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Chemico-Biological Interactions, ISSN 0009-2797, 06/2015, Volume 234, pp. 309 - 319
Estrogens have important roles in the pathogenesis of endometrial cancer. They can have carcinogenic effects through stimulation of cell proliferation or... 
Aromatase pathway | Sulfatase pathway | Phase I and phase II estrogen metabolism | Aldo–keto reductase 1C3 (AKR1C3) | 17β-Hydroxysteroid dehydrogenases (17β-HSDs, HSD17B) | Catechol-O-methyl transferase (COMT) | 17b-Hydroxysteroid dehydrogenases | (17b-HSDs HSD17B)Aldoketo reductase 1C3 (AKR1C3) | 17 beta-Hydroxysteroid dehydrogenases (17 beta-HSDs, HSD17B) | DEHYDROGENASES | QUINONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROGESTERONE ACTION | 17-BETA-ESTRADIOL | CARCINOGENESIS | OVARIAN ENDOMETRIOSIS | Aldo-keto reductase 1C3 (AKR1C3) | ENZYMES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PHASE-I | CARCINOMA | PRE-RECEPTOR REGULATION | Sulfatases - genetics | Progesterone Reductase - metabolism | Humans | Endometrial Neoplasms - metabolism | Aromatase - metabolism | Catechol O-Methyltransferase - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Androstenedione - metabolism | Catechol O-Methyltransferase - metabolism | Aromatase - genetics | Endometrial Neoplasms - genetics | Sulfatases - metabolism | Estrogens - genetics | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Sulfotransferases - metabolism | Estrogens - metabolism | Quinones - pharmacology | Glutathione S-Transferase pi - genetics | Sulfotransferases - genetics | Estrone - genetics | Quinone Reductases - metabolism | Androstenedione - genetics | Glutathione S-Transferase pi - metabolism | Estrogens - biosynthesis | RNA, Messenger - genetics | Transcriptome - genetics | Progesterone Reductase - genetics | Arylsulfotransferase - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Estrone - analogs & derivatives | Aldo-Keto Reductase Family 1 Member C3 | Estrone - metabolism | Cell Line, Tumor | Quinone Reductases - genetics | 3-Hydroxysteroid Dehydrogenases - genetics | Arylsulfotransferase - metabolism | Physiological aspects | Endometrial cancer | Sulfates | Genes | Estrogen | Steroids | Index Medicus
Journal Article
Gene, ISSN 0378-1119, 10/2017, Volume 633, pp. 28 - 34
Leptin has been found to be involved in the ovarian granulosa cell apoptosis and steroidogenesis. Loss of neuropeptide Y (NPY) can correct the obesity syndrome... 
Neuropeptide Y | JAK2/STAT3 | Steroidogenesis | Leptin | Apoptosis | PROGESTERONE | FEMALE MICE | PORCINE GRANULOSA | NEUROPEPTIDE YY2 RECEPTOR | IDENTIFICATION | OBESE GENE | GENETICS & HEREDITY | SECRETION | SUBSTANCE-P | WEIGHT | GROWTH-FACTOR-I | Cell Proliferation | Janus Kinase 2 - biosynthesis | Apoptosis - drug effects | Humans | Leptin - metabolism | Apoptosis - genetics | Arginine - analogs & derivatives | Granulosa Cells - drug effects | Arginine - administration & dosage | Gene Knockdown Techniques | Neuropeptide Y - metabolism | Gonadal Steroid Hormones - genetics | Female | Progesterone - biosynthesis | Receptors, Neuropeptide Y - antagonists & inhibitors | Leptin - pharmacology | Neuropeptide Y - antagonists & inhibitors | Receptors, Neuropeptide Y - biosynthesis | STAT3 Transcription Factor - genetics | Androstenedione - genetics | Follicle Stimulating Hormone - metabolism | Dinoprostone - genetics | Granulosa Cells - physiology | Mice, Inbred C57BL | Janus Kinase 2 - genetics | Leptin - genetics | Benzazepines - pharmacology | STAT3 Transcription Factor - biosynthesis | Animals | Receptors, Neuropeptide Y - genetics | Arginine - pharmacology | Benzazepines - administration & dosage | Mice | Progesterone - genetics | Granulosa Cells - cytology | RNA, Small Interfering - metabolism | Animal experimentation | Analysis | Progesterone | Transforming growth factors | RNA | Children | Health aspects | Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 06/2004, Volume 96, Issue 12, pp. 936 - 945
Journal Article
Cancer Research, ISSN 0008-5472, 02/2010, Volume 70, Issue 3, pp. 1256 - 1264
textabstractAndrogen-deprivation therapy for prostate cancer (PC) eventually leads to castration-resistant PC (CRPC). Intratumoral androgen production might... 
XENOGRAFT MODELS | INCREASED EXPRESSION | ONCOLOGY | PATHWAY | IN-VIVO | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | AGGRESSIVENESS | RECEPTOR GENE | PROGRESSION | DIHYDROTESTOSTERONE | ANDROGEN DEPRIVATION THERAPY | Progesterone Reductase - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Neoplasms, Experimental - enzymology | Male | Transplantation, Heterologous | RNA, Messenger - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Androstenedione - metabolism | Pregnenolone - metabolism | Neoplasms, Experimental - pathology | Testosterone - metabolism | Prostatic Neoplasms - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Neoplasms, Experimental - genetics | Aged, 80 and over | 3-Hydroxysteroid Dehydrogenases - metabolism | Dihydrotestosterone - metabolism | Prostatic Neoplasms - pathology | RNA, Messenger - genetics | Progesterone Reductase - genetics | Reverse Transcriptase Polymerase Chain Reaction | Hydroxyprostaglandin Dehydrogenases - genetics | Orchiectomy | Gene Expression Regulation, Enzymologic | Animals | Aldo-Keto Reductase Family 1 Member C3 | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Steroid 17-alpha-Hydroxylase - genetics | Aged | Mice | Steroid 17-alpha-Hydroxylase - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 09/2012, Volume 97, Issue 9, pp. E1750 - E1757
Journal Article
Endocrinology, ISSN 0013-7227, 01/2012, Volume 153, Issue 1, pp. 450 - 461
Journal Article
Fertility and Sterility, ISSN 0015-0282, 2011, Volume 95, Issue 8, pp. 2683 - 2686
In a collaborative study, we investigated four 46,XX adolescent girls with Mayer-Rokitansky-Küster-Hauser syndrome and hyperandrogenism. Molecular analysis of... 
Internal Medicine | Obstetrics and Gynecology | steroidogenic enzymes regulation | atypical Mayer-Rokintansky-Küster-Hauser syndrome | hyperandrogenism | Wnt4 | mullerian aplasia | REPRODUCTIVE BIOLOGY | MUTATION | CATENIN | atypical Mayer-Rokintansky-Kuster-Hauser syndrome | OBSTETRICS & GYNECOLOGY | Abnormalities, Multiple - metabolism | Dehydroepiandrosterone - biosynthesis | Progesterone Reductase - metabolism | Humans | Uterus - metabolism | Vagina - abnormalities | RNA, Messenger - metabolism | Wnt Proteins - metabolism | Spine - abnormalities | Young Adult | 17-alpha-Hydroxyprogesterone - metabolism | Congenital Abnormalities | Transfection | Wnt Proteins - genetics | DNA Mutational Analysis | Female | Hyperandrogenism - metabolism | Mullerian Ducts - metabolism | Abnormalities, Multiple - genetics | Ovary - metabolism | Genetic Predisposition to Disease | 46, XX Disorders of Sex Development - genetics | Hyperandrogenism - genetics | Uterus - abnormalities | Progesterone Reductase - genetics | beta Catenin - metabolism | Mullerian Ducts - abnormalities | Phenotype | Kidney - abnormalities | Adolescent | Somites - abnormalities | Cell Line, Tumor | Heterozygote | Steroid 17-alpha-Hydroxylase - genetics | Vagina - metabolism | Steroid 17-alpha-Hydroxylase - metabolism | 46, XX Disorders of Sex Development - metabolism | Mutation | Androstenedione - biosynthesis | Wnt4 Protein | Physiological aspects | Genetic research | Teenage girls | Analysis | Cytochrome P-450 | Genes | Ovarian cancer | Index Medicus
Journal Article
Journal of Reproductive Immunology, ISSN 0165-0378, 2015, Volume 113, pp. 9 - 15
Journal Article
Journal Article
Biology of Reproduction, ISSN 0006-3363, 05/2008, Volume 78, Issue 5, pp. 939 - 946
The present study was designed to obtain new insights into fish gonadal sex differentiation by comparing the effects of two different masculinizing treatments... 
Testis | Ovary | Gene regulation | Early development | Steroid hormones | PLEURODELES-WALTL | OVARIAN DEVELOPMENT | ONCORHYNCHUS-MYKISS | DEPENDENT SEX DETERMINATION | ENVIRONMENTAL ASPECTS | testis | ANTI-MULLERIAN HORMONE | AROMATASE INHIBITOR | early development | ovary | REPRODUCTIVE BIOLOGY | TILAPIA OREOCHROMIS-NILOTICUS | gene regulation | GENE-EXPRESSION | PARALICHTHYS-OLIVACEUS | steroid hormones | Aromatase - metabolism | Male | Gene Expression Profiling | Androstatrienes - pharmacology | Receptors, Retinoic Acid - genetics | Testis - drug effects | DNA-Binding Proteins - metabolism | Androstenedione - analogs & derivatives | Aromatase - genetics | Oncorhynchus mykiss - physiology | Forkhead Transcription Factors - metabolism | DAX-1 Orphan Nuclear Receptor | Female | Ovary - drug effects | Estrogens - metabolism | Repressor Proteins - metabolism | Sex Differentiation - genetics | Enzyme Inhibitors - pharmacology | Repressor Proteins - genetics | Genotype | Oncorhynchus mykiss - genetics | Ovary - physiology | Receptors, Retinoic Acid - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Forkhead Transcription Factors - genetics | Androstenedione - pharmacology | Testis - physiology | Transcription Factors - metabolism | Sex Differentiation - physiology | Phenotype | Animals | Androgens - pharmacology | Index Medicus
Journal Article
Reproduction, ISSN 1470-1626, 2017, Volume 154, Issue 4, pp. 445 - 454
Equine fetuses have substantial circulating pregnenolone concentrations and thus have been postulated to provide significant substrate for placental 5... 
PREGNANT MAMMALS | REPRODUCTIVE BIOLOGY | NEWBORN FOAL | STEROID-HORMONE TRANSFORMATIONS | MARE | PROGESTERONE | PREPARATIONS IN-VITRO | LATE-GESTATION | DEVELOPMENTAL BIOLOGY | EXPRESSION | MASS-SPECTROMETRY | ENDOCRINE ORGANS | Dehydroepiandrosterone - biosynthesis | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Testis - metabolism | Progesterone Reductase - metabolism | Gonadal Steroid Hormones - biosynthesis | Androstenedione - blood | Aromatase - metabolism | Multienzyme Complexes - metabolism | Male | Gonadal Steroid Hormones - blood | Adrenal Glands - embryology | Embryo, Mammalian - metabolism | Cholesterol Side-Chain Cleavage Enzyme - genetics | Aromatase - genetics | Adrenal Cortex Hormones - biosynthesis | Testis - embryology | Gene Expression Regulation, Developmental | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Female | Steroid Isomerases - genetics | Pregnenolone - biosynthesis | Ovary - metabolism | Ovary - embryology | Steroid Isomerases - metabolism | Placenta - embryology | Dehydroepiandrosterone - blood | Multienzyme Complexes - genetics | Progesterone Reductase - genetics | Gestational Age | Gene Expression Regulation, Enzymologic | Placenta - metabolism | Pregnancy | Animals | Pregnenolone - blood | Adrenal Glands - metabolism | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Horses | Steroid 17-alpha-Hydroxylase - genetics | Steroid 17-alpha-Hydroxylase - metabolism | Adrenal Cortex Hormones - blood | Androstenedione - biosynthesis | Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 09/2007, Volume 92, Issue 9, pp. 3674 - 3680
Context: In male patients with congenital adrenal hyperplasia (CAH), testicular adrenal rest tumors are frequently found that may interfere with gonadal... 
TESTIS-SPARING SURGERY | LEYDIG-CELL TUMORS | ADRENOGENITAL SYNDROME | GENE | CORTEX | TESTOSTERONE | ADULT MALES | ENDOCRINOLOGY & METABOLISM | 11-BETA-HYDROXYLASE | EXPRESSION | REST TUMORS | Receptors, Angiotensin - metabolism | Adrenal Rest Tumor - metabolism | Humans | Middle Aged | Adrenal Cortex - metabolism | Androstenedione - blood | RNA, Messenger - analysis | Male | Adrenal Rest Tumor - physiopathology | Adrenal Hyperplasia, Congenital - genetics | Steroid 11-beta-Hydroxylase - genetics | RNA, Messenger - metabolism | Adrenal Rest Tumor - etiology | Receptors, Corticotropin - metabolism | Steroid 11-beta-Hydroxylase - blood | Cytochrome P-450 CYP11B2 - blood | Testicular Neoplasms - physiopathology | Steroid 21-Hydroxylase - genetics | Adult | Adrenal Rest Tumor - genetics | Cytochrome P-450 CYP11B2 - metabolism | Testis - blood supply | Testicular Neoplasms - genetics | Steroid 21-Hydroxylase - blood | Adrenal Hyperplasia, Congenital - metabolism | Testicular Neoplasms - metabolism | 17-alpha-Hydroxyprogesterone - blood | Adrenal Hyperplasia, Congenital - complications | Receptors, Angiotensin - genetics | Adrenal Cortex - physiopathology | Steroid 11-beta-Hydroxylase - metabolism | Testicular Neoplasms - etiology | Adrenal Hyperplasia, Congenital - physiopathology | Receptors, Corticotropin - genetics | Cytochrome P-450 CYP11B2 - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Molecular Human Reproduction, ISSN 1360-9947, 09/2014, Volume 21, Issue 3, pp. 255 - 261
The most pronounced effects of FSH signalling are potentially displayed in the follicle fluid, which acts as a reservoir for FSH-induced granulosa cell (GC)... 
Granulosa cell gene expression | Follicular fluid | FSHR polymorphisms | FSHR 307/680 | Sex steroids | sex steroids | MOLECULAR-BIOLOGY | STIMULATION | OVARIAN RESPONSE | DEVELOPMENTAL BIOLOGY | follicular fluid | PREGNANCY | OBSTETRICS & GYNECOLOGY | STEROID-PRODUCTION | WOMEN | IN-VITRO | REPRODUCTIVE BIOLOGY | granulosa cell gene expression | BIOCHEMISTRY | ASSOCIATION | GONADOTROPIN | Receptors, Transforming Growth Factor beta - genetics | Receptors, FSH - genetics | Humans | Receptors, Androgen - metabolism | Receptors, LH - metabolism | Aromatase - metabolism | Gene Expression Profiling | Androstenedione - metabolism | Granulosa Cells - metabolism | Receptors, Peptide - genetics | Testosterone - metabolism | Anti-Mullerian Hormone - genetics | Aromatase - genetics | Receptors, LH - genetics | Adult | Female | Gonadal Hormones - genetics | Menstrual Cycle - physiology | Receptors, FSH - metabolism | Estradiol - metabolism | Gene Expression Regulation | Cell Size | Genotype | Follicular Fluid - metabolism | Gonadal Hormones - metabolism | Follicular Fluid - chemistry | Receptors, Androgen - genetics | Receptors, Transforming Growth Factor beta - metabolism | Adolescent | Progesterone - metabolism | Polymorphism, Single Nucleotide | Anti-Mullerian Hormone - metabolism | Granulosa Cells - cytology | Receptors, Peptide - metabolism | Index Medicus | Clinical Medicine | Obstetrics, Gynecology and Reproductive Medicine | Reproduktionsmedicin och gynekologi | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 06/2013, Volume 161, Issue 6, pp. 1300 - 1308
Journal Article