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1. Full Text Phase II trial of bicalutamide in patients with androgen receptor-positive, estrogen receptor-negative metastatic breast cancer
by Gucalp, Ayca and Tolaney, Sara and Isakoff, Steven J and Ingle, James N and Liu, Minetta C and Carey, Lisa A and Blackwell, Kimberly and Rugo, Hope and Nabell, Lisle and Forero, Andres and Stearns, Vered and Doane, Ashley S and Danso, Michael and Moynahan, Mary Ellen and Momen, Lamia F and Gonzalez, Joseph M and Akhtar, Arooj and Giri, Dilip D and Patil, Sujata and Feigin, Kimberly N and Hudis, Clifford A and Traina, Tiffany A and Translational Breast Canc Res and Translational Breast Cancer Research Consortium (TBCRC 011) and on behalf of the Translational Breast Cancer Research Consortium (TBCRC 011)
Clinical cancer research, ISSN 1078-0432, 10/2013, Volume 19, Issue 19, pp. 5505 - 5512
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Tumors | Anilides - therapeutic use | Receptors, Estrogen - metabolism | Anilides - adverse effects | Humans | Middle Aged | Receptors, Androgen - metabolism | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Breast Neoplasms - metabolism | Nitriles - administration & dosage | Neoplasm Metastasis | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Hormones - blood | Tosyl Compounds - administration & dosage | Treatment Outcome | Breast Neoplasms - drug therapy | Tosyl Compounds - adverse effects | Anilides - administration & dosage | Breast Neoplasms - pathology | Tosyl Compounds - therapeutic use | Androgen Antagonists - therapeutic use | Breast Neoplasms - mortality | Aged | Androgen Antagonists - administration & dosage | Androgen Antagonists - adverse effects | Nitriles - adverse effects | Nitriles - therapeutic use | Index Medicus
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2. Full Text Androgen receptor antagonists for prostate cancer therapy
by Helsen, Christine and Van den Broeck, Thomas and Voet, Arnout and Prekovic, Stefan and Van Poppel, Hendrik and Joniau, Steven and Claessens, Frank
Endocrine-related cancer, ISSN 1351-0088, 08/2014, Volume 21, Issue 4, pp. T105 - T118
Thematic Review | Antiandrogen | Bicalutamide | Androgen receptor antagonist | Enzalutamide | Abiraterone | Prostate cancer | Oncology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Prostatic Neoplasms - metabolism | Androgen Receptor Antagonists - therapeutic use | Humans | Receptors, Androgen - metabolism | Male | Antineoplastic Agents - therapeutic use | Androgen Receptor Antagonists - pharmacology | Antineoplastic Agents - chemistry | Animals | Castration | Androgen Receptor Antagonists - chemistry | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - drug therapy | Index Medicus
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3. Full Text Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
by Arora, Vivek K and Schenkein, Emily and Murali, Rajmohan and Subudhi, Sumit K and Wongvipat, John and Balbas, Minna D and Shah, Neel and Cai, Ling and Efstathiou, Eleni and Logothetis, Chris and Zheng, Deyou and Sawyers, Charles L
Cell (Cambridge), ISSN 0092-8674, 12/2013, Volume 155, Issue 6, pp. 1309 - 1322
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasm Transplantation | Androgen Receptor Antagonists - therapeutic use | Phenylthiohydantoin - therapeutic use | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation | Transcriptome | Drug Resistance, Neoplasm | Male | Receptors, Glucocorticoid - metabolism | Phenylthiohydantoin - analogs & derivatives | Animals | Heterografts | Androgen Antagonists - therapeutic use | Mice | Prostatic Neoplasms - drug therapy | Disease Models, Animal | Index Medicus
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4. Non-Steroidal Androgen Receptor Antagonists and Prostate Cancer: A Survey on Chemical Structures Binding this Fast-Mutating Target
by Ferroni, Claudia and Varchi, Greta
Current medicinal chemistry, ISSN 0929-8673, 01/2019, Volume 26, Issue 33, pp. 6053 - 6073
Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Phenylthiohydantoin - chemistry | Anilides - therapeutic use | Androgen Receptor Antagonists - therapeutic use | Phenylthiohydantoin - therapeutic use | Humans | Receptors, Androgen - metabolism | Anilides - chemistry | Androstenes - therapeutic use | Drug Resistance, Neoplasm | Male | Tosyl Compounds - chemistry | Histone Deacetylase Inhibitors - chemistry | Phenylthiohydantoin - analogs & derivatives | Androstenes - chemistry | Receptors, Androgen - genetics | Androgen Receptor Antagonists - chemistry | Tosyl Compounds - therapeutic use | Nitriles - chemistry | Receptors, Androgen - chemistry | Histone Deacetylase Inhibitors - therapeutic use | Prostatic Neoplasms - drug therapy | Nitriles - therapeutic use | Surveys | Cytochrome | Organic chemistry | Androgens | Castration | Pathogenesis | Cytochrome P450 | Prostate cancer | Prostate | Cancer | Cytochromes P450
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5. Full Text Structure−Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC)
by Jung, Michael E and Ouk, Samedy and Yoo, Dongwon and Sawyers, Charles L and Chen, Charlie and Tran, Chris and Wongvipat, John
Journal of medicinal chemistry, ISSN 0022-2623, 04/2010, Volume 53, Issue 7, pp. 2779 - 2796
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Prostatic Neoplasms - pathology | Androgen Receptor Antagonists | Prostatic Neoplasms - surgery | Thiohydantoins - pharmacology | Receptors, Androgen - metabolism | Male | Structure-Activity Relationship | Thiohydantoins - chemical synthesis | Orchiectomy | Dose-Response Relationship, Drug | Xenograft Model Antitumor Assays | Androgens | Animals | Prostatic Neoplasms - genetics | Tumor Burden - drug effects | Thiohydantoins - therapeutic use | Cell Line, Tumor | Gene Expression Regulation, Neoplastic - drug effects | Thiohydantoins - chemistry | Prostatic Neoplasms - drug therapy | Index Medicus
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6. Full Text Revising the role of the androgen receptor in breast cancer
by Fioretti, F M and Sita-Lumsden, A and Bevan, C L and Brooke, G N
Journal of molecular endocrinology, ISSN 0952-5041, 06/2014, Volume 52, Issue 3, pp. R257 - R265
Review | Steroid | Breast cancer | Androgen receptors | Oestrogen receptor | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Anilides - therapeutic use | Signal Transduction | Humans | Receptors, Androgen - metabolism | Receptors, Estrogen - antagonists & inhibitors | Estrogen Antagonists - pharmacology | Triple Negative Breast Neoplasms - drug therapy | Abiraterone Acetate | Estrogen Antagonists - therapeutic use | Tamoxifen - therapeutic use | Tosyl Compounds - therapeutic use | Tamoxifen - pharmacology | Triple Negative Breast Neoplasms - pathology | Androgen Antagonists - therapeutic use | Female | Androstadienes - therapeutic use | Androgens - metabolism | Nitriles - therapeutic use | Index Medicus
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7. Full Text Androgen receptor antagonists in castration-resistant prostate cancer
by Rathkopf, Dana and Scher, Howard I
The cancer journal (Sudbury, Mass.), ISSN 1528-9117, 01/2013, Volume 19, Issue 1, pp. 43 - 49
androgen receptor antagonists | androgen receptor | antiandrogens | ARN-509 | Prostate cancer | enzalutamide | Life Sciences & Biomedicine | Oncology | Science & Technology | Prostatic Neoplasms - pathology | Androgen Receptor Antagonists - therapeutic use | Prostatic Neoplasms - surgery | Thiohydantoins - pharmacology | Humans | Receptors, Androgen - metabolism | Male | Clinical Trials as Topic | Orchiectomy | Animals | Antineoplastic Agents, Hormonal - therapeutic use | Thiohydantoins - therapeutic use | Neoplasm Staging | Prostatic Neoplasms - drug therapy | Index Medicus | prostate cancer
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8. Full Text Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)
by Gao, Wenqing and Dalton, James T
Drug discovery today, ISSN 1359-6446, 2007, Volume 12, Issue 5, pp. 241 - 248
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hormones. Endocrine system | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Androgen Antagonists - pharmacokinetics | Androgen Receptor Antagonists | Humans | Androgen Antagonists - pharmacology | Male | Organ Specificity | Drug Delivery Systems | Gene Expression Regulation - drug effects | Tissue Distribution | Androgens - pharmacology | Drug Design | Androgen Antagonists - therapeutic use | Androgens - pharmacokinetics | Androgens - therapeutic use | Female | Ligands | Index Medicus
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9. Full Text Role of androgen receptor splice variants, their clinical relevance and treatment options
by Wach, S and Taubert, H and Cronauer, M
World journal of urology, ISSN 0724-4983, 2019, Volume 38, Issue 3, pp. 647 - 656
Splice variant | Clinical relevance | AR-V | Androgen receptor | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Prostatic Neoplasms - metabolism | Alternative Splicing | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Male | RNA, Messenger - metabolism | Protein Domains - genetics | Prostatic Neoplasms, Castration-Resistant - genetics | Benzamides - therapeutic use | Prostatic Neoplasms - genetics | Protein Isoforms - metabolism | Antineoplastic Agents, Hormonal - therapeutic use | Isoindoles - therapeutic use | Lactams, Macrocyclic - therapeutic use | Benzhydryl Compounds - therapeutic use | Prostatic Neoplasms - drug therapy | Benzimidazoles - therapeutic use | Chlorohydrins - therapeutic use | RNA, Messenger - genetics | Binding Sites - genetics | Prostatic Neoplasms, Castration-Resistant - drug therapy | Enzyme Inhibitors - therapeutic use | Prostatic Neoplasms, Castration-Resistant - metabolism | Resorcinols - therapeutic use | Drug Resistance, Neoplasm - genetics | Receptors, Androgen - genetics | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Androgen Antagonists - therapeutic use | Androstadienes - therapeutic use | Isoxazoles - therapeutic use | Benzoquinones - therapeutic use | Proteins - antagonists & inhibitors | Niclosamide - therapeutic use | Protein Isoforms - genetics | Literature reviews | Alternative splicing | Androgens | Transcription | Clinical trials | Endocrine therapy | Prostate | Prostate cancer | Index Medicus
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