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Journal of Clinical Oncology, ISSN 0732-183X, 04/2018, Volume 36, Issue 12, pp. 1199 - 1206
Journal Article
Leukemia, ISSN 0887-6924, 03/2019, Volume 33, Issue 3, pp. 696 - 709
TYK2 is a member of the JAK family of tyrosine kinases that is involved in chromosomal translocation-induced fusion proteins found in anaplastic large cell... 
NPM-ALK | ACTIVATION | FUSION | CYTOKINE RESPONSES | GENE | ONCOLOGY | STAT1 | TYROSINE KINASE | T-CELL | TYK2 | HEMATOLOGY | EXPRESSION | Apoptosis - drug effects | Humans | Cell Survival - genetics | Apoptosis - genetics | Translocation, Genetic - drug effects | Anaplastic Lymphoma Kinase - genetics | Phosphorylation - genetics | Protein-Tyrosine Kinases - genetics | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Gene Expression Regulation, Neoplastic - genetics | STAT3 Transcription Factor - genetics | Lymphoma, Large-Cell, Anaplastic - genetics | Cell Survival - drug effects | Signal Transduction - genetics | STAT1 Transcription Factor - genetics | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Animals | Signal Transduction - drug effects | Lymphoma, Large-Cell, Anaplastic - drug therapy | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | TYK2 Kinase - genetics | Translocation, Genetic - genetics | Non-Hodgkin's lymphomas | Research | Drug therapy | Gene expression | Tyk2 protein | Phosphorylation | Interleukin 22 | Kinases | Proteins | Receptors | Cell activation | Dependence | Autocrine signalling | Stat1 protein | Protein-tyrosine kinase | Tyrosine | Translocation | Cell survival | Stat3 protein | Survival | Lymphoma | Mcl-1 protein | Inhibitors | Cell lines | Interleukin 10 | Lymphomas | Anaplastic large-cell lymphoma | Tumors | Apoptosis | Index Medicus
Journal Article
Leukemia, ISSN 0887-6924, 11/2018, Volume 32, Issue 11, pp. 2435 - 2444
Journal Article
The Lancet Respiratory Medicine, ISSN 2213-2600, 06/2018, Volume 6, Issue 6, pp. 431 - 441
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 12510 - 11
Rearrangements of the anaplastic lymphoma kinase (ALK) gene in non-small cell lung cancer (NSCLC) represent a novel molecular target in a small subset of... 
GENE FUSIONS | SPITZ TUMORS | ASSAY | ANAPLASTIC LYMPHOMA-KINASE | MULTIDISCIPLINARY SCIENCES | FISH | CRIZOTINIB | RET FUSIONS | INFLAMMATORY MYOFIBROBLASTIC TUMORS | REARRANGEMENTS | MULTIPLEX | Lung Neoplasms - drug therapy | Oncogene Proteins, Fusion - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Antineoplastic Agents - therapeutic use | RNA, Messenger - metabolism | Case-Control Studies | Anaplastic Lymphoma Kinase - genetics | Adenocarcinoma of Lung - genetics | Adenocarcinoma of Lung - drug therapy | Anaplastic Lymphoma Kinase - metabolism | Female | High-Throughput Nucleotide Sequencing - instrumentation | High-Throughput Nucleotide Sequencing - methods | Dynactin Complex - genetics | Lung Neoplasms - genetics | Gene Expression | Carcinoma, Non-Small-Cell Lung - surgery | Crizotinib - therapeutic use | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | In Situ Hybridization, Fluorescence | Adenocarcinoma of Lung - surgery | Dynactin Complex - metabolism | Golgi Matrix Proteins - genetics | Oncogene Proteins, Fusion - genetics | Lung Neoplasms - surgery | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Adenocarcinoma of Lung - metabolism | Neoplasm Staging | Golgi Matrix Proteins - metabolism | Immunohistochemistry | Transcription | Lung cancer | Fluorescence in situ hybridization | Non-small cell lung carcinoma | Kinases | Lymphoma | Protein-tyrosine kinase | Tumors | Index Medicus | Life Sciences
Journal Article
Modern Pathology, ISSN 0893-3952, 05/2018, Volume 31, Issue 5, pp. 791 - 808
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 11/2018, Volume 18, Issue 1, pp. 1158 - 1158
Journal Article
Journal Article
Journal Article