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1. Full Text Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors
by Ruili Huang and Menghang Xia and Ming-Hsuang Cho and Srilatha Sakamuru and Paul Shinn and Keith A. Houck and David J. Dix and Richard S. Judson and Kristine L. Witt and Robert J. Kaylock and Raymond R. Tice and Christopher P. Austin
Environmental health perspectives, ISSN 0091-6765, 8/2011, Volume 119, Issue 8, pp. 1142 - 1148
Chemical hazards | Receptors | Genomics | Environmental health | Agonists | Ligands | Cytotoxicity | Libraries | Environmental agencies | Research | Nuclear receptors | Chemical genomics | qHTS | Assay performance | Tox21 | Public, Environmental & Occupational Health | Environmental Sciences & Ecology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Environment. Living conditions | Public health. Hygiene-occupational medicine | Public health. Hygiene | Biological and medical sciences | Medical sciences | Peroxisome Proliferator-Activated Receptors - agonists | Cell Line | Retinoid X Receptor alpha - metabolism | Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors | Humans | Orphan Nuclear Receptors - agonists | Receptors, Androgen - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Thrombin - antagonists & inhibitors | Retinoid X Receptor alpha - agonists | Fragile X Mental Retardation Protein | Orphan Nuclear Receptors - antagonists & inhibitors | Retinoid X Receptor alpha - antagonists & inhibitors | PPAR gamma - antagonists & inhibitors | Receptors, Thrombin - agonists | Liver X Receptors | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Peroxisome Proliferator-Activated Receptors - metabolism | Receptors, Thrombin - metabolism | Estrogen Receptor alpha - metabolism | Environmental Pollutants - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Environmental aspects | Physiological aspects | Cell receptors | Health aspects | Chemicals | Index Medicus | nuclear receptors | assay performance | chemical genomics | cytotoxicity
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2. Full Text Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells
by Hiroyuki Kojima and Shinji Takeuchi and Naoto Uramaru and Kazumi Sugihara and Takahiko Yoshida and Shigeyuki Kitamura
Environmental health perspectives, ISSN 0091-6765, 8/2009, Volume 117, Issue 8, pp. 1210 - 1218
Hormone receptors | Hormone metabolism | Receptors | Dose response relationship | Cellular metabolism | Halogenated diphenyl ethers | Plasmids | Congeners | Flame retardants | Research | Ethers | Estrogen receptor | Androgen receptor | Glucocorticoid receptor | Reporter gene assay | Brominated diphenyl ether | Thyroid hormone receptor | Chinese hamster ovary cells | Public, Environmental & Occupational Health | Environmental Sciences & Ecology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Androgen Receptor Antagonists | Cricetinae | Receptors, Glucocorticoid - antagonists & inhibitors | Cricetulus | Humans | Thyroid Hormone Receptors beta - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Thyroid Hormone Receptors alpha - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - agonists | Halogenated Diphenyl Ethers - chemistry | Receptors, Glucocorticoid - agonists | Halogenated Diphenyl Ethers - metabolism | Androgens | Animals | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Thyroid Hormone Receptors beta - agonists | Molecular Structure | Thyroid Hormone Receptors alpha - agonists | Estrogen Receptor beta - antagonists & inhibitors | CHO Cells | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Metabolites | Health aspects | Polybrominated biphenyls | Index Medicus | glucocorticoid receptor | androgen receptor | thyroid hormone receptor | estrogen receptor | brominated diphenyl ether | reporter gene assay
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3. Full Text Phase II trial of bicalutamide in patients with androgen receptor-positive, estrogen receptor-negative metastatic breast cancer
by Gucalp, Ayca and Tolaney, Sara and Isakoff, Steven J and Ingle, James N and Liu, Minetta C and Carey, Lisa A and Blackwell, Kimberly and Rugo, Hope and Nabell, Lisle and Forero, Andres and Stearns, Vered and Doane, Ashley S and Danso, Michael and Moynahan, Mary Ellen and Momen, Lamia F and Gonzalez, Joseph M and Akhtar, Arooj and Giri, Dilip D and Patil, Sujata and Feigin, Kimberly N and Hudis, Clifford A and Traina, Tiffany A and Translational Breast Canc Res and Translational Breast Cancer Research Consortium (TBCRC 011) and on behalf of the Translational Breast Cancer Research Consortium (TBCRC 011)
Clinical cancer research, ISSN 1078-0432, 10/2013, Volume 19, Issue 19, pp. 5505 - 5512
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Pharmacology. Drug treatments | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Tumors | Anilides - therapeutic use | Receptors, Estrogen - metabolism | Anilides - adverse effects | Humans | Middle Aged | Receptors, Androgen - metabolism | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Breast Neoplasms - metabolism | Nitriles - administration & dosage | Neoplasm Metastasis | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Hormones - blood | Tosyl Compounds - administration & dosage | Treatment Outcome | Breast Neoplasms - drug therapy | Tosyl Compounds - adverse effects | Anilides - administration & dosage | Breast Neoplasms - pathology | Tosyl Compounds - therapeutic use | Androgen Antagonists - therapeutic use | Breast Neoplasms - mortality | Aged | Androgen Antagonists - administration & dosage | Androgen Antagonists - adverse effects | Nitriles - adverse effects | Nitriles - therapeutic use | Index Medicus
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4. Full Text Boron in Drug Discovery: Carboranes as Unique Pharmacophores in Biologically Active Compounds
by Issa, Fatiah and Kassiou, Michael and Rendina, Louis M
Chemical reviews, ISSN 0009-2665, 09/2011, Volume 111, Issue 9, pp. 5701 - 5722
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Receptors, Purinergic - chemistry | Receptors, Estrogen - metabolism | Receptors, Estrogen - agonists | Thymidine Kinase - chemistry | Humans | Receptors, Androgen - metabolism | Receptors, Estrogen - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | Receptors, Thrombin - chemistry | Drug Discovery | Receptors, Retinoic Acid - chemistry | Receptors, Purinergic - metabolism | Proteins - metabolism | Receptors, Estrogen - chemistry | Tumor Necrosis Factor-alpha - chemistry | Protein Kinase C - metabolism | Protein Kinase C - chemistry | Thymidine Kinase - metabolism | Receptors, Thrombin - metabolism | Ligands | Receptors, Androgen - chemistry | Proteins - chemistry | Boron Compounds | Receptors | Estrogen | Research | Hydrophobicity | Chemical properties | Structure | DNA-ligand interactions | Polycyclic compounds | Tretinoin | Drugs | Medicine | Boron | Carborane | Boron compounds | Index Medicus
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5. Full Text Androgen Receptor Function and Androgen Receptor–Targeted Therapies in Breast Cancer: A Review
by Kono, Miho and Fujii, Takeo and Lim, Bora and Karuturi, Meghan Sri and Tripathy, Debasish and Ueno, Naoto T
JAMA oncology, ISSN 2374-2437, 03/2017, Volume 3, Issue 9, pp. 1266 - 1273
Life Sciences & Biomedicine | Oncology | Science & Technology | Gene Expression | Phosphoinositide-3 Kinase Inhibitors | Phosphorylation | Androgen Receptor Antagonists - therapeutic use | Signal Transduction | Humans | Receptors, Androgen - metabolism | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Receptors, Estrogen - analysis | Molecular Targeted Therapy | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | Breast Neoplasms - chemistry | Receptors, Androgen - genetics | Biomarkers, Tumor - metabolism | Female | Receptor, ErbB-2 - analysis | Index Medicus
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6. Full Text Steroid receptor profiling of vinclozolin and its primary metabolites
by Molina-Molina, José-Manuel and Hillenweck, Anne and Jouanin, Isabelle and Zalko, Daniel and Cravedi, Jean-Pierre and Fernández, Mariana-Fátima and Pillon, Arnaud and Nicolas, Jean-Claude and Olea, Nicolás and Balaguer, Patrick
Toxicology and applied pharmacology, ISSN 0041-008X, 2006, Volume 216, Issue 1, pp. 44 - 54
Vinclozolin | Mineralocorticoid receptor | Androgen receptor | Glucocorticoid receptor | Estrogen receptors | Progesterone receptor | Fungicide | Reporter cell lines | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Pesticides, fertilizers and other agrochemicals toxicology | Medical sciences | Receptors, Mineralocorticoid - genetics | Androgen Receptor Antagonists | Receptors, Glucocorticoid - antagonists & inhibitors | Luciferases - metabolism | Receptors, Steroid - metabolism | Gene Expression - drug effects | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Androgen - metabolism | Anilides - chemistry | Tritium | Receptors, Glucocorticoid - metabolism | Receptors, Progesterone - genetics | Receptors, Steroid - antagonists & inhibitors | Receptors, Progesterone - antagonists & inhibitors | Luciferases - genetics | Receptors, Progesterone - metabolism | Dose-Response Relationship, Drug | Dexamethasone - pharmacology | Progesterone Congeners - pharmacology | Metribolone - pharmacology | Mineralocorticoid Receptor Antagonists | Estradiol - pharmacology | Carbamates - pharmacology | Cell Survival - drug effects | Oxazoles - metabolism | Androgen Antagonists - pharmacology | Anilides - metabolism | Aldosterone - pharmacology | Testosterone Congeners - pharmacology | Binding, Competitive - drug effects | Receptors, Androgen - genetics | Receptors, Steroid - genetics | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Promegestone - pharmacology | Oxazoles - pharmacology | Corticosteroids | Progesterone | Fungicides | Plant metabolites | Estrogen | Index Medicus | ANIMALS | ESTROGENS | METABOLITES | FUNGICIDES | GLUCOCORTICOIDS | PROGESTERONE | ERBIUM SULFIDES | 60 APPLIED LIFE SCIENCES | LUCIFERASE | RISK ASSESSMENT | LIGANDS | ANDROGENS | RECEPTORS
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7. Full Text Steroid-induced androgen receptor-oestradiol receptor β-Src complex triggers prostate cancer cell proliferation
by Abbondanza, Ciro and Domenico, Marina Di and de Falco, Antonietta and Ametrano, Donatella and Auricchio, Ferdinando and Castoria, Gabriella and Zannini, Maria Stella and Lombardi, Maria and Migliaccio, Antimo and Bilancio, Antonio and Barone, Maria Vittoria
The EMBO journal, ISSN 0261-4189, 10/2000, Volume 19, Issue 20, pp. 5406 - 5417
cross‐talk | androgen receptor | Src association | oestradiol receptor | Oestradiol receptor | Androgen receptor | Cross-talk | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Receptors, Androgen - metabolism | Estrogen Antagonists - pharmacology | Male | Recombinant Fusion Proteins - metabolism | src Homology Domains - drug effects | Transfection | Protein Binding - drug effects | src-Family Kinases - metabolism | Steroids - pharmacology | Tumor Cells, Cultured | Metribolone - pharmacology | Estradiol - pharmacology | Receptors, Estradiol - metabolism | Prostatic Neoplasms - pathology | Androgen Antagonists - pharmacology | Cell Division - drug effects | Macromolecular Substances | Animals | MAP Kinase Signaling System - drug effects | Receptors, Androgen - genetics | Androgens - pharmacology | Receptors, Estradiol - genetics | Models, Biological | Recombinant Fusion Proteins - genetics | src-Family Kinases - genetics | COS Cells | Index Medicus | cross-talk
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8. Full Text The prognostic impact of tumor cell expression of estrogen receptor‐α, progesterone receptor, and androgen receptor in patients irradiated for nonsmall cell lung cancer
by Rades, Dirk and Setter, Cornelia and Dahl, Olav and Schild, Steven E and Noack, Frank
Cancer, ISSN 0008-543X, 01/2012, Volume 118, Issue 1, pp. 157 - 163
radiotherapy | estrogen receptor‐α | androgen receptor | progesterone receptor | non‐small cell lung cancer | non-small cell lung cancer | estrogen receptor-α | Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the respiratory system and mediastinum | Biological and medical sciences | Medical sciences | Tumors | Pneumology | Carcinoma, Non-Small-Cell Lung - radiotherapy | Prognosis | Humans | Middle Aged | Carcinoma, Non-Small-Cell Lung - metabolism | Male | Carcinoma, Non-Small-Cell Lung - mortality | Receptors, Androgen - biosynthesis | Female | Aged | Estrogen Receptor alpha - biosynthesis | Retrospective Studies | Biomarkers, Tumor - biosynthesis | Receptors, Progesterone - biosynthesis | Index Medicus | Abridged Index Medicus
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