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Science (American Association for the Advancement of Science), ISSN 0036-8075, 03/2012, Volume 335, Issue 6075, pp. 1503 - 1506
Journal Article
Molecular neurobiology, ISSN 1559-1182, 10/2016, Volume 54, Issue 8, pp. 6507 - 6522
Alzheimer’s disease (AD) is associated with reduced insulin level and impairment of insulin receptor (IR) signaling in the brain, which correlates to amyloid... 
Neurology | post synaptic neurotoxicity | Neurosciences | Glial activation | Biomedicine | Neurobiology | Insulin receptor dysfunction | Amyloidogenic protein expression | Intranasal insulin | Cell Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Microglia - metabolism | Streptozocin | Memory Disorders - metabolism | Male | NF-kappa B - metabolism | Hippocampus - drug effects | Insulin Receptor Substrate Proteins - metabolism | Cerebral Cortex - metabolism | Inflammation - metabolism | Hypoglycemic Agents - administration & dosage | Inflammation - drug therapy | Amyloid beta-Peptides - metabolism | Cerebral Cortex - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Hypoglycemic Agents - therapeutic use | Astrocytes - drug effects | Peptide Fragments - metabolism | Cytokines - metabolism | Microglia - drug effects | Rats | Insulin - administration & dosage | Down-Regulation - drug effects | Glycogen Synthase Kinase 3 - metabolism | Administration, Intranasal | Glycogen Synthase Kinase 3 beta - metabolism | Hippocampus - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | Memory Disorders - drug therapy | Spatial Memory - drug effects | Signal Transduction - drug effects | Aspartic Acid Endopeptidases - metabolism | Receptor, Insulin - metabolism | Insulin - therapeutic use | Astrocytes - metabolism | Proteins | Medical research | Memory | Medicine, Experimental | Amyloidosis | Alzheimer's disease | Insulin | Amyloidogenesis | Neuroprotection | Brain | Cerebral cortex | Mental disorders | Impairment | Neuronal-glial interactions | Inflammatory diseases | Neurotoxicity | Cell activation | Rodents | Amyloid | Drug therapy | Translocation | b-Site APP cleaving enzyme 1 | Neurodegenerative diseases | Neurons | Glial fibrillary acidic protein | Caspase | Inflammation | Hypoglycemia | Pathology | Tumor necrosis factor | Interleukin 10 | Cyclooxygenase-2 | b-Site APP cleaving enzyme | Alzheimers disease | Index Medicus
Journal Article
Neurobiology of aging, ISSN 0197-4580, 01/2017, Volume 49, pp. 60 - 68
Journal Article
PloS one, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e94287 - e94287
The development of an effective therapy for Alzheimer's disease (AD) is a major challenge to biomedical sciences. Because much of early AD pathophysiology... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Alzheimer Disease - complications | Growth Differentiation Factor 2 - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Gliosis - physiopathology | Nerve Growth Factors - metabolism | Glial Fibrillary Acidic Protein - metabolism | Neurogenesis | Choline O-Acetyltransferase - metabolism | Alzheimer Disease - pathology | Gliosis - pathology | Amyloid beta-Peptides - metabolism | Hippocampus - enzymology | Amyloidosis - complications | Disease Models, Animal | Biomarkers - metabolism | Alzheimer Disease - physiopathology | Amyloidosis - pathology | Plaque, Amyloid - pathology | Cholinergic Neurons - metabolism | Activin Receptors, Type I - metabolism | Amyloidosis - physiopathology | Mice, Transgenic | Neuropeptides - metabolism | Hippocampus - pathology | Gliosis - complications | Insulin-Like Growth Factor II - metabolism | Plaque, Amyloid - complications | Hippocampus - metabolism | Animals | Activin Receptors, Type II | Plaque, Amyloid - physiopathology | Insulin-Like Growth Factor II - administration & dosage | Alzheimer Disease - metabolism | Mice | Cholinergic Neurons - pathology | Care and treatment | Physiological aspects | Fluorescence | Nerve growth factor | Acetylcholine | Amyloidosis | Diagnosis | Health aspects | Risk factors | Brain | Neuropathology | Insulin-like growth factor I | Memory | Insulin-like growth factors | Choline O-acetyltransferase | Neurotrophin 3 | Proteins | Infusion | Consolidation | Transgenic animals | Rodents | Doublecortin protein | Amyloid | Acetyltransferase | Insulin-like growth factor II | Trophic factors | Alzheimer's disease | Plaques | Neurodegenerative diseases | Neurons | Abnormalities | Gene expression | Insulin | Medicine | Pathology | Brain-derived neurotrophic factor | Presenilin 1 | Choline | Green fluorescent protein | Mutation | Laboratory animals | Bone morphogenetic protein 9 | Hippocampus | Index Medicus
Journal Article
Molecular neurobiology, ISSN 0893-7648, 12/2016, Volume 53, Issue 10, pp. 6730 - 6744
Our earlier studies showed that insulin receptor (IR) dysfunction along with neuroinflammation and amyloidogenesis played a major role in streptozotocin... 
Neurology | Neurotrophic factor | Neurosciences | Biomedicine | Memantine | Insulin receptor signaling | Astrocytes | Neurobiology | Amyloidogenic protein expression | Streptozotocin | Cell Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Inflammation - pathology | Streptozocin | Astrocytes - pathology | Nitrites - metabolism | NF-kappa B - metabolism | Nerve Growth Factors - metabolism | Insulin Receptor Substrate Proteins - metabolism | RNA, Messenger - metabolism | Inflammation - metabolism | Amyloid - metabolism | Nervous System - pathology | Amyloid beta-Protein Precursor - metabolism | Phosphorylation - drug effects | Biomarkers - metabolism | Astrocytes - drug effects | Insulysin - metabolism | Memantine - pharmacology | RNA, Messenger - genetics | Rats | Down-Regulation - drug effects | Glycogen Synthase Kinase 3 - metabolism | Glycogen Synthase Kinase 3 beta - metabolism | Animals | Signal Transduction - drug effects | Nerve Growth Factors - genetics | Cyclooxygenase 2 - metabolism | Fluorescent Antibody Technique | Cell Line, Tumor | Receptor, Insulin - metabolism | Oxidative Stress - drug effects | Astrocytes - metabolism | Nitric Oxide Synthase Type II - metabolism | COX-2 inhibitors | Methyl aspartate | Amyloid beta-protein | Amyloidosis | Intermediate filament proteins | Nervous system agents | Alzheimer's disease | Insulin | Studies | Proteins | Index Medicus
Journal Article
Brain Research Bulletin, ISSN 0361-9230, 2017, Volume 131, pp. 133 - 141
Highlights • MJ reversed LPS-induced memory deficits in mice. • The increased brain levels of PGE2, TNFα and IL1β in LPS-treated mice were reduced by MJ. • MJ... 
Neurology | Lipopolysaccharide | Memory impairment | Pro-inflammatory mediators | Methyl jasmonate | Beta-amyloid | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Inflammation - chemically induced | Memory - drug effects | Tumor Necrosis Factor-alpha - metabolism | Neuroimmunomodulation - immunology | Lipopolysaccharides - metabolism | Male | NF-kappa B - metabolism | Neuroimmunomodulation - physiology | Oxylipins - therapeutic use | Lipopolysaccharides - adverse effects | Brain - metabolism | Interleukin-1beta - metabolism | Amyloid beta-Peptides - metabolism | Acetates - therapeutic use | Biomarkers - metabolism | Astrocytes - drug effects | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Acetates - metabolism | Cyclopentanes - pharmacology | Maze Learning - drug effects | Oxylipins - metabolism | Animals | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Memory Disorders - therapy | Oxylipins - pharmacology | Prefrontal Cortex - metabolism | Cyclopentanes - metabolism | Cyclopentanes - therapeutic use | Acetates - pharmacology | Mice | Prefrontal Cortex - physiology | Memory Disorders - chemically induced | Nitric Oxide Synthase Type II - metabolism | Medical colleges | Mitogens | Memory | Immunohistochemistry | COX-2 inhibitors | Nervous system diseases | Nitric oxide | Prostaglandins E | Amyloidosis | Biological markers | Alzheimer's disease | Index Medicus
Journal Article