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1. Enhanced recovery after anterior resection: earlier leak diagnosis and low mortality in a case series
by D'Souza, N and Robinson, PD and Branagan, G and Chave, H
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, ISSN 0035-8843, 09/2019, Volume 101, Issue 7, pp. 495 - 500
INTRODUCTION Early detection and treatment of anastomotic leak may mitigate its consequences. Within an enhanced recovery setting, the subtle signs of a leak... 
COLORECTAL SURGERY | SURGERY | RISK-FACTORS | METAANALYSIS | Rectal cancer | Enhanced recovery | SYMPTOMATIC ANASTOMOTIC LEAKAGE | DEFUNCTIONING STOMA | TOTAL MESORECTAL EXCISION | RECTAL-CANCER | Anterior resection | Anastomotic leak | DEHISCENCE
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2. Full Text Risk Factors for Anastomotic Leak After Colon Resection for Cancer: Multivariate Analysis and Nomogram From a Multicentric, Prospective, National Study With 3193 Patients
by Frasson, Matteo and Flor-Lorente, Blas and Rodríguez, José Luis Ramos and Granero-Castro, Pablo and Hervás, David and Alvarez Rico, Miguel Angel and Brao, Maria Jesus Garcia and Sánchez González, Juan Manuel and Garcia-Granero, Eduardo and ANACO Study Grp and ANACO Study Group
Annals of Surgery, ISSN 0003-4932, 08/2015, Volume 262, Issue 2, pp. 321 - 330
OBJECTIVE:To determine pre-/intraoperative risk factors for anastomotic leak after colon resection for cancer and to create a practical instrument for... 
nomogram | colon resection | risk factor | anastomotic leak | colon cancer | COLORECTAL SURGERY | SURGERY | MESORECTAL EXCISION | ANTERIOR RESECTION | DEFUNCTIONING STOMA | RECTAL-CANCER | PREDICTORS | OUTCOMES | GASTROINTESTINAL SURGERY | Multivariate Analysis | Predictive Value of Tests | Prospective Studies | Humans | Middle Aged | Risk Factors | Male | Anastomotic Leak - diagnosis | Colonic Neoplasms - complications | Incidence | Colonic Neoplasms - surgery | Spain - epidemiology | Anastomotic Leak - epidemiology | Colonic Neoplasms - pathology | Nomograms | Aged, 80 and over | Female | Aged | Colectomy - adverse effects | Anastomotic Leak - therapy
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3. Full Text Systematic review and meta‐analysis of use of serum C‐reactive protein levels to predict anastomotic leak after colorectal surgery
by Singh, P. P and Zeng, I. S. L and Srinivasa, S and Lemanu, D. P and Connolly, A. B and Hill, A. G
British Journal of Surgery, ISSN 0007-1323, 03/2014, Volume 101, Issue 4, pp. 339 - 346
Background Several recent studies have investigated the role of C‐reactive protein (CRP) as an early marker of anastomotic leakage following colorectal... 
SURGERY | INFLAMMATORY RESPONSE SYNDROME | PROSPECTIVE RANDOMIZED-TRIAL | RESECTION | LIKELIHOOD RATIOS | POSTOPERATIVE INFECTIVE COMPLICATIONS | PROCALCITONIN | GASTROINTESTINAL SURGERY | CANCER | DIAGNOSTIC-ACCURACY | Biomarkers - metabolism | C-Reactive Protein - metabolism | Postoperative Care | Epidemiologic Methods | Rectal Neoplasms - surgery | Humans | Anastomotic Leak - diagnosis | Usage | C-reactive protein | Swimming pools | Analysis
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4. Full Text Procalcitonin and C-Reactive Protein as Early Predictors of Anastomotic Leak in Colorectal Surgery: A Prospective Observational Study
by Garcia-Granero, Alvaro and Frasson, Matteo and Flor-Lorente, Blas and Blanco, Francisco and Puga, Ramon and Carratalá, Arturo and Garcia-Granero, Eduardo
Diseases of the Colon & Rectum, ISSN 0012-3706, 04/2013, Volume 56, Issue 4, pp. 475 - 483
BACKGROUND:Although the early diagnosis of anastomotic leak is a key point in reducing its clinical consequences, in daily practice, anastomotic leak diagnosis... 
Early diagnosis | Anastomosis leak | C-reactive protein | Procalcitonin | Blood biomarkers | Intestinal anastomosis | SURGERY | INFLAMMATORY RESPONSE SYNDROME | MANAGEMENT | RESECTION | PROGNOSIS | SEPSIS | RECTAL-CANCER | INTERNATIONAL MULTICENTER | COMPLICATIONS | INFECTION | MULTIVARIATE-ANALYSIS | GASTROENTEROLOGY & HEPATOLOGY | Calcitonin Gene-Related Peptide | Predictive Value of Tests | Calcitonin - blood | Prospective Studies | Protein Precursors - blood | Humans | Middle Aged | Postoperative Period | Male | Anastomotic Leak - diagnosis | Biomarkers - blood | Colon - surgery | Sensitivity and Specificity | Female | ROC Curve | Rectum - surgery | C-Reactive Protein - analysis | Early Diagnosis
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5. Full Text Predictors of Anastomotic Leak After Esophagectomy: An Analysis of The Society of Thoracic Surgeons General Thoracic Database
by Kassis, Edmund S., MD and Kosinski, Andrzej S., PhD and Ross, Patrick, MD, PhD and Koppes, Katherine E., PA-C and Donahue, James M., MD and Daniel, Vincent C., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2013, Volume 96, Issue 6, pp. 1919 - 1926
Background Anastomotic leak is an important cause of morbidity and mortality after esophagectomy. Few studies have targeted risk factors for the development of... 
Surgery | Cardiothoracic Surgery | MORTALITY | SURGERY | TRANSHIATAL ESOPHAGECTOMY | CARDIAC & CARDIOVASCULAR SYSTEMS | MORBIDITY | ESOPHAGUS | RESPIRATORY SYSTEM | VOLUME | OUTCOMES | CANCER | Prognosis | Follow-Up Studies | Humans | Middle Aged | Anastomotic Leak - etiology | Male | Esophagectomy - methods | Stomach - surgery | Esophageal Neoplasms - surgery | Anastomotic Leak - epidemiology | Aged, 80 and over | Female | Anastomosis, Surgical - methods | Retrospective Studies | Esophagus - surgery | Ohio - epidemiology | Databases, Factual | Morbidity - trends | Societies, Medical - statistics & numerical data | Survival Rate - trends | Risk Assessment | Risk Factors | Anastomotic Leak - diagnosis | Aged | Reconstructive Surgical Procedures | Databases | Physicians | Health aspects | Analysis | Mortality | Trade and professional associations
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6. Full Text Amylase in drain fluid for the diagnosis of pancreatic leak in post-pancreatic resection
by Davidson, Tsetsegdemberel Bat-Ulzii and Yaghoobi, Mohammad and Davidson, Brian R and Gurusamy, Kurinchi Selvan
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 04/2017, Volume 2017, Issue 4, p. CD012009
Background The treatment of people with clinically significant postoperative pancreatic leaks is different from those without clinically significant pancreatic... 
PANCREATICODUODENECTOMY | MEDICINE, GENERAL & INTERNAL | SYSTEMATIC REVIEWS | PROPER MANAGEMENT | HEAD RESECTION | METAANALYSIS | DISTAL PANCREATECTOMY | FISTULA | 1ST POSTOPERATIVE DAY | INTERNATIONAL STUDY-GROUP | RISK-ASSESSMENT | Prospective Studies | Amylases - analysis | Humans | Middle Aged | Biomarkers - analysis | Pancreatectomy | Clinical Enzyme Tests - standards | Male | Anastomotic Leak - diagnosis | Pancreaticoduodenectomy | Pancreas - surgery | Drainage | Sensitivity and Specificity | Female | Aged | Retrospective Studies
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7. Full Text Risk Factors and Consequences of Anastomotic Leak After Colectomy: A National Analysis
by Midura, Emily F and Hanseman, Dennis and Davis, Bradley R and Atkinson, Sarah J and Abbott, Daniel E and Shah, Shimul A and Paquette, Ian M
Diseases of the Colon & Rectum, ISSN 0012-3706, 03/2015, Volume 58, Issue 3, pp. 333 - 338
BACKGROUND:Previous research has identified a number of patient and operative factors associated with anastomotic leak after colectomy; however, a study that... 
Colectomy | Colon cancer | Anastomotic leak | Outcomes | COLORECTAL SURGERY | LOOP ILEOSTOMY | SURGERY | RECTAL-CANCER SURGERY | METAANALYSIS | DEFUNCTIONING STOMA | LOW ANTERIOR RESECTION | INTESTINAL ANASTOMOSES | PREDICTORS | MULTIVARIATE-ANALYSIS | GASTROENTEROLOGY & HEPATOLOGY | Smoking - adverse effects | Multivariate Analysis | United States - epidemiology | Outcome Assessment (Health Care) | Humans | Middle Aged | Colectomy - methods | Anastomosis, Surgical - adverse effects | Male | Anastomotic Leak - mortality | Incidence | Operative Time | Colonic Diseases - surgery | Reoperation - statistics & numerical data | Female | Anastomosis, Surgical - methods | Colectomy - adverse effects | Severity of Illness Index | Risk Factors | Anastomotic Leak - diagnosis | Quality Improvement | Drug Therapy - methods | Sex Factors | Patient Readmission - statistics & numerical data | Anastomotic Leak - physiopathology | Anastomotic Leak - therapy | Preoperative Care - methods | Index Medicus
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8. Full Text Self-expandable metal stents for the treatment of benign upper GI leaks and perforations
by Swinnen, Jo, MD and Eisendrath, Pierre, MD and Rigaux, Johanne, MD and Kahegeshe, Liliane, MD and Lemmers, Arnaud, MD, PhD and Le Moine, Olivier, MD, PhD and Devière, Jacques, MD, PhD
Gastrointestinal Endoscopy, ISSN 0016-5107, 2011, Volume 73, Issue 5, pp. 890 - 899
Background Self-expandable metal stents (SEMSs) have been suggested for the treatment of benign upper GI leaks and perforations. Nevertheless, uncomplicated... 
Gastroenterology and Hepatology | ANASTOMOTIC STRICTURES | ESOPHAGEAL-CARCINOMA | PLASTIC STENTS | MANAGEMENT | ENDOSCOPIC TREATMENT | BARIATRIC SURGERY | UPPER GASTROINTESTINAL-TRACT | DILATION | GASTROENTEROLOGY & HEPATOLOGY | FISTULAS | Device Removal | Follow-Up Studies | Deglutition Disorders - surgery | Humans | Mediastinal Diseases - diagnosis | Middle Aged | Anastomotic Leak - etiology | Male | Mediastinal Diseases - complications | Prosthesis Design | Esophageal Perforation - diagnosis | Young Adult | Time Factors | Deglutition Disorders - diagnosis | Mediastinal Diseases - surgery | Aged, 80 and over | Adult | Deglutition Disorders - etiology | Female | Endoscopy, Gastrointestinal - methods | Retrospective Studies | Bariatric Surgery - adverse effects | Esophagus - surgery | Iatrogenic Disease | Postoperative Complications | Stents | Anastomotic Leak - surgery | Esophagus - injuries | Rupture | Esophageal Perforation - surgery | Treatment Outcome | Anastomotic Leak - diagnosis | Esophageal Perforation - complications | Adolescent | Aged | Stent (Surgery) | C-reactive protein | Financial disclosure
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9. Full Text International multicenter experience with an over-the-scope clipping device for endoscopic management of GI defects (with video)
by Haito-Chavez, Yamile, MD and Law, Joanna K., MD and Kratt, Thomas, MD and Arezzo, Alberto, MD and Verra, Mauro, MD and Morino, Mario, MD and Sharaiha, Reem Z., MD and Poley, Jan-Werner, MD and Kahaleh, Michel, MD and Thompson, Christopher C., MD and Ryan, Michele B., MS and Choksi, Neel, MD and Elmunzer, B. Joseph, MD and Gosain, Sonia, MD and Goldberg, Eric M., MD and Modayil, Rani J., MD and Stavropoulos, Stavros N., MD and Schembre, Drew B., MD and DiMaio, Christopher J., MD and Chandrasekhara, Vinay, MD and Hasan, Muhammad K., MD and Varadarajulu, Shyam, MD and Hawes, Robert, MD and Gomez, Victoria, MD and Woodward, Timothy A., MD and Rubel-Cohen, Sergio, MD and Fluxa, Fernando, MD and Vleggaar, Frank P., MD and Akshintala, Venkata S., MD and Raju, Gottumukkala S., MD and Khashab, Mouen A., MD
Gastrointestinal Endoscopy, ISSN 0016-5107, 2014, Volume 80, Issue 4, pp. 610 - 622
Background The over-the-scope clip (OTSC) provides more durable and full-thickness closure as compared with standard clips. Only case reports and small case... 
Gastroenterology and Hepatology | IATROGENIC COLON PERFORATIONS | EXPANDABLE METAL STENTS | LOW ANTERIOR RESECTION | Y GASTRIC BYPASS | ANASTOMOTIC LEAK | GASTROINTESTINAL PERFORATIONS | MORBID-OBESITY | CASE SERIES | OTSC SYSTEM | GASTROENTEROLOGY & HEPATOLOGY | COLONOSCOPIC PERFORATIONS | Multivariate Analysis | Follow-Up Studies | Humans | Middle Aged | Male | Digestive System Fistula - diagnosis | Equipment Design | Gastrointestinal Diseases - diagnosis | Endoscopy, Gastrointestinal - instrumentation | Aged, 80 and over | Adult | Female | Endoscopy, Gastrointestinal - methods | Retrospective Studies | Equipment Safety | Anastomotic Leak - surgery | Tensile Strength | Digestive System Fistula - surgery | Logistic Models | Surgical Instruments | Treatment Outcome | International Cooperation | Anastomotic Leak - diagnosis | Academic Medical Centers | Intestinal Perforation - diagnosis | Intestinal Perforation - surgery | Suture Techniques - instrumentation | Gastrointestinal Diseases - surgery | Video Recording | Aged | Cohort Studies | Medical colleges | Endoscopic surgery | Endoscopy | Analysis | Index Medicus
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10. Full Text Identifying Patients at Higher Risk of Prolonged Air Leak After Lung Resection
by Gilbert, Sebastien, MD and Maghera, Sonam, BS and Seely, Andrew J., MD, PhD and Maziak, Donna E., MDCM, MS and Shamji, Farid M., MD and Sundaresan, Sudhir R., MD and Villeneuve, Patrick J., MD, PhD
Annals of Thoracic Surgery, ISSN 0003-4975, 2016, Volume 102, Issue 5, pp. 1674 - 1679
Background Predictive models of prolonged air leak have relied on information not always available preoperatively (eg, extent of resection, pleural adhesions).... 
Surgery | Cardiothoracic Surgery | POSTOPERATIVE PULMONARY COMPLICATIONS | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | RESPIRATORY SYSTEM | PREDICTORS | LOBECTOMY | SCORING SYSTEM | THORACIC-SURGERY | Pneumonectomy - adverse effects | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Risk Factors | Anastomosis, Surgical - adverse effects | Male | Anastomotic Leak - diagnosis | Pleural Diseases - diagnosis | Bronchi - surgery | Incidence | Pleural Diseases - epidemiology | Time Factors | Anastomotic Leak - epidemiology | Ontario - epidemiology | Female | Lung Neoplasms - surgery | ROC Curve | Aged | Retrospective Studies
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11. Full Text Recent improvements in the management of esophageal anastomotic leak after surgery for cancer
by Messager, Mathieu, MD and Warlaumont, Maxime, MD and Renaud, Florence, MD, PhD and Marin, Hélène, MD and Branche, Julien, MD and Piessen, Guillaume, MD, PhD and Mariette, Christophe, MD, PhD
European Journal of Surgical Oncology, ISSN 0748-7983, 2016, Volume 43, Issue 2, pp. 258 - 269
Abstract Anastomotic leakage following total gastrectomy or esophagectomy is a significant complication that considerably increases postoperative mortality.... 
Hematology, Oncology and Palliative Medicine | Surgery | Stomach | Review | Anastomotic leak | Esophagus | TOTAL GASTRECTOMY | RANDOMIZED CONTROLLED-TRIAL | ESOPHAGOGASTRIC ANASTOMOSIS | VACUUM-ASSISTED CLOSURE | COMPUTED-TOMOGRAPHY | CONTRAST SWALLOW | GASTRIC TUBE | ONCOLOGY | TERM CLINICAL-OUTCOMES | HAND-SEWN | CERVICAL ANASTOMOSIS | Anastomotic Leak - surgery | Esophageal Neoplasms - surgery | Humans | Risk Factors | Esophagectomy | Anastomotic Leak - diagnosis | Gastrectomy | Mortality | Algorithms | Endoscopy | Health aspects
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12. Full Text Routine intraoperative leak testing for sleeve gastrectomy: is the leak test full of hot air?
by Bingham, Jason, M.D and Lallemand, Michael, M.D and Barron, Morgan, M.D and Kuckelman, John, D.O and Carter, Preston, M.D and Blair, Kelly, M.D and Martin, Matthew, M.D
American Journal of Surgery, The, ISSN 0002-9610, 2016, Volume 211, Issue 5, pp. 943 - 947
Abstract Background Staple line leak after sleeve gastrectomy (SG) is a rare but dreaded complication with a reported incidence of 0% to 8%. Many surgeons... 
Surgery | Sleeve gastrectomy complications | Postoperative staple line leak | Intraoperative leak test | Bariatric surgery | Sleeve gastrectomy | Staple line dehiscence | SURGERY | SUMMIT | EXPERIENCE | UPDATE | Predictive Value of Tests | Surgical Stapling | Follow-Up Studies | Obesity, Morbid - surgery | Humans | Middle Aged | Anastomotic Leak - etiology | Postoperative Complications - prevention & control | Male | Young Adult | Gastrectomy - methods | Sensitivity and Specificity | Gastrectomy - adverse effects | Adult | Female | Retrospective Studies | Anastomotic Leak - surgery | Body Mass Index | Risk Assessment | Treatment Outcome | Anastomotic Leak - diagnosis | Obesity, Morbid - diagnosis | Intraoperative Care - methods | Adolescent | Cohort Studies | Surgeons | Studies | Body mass index | Obesity | Hospitals | Gastrointestinal surgery | Endoscopy | Defects
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13. Full Text Analysis of Unsuccessful Esophageal Stent Placements for Esophageal Perforation, Fistula, or Anastomotic Leak
by Freeman, Richard K., MD and Ascioti, Anthony J., MD and Giannini, Theresa, ARNP and Mahidhara, Raja J., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2012, Volume 94, Issue 3, pp. 959 - 965
Background Esophageal stent placement for the treatment of a perforation, anastomotic leak, or fistula has been adopted by some thoracic surgeons. Results have... 
Surgery | Cardiothoracic Surgery | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | RESPIRATORY SYSTEM | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Male | Treatment Outcome | Esophageal Fistula - diagnosis | Esophageal Perforation - therapy | Anastomotic Leak - diagnosis | Esophageal Perforation - diagnosis | Retreatment | Esophageal Fistula - therapy | Prosthesis Failure | Treatment Failure | Adult | Female | Aged | Esophagoscopy - methods | Retrospective Studies | Stents | Anastomotic Leak - therapy | Cohort Studies | Databases, Factual | Analysis | Fistula | Stent (Surgery)
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