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by Jansen, W.J and Ossenkoppele, R and Knol, D.L and Tijms, B.M and Scheltens, P.J and Verhey, F.R.J and Visser, P.J and Aalten, P and Aarsland, D and Alcolea, D and Alexander, M and Almdahl, I.S and Arnold, S.E and Baldeiras, I and Barthel, H and Berckel, B.N. van and Bibeau, K and Blennow, K and Brooks, D.J and Buchem, M.A. van and Camus, V and Cavedo, E and Chen, K and Chetelat, G and Cohen, A.D and ezga, A and Engelborghs, S and Fagan, A.M and Fladby, T and Fleisher, A.S and Flier, W.M. van der and Ford, L and Forster, S and Fortea, J and Foskett, N and Frederiksen, K.S and Freund-Levi, Y and Frisoni, G.B and Froelich, L and Gabryelewicz, T and Gill, K.D and Gkatzima, O and Gomez-Tortosa, E and Gordon, M.F and Grimmer, T and Hampel, H and Hausner, L and Hellwig, S and Herukka, S.K and Hildebrandt, H and Ishihara, L and Ivanoiu, A and Jagust, W.J and Johannsen, P and Kandimalla, R and Kapaki, E and Klimkowicz-Mrowiec, A and Klunk, W.E and Kohler, S and Koglin, N and Kornhuber, J and Kramberger, M.G and Laere, K. Van and Landau, S.M and Lee, D.Y and Leon, M and Lisetti, V and Lleo, A and Madsen, K and Maier, W and Marcusson, J and Mattsson, N and Mendonca, A. de and Meulenbroek, O.V and Meyer, P.T and Mintun, M.A and Mok, V and Molinuevo, J.L and Mollergard, H.M and Morris, J.C and Mroczko, B and Mussele, S. Van der and Na, D.L and Newberg, A and Nordberg, A and Nordlund, A and Novak, G.P and Paraskevas, G.P and Parnetti, L and Perera, G and Peters, O and Popp, J and Prabhakar, S and Rabinovici, G.D and Ramakers, I.H and Rami, L and Oliveira, C.R and Rinne, J.O and Roigue, K.M and Roiguez-Roiguez, E and ... and Amyloid Biomarker Study Grp and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Jama : Journal of the American Medical Association, ISSN 0098-7484, 2015, Volume 313, Issue 19, pp. 1924 - 1938
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2013, Volume 33, Issue 15, pp. 6245 - 6256
Alzheimer's disease (AD) is hallmarked by amyloid plaques, neurofibrillary tangles, and widespread cortical neuronal loss (Selkoe, 2001). The "amyloid cascade... 
NEUROFIBRILLARY TANGLES | MEMORY DEFICITS | DISEASE | AMYLOID-PRECURSOR-PROTEIN | COGNITIVE IMPAIRMENT | MICE | GENE-TRANSFER | SYNAPTIC PLASTICITY | NEUROSCIENCES | MOUSE MODELS | SENILE PLAQUES | Translation | Animal models | Neurodegenerative diseases | Transgenic mice | Cortex | Cognitive ability | Nervous system | beta -Amyloid | Amyloid precursor protein | Neurotoxicity | Neurofibrillary tangles | Gliosis | Tau protein | Presenilin 1 | Dementia disorders | Amyloidosis | Amyloid | Alzheimer's disease | Age | Hippocampus | Plaques | Apoptosis | Alzheimer Disease - complications | Age Factors | Humans | Rats, Inbred F344 | Cerebral Cortex - pathology | Nerve Degeneration - genetics | Tauopathies - pathology | tau Proteins - metabolism | Cognition Disorders - metabolism | Male | Cerebral Cortex - metabolism | Nerve Degeneration - metabolism | Alzheimer Disease - pathology | Behavior, Animal | Gliosis - pathology | Amyloid beta-Peptides - metabolism | Female | Disease Models, Animal | Gliosis - genetics | Plaque, Amyloid - pathology | Rats, Transgenic | Cognition Disorders - pathology | Presenilin-1 - genetics | Rats | Cognition Disorders - genetics | Hippocampus - pathology | Nerve Degeneration - pathology | Plaque, Amyloid - genetics | Hippocampus - metabolism | Cognition Disorders - complications | Tauopathies - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Alzheimer Disease - metabolism | Cerebral Amyloid Angiopathy | Alzheimer Disease - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/1999, Volume 400, Issue 6740, pp. 173 - 177
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 29, pp. 10732 - 10737
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 5/2014, Volume 127, Issue 5, pp. 645 - 665
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 12/2012, Volume 18, Issue 12, pp. 1812 - 1812
The pathology of Alzheimer's disease has an inflammatory component that is characterized by upregulation of proinflammatory cytokines, particularly in response... 
MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | CROHNS-DISEASE | IFN-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CEREBROSPINAL-FLUID | IL-12 RECEPTOR | CELL BIOLOGY | MULTIPLE-SCLEROSIS | PLAQUE PSORIASIS | MOUSE MODEL | DOUBLE-BLIND | T-CELLS | Disease | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Interleukin-12 | Injections, Intraperitoneal | Antibodies | Mice, Transgenic | Cognition | Alzheimer Disease | DNA Primers | Blotting, Western | Microglia | Signaling | Pathology | Animals | Flow Cytometry | Cognition & reasoning | Analysis of Variance | Amyloid beta-Peptides | Mice | Alzheimers disease | Real-Time Polymerase Chain Reaction | Interleukin-12 Subunit p40 | Brain | Animal models | Neurodegenerative diseases | Cognitive ability | Interleukin 12 | Interleukin 23 | beta -Amyloid | Inflammation | Cerebrospinal fluid | Inflammatory diseases | Signal transduction | Amyloidosis | Amyloid | Alzheimer's disease | Interleukin-12 Subunit p40 - genetics | Interleukin-12 Subunit p40 - metabolism | Microglia - metabolism | Interleukin-12 Subunit p40 - cerebrospinal fluid | Interleukin-12 - genetics | DNA Primers - genetics | Interleukin-12 - metabolism | Cognition - drug effects | Alzheimer Disease - pathology | Antibodies - pharmacology | Antibodies - administration & dosage | Signal Transduction - drug effects | Amyloid beta-Peptides - metabolism | Interleukin-12 - immunology | Interleukin-12 Subunit p40 - immunology | Complications and side effects | Care and treatment | Interleukins | Genetic aspects | Research | Memory, Disorders of | Health aspects | Risk factors | Index Medicus
Journal Article
JAMA, ISSN 0098-7484, 06/2017, Volume 317, Issue 22, pp. 2285 - 2287
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2012, Volume 33, Issue 12, pp. 2903 - 2919
Abstract The accumulation of β-amyloid (Aβ) peptide derived from abnormal processing of amyloid precursor protein (APP) is a common pathological hallmark of... 
Neurology | Internal Medicine | Tau phosphorylation | Berberine | TgCRND8 mice | Alzheimer's disease | Amyloid precursor protein | Glycogen synthase kinase | β-amyloid | CYTOPLASMIC DOMAIN | WATER-MAZE | PHOSPHATIDYLINOSITOL 3-KINASE | GLYCOGEN-SYNTHASE KINASE-3 | NEUROSCIENCES | CEREBRAL AMYLOIDOSIS | GERIATRICS & GERONTOLOGY | beta-amyloid | A-BETA | SPATIAL MEMORY | LONG-TERM POTENTIATION | PRECURSOR PROTEIN | N2A CELLS | AKT protein | Coptis | Memory - drug effects | Alzheimer Disease - complications | Humans | Glial Fibrillary Acidic Protein - metabolism | Brain - metabolism | Gliosis - pathology | Transfection | Cognition Disorders - etiology | Amyloid beta-Peptides - metabolism | Membrane Proteins - metabolism | Chromones - pharmacology | Gliosis - etiology | Disease Models, Animal | Peptide Fragments - metabolism | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Cognition Disorders - pathology | Enzyme Inhibitors - pharmacology | ADAM10 Protein | Alzheimer Disease - drug therapy | Morpholines - pharmacology | Mice, Transgenic | Cognition Disorders - drug therapy | Glycogen Synthase Kinase 3 - metabolism | Maze Learning - drug effects | Mutation - genetics | Brain - drug effects | Gene Expression Regulation - drug effects | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Analysis of Variance | Aspartic Acid Endopeptidases - metabolism | Brain - pathology | Cell Line, Tumor | Gliosis - drug therapy | Mice | Berberine - therapeutic use | Alzheimer Disease - genetics | Index Medicus
Journal Article