheimer Disease - pathology | Brain - metabolism | Pyrones - chemistry | Excitatory Postsynaptic Potentials - genetics | Neuroblastoma - pathology | Disease Models, Animal | Locomotion - drug effects | Alzheimer Disease - physiopathology | Neuroprotective Agents - chemistry | Mice, Inbred C57BL | Alzheimer Disease - drug therapy | Presenilin-1 - genetics | Mice, Transgenic | Amyloidogenic Proteins - toxicity | Mutation - genetics | Brain - drug effects | Motor Activity - genetics | Amyloidogenic Proteins - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Brain - pathology | Cell Line, Tumor | Pyrones - therapeutic use | Drinking Behavior - drug effects | Mice | Pyrones - chemical synthesis | Potentiation | Elderly people | Neuroprotection | Brain | Oxidative stress | Animal models | Toxicity | Glutamic acid receptors (ionotropic) | Memory | Glutamic acid receptors | Drug development | ABCA1 protein | Learning | Rodents | Dementia disorders | Coenzyme A | Amyloid | Neurodegenerative diseases | Long-term potentiation | N-Methyl-D-aspartic acid receptors | Pharmacology | Plasticity (hippocampal) | Acyltransferase | Cholesterol | Properties (attributes) | Excitatory postsynaptic potentials | ATP-binding protein | Elderly | Hippocampus | Sterol O-acyltransferase | Geriatrics | Index Medicus
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