X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (14807) 14807
Newspaper Article (479) 479
Newsletter (201) 201
Book Chapter (66) 66
Dissertation (25) 25
Publication (16) 16
Magazine Article (13) 13
Book / eBook (12) 12
Transcript (9) 9
Trade Publication Article (6) 6
Government Document (3) 3
Book Review (2) 2
Conference Proceeding (2) 2
Streaming Video (2) 2
Web Resource (2) 2
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (10100) 10100
amyotrophic lateral sclerosis (8311) 8311
amyotrophic-lateral-sclerosis (7813) 7813
animals (7769) 7769
neurosciences (6341) 6341
mice (3885) 3885
male (3780) 3780
amyotrophic lateral sclerosis - metabolism (3286) 3286
female (3278) 3278
amyotrophic lateral sclerosis - genetics (2818) 2818
clinical neurology (2791) 2791
biochemistry & molecular biology (2726) 2726
amyotrophic lateral sclerosis - pathology (2528) 2528
als (2433) 2433
mutation (2387) 2387
middle aged (2343) 2343
neurodegeneration (2299) 2299
proteins (2271) 2271
disease models, animal (2164) 2164
neurons (2163) 2163
aged (2046) 2046
superoxide dismutase - genetics (1988) 1988
disease (1961) 1961
nervous system diseases (1886) 1886
mice, transgenic (1846) 1846
alzheimers-disease (1806) 1806
oxidative stress (1753) 1753
neurology (1735) 1735
neurodegenerative diseases (1701) 1701
cell biology (1684) 1684
analysis (1652) 1652
adult (1544) 1544
motor neurons - metabolism (1485) 1485
research (1470) 1470
superoxide dismutase - metabolism (1464) 1464
frontotemporal lobar degeneration (1460) 1460
pathology (1423) 1423
rats (1329) 1329
brain (1323) 1323
superoxide dismutase-1 (1323) 1323
nervous system (1313) 1313
alzheimer's disease (1297) 1297
mouse model (1283) 1283
physiological aspects (1243) 1243
degeneration (1167) 1167
spinal cord - metabolism (1165) 1165
motor neurons - pathology (1140) 1140
amyotrophic lateral sclerosis - physiopathology (1134) 1134
neurons - metabolism (1128) 1128
genetic aspects (1086) 1086
apoptosis (1073) 1073
dna-binding proteins - metabolism (1066) 1066
immunohistochemistry (1055) 1055
brain - metabolism (1023) 1023
spinal-cord (1013) 1013
spinal cord (1009) 1009
mutations (997) 997
expression (996) 996
spinal cord - pathology (996) 996
multidisciplinary sciences (984) 984
transgenic mice (984) 984
dementia (980) 980
gene expression (976) 976
tdp-43 (971) 971
motor-neuron disease (968) 968
cells, cultured (966) 966
parkinsons-disease (927) 927
metabolism (923) 923
motor neurons (912) 912
superoxide dismutase (880) 880
disease progression (878) 878
rodents (872) 872
frontotemporal dementia (870) 870
protein binding (860) 860
neurodegenerative diseases - metabolism (838) 838
parkinson's disease (825) 825
motor-neurons (824) 824
mice, inbred c57bl (823) 823
medicine (797) 797
pharmacology & pharmacy (784) 784
mitochondria (773) 773
research article (773) 773
aged, 80 and over (746) 746
brain - pathology (740) 740
protein (713) 713
central-nervous-system (711) 711
neuroscience (709) 709
superoxide-dismutase (700) 700
review (697) 697
development and progression (693) 693
dna-binding proteins - genetics (691) 691
amyotrophic lateral sclerosis - enzymology (682) 682
health aspects (678) 678
transgenic mouse model (677) 677
gene (673) 673
phosphorylation (663) 663
biology (650) 650
genetics & heredity (647) 647
motor neuron disease (647) 647
amyotrophic lateral sclerosis - drug therapy (642) 642
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (15476) 15476
Japanese (156) 156
French (33) 33
Russian (33) 33
German (27) 27
Spanish (18) 18
Chinese (13) 13
Polish (12) 12
Portuguese (12) 12
Italian (6) 6
Dutch (4) 4
Hungarian (3) 3
Danish (2) 2
Norwegian (2) 2
Swedish (2) 2
Bosnian (1) 1
Czech (1) 1
Finnish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal of lipid research, ISSN 1539-7262, 2017, Volume 58, Issue 1, pp. 267 - 278
As neurons die, cholesterol is released in the central nervous system (CNS); hence, this sterol and its metabolites may represent a biomarker of neurodegeneration, including in amyotrophic lateral sclerosis (ALS... 
Cytochrome p450 | Brain lipids | Cholestenoic acids | Nuclear receptors/lxr | Oxysterols | Mass spectrometry | Neurodeneneration | Bile acids and salts/biosynthesis | cholestenoic acids | brain lipids | HOMEOSTASIS | bile acids and salts/biosynthesis | LIVER-X RECEPTORS | oxysterols | nuclear receptors/LXR | BIOCHEMISTRY & MOLECULAR BIOLOGY | cytochrome P450 | CEREBROSPINAL-FLUID | BLOOD-BRAIN-BARRIER | MASS-SPECTROMETRY | neurodeneneration | PLASMA | CELL-MIGRATION | NEURONS | 27-HYDROXYCHOLESTEROL | mass spectrometry | Neurons - pathology | Bile Acids and Salts - blood | Central Nervous System - metabolism | Cholesterol - blood | Cholesterol - isolation & purification | Humans | Middle Aged | Central Nervous System - pathology | Male | Amyotrophic Lateral Sclerosis - blood | Bile Acids and Salts - cerebrospinal fluid | Nerve Degeneration - pathology | Nerve Degeneration - cerebrospinal fluid | Lipids - isolation & purification | Amyotrophic Lateral Sclerosis - pathology | Lipids - cerebrospinal fluid | Nerve Degeneration - blood | Amyotrophic Lateral Sclerosis - cerebrospinal fluid | Bile Acids and Salts - isolation & purification | Lipids - blood | Female | Aged | Neurons - metabolism | Cholesterol - cerebrospinal fluid | Neuroprotection | Acids | Metabolites | Sterols | Neurodegeneration | Central nervous system | Amyotrophic lateral sclerosis | Lipid metabolism | Cerebrospinal fluid | Cholesterol | Bile | Index Medicus | nuclear receptors | Patient-Oriented and Epidemiological Research | LXR | biosynthesis | bile acids and salts
Journal Article
Annals of neurology, ISSN 0364-5134, 2013, Volume 74, Issue 1, pp. 20 - 38
Journal Article
Nature neuroscience, ISSN 1546-1726, 2012, Volume 15, Issue 11, pp. 1488 - 1497
FUS/TLS (fused in sarcoma/translocated in liposarcoma) and TDP-43 are integrally involved in amyotrophic lateral sclerosis (ALS... 
NEURODEGENERATIVE DISEASE | GENE | AMYOTROPHIC-LATERAL-SCLEROSIS | FAMILY PROTEINS | FUS PATHOLOGY | MUTATIONS | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING | NEUROSCIENCES | BRAIN | NASCENT TRANSCRIPTION | RNA, Small Interfering - genetics | Protein Binding - genetics | Oligonucleotide Array Sequence Analysis | Humans | tau Proteins - metabolism | Gene Expression Profiling | RNA, Messenger - metabolism | Kv Channel-Interacting Proteins - metabolism | Brain - metabolism | Frontotemporal Dementia - metabolism | RNA Splicing - genetics | Frontotemporal Dementia - genetics | RNA-Binding Protein FUS - deficiency | Amyotrophic Lateral Sclerosis - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | RNA-Binding Protein FUS - genetics | Mice, Knockout | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Shal Potassium Channels - metabolism | Brain - pathology | Mice | Neurofilament Proteins - metabolism | RNA, Small Interfering - metabolism | Immunoprecipitation | Spinal Cord - metabolism | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | tau Proteins - genetics | Cell Cycle Proteins - genetics | Female | RNA Precursors - metabolism | Excitatory Amino Acid Transporter 2 - genetics | Membrane Proteins - metabolism | Frontotemporal Dementia - pathology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | RNA Precursors - genetics | Protein Structure, Tertiary - genetics | RNA-Binding Protein FUS - metabolism | DNA-Binding Proteins - genetics | Excitatory Amino Acid Transporter 2 - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Neural Cell Adhesion Molecules - metabolism | Neural Stem Cells - metabolism | Cell Line, Transformed | Amyotrophic lateral sclerosis | Development and progression | Genetic aspects | Messenger RNA | Health aspects
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 487, Issue 7408, pp. 443 - 448
Journal Article
Brain (London, England : 1878), ISSN 1460-2156, 2011, Volume 134, Issue 5, pp. 1293 - 1314
Amyotrophic lateral sclerosis is a relentless and devastating adult-onset neurodegenerative disease with no known cure... 
IL-4 | FoxP3 | regulatory T lymphocytes | inflammation | microglia | MOTOR-NEURONS | WILD-TYPE MICROGLIA | SPINAL-CORD | ANTIINFLAMMATORY CYTOKINE | NEUROSCIENCES | CLINICAL NEUROLOGY | INHERITED ALS | IMMUNE-SYSTEM | MOUSE MODEL | ANIMAL-MODEL | ALTERNATIVE ACTIVATION | PARKINSONS-DISEASE | T-Lymphocytes, Regulatory - metabolism | Superoxide Dismutase - genetics | Toll-Like Receptor 2 - genetics | Age Factors | Amyotrophic Lateral Sclerosis - physiopathology | Humans | Middle Aged | Male | RNA, Messenger - metabolism | DNA-Binding Proteins - deficiency | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Lectins - metabolism | Flow Cytometry | Forkhead Transcription Factors - metabolism | Spinal Cord - pathology | Adult | Female | beta-N-Acetylhexosaminidases - genetics | Receptors, Chemokine - genetics | Cytokines - genetics | Disease Models, Animal | Cytokines - metabolism | Gene Expression Regulation - genetics | beta-N-Acetylhexosaminidases - metabolism | Amyotrophic Lateral Sclerosis - genetics | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Cells, Cultured | Gene Expression Regulation - physiology | Mice, Transgenic | Toll-Like Receptor 2 - metabolism | Amyotrophic Lateral Sclerosis - blood | Coculture Techniques - methods | Mutation - genetics | Disease Progression | Microglia | Amyotrophic Lateral Sclerosis - pathology | Animals | Analysis of Variance | Interleukin-2 Receptor alpha Subunit - metabolism | Lectins - genetics | Aged | Mice | CX3C Chemokine Receptor 1 | CD4 Antigens - metabolism | Amyotrophic lateral sclerosis | Original
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2009, Volume 323, Issue 5918, pp. 1205 - 1208
Journal Article